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Matti Narkia

Plasma Vitamin D and 25OHD Responses of Young and Old Men to Supplementation with Vitam... - 0 views

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    Plasma vitamin D and 25OHD responses of young and old men to supplementation with vitamin D3.
    Harris SS, Dawson-Hughes B.
    J Am Coll Nutr. 2002 Aug;21(4):357-62.
    PMID: 12166534

    Conclusions: There appears to be no age-related impairment among men in the absorption or metabolism of 20 µg/day of vitamin D3 taken orally for at least eight weeks.
Matti Narkia

Effect of four monthly oral vitamin D3 (cholecalciferol) supplementation on fractures a... - 1 views

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    Effect of four monthly oral vitamin D3 (cholecalciferol) supplementation on fractures and mortality in men and women living in the community: randomised double blind controlled trial.
    Trivedi DP, Doll R, Khaw KT.
    BMJ. 2003 Mar 1;326(7387):469.
    PMID: 12609940

    Conclusion: Four monthly supplementation with 100 000 IU oral vitamin D may prevent fractures without adverse effects in men and women living in the general community.
Matti Narkia

NEJM -- Vitamin D3 and calcium to prevent hip fractures in the elderly women - 0 views

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    Vitamin D3 and calcium to prevent hip fractures in the elderly women.
    Chapuy MC, Arlot ME, Duboeuf F, Brun J, Crouzet B, Arnaud S, Delmas PD, Meunier PJ.
    N Engl J Med. 1992 Dec 3;327(23):1637-42.
    PMID: 1331788

    CONCLUSIONS. Supplementation with vitamin D3 and calcium reduces the risk of hip fractures and other nonvertebral fractures among elderly women.
Matti Narkia

Can vitamin D supplementation prevent winter-time blues? A randomised trial among older... - 0 views

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    Can vitamin D supplementation prevent winter-time blues? A randomised trial among older women.
    Dumville JC, Miles JN, Porthouse J, Cockayne S, Saxon L, King C.
    J Nutr Health Aging. 2006 Mar-Apr;10(2):151-3.
    PMID: 16554952

    CONCLUSIONS: Supplementing elderly women with 800 IU of vitamin D daily did not lead to an improvement in mental health scores.
Matti Narkia

Dietary Acid-Base Balance, Bone Resorption, and Calcium Excretion -- Jajoo et al. 25 (3... - 0 views

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    Dietary acid-base balance, bone resorption, and calcium excretion.
    Jajoo R, Song L, Rasmussen H, Harris SS, Dawson-Hughes B.
    J Am Coll Nutr. 2006 Jun;25(3):224-30.
    PMID: 16766781

    Conclusions: Diet changes that increase renal NAE are associated with increases in serum PTH, bone resorption, and calcium excretion over a 60-day period.
Matti Narkia

NEJM -- Vitamin D3 and calcium to prevent hip fractures in the elderly women - 0 views

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    Vitamin D3 and calcium to prevent hip fractures in the elderly women.
    Chapuy MC, Arlot ME, Duboeuf F, Brun J, Crouzet B, Arnaud S, Delmas PD, Meunier PJ.
    N Engl J Med. 1992 Dec 3;327(23):1637-42.
    PMID: 1331788

    CONCLUSIONS. Supplementation with vitamin D3 and calcium reduces the risk of hip fractures and other nonvertebral fractures among elderly women.
Matti Narkia

Comparison of Daily, Weekly, and Monthly Vitamin D3 in Ethanol Dosing Protocols for Two... - 0 views

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    Comparison of daily, weekly, and monthly vitamin D3 in ethanol dosing protocols for two months in elderly hip fracture patients.
    Ish-Shalom S, Segal E, Salganik T, Raz B, Bromberg IL, Vieth R.
    J Clin Endocrinol Metab. 2008 Sep;93(9):3430-5. Epub 2008 Jun 10.
    PMID: 18544622
    doi:10.1210/jc.2008-0241

    CONCLUSIONS: Supplementation with vitamin D can be achieved equally well with daily, weekly, or monthly dosing frequencies. Therefore, the choice of dose frequency can be based on whichever approach will optimize an individual's adherence with long-term vitamin D supplementation.
Matti Narkia

Estimation of the dietary requirement for vitamin D in free-living adults >=64 y of age... - 0 views

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    Estimation of the dietary requirement for vitamin D in free-living adults >=64 y of age.
    Cashman KD, Wallace JM, Horigan G, Hill TR, Barnes MS, Lucey AJ, Bonham MP, Taylor N, Duffy EM, Seamans K, Muldowney S, Fitzgerald AP, Flynn A, Strain JJ, Kiely M.
    Am J Clin Nutr. 2009 May;89(5):1366-74. Epub 2009 Mar 18.
    PMID: 19297462
    doi:10.3945/ajcn.2008.27334

    Conclusion: To ensure that the vitamin D requirement is met by the vast majority (>97.5%) of adults aged ≥64 y during winter, between 7.9 and 42.8 µg vitamin D/d is required, depending on summer sun exposure and the threshold of adequacy of 25(OH)D. .
Matti Narkia

Effects of vitamin D and calcium supplementation on falls: a randomized controlled tria... - 0 views

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    Effects of vitamin D and calcium supplementation on falls: a randomized controlled trial.
    Bischoff HA, Stähelin HB, Dick W, Akos R, Knecht M, Salis C, Nebiker M, Theiler R, Pfeifer M, Begerow B, Lew RA, Conzelmann M.
    J Bone Miner Res. 2003 Feb;18(2):343-51.
    PMID: 12568412

    A single intervention with vitamin D plus calcium over a 3-month period reduced the risk of falling by 49% compared with calcium alone. Over this short-term intervention, recurrent fallers seem to benefit most by the treatment. The impact of vitamin D on falls might be explained by the observed improvement in musculoskeletal function.
Matti Narkia

How Much Vitamin D3 Do the Elderly Need? -- Viljakainen et al. 25 (5): 429 -- Journal o... - 0 views

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    How much vitamin D3 do the elderly need?
    Viljakainen HT, Palssa A, Kärkkäinen M, Jakobsen J, Lamberg-Allardt C.
    J Am Coll Nutr. 2006 Oct;25(5):429-35.
    PMID: 17031013

    Conclusions: A clear dose response was noted in S-25-OHD to different doses of vitamin D3. The recommended dietary intake of 15 µg is adequate to maintain the S-25-OHD concentration around 40-55 nmol/L during winter, but if the optimal S-25-OHD is higher than that even higher vitamin D intakes are needed. Interestingly, subjects with lower vitamin D status at baseline responded more efficiently to supplementation than those with more adequate status
Matti Narkia

Vitamin D supplementation improves neuromuscular function in older people who fall -- D... - 0 views

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    Vitamin D supplementation improves neuromuscular function in older people who fall.
    Dhesi JK, Jackson SH, Bearne LM, Moniz C, Hurley MV, Swift CG, Allain TJ.
    Age Ageing. 2004 Nov;33(6):589-95.
    PMID: 15501836
    doi:10.1093/ageing/afh20 9

    CONCLUSIONS: vitamin D supplementation, in fallers with vitamin D insufficiency, has a significant beneficial effect on functional performance, reaction time and balance, but not muscle strength. This suggests that vitamin D supplementation improves neuromuscular or neuroprotective function, which may in part explain the mechanism whereby vitamin D reduces falls and fractures.
Matti Narkia

JAMA -- Effect of Vitamin D on Falls: A Meta-analysis, April 28, 2004, Bischoff-Ferrari... - 0 views

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    Effect of Vitamin D on falls: a meta-analysis.
    Bischoff-Ferrari HA, Dawson-Hughes B, Willett WC, Staehelin HB, Bazemore MG, Zee RY, Wong JB.
    JAMA. 2004 Apr 28;291(16):1999-2006. Review.
    PMID: 15113819
Matti Narkia

High-dose oral vitamin D3 supplementation in the elderly. - [Osteoporos Int. 2009] - Pu... - 0 views

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    High-dose oral vitamin D3 supplementation in the elderly.
    Bacon CJ, Gamble GD, Horne AM, Scott MA, Reid IR.
    Osteoporos Int. 2009 Aug;20(8):1407-15. Epub 2008 Dec 20.
    PMID: 19101755

    Sixty-three elderly participants were randomized to three regimens of vitamin D supplementation: a 500,000-IU loading dose; the loading dose plus 50,000 IU/month; or 50,000 IU/month.

    CONCLUSIONS: Large loading doses of vitamin D(3) rapidly and safely normalize 25OHD levels in the frail elderly. Monthly dosing is similarly effective and safe, but takes 3-5 months for plateau 25OHD levels to be reached.
Matti Narkia

Vitamin D supplementation to prevent infections: a sub-study of a randomised placebo-co... - 0 views

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    Vitamin D supplementation to prevent infections: a sub-study of a randomised placebo-controlled trial in older people (RECORD trial, ISRCTN 51647438).\nAvenell A, Cook JA, Maclennan GS, Macpherson GC.\nAge Ageing. 2007 Sep;36(5):574-7. Epub 2007 Aug 15. No abstract available.\nPMID: 17702768 \ndoi:10.1093/ageing/afm091
Matti Narkia

The same annual dose of 292 000 IU of vitamin D(3) (cholecalciferol) on either daily or... - 0 views

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    The same annual dose of 292 000 IU of vitamin D(3) (cholecalciferol) on either daily or four monthly basis for elderly women: 1-year comparative study of the effects on serum 25(OH)D(3) concentrations and renal function.
    Pekkarinen T, Välimäki VV, Aarum S, Turpeinen U, Hämäläinen E, Löyttyniemi E, Välimäki MJ.
    Clin Endocrinol (Oxf). 2009 May 25. [Epub ahead of print]
    PMID: 19486025
    DOI: 10.1111/j.1365-2265.2009.03637.x
Matti Narkia

A higher dose of vitamin d reduces the risk of falls in nursing home residents: a rando... - 0 views

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    Broe KE, Chen TC, Weinberg J, Bischoff-Ferrari HA, Holick MF, Kiel DP. \nA higher dose of vitamin d reduces the risk of falls in nursing home residents: a randomized, multiple-dose study.\nJ Am Geriatr Soc. 2007 Feb;55(2):234-9.\nPMID: 17302660 [PubMed -
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