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Matti Narkia

Vitamin D supplement in early childhood and risk for Type I (insulin-dependent) diabete... - 0 views

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    Vitamin D supplement in early childhood and risk for Type I (insulin-dependent) diabetes mellitus. The EURODIAB Substudy 2 Study Group.
    [No authors listed]
    Diabetologia. 1999 Jan;42(1):51-4.
    PMID: 10027578
    DOI: 10.1007/s001250051112

    In conclusion, this large multicentre trial covering many different European settings consistently showed a protective effect of vitamin D supplementation in infancy. The findings indicate that activated vitamin D might contribute to immune modulation and thereby protect or arrest an ongoing immune process initiated in susceptible people by early environmental
    exposures.
Matti Narkia

YouTube - Vitamin D and Diabetes-Can We Prevent it? - 0 views

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    Frank Garland
Matti Narkia

Vitamin D in preventive medicine: are we ignoring the evidence? - 0 views

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    Vitamin D in preventive medicine: are we ignoring the evidence?
    Zittermann A.
    Br J Nutr. 2003 May;89(5):552-72. Review.
    PMID: 12720576

    Vitamin D is metabolised by a hepatic 25-hydroxylase into 25-hydroxyvitamin D (25(OH)D) and by a renal 1alpha-hydroxylase into the vitamin D hormone calcitriol. Calcitriol receptors are present in more than thirty different tissues. Apart from the kidney, several tissues also possess the enzyme 1alpha-hydroxylase, which is able to use circulating 25(OH)D as a substrate. Serum levels of 25(OH)D are the best indicator to assess vitamin D deficiency, insufficiency, hypovitaminosis, adequacy, and toxicity. European children and young adults often have circulating 25(OH)D levels in the insufficiency range during wintertime. Elderly subjects have mean 25(OH)D levels in the insufficiency range throughout the year. In institutionalized subjects 25(OH)D levels are often in the deficiency range. There is now general agreement that a low vitamin D status is involved in the pathogenesis of osteoporosis. Moreover, vitamin D insufficiency can lead to a disturbed muscle function. Epidemiological data also indicate a low vitamin D status in tuberculosis, rheumatoid arthritis, multiple sclerosis, inflammatory bowel diseases, hypertension, and specific types of cancer. Some intervention trials have demonstrated that supplementation with vitamin D or its metabolites is able: (i) to reduce blood pressure in hypertensive patients; (ii) to improve blood glucose levels in diabetics; (iii) to improve symptoms of rheumatoid arthritis and multiple sclerosis. The oral dose necessary to achieve adequate serum 25(OH)D levels is probably much higher than the current recommendations of 5-15 microg/d.
Matti Narkia

GrassrootsHealth | Vitamin D Action - Seminar - December 2008 - 0 views

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    Diagnosis and Treatment of Vitamin D Deficiency Seminar

    December 2, 2008
Matti Narkia

Not enough vitamin D: Health consequences for Canadians -- Schwalfenberg 53 (5): 841 --... - 0 views

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    Not enough vitamin D: health consequences for Canadians.
    Schwalfenberg G.
    Can Fam Physician. 2007 May;53(5):841-54. Review
    PMID: 17872747

    Conclusion

    Low levels of VTD are considered a major public health problem in Canada, especially during the winter. Those with risk factors should be screened for low 25(OH)D levels and repletion therapy instituted if needed. Researchers have estimated that the oral dose of vitamin D3 to attain and maintain 25(OH)D levels >80 nmol/L is 2200 IU/d if baseline levels are 20 to 40 nmol/L, 1800 IU/d if levels are 40 to 60 nmol/L, and 1160 IU/d if levels are between 60 and 80 nmol/L.64

    We need to ensure that patients have healthy blood levels of 25(OH)D to prevent levels of parathyroid hormone from rising and to maximize absorption of calcium, magnesium, and phosphate. Positive effects on bone are marginal at best unless patients consume at least 800 IU/d of VTD. The emerging and exciting role of the VTD receptor and the actions of VTD in maintaining health in other cell types have become more apparent during the last decade.
Matti Narkia

YouTube - Vitamin D and Diabetes-Can We Prevent it? - 0 views

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    Vitamin D and Diabetes-Can We Prevent it? Frank C. Garland
Matti Narkia

Vitamin D delivers multiple benefits | ajc.com - 0 views

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    Vitamin D may not just be good for you, it may help save your life.

    Recent research from Johns Hopkins University suggests that higher amounts of vitamin D in your diet decreases your likelihood of dying. Studies found that a vitamin D deficiency increases your risk of death by 26 percent, and vitamin D decreases the mortality rate from almost every type of cancer including breast, colon and prostate. Research also suggests that vitamin D helps prevent diabetes, kidney disease and cardiovascular disease.
Matti Narkia

Shedding light on vitamin D deficiency 'crisis' - Diet and nutrition- msnbc.com - 0 views

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    The vitamin D craze has been building over the last few years, with low levels of the supplement being the blamed as a source of many of our ills. Depression? D can ease it. Chronic pain? Take D. It is said to prevent kidney disease, diabetes, osteoporosis, colon and breast cancer, cardiovascular disease, or even the common cold. Recently, a study linked low vitamin D levels to the rise in Caesarean births.
Matti Narkia

Vitamin D and autoimmunity: new aetiological and therapeutic considerations -- Arnson e... - 0 views

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    itamin D and autoimmunity: new aetiological and therapeutic considerations.
    Arnson Y, Amital H, Shoenfeld Y.
    Ann Rheum Dis. 2007 Sep;66(9):1137-42. Epub 2007 Jun 8. Review.
    PMID: 17557889
    doi:10.1136/ard.2007.069831
Matti Narkia

Vitamin D: importance in the prevention of cancers, type 1 diabetes, heart disease, and... - 0 views

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    Vitamin D: importance in the prevention of cancers, type 1 diabetes, heart disease, and osteoporosis.\nHolick MF.\nAm J Clin Nutr. 2004 Mar;79(3):362-71. Review. Erratum in: Am J Clin Nutr. 2004 May;79(5):890.\nPMID: 14985208
Matti Narkia

Vitamin D deficiency an important, common, and easily treatable cardiovascular risk fac... - 0 views

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    Vitamin D deficiency an important, common, and easily treatable cardiovascular risk factor?\nLee JH, O'Keefe JH, Bell D, Hensrud DD, Holick MF.\nJ Am Coll Cardiol. 2008 Dec 9;52(24):1949-56. Review.\nPMID: 19055985
Matti Narkia

Too Little Vitamin D Puts Heart at Risk - 0 views

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    Dec. 1, 2008 -- Getting too little vitamin D may be an underappreciated heart disease risk factor that's actually easy to fix.\n\nResearchers say a growing body of evidence suggests that vitamin D deficiency increases the risk of heart disease and is linked to other, well-known heart disease risk factors such as high blood pressure, obesity, and diabetes.
Matti Narkia

Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, ... - 0 views

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    Holick MF.
    Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease.
    Am J Clin Nutr. 2004 Dec;80(6 Suppl):1678S-88S. Review.
    PMID: 15585788 [PubMed - indexed for MEDLINE]
Matti Narkia

Benefits and requirements of vitamin D for optimal health: a review - Altern Med Rev. 2... - 1 views

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    Grant WB, Holick MF.
    Benefits and requirements of vitamin D for optimal health: a review.
    Altern Med Rev. 2005 Jun;10(2):94-111. Review.
    PMID: 15989379
Matti Narkia

Vitamin D in preventive medicine: are we ignoring the evidence? Zittermann A - IngentaC... - 0 views

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    Zittermann A.
    Vitamin D in preventive medicine: are we ignoring the evidence?
    Br J Nutr. 2003 May;89(5):552-72. Review.
    PMID: 12720576 [PubMed - indexed for MEDLINE]
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