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Matti Narkia

PLoS ONE: Vitamin D Status Is Positively Correlated with Regulatory T Cell Function in Patients with Multiple Sclerosis - 0 views

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    Vitamin D status is positively correlated with regulatory T cell function in patients with multiple sclerosis.\nSmolders J, Thewissen M, Peelen E, Menheere P, Cohen Tervaert JW, Damoiseaux J, Hupperts R.\nPLoS One. 2009 Aug 13;4(8):e6635.\nPMID: 19675671
Matti Narkia

Association study on two vitamin D receptor gene polymorphisms and vitamin D metabolites in multiple sclerosis. - Ann N Y Acad Sci. 2009 Sep;1173:515-20. - Wiley InterScience :: Article :: HTML Full Text - 0 views

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    Association study on two vitamin D receptor gene polymorphisms and vitamin D metabolites in multiple sclerosis. Smolders J, Damoiseaux J, Menheere P, Tervaert JW, Hupperts R. Ann N Y Acad Sci. 2009 Sep;1173:515-20. PMID: 19758194 DOI: 10.1111/j.1749-6632.2009.04656.x Discussion: We found no association of the Apal and Taql VDR gene SNPs with MS or with vitamin D metabolism in our population. Further research should assess the complex interaction between vitamin D, the VDR, and susceptibility to MS.
Matti Narkia

Vitamin D and multiple sclerosis. [Proc Soc Exp Biol Med. 1997] - PubMed Result - 0 views

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    Vitamin D and multiple sclerosis. Hayes CE, Cantorna MT, DeLuca HF. Proc Soc Exp Biol Med. 1997 Oct;216(1):21-7. Review. PMID: 9316607
Matti Narkia

Vitamin D: a natural inhibitor of multiple sclerosis - 0 views

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    Vitamin D: a natural inhibitor of multiple sclerosis. Hayes CE. Proc Nutr Soc. 2000 Nov;59(4):531-5. Review. PMID: 11115787
Matti Narkia

Vitamin D treatment in multiple sclerosis - ScienceDirect - Journal of the Neurological Sciences - 0 views

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    Vitamin D treatment in multiple sclerosis. Myhr KM. J Neurol Sci. 2009 Jun 22. [Epub ahead of print] PMID: 19549608 doi:10.1016/j.jns.2009.05.002 Epidemiological evidence combined with clinical and laboratory analyses, and experimental animal models, suggest a possible influence of vitamin D on MS susceptibility as well as clinical disease activity. Supplement with vitamin D may reduce the risk of developing MS. An intervention may also reduce the risk of conversion from a first clinical event suggestive of MS to clinical definite MS, as well as reduce the relapse rate among patients with relapsing remitting MS. More studies are, however, needed to determine optimal dose and serum level for vitamin D, as well as target populations and optimal timing for intervention.
Matti Narkia

Explaining multiple sclerosis prevalence by ultraviolet exposure: a geospatial analysis -- Beretich and Beretich 15 (8): 891 -- Multiple Sclerosis - 0 views

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    Explaining multiple sclerosis prevalence by ultraviolet exposure: a geospatial analysis. Beretich B, Beretich T. Mult Scler. 2009 Aug;15(8):891-8. PMID: 19667017 DOI: 10.1177/1352458509105579 Conclusion This analysis suggests a strong association between UV radiation and MS distribution, and an increase in risk for MS in those areas with a low UVI.
Matti Narkia

Higher levels of 25-hydroxyvitamin D are associated with a lower incidence of multiple sclerosis only in women -- Kragt et al. 15 (1): 9 -- Multiple Sclerosis - 0 views

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    Higher levels of 25-hydroxyvitamin D are associated with a lower incidence of multiple sclerosis only in women. Kragt J, van Amerongen B, Killestein J, Dijkstra C, Uitdehaag B, Polman Ch, Lips P. Mult Scler. 2009 Jan;15(1):9-15. Epub 2008 Aug 13. PMID: 18701572 DOI: 10.1177/1352458508095920 CONCLUSIONS: Our data suggest that higher circulating levels of 25(OH)D are associated with a lower incidence of MS and MS-related disability in women. This may imply clues to the pathogenesis of the sex difference in risk and to the nature of the environmental factors involved in MS.
Matti Narkia

JNNP -- eLetters for Soilu-Hänninen et al., 79 (2) 152-157 - 0 views

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    Vitamin D may suppress infections which lead to development of Multiple Sclerosis Steven R Brenner, None (16 August 2007) J Neurol Neurosurg Psychiatry 2008 I read the article with reference to the inverse relationship between multiple sclerosis clinical activity and deficiency of vitamin D by Soilu-Hannienen (1) with interest, and was considering what mechanism could be in play to cause such a relationship. 25-hydroxylated metabolites of vitamin D act as intracellular regulators of the synthesis and action of defensin (2) molecules against bacterial antigens, defensin being an endogenously synthesized antimicrobial substance (2). Human cathelicidin antimicrobial peptide gene is a target of vitamin D receptor and is strongly up-regulated by 1,25-dihydroxyvitamin D3, indicating vitamin D receptor and the 1,25-dihydroxyvitaminD3 regulate primate innate immunity (3)
Matti Narkia

A longitudinal study of serum 25-hydroxyvitamin D and intact parathyroid hormone levels indicate the importance of vitamin D and calcium homeostasis regulation in multiple sclerosis -- Soilu-Hänninen et al. 79 (2): 152 -- Journal of Neurology, Neurosurger - 0 views

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    A longitudinal study of serum 25-hydroxyvitamin D and intact parathyroid hormone levels indicate the importance of vitamin D and calcium homeostasis regulation in multiple sclerosis. Soilu-Hänninen M, Laaksonen M, Laitinen I, Erälinna JP, Lilius EM, Mononen I. J Neurol Neurosurg Psychiatry. 2008 Feb;79(2):152-7. Epub 2007 Jun 19. PMID: 17578859 doi:10.1136/jnnp.2006.105320 Conclusions: The endocrine circuitry regulating serum calcium may be altered in MS. There is an inverse relationship between serum vitamin D level and MS clinical activity. The role of vitamin D in MS must be explored further.
Matti Narkia

25-Hydroxyvitamin D levels in serum at the onset of multiple sclerosis -- Soilu-Hänninen et al. 11 (3): 266 -- Multiple Sclerosis - 0 views

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    25-Hydroxyvitamin D levels in serum at the onset of multiple sclerosis. Soilu-Hänninen M, Airas L, Mononen I, Heikkilä A, Viljanen M, Hänninen A. Mult Scler. 2005 Jun;11(3):266-71. PMID: 15957505 DOI: 10.1191/1352458505ms1157oa
Matti Narkia

Vitamin D Newsletter March 2009 | All Things Vitamin D - 0 views

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    This is a very long newsletter. I will answer questions about oil versus water-soluble Vitamin D, depression, mental clarity, malignant melanoma, Crohn's disease, an imagist poet, multiple sclerosis, sun-exposure, high-intensity red light and collagen repair in the skin, non-alcoholic fatty liver disease, influenza, the 1918 influenza pandemic, statins, the new Food and Nutrition Board, thyroid disease, chronic fatigue syndrome, athletes, the upcoming 14th Vitamin D Workshop, prostate cancer, the wrong blood test, pregnancy, autism, Alzheimer's disease, soap and sebum, asthma, sleep, the co-factors vitamin D needs to work (all contained in spinach), and-my favorite-UVC light and Vitamin D
Matti Narkia

Multiple Sclerosis Caused by Vitamin D Deficiency - 0 views

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    NaturalNews) Researchers from Oxford University and the University of British Columbia have discovered that Vitamin D deficiency affects a section of the human genome already linked with multiple sclerosis (MS) risk, adding further weight to theories that this vitamin deficiency might play a role in development of the disease. "Here we show that the main environmental risk candidate -- vitamin D -- and the main gene region are directly linked and interact," said co-author George Ebers.
Matti Narkia

High Prevalence of Vitamin D Inadequacy and Implications for Health - Mayo Clinic Proceedings - 0 views

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    High prevalence of vitamin D inadequacy and implications for health.\nHolick MF.\nMayo Clin Proc. 2006 Mar;81(3):353-73. Review.\nPMID: 16529140 \ndoi: 10.4065/​81.3.353\n
Matti Narkia

Vitamin D and multiple sclerosis. - Wiley InterScience - J Cell Biochem. 2008 Oct 1 - 0 views

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    Vitamin D and multiple sclerosis. Raghuwanshi A, Joshi SS, Christakos S. J Cell Biochem. 2008 Oct 1;105(2):338-43. Review. PMID: 18655192
Matti Narkia

Benefits and requirements of vitamin D for optimal health: a review - Altern Med Rev. 2005 Jun - 1 views

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    Grant WB, Holick MF. Benefits and requirements of vitamin D for optimal health: a review. Altern Med Rev. 2005 Jun;10(2):94-111. Review. PMID: 15989379
Matti Narkia

Vitamin D and autoimmunity: new aetiological and therapeutic considerations -- Arnson et al. 66 (9): 1137 -- Annals of the Rheumatic Diseases - 0 views

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    itamin D and autoimmunity: new aetiological and therapeutic considerations. Arnson Y, Amital H, Shoenfeld Y. Ann Rheum Dis. 2007 Sep;66(9):1137-42. Epub 2007 Jun 8. Review. PMID: 17557889 doi:10.1136/ard.2007.069831
Matti Narkia

Lack of sunshine found to trigger multiple sclerosis | Society | guardian.co.uk - 0 views

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    Research finds people with gene variant who lack vitamin D, produced from sun exposure, can develop condition
Matti Narkia

Vitamin D: A millenium perspective. - Wiley InterScience :: Article :: HTML Full Text - 0 views

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    Vitamin D: A millenium perspective. Holick MF. J Cell Biochem. 2003 Feb 1;88(2):296-307. Review. PMID: 12520530
Matti Narkia

JAMA -- Serum 25-Hydroxyvitamin D Levels and Risk of Multiple Sclerosis, December 20, 2006, Munger et al. 296 (23): 2832 - 0 views

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    Serum 25-hydroxyvitamin D levels and risk of multiple sclerosis. Munger KL, Levin LI, Hollis BW, Howard NS, Ascherio A. JAMA. 2006 Dec 20;296(23):2832-8. PMID: 17179460
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