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Matti Narkia

Vitamin D and mortality in older men and women. - Clin Endocrinol (Oxf). 2009 Nov;71(5)... - 0 views

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    Vitamin D and mortality in older men and women.
    Pilz S, Dobnig H, Nijpels G, Heine RJ, Stehouwer CD, Snijder MB, van Dam RM, Dekker JM.
    Clin Endocrinol (Oxf). 2009 Nov;71(5):666-72. Epub 2009 Feb 18.
    PMID: 19226272
    DOI: 10.1111/j.1365-2265.2009.03548.x

    Conclusions Low 25(OH)D levels are associated with all-cause mortality and even more pronounced with cardiovascular mortality, but it remains unclear whether vitamin D deficiency is a cause or a consequence of a poor health status. Therefore, intervention studies are warranted to evaluate whether vitamin D supplementation reduces mortality and cardiovascular diseases.
Matti Narkia

Low serum 25-hydroxyvitamin D concentrations are associated with greater all-cause mort... - 0 views

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    Low serum 25-hydroxyvitamin D concentrations are associated with greater all-cause mortality in older community-dwelling women.
    Semba RD, Houston DK, Ferrucci L, Cappola AR, Sun K, Guralnik JM, Fried LP.
    Nutr Res. 2009 Aug;29(8):525-30.
    PMID: 19761886
    doi:10.1016/j.nutres.2009.07.007

    Older community-dwelling women with low 25(OH)D levels are at an increased risk of death.
Matti Narkia

Vitamin D Shows Heart Benefits in Study - Well Blog - NYTimes.com - 0 views

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    "A new study suggests many Americans aren't getting anywhere nearly enough of the vitamin, and it may be affecting their heart health.

    In the study, researchers looked at tens of thousands of healthy adults 50 and older whose vitamin D levels had been measured during routine checkups. A majority, they found, were deficient in the vitamin. About two-thirds had less vitamin D in their bloodstreams than the authors considered healthy, and many were extremely deficient.

    Less than two years later, the researchers found, those who had extremely low levels of the vitamin were almost twice as likely to have died or suffered a stroke than those with adequate amounts. They also had more coronary artery disease and were twice as likely to have developed heart failure.

    The findings, which are being presented today at an American Heart Association conference in Orlando, don't prove that lack of vitamin D causes heart disease; they only suggest a link between the two. "
Matti Narkia

Seniors With Insufficient Levels Of Vitamin D At Increased Risk Of Dying From Heart Dis... - 0 views

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    A new study by researchers at the University of Colorado Denver and Massachusetts General Hospital (MGH) shows vitamin D plays a vital role in reducing the risk of death associated with older age. The research, just published in the Journal of the American Geriatrics Society, evaluated the association between vitamin D levels in the blood and the death rates of those 65 and older. The study found that older adults with insufficient levels of vitamin D die from heart disease at greater rates that those with adequate levels of the vitamin.
Matti Narkia

Vitamin D Status and the Risk of Cardiovascular Disease Death -- Kilkkinen et al., 10.1... - 0 views

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    Vitamin D Status and the Risk of Cardiovascular Disease Death.
    Kilkkinen A, Knekt P, Aro A, Rissanen H, Marniemi J, Heliövaara M, Impivaara O, Reunanen A.
    Am J Epidemiol. 2009 Sep 17. [Epub ahead of print]
    PMID: 19762371
    doi:10.1093/aje/kwp227

    A low vitamin D level may be associated with higher risk of a fatal CVD event, particularly cerebrovascular death. These findings need to be replicated in other populations. To demonstrate a causal link between vitamin D and CVD, randomized controlled trials are required.
Matti Narkia

Independent Association of Low Serum 25-Hydroxyvitamin D and 1,25-Dihydroxyvitamin D Le... - 0 views

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    Independent association of low serum 25-hydroxyvitamin d and 1,25-dihydroxyvitamin d levels with all-cause and cardiovascular mortality.
    Dobnig H, Pilz S, Scharnagl H, Renner W, Seelhorst U, Wellnitz B, Kinkeldei J, Boehm BO, Weihrauch G, Maerz W.
    Arch Intern Med. 2008 Jun 23;168(12):1340-9.
    PMID: 18574092

    Conclusions Low 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D levels are independently associated with all-cause and cardiovascular mortality. A causal relationship has yet to be proved by intervention trials using vitamin D.
Matti Narkia

Are Serum 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D Levels Associated with Mortal... - 0 views

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    An estimated 50% to 60% of older people have suboptimal vitamin D levels, which is a problem that could affect more than bone health. Recent cross-sectional studies have also shown an association between low vitamin D levels and cardiovascular disease, hypertension, and metabolic syndrome. In a long-term prospective study from Germany, researchers assessed whether 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D levels were associated with all-cause and cardiovascular mortality among more than 3000 consecutive patients (mean age, 62) referred for coronary angiography.
Matti Narkia

Vitamin D and Death - Journal Watch Dermatology - 0 views

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    Vitamin D protects bone, preserves muscle strength, and regulates cell growth and energy metabolism. It also offers some protection against cancer and other disease, but are these effects really important for health and life expectancy? The answer seems to be a resounding yes.
Matti Narkia

Demographic Differences and Trends of Vitamin D Insufficiency in the US Population, 198... - 0 views

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    Demographic differences and trends of vitamin D insufficiency in the US population, 1988-2004.
    Ginde AA, Liu MC, Camargo CA Jr.
    Arch Intern Med. 2009 Mar 23;169(6):626-32.
    PMID: 19307527

    Conclusions National data demonstrate a marked decrease in serum 25(OH)D levels from the 1988-1994 to the 2001-2004 NHANES data collections. Racial/ethnic differences have persisted and may have important implications for known health disparities. Current recommendations for vitamin D supplementation are inadequate to address the growing epidemic of vitamin D insufficiency.
Matti Narkia

Mean Serum 25(OH)D Levels Decreasing in All Categories of the US Population - 0 views

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    March 27, 2009 - A significant decrease in serum 25-hydroxyvitamin D (25[OH]D) levels has led to an increase in vitamin D insufficiency in the US population, especially in racial and ethnic groups, according to results of a population-based study reported in the March 23 issue of the Archives of Internal Medicine.

    "Vitamin D insufficiency has been associated with increases in cardiovascular disease, cancer, and infection," write Adit A. Ginde, MD, from the Department of Emergency Medicine at the University of Colorado Denver School of Medicine, Aurora, Colorado, and colleagues. "Vitamin D supplementation appears to mitigate the incidence and adverse outcomes of these diseases and may reduce all-cause mortality."

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    "These findings have important implications for health disparities and public health," the study authors conclude. "Our data provide additional evidence that current recommendations for vitamin D supplementation (200-600 IU/d) are inadequate to achieve optimal serum 25(OH)D levels in most of the US population." They add that large, randomized controlled trials of higher doses of vitamin D supplementation are needed to evaluate their effect on general health and mortality.
Matti Narkia

Independent Association of Low Serum 25-Hydroxyvitamin D and 1,25-Dihydroxyvitamin D Le... - 0 views

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    Independent association of low serum 25-hydroxyvitamin d and 1,25-dihydroxyvitamin d levels with all-cause and cardiovascular mortality.\nDobnig H, Pilz S, Scharnagl H, Renner W, Seelhorst U, Wellnitz B, Kinkeldei J, Boehm BO, Weihrauch G, Maerz W.\nArch Intern Med. 2008 Jun 23;168(12):1340-9.\nPMID: 18574092
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