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Modeling biological systems is a significant task of systems biology and mathematical biology. Computational systems biology aims to develop and use efficient algorithms, data structures, visualization and communication tools with the goal of computer modeling of biological systems.

$32 million to develop a technology system designed to mimic the functions of specific organ systems representing a broad spectrum of human tissues, including the circulatory, musculoskeletal and nervous systems.""

the head of sakai explaining how he wants education to be open, not a black box and he doesn't want people to have to wait for their institution to get the best system.  Fascinating presentation. Highlighting that developers of LMS's share our vision so they're willining to cooperate if we approach in the right way. 

Here at PopSci we love a good broad agency announcement from DARPA (that's where they ask the private sector to do something technologically outrageous), but even next to the flying Humvees, the weather manipulation, the cyborg beetles, and the "hundred-year starships," this one, we have to say, is WAY out there. DARPA wants a genetic security system that's built into the genome that can monitor for and report on changes to an organism's genetic makeup.

Recent work in mice suggested that the immune system is involved in removing beta-amyloid, the main Alzheimer's-causing substance in the brain. Researchers have now shown for the first time that this may apply in humans

This is a fascinating piece exploring the world of electronics and its relation to biology. Particularly the nervous system. It explains the lessons we are learning from the brain in how to produce amazing efficient yet powerful computational devices. 

Welcome to JWS Online! JWS Online is a Systems Biology tool for simulation of kinetic models from a curated model database. Click on the Model Database tab to access the models, or on the other tabs for more information.

""We've learned that the same pathway that is activated strongly and prematurely in kids with progeria is also happening in you and me. That toxic protein they make from the beginning is also in our cells as we approach senescence. So cell senescence is not just a running down of the system - it's an active process. A signal turns on this protein." And that aging signal, Dr. Collins added, is connected to the shortening of the chromosome tips that serves as a cellular clock. So the glimpse into aging the kids with progeria provide may have illuminated a new risk factor that can damage blood vessels even in a star athlete who eats only broccoli."

Using this 3D body suit, they are able to shoot 3D motion capture right out of the lab. More details about this suit - known as MVN BIOMECH from Xsens, this 3D human kinematic, camera-less measurement system will come integrated with small tracking sensors that are placed on the joints. All the sensors on the suit will comprise of a trio of components: an accelerometer, magnetometers and a gyroscope, working in tandem to deliver information on each of the joints, body segments between the joints and the 3D movements. Currently, a project is being developed to see how nurses are able to lift patients safely into a hospital bed without having to strain themselves.

brilliant animation explaining how the nervous system is influenced by training and how to use this knowledge for better learning

Physicist Geoffrey West has found that simple, mathematical laws govern the properties of cities -- that wealth, crime rate, walking speed and many other aspects of a city can be deduced from a single number: the city's population. In this mind-bending talk from TEDGlobal he shows how it works and how similar laws hold for organisms and corporations. Physicist Geoffrey West believes that complex systems from organisms to cities are in many ways governed by simple laws -- laws that can be discovered and analyzed

"Scientists at the Luxembourg Centre for Systems Biomedicine (LCSB) of the University of Luxembourg have developed a model that makes predictions from which differentiated cells - for instance skin cells - can be very efficiently changed into completely different cell types - such as nerve cells, for example. This can be done entirely without stem cells. These computer-based instructions for reprogramming cells are of huge significance for regenerative medicine"

Great intro to doing work quickly and well About 46' in simulated evolution becomes an example. It's fascinating to hear what computer models of evolution have shown about evolving the ability to fly. 6 separate organ systems needed to mature before flight become possible. 

BioModels Database is a repository of peer-reviewed, published, computational models. These mathematical models are primarily from the field of systems biology, but more generally are those of biological interest. This resource allows biologists to store, search and retrieve published mathematical models.

This fancy strip of torso garb keeps tabs on a patient's heart rate, temperature, and other vital signs as well as their position inside of the hospital itself with a GPS-like system that functions in closed spaces. This intelligent t-shirt can also detect the patient's position - if they're sitting, lying down, standing, walking, or running.

The Living Human Project (LHP) is developing a worldwide, distributed repository of anatomo-functional data and of simulation algorithms relative to the human musculoskeletal apparatus, fully integrated into a seamless simulation environment and directly accessible by any researcher in the world. This infrastructure will be used to create the physiome of the human musculoskeletal system.

Lab investigating the networks in biological systems. Heard interview of mark gerstein on futures in biotech 83 explaining networks in protein bioinformatics

'Google Map' of human metabolism could pave way for new medical treatments

We speculate that the main selective pressures that have acted on regeneration are how first wounds are healed, and second, whether glial cells can retain access to embryonic genetic programmes to undertake neurogenesis. The latter may have limited CNS complexity in regenerative organisms.

This very cool... much like Google Wave... so now we can all work on a Google doc with real time commentary..only works for new documents ... check out the video on the link