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Matti Narkia

Vitamin D Deficiency and Risk of Cardiovascular Disease -- Wang et al., 10.1161/CIRCULA... - 0 views

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    Vitamin D deficiency and risk of cardiovascular disease.
    Wang TJ, Pencina MJ, Booth SL, Jacques PF, Ingelsson E, Lanier K, Benjamin EJ, D'Agostino RB, Wolf M, Vasan RS.
    Circulation. 2008 Jan 29;117(4):503-11. Epub 2008 Jan 7.
    PMID: 18180395
    doi: 10.1161/CIRCULATIONAHA.107.706127

    Conclusions-Vitamin D deficiency is associated with incident cardiovascular disease. Further clinical and experimental studies may be warranted to determine whether correction of vitamin D deficiency could contribute to the prevention of cardiovascular disease.
Matti Narkia

Vitamin D and cardiovascular disease risk : Current Opinion in Clinical Nutrition & Met... - 0 views

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    Vitamin D and cardiovascular disease risk.
    Michos ED, Melamed ML.
    Curr Opin Clin Nutr Metab Care. 2008 Jan;11(1):7-12. Review.
    PMID: 18090651
    doi: 10.1097/MCO.0b013e3282f2f4dd

    Summary: Vitamin D deficiency is easy to screen for and easy to treat with supplementation. Further larger observational studies and randomized clinical trials are, however, needed to determine whether vitamin D supplementation could have any potential benefit in reducing future cardiovascular disease events and mortality risk.
Matti Narkia

Association of vitamin D deficiency with heart failure and sudden cardiac death in a la... - 0 views

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    Association of vitamin D deficiency with heart failure and sudden cardiac death in a large cross-sectional study of patients referred for coronary angiography.
    Pilz S, März W, Wellnitz B, Seelhorst U, Fahrleitner-Pammer A, Dimai HP, Boehm BO, Dobnig H.
    J Clin Endocrinol Metab. 2008 Oct;93(10):3927-35. Epub 2008 Aug 5.
    PMID: 18682515
    doi:10.1210/jc.2008-0784

    Conclusions: Low levels of 25(OH)D and 1,25(OH)2D are associated with prevalent myocardial dysfunction, deaths due to heart failure and SCD. Interventional trials are warranted to elucidate whether vitamin D supplementation is useful for treatment and/or prevention of myocardial diseases.
Matti Narkia

Serum 25-Hydroxyvitamin D Levels and the Prevalence of Peripheral Arterial Disease: Res... - 0 views

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    Serum 25-hydroxyvitamin D levels and the prevalence of peripheral arterial disease: results from NHANES 2001 to 2004.
    Melamed ML, Muntner P, Michos ED, Uribarri J, Weber C, Sharma J, Raggi P.
    Arterioscler Thromb Vasc Biol. 2008 Jun;28(6):1179-85. Epub 2008 Apr 16.
    PMID: 18417640
    doi: 10.1161/ATVBAHA.108.165886

    Conclusions- Low serum 25(OH)D levels are associated with a higher prevalence of PAD. Several mechanisms have been invoked in the literature to support a potential antiatherosclerotic activity of vitamin D. Prospective cohort and mechanistic studies should be designed to confirm this association.

    Vitamin D is an inhibitor of the renin-angiotensin system and has antiinflammatory and anticoagulant properties. Among 4839 NHANES 2001 to 2004 participants, low 25(OH)D levels were associated with a higher prevalence of PAD, after multivariate adjustment. To confirm this association, longitudinal cohort and mechanistic studies are needed.
Matti Narkia

Low Vitamin D Levels Predict Stroke in Patients Referred to Coronary Angiography -- Pil... - 0 views

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    Low vitamin d levels predict stroke in patients referred to coronary angiography.
    Pilz S, Dobnig H, Fischer JE, Wellnitz B, Seelhorst U, Boehm BO, März W.
    Stroke. 2008 Sep;39(9):2611-3. Epub 2008 Jul 17.
    PMID: 18635847
    doi: 10.1161/STROKEAHA.107.513655

    Conclusions- Low levels of 25(OH)D and 1,25(OH)2D are independently predictive for fatal strokes, suggesting that vitamin D supplementation is a promising approach in the prevention of strokes.
Matti Narkia

Independent Association of Low Serum 25-Hydroxyvitamin D and 1,25-Dihydroxyvitamin D Le... - 0 views

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    Independent association of low serum 25-hydroxyvitamin d and 1,25-dihydroxyvitamin d levels with all-cause and cardiovascular mortality.
    Dobnig H, Pilz S, Scharnagl H, Renner W, Seelhorst U, Wellnitz B, Kinkeldei J, Boehm BO, Weihrauch G, Maerz W.
    Arch Intern Med. 2008 Jun 23;168(12):1340-9.
    PMID: 18574092

    Conclusions Low 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D levels are independently associated with all-cause and cardiovascular mortality. A causal relationship has yet to be proved by intervention trials using vitamin D.
Matti Narkia

Vitamin D Deficiency and Risk of Cardiovascular Disease -- Wang et al. 117 (4): 503 -- ... - 0 views

  •  
    Vitamin D deficiency and risk of cardiovascular disease.
    Wang TJ, Pencina MJ, Booth SL, Jacques PF, Ingelsson E, Lanier K, Benjamin EJ, D'Agostino RB, Wolf M, Vasan RS.
    Circulation. 2008 Jan 29;117(4):503-11. Epub 2008 Jan 7.
    PMID: 18180395
    doi: 10.1161/CIRCULATIONAHA.107.706127

    Conclusions- Vitamin D deficiency is associated with incident cardiovascular disease. Further clinical and experimental studies may be warranted to determine whether correction of vitamin D deficiency could contribute to the prevention of cardiovascular disease.
Matti Narkia

25-Hydroxyvitamin D and Risk of Myocardial Infarction in Men: A Prospective Study, June... - 0 views

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    25-hydroxyvitamin D and risk of myocardial infarction in men: a prospective study.
    Giovannucci E, Liu Y, Hollis BW, Rimm EB.
    Arch Intern Med. 2008 Jun 9;168(11):1174-80.
    PMID: 18541825

    Conclusion Low levels of 25(OH)D are associated with higher risk of myocardial infarction in a graded manner, even after controlling for factors known to be associated with coronary artery disease.
Matti Narkia

Optimal vitamin D status attenuates the age-associated increase in systolic blood press... - 0 views

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    Optimal vitamin D status attenuates the age-associated increase in systolic blood pressure in white Americans: results from the third National Health and Nutrition Examination Survey.
    Judd SE, Nanes MS, Ziegler TR, Wilson PW, Tangpricha V.
    Am J Clin Nutr. 2008 Jan;87(1):136-41.
    PMID: 18175747

    Conclusions: SBP is inversely associated with serum vitamin D concentrations in nonhypertensive white persons in the United States. This observation provides a rationale for studies on the potential effects of vitamin D supplementation as a method to reduce SBP in persons at risk of hypertension.
Matti Narkia

Vitamin D: a D-Lightful health perspective. - Nutr Rev. 2008 Oct;66(10 Suppl 2):S182-94... - 0 views

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    Vitamin D: a D-Lightful health perspective.
    Holick MF.
    Nutr Rev. 2008 Oct;66(10 Suppl 2):S182-94. Review.
    PMID: 18844847
    DOI: 10.1111/j.1753-4887.2008.00104.x

    Sunlight provides most humans with their vitamin D requirement. Adequate vitamin D(3) by synthesis in the skin or from dietary and supplemental sources is essential for bone health throughout life. Vitamin D deficiency is defined as a 25(OH)D concentration <20 ng />30 ng/mL (75 nmol/L), and insufficiency as 21-29 ng/mL. Vitamin D deficiency and insufficiency has been linked to a wide variety of chronic diseases including common cancers, autoimmune, cardiovascular, and infectious diseases. Healthcare professionals need to be aware of the vitamin D deficiency pandemic. Guidelines for sensible sun exposure and supplemental vitamin D of 800-1000 IU/day are needed.
Matti Narkia

Plasma 25-Hydroxyvitamin D Levels and Risk of Incident Hypertension Among Young Women -... - 0 views

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    Plasma 25-hydroxyvitamin D levels and risk of incident hypertension among young women.
    Forman JP, Curhan GC, Taylor EN.
    Hypertension. 2008 Nov;52(5):828-32. Epub 2008 Oct 6.
    PMID: 18838623
    doi: 10.1161/HYPERTENSIONAHA.108.117630

    Women in the lowest compared with highest quartile of plasma 25(OH)D had an adjusted odds ratio for incident hypertension of 1.66 (95% CI: 1.11 to 2.48; P for trend=0.01). Compared with women with sufficient levels, those with vitamin D deficiency (<30 ng/mL; 65.7% of the study population) had a multivariable odds ratio of 1.47 (95% CI: 1.10 to 1.97). Plasma 25(OH)D levels are inversely and independently associated with the risk of developing hypertension.
Matti Narkia

High Prevalence of Vitamin D Inadequacy and Implications for Health - Mayo Clinic Pro... - 0 views

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    High prevalence of vitamin D inadequacy and implications for health.\nHolick MF.\nMayo Clin Proc. 2006 Mar;81(3):353-73. Review.\nPMID: 16529140 \ndoi: 10.4065/​81.3.353\n
Matti Narkia

Are Serum 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D Levels Associated with Mortal... - 0 views

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    An estimated 50% to 60% of older people have suboptimal vitamin D levels, which is a problem that could affect more than bone health. Recent cross-sectional studies have also shown an association between low vitamin D levels and cardiovascular disease, hypertension, and metabolic syndrome. In a long-term prospective study from Germany, researchers assessed whether 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D levels were associated with all-cause and cardiovascular mortality among more than 3000 consecutive patients (mean age, 62) referred for coronary angiography.
Matti Narkia

Association of vitamin D deficiency with heart failure and sudden cardiac death in a la... - 0 views

  •  
    Association of vitamin D deficiency with heart failure and sudden cardiac death in a large cross-sectional study of patients referred for coronary angiography.\nPilz S, März W, Wellnitz B, Seelhorst U, Fahrleitner-Pammer A, Dimai HP, Boehm BO, Dobnig H.\nJ Clin Endocrinol Metab. 2008 Oct;93(10):3927-35. Epub 2008 Aug 5.\nPMID: 18682515
Matti Narkia

Low vitamin d levels predict stroke in patients referred to coronary angiography. - Str... - 0 views

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    Low vitamin d levels predict stroke in patients referred to coronary angiography.\nPilz S, Dobnig H, Fischer JE, Wellnitz B, Seelhorst U, Boehm BO, März W.\nStroke. 2008 Sep;39(9):2611-3. Epub 2008 Jul 17.\nPMID: 18635847 \ndoi: 10.1161/STROKEAHA.107.513655
Matti Narkia

Vitamin D and cardiovascular disease risk. [Curr Opin Clin Nutr Metab Care. 2008] - Pub... - 0 views

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    Vitamin D and cardiovascular disease risk.
    Michos ED, Melamed ML.
    Curr Opin Clin Nutr Metab Care. 2008 Jan;11(1):7-12. Review.
    PMID: 18090651
Matti Narkia

Vitamin D deficiency an important, common, and easily treatable cardiovascular risk fac... - 0 views

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    Vitamin D deficiency an important, common, and easily treatable cardiovascular risk factor?\nLee JH, O'Keefe JH, Bell D, Hensrud DD, Holick MF.\nJ Am Coll Cardiol. 2008 Dec 9;52(24):1949-56. Review.\nPMID: 19055985
Matti Narkia

Independent Association of Low Serum 25-Hydroxyvitamin D and 1,25-Dihydroxyvitamin D Le... - 0 views

  •  
    Independent association of low serum 25-hydroxyvitamin d and 1,25-dihydroxyvitamin d levels with all-cause and cardiovascular mortality.\nDobnig H, Pilz S, Scharnagl H, Renner W, Seelhorst U, Wellnitz B, Kinkeldei J, Boehm BO, Weihrauch G, Maerz W.\nArch Intern Med. 2008 Jun 23;168(12):1340-9.\nPMID: 18574092
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