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Matti Narkia

Correlation of symptoms with vitamin D deficiency and symptom response to cholecalcifer... - 0 views

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    Correlation of symptoms with vitamin D deficiency and symptom response to cholecalciferol treatment: a randomized controlled trial.
    Arvold DS, Odean MJ, Dornfeld MP, Regal RR, Arvold JG, Karwoski GC, Mast DJ, Sanford PB, Sjoberg RJ.
    Endocr Pract. 2009 May-Jun;15(3):203-12.
    PMID: 19364687

    Conclusions: Compared with participants in the placebo group, patients in the treatment group showed mild short-term improvement in the overall fibromyalgia impact score, but did not show significant improvement in most musculoskeletal symptoms or in activities of daily living.
Matti Narkia

Plasma Vitamin D and 25OHD Responses of Young and Old Men to Supplementation with Vitam... - 0 views

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    Plasma vitamin D and 25OHD responses of young and old men to supplementation with vitamin D3.
    Harris SS, Dawson-Hughes B.
    J Am Coll Nutr. 2002 Aug;21(4):357-62.
    PMID: 12166534

    Conclusions: There appears to be no age-related impairment among men in the absorption or metabolism of 20 µg/day of vitamin D3 taken orally for at least eight weeks.
Matti Narkia

Enzyme kinetics hypothesis to explain the U-shaped risk curve for prostate cancer vs. 2... - 0 views

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    Enzyme kinetics hypothesis to explain the U-shaped risk curve for prostate cancer vs. 25-hydroxyvitamin D in nordic countries.
    Vieth R.
    Int J Cancer. 2004 Sep 1;111(3):468; author reply 469.
    PMID: 15221979
    DOI: 10.1002/ijc.20218
Matti Narkia

Response -- Schwalfenberg 53 (9): 1435 -- Canadian Family Physician - 0 views

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    Vitamin D supplementation.
    Eveleigh B.
    Can Fam Physician. 2007 Sep;53(9):1435; author reply 1435.
    PMID: 17872869

    My concern regarding vitamin D2 is that it is a synthetic analogue and might interact with the vitamin D receptor differently in various cell systems. It has been reported that vitamin D3 might improve glycemic control.7 Vitamin D2 has been reported to cause worsening of glycemic control in people of East Indian descent.8 Is this because of vitamin D receptor polymorphism, or because of enhanced 24-hydroxylase enzyme activation, or is it due to how vitamin D2 interacts with the receptor? Until this has been sorted out, I feel safest using vitamin D3. There are about 2000 synthetic analogues of vitamin D. The search is on for one that can cross the blood-brain barrier to treat certain types of brain cancers without causing hypercalcemia.9 But then again, what other effects would this compound have? There are still so many unknowns
Matti Narkia

Vitamin D and the vitamin D receptor are critical for control of the innate immune resp... - 0 views

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    Conclusion

    The data point to a critical role for the VDR and 1,25(OH)2D3 in control of innate immunity and the response of the colon to chemical injury.

    Vitamin D and the vitamin D receptor are critical for control of the innate immune response to colonic injury.
    Froicu M, Cantorna MT.
    BMC Immunol. 2007 Mar 30;8:5.
    PMID: 17397543
    doi:10.1186/1471-2172-8-5
Matti Narkia

Exapation of an ancient Alu short interspersed element provides a highly conserved vita... - 0 views

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    Conclusion

    We demonstrated that the VDRE in the CAMP gene originated from the exaptation of an AluSx SINE in the lineage leading to humans, apes, OWMs and NWMs and remained under purifying selection for the last 55-60 million years. We present convincing evidence of an evolutionarily fixed, Alu-mediated divergence in steroid hormone nuclear receptor gene regulation between humans/primates and other mammals. Evolutionary selection to place the primate CAMP gene under regulation of the vitamin D pathway potentiates the innate immune response and may counter the anti-inflammatory properties of vitamin D.

    Exaptation of an ancient Alu short interspersed element provides a highly conserved vitamin D-mediated innate immune response in humans and primates.
    Gombart AF, Saito T, Koeffler HP.
    BMC Genomics. 2009 Jul 16;10:321.
    PMID: 19607716
    doi:10.1186/1471-2164-10-321
Matti Narkia

Vitamin D in defense of the human immune response. - Wiley InterScience :: JOURNALS :: ... - 0 views

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    Vitamin D in defense of the human immune response.\nAdams JS, Liu PT, Chun R, Modlin RL, Hewison M.\nAnn N Y Acad Sci. 2007 Nov;1117:94-105. Epub 2007 Jul 26. Review.\nPMID: 17656563\nDOI: 10.1196/annals.1402.03
Matti Narkia

Review: vitamin D, immunity and lupus. - Lupus. 2008 - 0 views

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    Review: vitamin D, immunity and lupus.
    Cutolo M, Otsa K.
    Lupus. 2008;17(1):6-10. Review.
    PMID: 18089676
    DOI: 10.1177/0961203307085879
Matti Narkia

Vitamin D3-Triggered Antimicrobial Response--Another Pleiotropic Effect beyond Mineral ... - 0 views

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    P.T. Liu, S. Stenger, H. Li, L. Wenzel, B.H. Tan, S.R. Krutzik, M.T. Ochoa, J. Schauber, K. Wu, C. Meinken, et al.\nVitamin D3-Triggered Antimicrobial Response--Another Pleiotropic Effect beyond Mineral and Bone Metabolism: Toll-Like Receptor Triggering of a Vitamin D-Mediated Human Antimicrobial Response. Science 311: 1770-1773, 2006\nJ. Am. Soc. Nephrol., November 1, 2006; 17(11): 2949 - 2953.
Matti Narkia

What is new in vitamin D: 2006-2007. - Current Opinion in Rheumatology - Abstract: Volu... - 0 views

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    Bikle DD.
    What is new in vitamin D: 2006-2007.
    Curr Opin Rheumatol. 2007 Jul;19(4):383-8.
    PMID: 17551371 [PubMed - in process]
Matti Narkia

Vitamin D and Its Role in Cancer and Immunity: A Prescription for Sunlight -- Mullin an... - 0 views

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    Mullin GE, Dobs A.
    Vitamin d and its role in cancer and immunity: a prescription for sunlight.
    Nutr Clin Pract. 2007 Jun;22(3):305-22. Review.
    PMID: 17507731 [PubMed - indexed for MEDLINE]
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