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For patients with stage 4 or 5 chronic kidney disease and hepatitis C virus (HCV) infection, 12 weeks of treatment with glecaprevir and pibrentasvir results in a high rate of sustained virologic response, according to a study published online Oct. 11 in the New England Journal of Medicine. Edward Gane, M.D., from Auckland City Hospital in New Zealand, and colleagues conducted a multicenter trial to examine the efficacy and safety of combination treatment with the NS3/4A protease inhibitor glecaprevir and the NS5A inhibitor pibrentasvir for 12 weeks in adults with HCV infection and compensated liver disease with severe renal impairment, dependence on dialysis, or both. Participants had stage 4 or 5 chronic kidney disease. One hundred four patients were enrolled in the trial. The researchers found that the sustained virologic response rate was 98 percent. During treatment, none of the patients had virologic failure, and none had a virologic relapse after the end of treatment. Pruritus, fatigue, and nausea were reported in at least 10 percent of the patients. Twenty-four percent of the patients reported serious adverse events. Because of adverse events, four patients discontinued the trial treatment prematurely; three of these had sustained virologic response

Why is MedCab the Best Ambulance Service in Charbagh, Lucknow? Charbagh is located towards the South of Lucknow. The area is primarily known for Lucknow's largest railway station, the Charbagh Railway Station. Just like all the other regions of Lucknow, the area has a rich heritage and history. Charbagh is derived from a Persian term which means 'four gardens'. Just like the name, this area was developed as a large garden for the fourth Nawab of Awadh. With British rule and intervention, the area was developed into a railway station for better administration. Furthermore, Jawahar Lal Nehru and Mahatma Gandhi's first meeting also took place at this railway station in 1916. This makes the Charbagh Railway Station a site of great importance to Indian heritage and also holds exceptional value for the city of Lucknow. While the railway station accompanied by the beautiful botanical garden is the main attraction of Charbagh, there are also a number of hotels and residential places in the area, such as Lotus Apartments. The area also hosts several markets, such as the Shri Guru Nanak Market and Preet Market. The Charbagh Metro Station was also developed for ease of travel as a part of the red line of the Lucknow Metro. Besides this, the Lucknow City Hospital is also located in Charbagh. While Charbagh is an important area in Lucknow, arranging an ambulance for urgent medical needs may be challenging due to the heavy traffic in the area. However, MedCab can be contacted to meet urgent medical transportation needs at Charbagh, Lucknow. MedCab ambulances can arrive at Charbagh within minutes of being booked. A large range of high-tech facilities is present within our ambulances, including basic life support, ICU support, and critical patient care along with highly trained paramedics. Both intracity and intercity transportation are provided by MedCab. For the best and safest transport of the patient, call MedCab ambulance service at 18008-908-208.