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How Does Science Really Work? | The New Yorker - 1 views

  • I wanted to be a scientist. So why did I find the actual work of science so boring? In college science courses, I had occasional bursts of mind-expanding insight. For the most part, though, I was tortured by drudgery.
  • I’d found that science was two-faced: simultaneously thrilling and tedious, all-encompassing and narrow. And yet this was clearly an asset, not a flaw. Something about that combination had changed the world completely.
  • “Science is an alien thought form,” he writes; that’s why so many civilizations rose and fell before it was invented. In his view, we downplay its weirdness, perhaps because its success is so fundamental to our continued existence.
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  • In school, one learns about “the scientific method”—usually a straightforward set of steps, along the lines of “ask a question, propose a hypothesis, perform an experiment, analyze the results.”
  • That method works in the classroom, where students are basically told what questions to pursue. But real scientists must come up with their own questions, finding new routes through a much vaster landscape.
  • Since science began, there has been disagreement about how those routes are charted. Two twentieth-century philosophers of science, Karl Popper and Thomas Kuhn, are widely held to have offered the best accounts of this process.
  • For Popper, Strevens writes, “scientific inquiry is essentially a process of disproof, and scientists are the disprovers, the debunkers, the destroyers.” Kuhn’s scientists, by contrast, are faddish true believers who promulgate received wisdom until they are forced to attempt a “paradigm shift”—a painful rethinking of their basic assumptions.
  • Working scientists tend to prefer Popper to Kuhn. But Strevens thinks that both theorists failed to capture what makes science historically distinctive and singularly effective.
  • Sometimes they seek to falsify theories, sometimes to prove them; sometimes they’re informed by preëxisting or contextual views, and at other times they try to rule narrowly, based on t
  • Why do scientists agree to this scheme? Why do some of the world’s most intelligent people sign on for a lifetime of pipetting?
  • Strevens thinks that they do it because they have no choice. They are constrained by a central regulation that governs science, which he calls the “iron rule of explanation.” The rule is simple: it tells scientists that, “if they are to participate in the scientific enterprise, they must uncover or generate new evidence to argue with”; from there, they must “conduct all disputes with reference to empirical evidence alone.”
  • , it is “the key to science’s success,” because it “channels hope, anger, envy, ambition, resentment—all the fires fuming in the human heart—to one end: the production of empirical evidence.”
  • Strevens arrives at the idea of the iron rule in a Popperian way: by disproving the other theories about how scientific knowledge is created.
  • The problem isn’t that Popper and Kuhn are completely wrong. It’s that scientists, as a group, don’t pursue any single intellectual strategy consistently.
  • Exploring a number of case studies—including the controversies over continental drift, spontaneous generation, and the theory of relativity—Strevens shows scientists exerting themselves intellectually in a variety of ways, as smart, ambitious people usually do.
  • “Science is boring,” Strevens writes. “Readers of popular science see the 1 percent: the intriguing phenomena, the provocative theories, the dramatic experimental refutations or verifications.” But, he says,behind these achievements . . . are long hours, days, months of tedious laboratory labor. The single greatest obstacle to successful science is the difficulty of persuading brilliant minds to give up the intellectual pleasures of continual speculation and debate, theorizing and arguing, and to turn instead to a life consisting almost entirely of the production of experimental data.
  • Ultimately, in fact, it was good that the geologists had a “splendid variety” of somewhat arbitrary opinions: progress in science requires partisans, because only they have “the motivation to perform years or even decades of necessary experimental work.” It’s just that these partisans must channel their energies into empirical observation. The iron rule, Strevens writes, “has a valuable by-product, and that by-product is data.”
  • Science is often described as “self-correcting”: it’s said that bad data and wrong conclusions are rooted out by other scientists, who present contrary findings. But Strevens thinks that the iron rule is often more important than overt correction.
  • Eddington was never really refuted. Other astronomers, driven by the iron rule, were already planning their own studies, and “the great preponderance of the resulting measurements fit Einsteinian physics better than Newtonian physics.” It’s partly by generating data on such a vast scale, Strevens argues, that the iron rule can power science’s knowledge machine: “Opinions converge not because bad data is corrected but because it is swamped.”
  • Why did the iron rule emerge when it did? Strevens takes us back to the Thirty Years’ War, which concluded with the Peace of Westphalia, in 1648. The war weakened religious loyalties and strengthened national ones.
  • Two regimes arose: in the spiritual realm, the will of God held sway, while in the civic one the decrees of the state were paramount. As Isaac Newton wrote, “The laws of God & the laws of man are to be kept distinct.” These new, “nonoverlapping spheres of obligation,” Strevens argues, were what made it possible to imagine the iron rule. The rule simply proposed the creation of a third sphere: in addition to God and state, there would now be science.
  • Strevens imagines how, to someone in Descartes’s time, the iron rule would have seemed “unreasonably closed-minded.” Since ancient Greece, it had been obvious that the best thinking was cross-disciplinary, capable of knitting together “poetry, music, drama, philosophy, democracy, mathematics,” and other elevating human disciplines.
  • We’re still accustomed to the idea that a truly flourishing intellect is a well-rounded one. And, by this standard, Strevens says, the iron rule looks like “an irrational way to inquire into the underlying structure of things”; it seems to demand the upsetting “suppression of human nature.”
  • Descartes, in short, would have had good reasons for resisting a law that narrowed the grounds of disputation, or that encouraged what Strevens describes as “doing rather than thinking.”
  • In fact, the iron rule offered scientists a more supple vision of progress. Before its arrival, intellectual life was conducted in grand gestures.
  • Descartes’s book was meant to be a complete overhaul of what had preceded it; its fate, had science not arisen, would have been replacement by some equally expansive system. The iron rule broke that pattern.
  • by authorizing what Strevens calls “shallow explanation,” the iron rule offered an empirical bridge across a conceptual chasm. Work could continue, and understanding could be acquired on the other side. In this way, shallowness was actually more powerful than depth.
  • it also changed what counted as progress. In the past, a theory about the world was deemed valid when it was complete—when God, light, muscles, plants, and the planets cohered. The iron rule allowed scientists to step away from the quest for completeness.
  • The consequences of this shift would become apparent only with time
  • In 1713, Isaac Newton appended a postscript to the second edition of his “Principia,” the treatise in which he first laid out the three laws of motion and the theory of universal gravitation. “I have not as yet been able to deduce from phenomena the reason for these properties of gravity, and I do not feign hypotheses,” he wrote. “It is enough that gravity really exists and acts according to the laws that we have set forth.”
  • What mattered, to Newton and his contemporaries, was his theory’s empirical, predictive power—that it was “sufficient to explain all the motions of the heavenly bodies and of our sea.”
  • Descartes would have found this attitude ridiculous. He had been playing a deep game—trying to explain, at a fundamental level, how the universe fit together. Newton, by those lights, had failed to explain anything: he himself admitted that he had no sense of how gravity did its work
  • Strevens sees its earliest expression in Francis Bacon’s “The New Organon,” a foundational text of the Scientific Revolution, published in 1620. Bacon argued that thinkers must set aside their “idols,” relying, instead, only on evidence they could verify. This dictum gave scientists a new way of responding to one another’s work: gathering data.
  • Quantum theory—which tells us that subatomic particles can be “entangled” across vast distances, and in multiple places at the same time—makes intuitive sense to pretty much nobody.
  • Without the iron rule, Strevens writes, physicists confronted with such a theory would have found themselves at an impasse. They would have argued endlessly about quantum metaphysics.
  • ollowing the iron rule, they can make progress empirically even though they are uncertain conceptually. Individual researchers still passionately disagree about what quantum theory means. But that hasn’t stopped them from using it for practical purposes—computer chips, MRI machines, G.P.S. networks, and other technologies rely on quantum physics.
  • One group of theorists, the rationalists, has argued that science is a new way of thinking, and that the scientist is a new kind of thinker—dispassionate to an uncommon degree.
  • As evidence against this view, another group, the subjectivists, points out that scientists are as hopelessly biased as the rest of us. To this group, the aloofness of science is a smoke screen behind which the inevitable emotions and ideologies hide.
  • At least in science, Strevens tells us, “the appearance of objectivity” has turned out to be “as important as the real thing.”
  • The subjectivists are right, he admits, inasmuch as scientists are regular people with a “need to win” and a “determination to come out on top.”
  • But they are wrong to think that subjectivity compromises the scientific enterprise. On the contrary, once subjectivity is channelled by the iron rule, it becomes a vital component of the knowledge machine. It’s this redirected subjectivity—to come out on top, you must follow the iron rule!—that solves science’s “problem of motivation,” giving scientists no choice but “to pursue a single experiment relentlessly, to the last measurable digit, when that digit might be quite meaningless.”
  • If it really was a speech code that instigated “the extraordinary attention to process and detail that makes science the supreme discriminator and destroyer of false ideas,” then the peculiar rigidity of scientific writing—Strevens describes it as “sterilized”—isn’t a symptom of the scientific mind-set but its cause.
  • The iron rule—“a kind of speech code”—simply created a new way of communicating, and it’s this new way of communicating that created science.
  • Other theorists have explained science by charting a sweeping revolution in the human mind; inevitably, they’ve become mired in a long-running debate about how objective scientists really are
  • In “The Knowledge Machine: How Irrationality Created Modern Science” (Liveright), Michael Strevens, a philosopher at New York University, aims to identify that special something. Strevens is a philosopher of science
  • Compared with the theories proposed by Popper and Kuhn, Strevens’s rule can feel obvious and underpowered. That’s because it isn’t intellectual but procedural. “The iron rule is focused not on what scientists think,” he writes, “but on what arguments they can make in their official communications.”
  • Like everybody else, scientists view questions through the lenses of taste, personality, affiliation, and experience
  • geologists had a professional obligation to take sides. Europeans, Strevens reports, tended to back Wegener, who was German, while scholars in the United States often preferred Simpson, who was American. Outsiders to the field were often more receptive to the concept of continental drift than established scientists, who considered its incompleteness a fatal flaw.
  • Strevens’s point isn’t that these scientists were doing anything wrong. If they had biases and perspectives, he writes, “that’s how human thinking works.”
  • Eddington’s observations were expected to either confirm or falsify Einstein’s theory of general relativity, which predicted that the sun’s gravity would bend the path of light, subtly shifting the stellar pattern. For reasons having to do with weather and equipment, the evidence collected by Eddington—and by his colleague Frank Dyson, who had taken similar photographs in Sobral, Brazil—was inconclusive; some of their images were blurry, and so failed to resolve the matter definitively.
  • it was only natural for intelligent people who were free of the rule’s strictures to attempt a kind of holistic, systematic inquiry that was, in many ways, more demanding. It never occurred to them to ask if they might illuminate more collectively by thinking about less individually.
  • In the single-sphered, pre-scientific world, thinkers tended to inquire into everything at once. Often, they arrived at conclusions about nature that were fascinating, visionary, and wrong.
  • How Does Science Really Work?Science is objective. Scientists are not. Can an “iron rule” explain how they’ve changed the world anyway?By Joshua RothmanSeptember 28, 2020
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The Lasting Lessons of John Conway's Game of Life - The New York Times - 0 views

  • “Because of its analogies with the rise, fall and alterations of a society of living organisms, it belongs to a growing class of what are called ‘simulation games,’” Mr. Gardner wrote when he introduced Life to the world 50 years ago with his October 1970 column.
  • The Game of Life motivated the use of cellular automata in the rich field of complexity science, with simulations modeling everything from ants to traffic, clouds to galaxies. More trivially, the game attracted a cult of “Lifenthusiasts,” programmers who spent a lot of time hacking Life — that is, constructing patterns in hopes of spotting new Life-forms.
  • The tree of Life also includes oscillators, such as the blinker, and spaceships of various sizes (the glider being the smallest).
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  • Patterns that didn’t change one generation to the next, Dr. Conway called still lifes — such as the four-celled block, the six-celled beehive or the eight-celled pond. Patterns that took a long time to stabilize, he called methuselahs.
  • The second thing Life shows us is something that Darwin hit upon when he was looking at Life, the organic version. Complexity arises from simplicity!
  • I first encountered Life at the Exploratorium in San Francisco in 1978. I was hooked immediately by the thing that has always hooked me — watching complexity arise out of simplicity.
  • Life shows you two things. The first is sensitivity to initial conditions. A tiny change in the rules can produce a huge difference in the output, ranging from complete destruction (no dots) through stasis (a frozen pattern) to patterns that keep changing as they unfold.
  • Life shows us complex virtual “organisms” arising out of the interaction of a few simple rules — so goodbye “Intelligent Design.”
  • I’ve wondered for decades what one could learn from all that Life hacking. I recently realized it’s a great place to try to develop “meta-engineering” — to see if there are general principles that govern the advance of engineering and help us predict the overall future trajectory of technology.
  • Melanie Mitchell— Professor of complexity, Santa Fe Institute
  • Given that Conway’s proof that the Game of Life can be made to simulate a Universal Computer — that is, it could be “programmed” to carry out any computation that a traditional computer can do — the extremely simple rules can give rise to the most complex and most unpredictable behavior possible. This means that there are certain properties of the Game of Life that can never be predicted, even in principle!
  • I use the Game of Life to make vivid for my students the ideas of determinism, higher-order patterns and information. One of its great features is that nothing is hidden; there are no black boxes in Life, so you know from the outset that anything that you can get to happen in the Life world is completely unmysterious and explicable in terms of a very large number of simple steps by small items.
  • In Thomas Pynchon’s novel “Gravity’s Rainbow,” a character says, “But you had taken on a greater and more harmful illusion. The illusion of control. That A could do B. But that was false. Completely. No one can do. Things only happen.”This is compelling but wrong, and Life is a great way of showing this.
  • In Life, we might say, things only happen at the pixel level; nothing controls anything, nothing does anything. But that doesn’t mean that there is no such thing as action, as control; it means that these are higher-level phenomena composed (entirely, with no magic) from things that only happen.
  • Stephen Wolfram— Scientist and C.E.O., Wolfram Research
  • Brian Eno— Musician, London
  • Bert Chan— Artificial-life researcher and creator of the continuous cellular automaton “Lenia,” Hong Kong
  • it did have a big impact on beginner programmers, like me in the 90s, giving them a sense of wonder and a kind of confidence that some easy-to-code math models can produce complex and beautiful results. It’s like a starter kit for future software engineers and hackers, together with Mandelbrot Set, Lorenz Attractor, et cetera.
  • if we think about our everyday life, about corporations and governments, the cultural and technical infrastructures humans built for thousands of years, they are not unlike the incredible machines that are engineered in Life.
  • In normal times, they are stable and we can keep building stuff one component upon another, but in harder times like this pandemic or a new Cold War, we need something that is more resilient and can prepare for the unpreparable. That would need changes in our “rules of life,” which we take for granted.
  • Rudy Rucker— Mathematician and author of “Ware Tetralogy,” Los Gatos, Calif.
  • That’s what chaos is about. The Game of Life, or a kinky dynamical system like a pair of pendulums, or a candle flame, or an ocean wave, or the growth of a plant — they aren’t readily predictable. But they are not random. They do obey laws, and there are certain kinds of patterns — chaotic attractors — that they tend to produce. But again, unpredictable is not random. An important and subtle distinction which changed my whole view of the world.
  • William Poundstone— Author of “The Recursive Universe: Cosmic Complexity and the Limits of Scientific Knowledge,” Los Angeles, Calif.
  • The Game of Life’s pulsing, pyrotechnic constellations are classic examples of emergent phenomena, introduced decades before that adjective became a buzzword.
  • Fifty years later, the misfortunes of 2020 are the stuff of memes. The biggest challenges facing us today are emergent: viruses leaping from species to species; the abrupt onset of wildfires and tropical storms as a consequence of a small rise in temperature; economies in which billions of free transactions lead to staggering concentrations of wealth; an internet that becomes more fraught with hazard each year
  • Looming behind it all is our collective vision of an artificial intelligence-fueled future that is certain to come with surprises, not all of them pleasant.
  • The name Conway chose — the Game of Life — frames his invention as a metaphor. But I’m not sure that even he anticipated how relevant Life would become, and that in 50 years we’d all be playing an emergent game of life and death.
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Experts Describe the Perfect Classroom Space for Learning in School - The Atlantic - 0 views

  • The seats, space, and stuff that idyllic learning environments are made of
  • We asked prominent voices in education—from policy makers and teachers to activists and parents—to look beyond laws, politics, and funding and imagine a utopian system of learning. They went back to the drawing board—and the chalkboard—to build an educational Garden of Eden.
  • Students need to be in classrooms that inspire them—spaces that are light, airy, and filled with examples of work that they aspire to do
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  • There might be desks, cushions, or benches arranged in rows or circles—however the teachers want them, as not every classroom will follow a template. Each classroom will be set up based on what is necessary to meet learning objectives. But schools will prioritize configuring classes to inspire learning first and foremost, and, where appropriate, reflect the diversity of environments that students are exposed to outside a school setting.
  • Students will have beautiful spaces that make them feel good to be at school—with art, living plants, music where appropriate, comfortable seating, and fast internet access.
  • Windows that open are a nice feature, as are clean bathrooms and individual desks that can be rearranged
  • Smaller schools and smaller rooms seem to work better than larger schools and larger rooms.  
  • My experience as a high-school principal taught me to never spend too much time worrying about the “small stuff.”
  • There will be a large open space that will serve as a community gathering spot. The classroom will have big windows to let a lot of natural light shine through. The room will be colorful without being obnoxious—colors will be blues, greens, whites, and yellows.
  • There will be areas where students can post ideas to help make the learning environment more engaging and fun. The classroom will also be tailored to the topic, but all will have interactive stations where hands-on learning can be experienced by all students.
  • In the future, we won’t have “classrooms.” The enemy of the future of the classroom has arguably been that phrase: “the future of the classroom.” It locks us into a model of believing students will be sorted by age and sit in a room together with one teacher in the front.
  • Form will follow function, and if one of the key principles of public education is to instill an appreciation for democracy, then classrooms will be arranged so that students are equals with one another
  • (not some in the front, others in the back), and so that students are active participants in learning, not passive recipients of teachers’ knowledge.
  • Whereas the traditional lecture hall connotes hierarchy, placing desks in a circle suggests students should be learning to debate and become decision makers. Within the circle, desks will also be clustered in small groups of four to encourage collaboration among students.
  • High-school classrooms will be designed by students themselves, providing breakout space for group work and more private areas for individual work and studying. High-school classrooms will reflect the transition that students are facing, allowing for independence but also providing a nurturing environment for curiosity.
  • It’s also important to look at the appropriate role of technology in the classroom. Technology can be a powerful tool, but it must be implemented with the intention of enhancing educator-facilitated learning, not replacing i
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    A few voices describe their visions of the best types of schools- what environment would our brains thrive in best?
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Oliver Sacks's New Book Asks: What Is the Mind? - 0 views

  • If people perceive time in varying ways, for instance, what does that say about time itself? If we misremember the past, he wonders, what else might we be wrong about? If creativity is largely a subconscious phenomenon, what else might be happening to us without our knowing?
  • he posits that “minds” might not belong solely to humans and animals. “Plants ‘know’ what to do, and they ‘remember,’” he writes, while “the tiny, stalked, trumpet-shaped unicellular organism Stentor employs a repertoire of at least five different responses to being touched.” Is the ability to respond to stimuli, he wonders, a sign of a mind?
  • “When I am writing, thoughts seem to organize themselves in spontaneous succession and to clothe themselves instantly in appropriate words. I feel I can bypass or transcend much of my own personality, my neuroses. It is at once not me and the innermost part of me.”
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  • Sacks is, at heart, a philosopher. But he is a philosopher looking not for answers but for increasingly grander questions.
  • It is only the wisest among us who search not only for answers but also for questions.
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GE Power, in Need of a Lift, Chases Tesla and Siemens in Batteries - WSJ - 0 views

  • The giant platform called GE Reservoir is expected to store electricity generated by wind turbines and solar panels for later use. The battery-storage market is expected to grow in coming years as some utilities look for less-expensive alternatives to the power plants that fire up during peak hours to meet power demand.
  • Siemens, one of GE’s biggest rivals in the power business, paired with AES Corp. last year to launch Fluence Energy LLC, a joint venture that is building what is expected to be the world’s largest lithium-ion battery in California. IHS Markit predicts the global market for batteries in the power sector will grow 14% annually through 2025.
  • The company tried making batteries using sodium-based technologie
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  • Success would be a needed boost for the struggling conglomerate, which is in the middle of restructuring and said last week it would overhaul its board. GE is seeking access to a market that Navigant Research predicts will generate tens of billions of dollars in revenue in the next decade or so.
  • Prices of lithium-ion batteries have dropped sharply in recent years, as they have become ubiquitous in products such as laptops and smartphones, improving the economies of scale of manufacturing. That is start
  • GE is hoping to change that with the Reservoir platform. GE says the Reservoir battery can last about 15% longer than the best batteries currently on the market and can be installed quicker.
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From Climate Change to Omnicide - Tablet Magazine - 0 views

  • As this decade dawns, we are confronted with the reality of climate crisis—both in the image of uncontainable fires raging across the Australian bush, and in the voices of young people speaking truth to power and calling out for their future and the living Earth.
  • And as this future has arrived with smoke-filled air, its vocabulary has evolved: from the innocuous sounding “climate change,” to “climate crisis,” and now “climate collapse,” gradually awakening us to an accelerating disaster. Our seas polluted with plastic, air toxic, trees burning whether in the Amazon or Australia, we are also including other words to describe the nature of this crisis: ecocide, our deliberate destruction of the natural environment; and most recently: omnicide. Omnicide images a crime “we have previously been unable to witness because we have never imagined it.” Across Australia—with billions of dead animals and birds, and millions of people suffering ill health effects—we are witnessing what the world will look like with three or more degrees warming, “the killing of everything.”
  • With almost a hundred homes destroyed, we waited in the smoke-filled air, just out of the mandatory evacuation zone, with our go-bags ready, for nearly a week without electricity.
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  • This insecurity, anxiety, is especially affecting young people, who rightly fear for their future, fear that the current system is pushing the Earth beyond its ecological limits.
  • Understandably we try to place the future of climate crisis within the images of our present conditions—that this way of life will continue, saved by technological solutions or planting millions of trees.
  • While this vast devastation unfolds across Australia, its politicians—paid by climate deniers—are in the process of developing a huge new open coal mine helped by Siemens, which also profited from the Holocaust as a leading corporate participant in Hitler’s “death through work program,” despite the protests of Fridays for Future activists;
  • What will our world look like two, or three degrees warmer? We can already see signs of a future few of us want to imagine.
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This Strange Microbe May Mark One of Life's Great Leaps - The New York Times - 0 views

  • A bizarre tentacled microbe discovered on the floor of the Pacific Ocean may help explain the origins of complex life on this planet and solve one of the deepest mysteries in biology, scientists reported on Wednesday.Two billion years ago, simple cells gave rise to far more complex cells. Biologists have struggled for decades to learn how it happened.
  • The new species, called Prometheoarchaeum, turns out to be just such a transitional form, helping to explain the origins of all animals, plants, fungi — and, of course, humans. The research was reported in the journal Nature.
  • Species that share these complex cells are known as eukaryotes, and they all descend from a common ancestor that lived an estimated two billion years ago.Before then, the world was home only to bacteria and a group of small, simple organisms called archaea. Bacteria and archaea have no nuclei, lysosomes, mitochondria or skeletons
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  • In the late 1900s, researchers discovered that mitochondria were free-living bacteria at some point in the past. Somehow they were drawn inside another cell, providing new fuel for their host. In 2015, Thijs Ettema of Uppsala University in Sweden and his colleagues discovered fragments of DNA in sediments retrieved from the Arctic Ocean. The fragments contained genes from a species of archaea that seemed to be closely related to eukaryotes.Dr. Ettema and his colleagues named them Asgard archaea. (Asgard is the home of the Norse gods.) DNA from these mystery microbes turned up in a river in North Carolina, hot springs in New Zealand and other places around the world.
  • Masaru K. Nobu, a microbiologist at the National Institute of Advanced Industrial Science and Technology in Tsukuba, Japan, and his colleagues managed to grow these organisms in a lab. The effort took more than a decade.The microbes, which are adapted to life in the cold seafloor, have a slow-motion existence. Prometheoarchaeum can take as long as 25 days to divide. By contrast, E. coli divides once every 20 minutes.
  • In the lab, the researchers mimicked the conditions in the seafloor by putting the sediment in a chamber without any oxygen. They pumped in methane and extracted deadly waste gases that might kill the resident microbes.The mud contained many kinds of microbes. But by 2015, the researchers had isolated an intriguing new species of archaea. And when Dr. Ettema and colleagues announced the discovery of Asgard archaea DNA, the Japanese researchers were shocked. Their new, living microbe belonged to that group.The researchers then undertook more painstaking research to understand the new species and link it to the evolution of eukaryotes.The researchers named the microbe Prometheoarchaeum syntrophicum, in honor of Prometheus, the Greek god who gave humans fire — after fashioning them from clay.
  • This finding suggests that the proteins that eukaryotes used to build complex cells started out doing other things, and only later were assigned new jobs.Dr. Nobu and his colleagues are now trying to figure out what those original jobs were. It’s possible, he said, that Prometheoarchaeum creates its tentacles with genes later used by eukaryotes to build cellular skeletons.
  • Before the discovery of Prometheoarchaeum, some researchers suspected that the ancestors of eukaryotes lived as predators, swallowing up smaller microbes. They might have engulfed the first mitochondria this way.
  • Instead of hunting prey, Prometheoarchaeum seems to make its living by slurping up fragments of proteins floating by. Its partners feed on its waste. They, in turn, provide Prometheoarchaeum with vitamins and other essential compounds.
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How the Father of Computer Science Decoded Nature's Mysterious Patterns - The New York ... - 0 views

  • few have heard of Turing, the naturalist who explained patterns in nature with math
  • And even now, scientists are finding new insights from Turing’s legacy.
  • A keen natural observer since childhood, Turing noticed that many plants contained clues that math might be involved.
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  • It’s unclear why this interested the early computer scientist, but Turing had told a friend that he wanted to defeat Argument From Design, the idea that for complex patterns to exist in nature, something supernatural, like God, had to create them.
  • He just thought mathematics was very powerful, and you could use it to explain lots and lots of things — and you should try
  • By creating three-dimensional Turing patterns like bubbles and tubes in membranes, the researchers increased their permeability, creating filters that could better separate salt from water than traditional ones.
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We Went to the Moon. Why Can't We Solve Climate Change? - The New York Times - 0 views

  • Fifty years after humans first left bootprints in the lunar dust, it’s an enticing idea. The effort and the commitment of brainpower and money, and the glorious achievement itself, shine as an international example of what people can do when they set their minds to it. The spinoff technologies ended up affecting all of our lives.So why not do it all over again — but instead of going to another astronomical body and planting a flag, why not save our own planet?
  • But President Kennedy did not have to convince people that the moon existed. In our current political climate, the clear evidence that humans have generated greenhouse gases that are having a powerful effect on climate, and will have a greater effect into the future, has not moved the federal government to act with vigor. And a determined faction even argues that climate change is a hoax, as President Donald Trump has falsely stated at various times.
  • The task of reversing that accumulation of greenhouse gases is vast, and progress is painfully slow.
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  • Climate presents more complicated issues than getting to the moon did, said John M. Logsdon, historian of the space program and founder of the Space Policy Institute at George Washington University.
  • “The Decision to Go to the Moon,” that laid out four conditions that made Apollo possible. In the case of the space program, the stimulus was the first human spaceflight of the Russian cosmonaut Yuri A. Gagarin, which filled Americans with dread of losing the space race. In an interview, Dr. Logsdon said it has to be “a singular act that would force action, that you couldn’t ignore.”
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Inherited Learning? It Happens, but How Is Uncertain | Quanta Magazine - 0 views

  • Most recently, some researchers have found evidence that even some learned behaviors and physiological responses can be epigenetically inherited.
  • But in the 1950s, the botanist Royal Alexander Brink discovered that, under different environmental conditions, maize plants with identical genomes expressed different-colored kernels, and these colors were heritable. It was some of the first evidence for epigenetic inheritance. Since then, more examples of inheritance without a clear genetic basis have come to light, as have a variety of possible mechanisms for epigenetic inheritance.
  • C. elegans worms infected with viruses would defend themselves by generating small RNAs that targeted and neutralized the viruses. Moreover, the subsequent offspring of the roundworms also made these small protective RNAs, even though they had never been exposed to the viruses.
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  • He hypothesizes that the process involves one or more molecules released by the nervous system — perhaps small RNAs, perhaps something secreted like a hormone. But somehow those germ cells then influence the behavior of the next generation and seem to circumvent the normal need for rde-4 in the production of the small RNAs for chemotaxis in the progeny.
  • “I believe that today, there is not a single solid paper showing that only small RNAs are involved in epigenetic inheritance,” said Isabelle Mansuy, a neuroepigenetics researcher at the Swiss Federal Institute of Technology Zurich and the University of Zurich who studies the inheritance of trauma in humans and mice. In the mouse model she works with, she knows that small RNAs are not sufficient because if she injects small RNAs alone into fertilized mouse eggs, the resulting animals do not show the RNA-associated trait.
  • “If we can ingest a chemical from our environment that changes the epigenomes of the egg or sperm, why couldn’t our brain make a similar molecule that does the same thing?”
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1.5 degrees Celsius: the sad truth about our boldest climate change target - Vox - 0 views

  • the countries participating in the United Nations Framework Convention on Climate Change (UNFCCC) agreed to a common target: to hold the rise in global average temperature “well below 2 degrees Celsius above pre-industrial levels and to pursue efforts to limit the temperature increase even further to 1.5 degrees Celsius.” The lower end of that range, 1.5˚C, has become a cause célèbre among climate activists.
  • If we had peaked and begun steadily reducing emissions 20 years ago, the necessary pace of reductions would have been around 3 percent a year, which is ... well, “realistic” is too strong — it still would have required rapid, coordinated action of a kind never seen before in human history — but it was at least possible to envision.
  • it is not the job of those of us in the business of observation and analysis to make the public feel or do things. That’s what activists do.
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  • Now, to hit 1.5˚C, emissions would need to fall off a cliff, falling by 15 percent a year every year, starting in 2020, until they hit net zero.
  • Emissions have never fallen at 15 percent annually anywhere, much less everywhere. And what earthly reason do we have to believe that emissions will start plunging this year? Look around! The democratic world is in the grips of a populist authoritarian backlash that shows no sign of resolving itself any time soon
  • In short, there is no “safe” level of global warming
  • All of those impacts become much worse at 2˚C. (The World Resources Institute has a handy chart; see also this graphic from Carbon Brief.) Severe heat events will become 2.6 times worse, plant and vertebrate species loss 2 times worse, insect species loss 3 times worse, and decline in marine fisheries 2 times worse. Rather than 70 to 90 percent of coral reefs dying, 99 percent will die. Many vulnerable and low-lying areas will become uninhabitable and refugee flows will radically increase. And so on. At 2˚C, climate change will be devastating for large swathes of the globe.
  • We’ve waited too long. Practically speaking, we are heading past 1.5˚C as we speak and probably past 2˚C as well.
  • To really grapple with climate change, we have to understand it, and more than that, take it on board emotionally
  • Given the scale of the challenge and the compressed time to act, there is effectively no practical danger of anyone, at any level, doing too much or acting too quickly.
  • Right now, much of Australia is on fire — half a billion animals have likely died since September — and it is barely breaking the news cycle in the US
  • I can’t help but think that the first step in defending and expanding that empathy is reckoning squarely with how much damage we’ve already done and are likely to do, working through the guilt and grief, and resolving to minimize the suffering to come.
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Less pollution over the US as coronavirus shuts down public places, satellite images sh... - 0 views

  • Images taken over the first three weeks of March show less nitrogen dioxide over parts of the United States than the same time last year. Nitrogen dioxide in the air comes primarily from the burning of fuel and forms from the emissions of cars, trucks, buses, power plants and off-road equipment, according to the US Environmental Protection Agency.
  • Satellite images released by NASA and the European Space Agency also show a dramatic reduction in nitrogen dioxide emissions in China as the nation implemented drastic coronavirus restrictions.
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Lawmakers around the nation are proposing bills for -- and against -- vaccinations - CNN - 0 views

  • At a time when almost everything is politicized, vaccination has planted itself squarely on the national stage.
  • On one side of the debate are parents who are rebelling against settled science and calling on states to broaden vaccine exemptions. They cite their faith or believe vaccines pose danger to their children, even though no major religion opposes them and claims of vaccines' link to autism has been long debunked.
  • "I won't be surprised if we see many pro-vaccine bills this year," said Dr. Sean O'Leary, a member of the American Academy of Pediatrics Committee on Infectious Diseases. "The measles outbreaks were really a wake-up call, showing legislators that maintaining high vaccination rates is not just a theoretical goal."
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  • An overwhelming majority of American adults (88%) say the benefits of the measles, mumps and rubella (MMR) vaccine outweigh the risks, according to a new Pew Research Center survey.And last year, 14 states proposed eliminating religious exemptions for vaccines -- a marked increase from years past, according to the American Academy of Pediatrics.
  • "When you choose not to vaccinate, you're putting your child at risk of disease, but you're also putting other people at risk," O'Leary said.
  • "We need to have the ability in our country, if we find a commercial pharmaceutical product is not as safe and effective as we're being told it is, we should have the right to make informed consent to use the product," she said.
  • "Science is really on the side of vaccinations," said O'Leary, who is an associate professor of pediatrics at the University of Colorado School of Medicine. "They're one of the best public health interventions in history in terms of the numbers of lives saved. The benefits far outweigh the risk."
  • "When vaccination rates fall, we see disease, and people suffer. Protecting children in schools is a worthy goal of government, regardless of political affiliation," he said. "There's really no good reason to exempt your child from vaccination -- only medical."
  • New York, California and Washington state took action after massive measles outbreaks in 2019, a year that saw the highest reported measles cases since the disease was declared eliminated nationwide in 2000.
  • Many of the religious exemption laws are not new. Several states first passed them in the 1960s and 1970s, thanks to an influx of lobbyists from the Christian Science Church, which doesn't ban members from using vaccines but encourages healing through prayer.
  • Supporters of vaccine exemptions see laws like those passed in New York and Washington as "fundamentally a threat to their ability to make informed consent about vaccinations," said Fisher, president of the National Vaccine Information Center.
  • Proponents on both sides of the debate have found allies across the political spectrum. Republican lawmakers have sponsored stricter bills, and Democratic governors have drawn the line at mandating vaccines.
  • "It's a tough balance, but you're using a public -- and private -- resource in conjunction with lots of other kids," Harris told CNN. "There are other venues where they can be educated, they can still have their freedom, but they're not going into a public school and spread their disease."
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Google searches for CBD expected to hit record high this year - ABC News - 0 views

  • Nationwide, searches for CBD outstripped queries for other popular health topics, like veganism, vaccination and marijuana.
  • Clearly there's a demand for information, but details about the product itself is frustratingly limited. CBD, which is derived from cannabis plants, isn't psychoactive, meaning unlike the other well-known ingredient in marijuana, tetrahydrocannabinol (THC), it doesn't get you high.
  • "When people are allowed to market CBD by saying anything, is it surprising that demand for it is so high?" Ayers asked.
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Opinion | Standard metrics won't suffice. Here's how to measure Trump's failures so the... - 0 views

  • Maybe what’s needed are different units for measuring the Trump administration’s failures and scandals, since the standard metrics aren’t registering. His record should be quantified in scales that a Fox News viewer might be more familiar with: not body counts or dollars, but Benghazis and Solyndras.
  • For instance, sometimes pundits try to put the 183,000 covid-19 deaths in context by noting that cumulative deaths per capita in the United States are double those of Canada, quintuple those of Germany, 20 times those of Australia, 90 times those of South Korea, and so on.
  • here’s a different way to contextualize this national trauma: The number of lives lost to covid-19 is roughly equal to the death toll of 60 9/11 attacks.
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  • Last week alone, though, 1.6 million people newly applied for unemployment benefits. That’s the equivalent of 2,300 Carrier plants
  • Somehow, for years, the four tragic deaths in Benghazi consumed the agenda of six GOP-controlled congressional committees and the programming of the most-watched cable news channel. But today, a deadly shock magnified by government ineptitude that has led to 46,000 times as many lives lost “is what it is.”
  • the coronavirus death toll is about 46,000 Benghazis
  • According to congressional investigators, Navarro negotiated a contract that resulted in the government overpaying for ventilators by $500 million. (The contract was canceled Monday.) He also championed a $765 million federal loan to Eastman Kodak to transform it into a drugmaker. (The loan has since unraveled and is the subject of a securities investigation.)
  • So how many taxpayer dollars was Navarro involved in wasting through these two deals alone? Measured in units that should be familiar to consumers of right-wing news, it’s roughly two Solyndras.
  • The debt increase under Trump during a single term is on track to surpass that under Obama across two terms.
  • For each Hillary Clinton private email scandal (one), there are at least eight senior Trump officials who have reportedly used private email to conduct official business
  • For every Obama-era incident involving supposed retaliation against political opponents, there are literally dozens of instances of Trump trying to use the power of his office to punish perceived enemie
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How to Talk About Climate Change Across the Political Divide | The New Yorker - 0 views

  • “It was really moving to Texas that set me on this path of figuring out how to communicate about climate change,” she told me. “I was the only climate scientist within two hundred miles.”
  • She records the questions she is asked afterward, using an app, and the two most frequent are: “What gives you hope?” and “How do I talk to my [blank] about climate change?
  • In the late nineties, a Gallup poll found that forty-six per cent of Democrats and forty-seven per cent of Republicans agreed that the effects of global warming had already begun.
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  • In her new book, “Saving Us,” which comes out in September, Hayhoe sets out to answer these questions. Chapter by chapter, she lays out effective strategies for communicating about the urgency of climate change across America’s political divide.
  • She breaks out categories—originally defined by her colleague Anthony Leiserowitz, at the Yale Program on Climate Change Communication, and other researchers—of attitudes toward global warming: alarmed, concerned, cautious, disengaged, and doubtful. Only the remaining eight per cent of Americans fall into the final category, dismissive.
  • In the past decade, though, as the scope of the crisis became clear, Democrats began pressing for policies to cut U.S. reliance on fossil fuels, and Republicans were reluctant to commit. Energy companies stepped into the stalemate and began aggressively lobbying politicians, and injecting doubt into the public discourse, to stop such policies from taking effect. “Industry swung into motion to activate the political system in their favor,” Hayhoe said.
  • “In a study of fifty-six countries, researchers found people’s opinions on climate change to be most strongly correlated not with education and knowledge, but rather with ‘values, ideologies, worldviews and political orientation,’ ”
  • One salient problem is an aspect of human behavior that researchers have termed “solution aversion.” Solving the climate crisis will require ending our reliance on fossil fuels, which people believe would involve major sacrifice.
  • “If there’s a problem and we’re not going to fix it, then that makes us bad people,” Hayhoe said. “No one wants to be a bad person.” So instead people are happy to seize on excuses not to take action.
  • Most are what she calls “science-y sounding objections, and, in the U.S., religious-y sounding objections.”
  • Hayhoe often hears that the Earth has always heated and cooled according to its own intrinsic cycle, or that God, not humanity, controls the fate of the planet. These objections can then harden into aspects of our political identity.
  • Hayhoe eschews the term “climate denier,” saying that she has “seen it applied all too often to shut down discussion rather than encourage it.”
  • So much of this is not about the facts,” Leiserowitz told me later. “It’s about trusting the person the facts come from.”
  • research has shown her that dismissives are nearly impossible to influence. They are also few enough that it should be possible to build political will around fighting climate change by focussing on others.
  • “It’s not about the loudest voices,” Hayhoe told me. “It’s about everyone else who doesn’t understand why climate change matters or what they can do about it.”
  • Leiserowitz told me. His work has revealed, for example, that conversations about the climate tend to be more effective if both speakers share a core value or an aspect of their identity. The most effective climate communicators to conservatives are often people of faith, members of the military, and Republicans who are nevertheless committed to the climate.
  • “That’s why it’s so important to seek out like-minded groups: winter athletes, parents, fellow birders or Rotarians, or people who share our faith.”
  • There is a long history within evangelicalism of advocating “creation care,” the belief that God charged humanity with caring for the earth. The Evangelical Environmental Network, which Hayhoe advises, argues that evangelicals should follow a “Biblical mandate to care for creation,”
  • Hayhoe believes that emphasizing the care of plants and animals is less effective than highlighting the potential dangers for our fellow human beings. “It’s not about saving the planet—it’s about saving us,”
  • One of her communication strategies is to talk to people about their own observations, which help them connect the realities of their lives to the abstraction of climate change.
  • With farmers, Hayhoe avoids using the term “climate change,” since the phenomenon is frequently seen as a liberal hoax. “We use the words ‘climate variability’ and ‘long-term trends,’ ” she said.
  • Scott’s work served another purpose. By showing success with his climate-conscious farming techniques, he might persuade other farmers to join in, potentially becoming the center of what Hayhoe calls a cluster. “I preach to my friends about how well it’s doing,” he said.
  • I don’t accost people in diners,” she wrote me, later. “I wait until they come to me.”
  • “As recently as 2008, former speaker of the house Newt Gingrich, a Republican, and current House speaker Nancy Pelosi, a Democrat, cozied up on a love seat in front of the U.S. Capitol to film a commercial about climate change,”
  • She then directed the conversation to Republican-led free market initiatives to combat climate change by putting a price on carbon emissions. Companies passed their costs onto the rest of us by putting the carbon into the atmosphere, she told Dale, “but what if they had to pay for it? What if, when someone’s house burned down because of a forest fire, the companies making money from selling carbon had to pay a homeowner back?” Dale responded, “Well, I’m in favor of that.”
  • “It’s so important to educate kids about what’s going on, not to frighten them but to show them they can have a hand in solutions.”
  • Through the years, she’s developed a system to manage trolls. “It’s been trial and error, error, error,” she said. She now responds once, offering a link to resources.
  • Most fire back with gendered insults, often plays on her last name, after which she blocks the sender.
  • ayhoe doesn’t urge guilt on her listeners. She only urges that we change our trajectory. “That’s all repentance means,” she said. “To turn.”
  • the most important aspect of fighting climate change is pushing for policies that will cut our reliance on fossil fuels. She urges the alarmed to get involved in politics, beginning with lobbying politicians at the local and state level.
  • she’d come across a book, “Scientists as Prophets: A Rhetorical Genealogy,” that examined the role of prophets in society, beginning with the oracle at Delphi, stretching through the Old Testament, and culminating in the work of modern-day scientists.
  • Studies show that early adopters help shift the norms of their communities.
  • By Eliza GriswoldSeptember 16, 2021
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Book review - The Dawn of Everything: A New History of Humanity | The Inquisitive Biolo... - 0 views

  • Every few years, it seems, there is a new bestselling Big History book. And not infrequently, they have rather grandiose titles.
  • , I hope to convince you why I think this book will stand the test of time better.
  • First, rather than one author’s pet theory, The Dawn of Everything is the brainchild of two outspoken writers: anthropologist David Graeber (a figurehead in the Occupy Wall Street movement and author of e.g. Bullshit Jobs) and archaeologist David Wengrow (author of e.g. What Makes Civilization?). I expect a large part of their decade-long collaboration consisted of shooting holes in each other’s arguments
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  • Colonisation exposed us to new ideas that shocked and confused us. Graeber & Wengrow focus on the French coming into contact with Native Americans in Canada, and in particular on Wendat Confederacy philosopher–statesman Kandiaronk as an example of European traders, missionaries, and intellectuals debating with, and being criticized by indigenous people. Historians have downplayed how much these encounters shaped Enlightenment ideas.
  • this thought-provoking book is armed to the teeth with fascinating ideas and interpretations that go against mainstream thinking
  • ather than yet another history book telling you how humanity got here, they take their respective disciplines to task for dealing in myths.
  • Its legacy, shaped via several iterations, is the modern textbook narrative: hunter-gathering was replaced by pastoralism and then farming; the agricultural revolution resulted in larger populations producing material surpluses; these allowed for specialist occupations but also needed bureaucracies to share and administer them to everyone; and this top-down control led to today’s nation states. Ta-daa!
  • this simplistic tale of progress ignores and downplays that there was nothing linear or inevitable about where we have ended up.
  • ake agriculture. Rather than humans enthusiastically entering into what Harari in Sapiens called a Faustian bargain with crops, there were many pathways and responses
  • Experiments show that plant domestication could have been achieved in as little as 20–30 years, so the fact that cereal domestication here took some 3,000 years questions the notion of an agricultural “revolution”. Lastly, this book includes many examples of areas where agriculture was purposefully rejected. Designating such times and places as “pre-agricultural” is misleading, write the authors, they were anti-agricultural.
  • The idea that agriculture led to large states similarly needs revision
  • correlation is not causation, and some 15–20 additional centres of domestication have since been identified that followed different paths. Some cities have previously remained hidden in the sediments of ancient river deltas until revealed by modern remote-sensing technology.
  • “extensive agriculture may thus have been an outcome, not a cause, of urbanization”
  • And cities did not automatically imply social stratification. The Dawn of Everything fascinates with its numerous examples of large settlements without ruling classes, such as Ukrainian mega-sites, the Harappan civilization, or Mexican city-states.
  • These instead relied on collective decision-making through assemblies or councils, which questions some of the assumptions of evolutionary psychology about scale: that larger human groups require complex (i.e. hierarchical) systems to organize them.
  • e what is staring them in the face
  • humans have always been very capable of consciously experimenting with different social arrangements. And—this is rarely acknowledged—they did so on a seasonal basis, spending e.g. part of the year settled in large communal groups under a leader, and another part as small, independently roving bands.
  • Throughout, Graeber & Wengrow convincingly argue that the only thing we can say about our ancestors is that “there is no single pattern. The only consistent phenomenon is the very fact of alteration […] If human beings, through most of our history, have moved back and forth fluidly between different social arrangements […] maybe the real question should be ‘how did we get stuck?
  • Next to criticism, the authors put out some interesting ideas of their own, of which I want to quickly highlight two.
  • The first is that some of the observed variations in social arrangements resulted from schismogenesis. Anthropologist Gregory Bateson coined this term in the 1930s to describe how people define themselves against or in opposition to others, adopting behaviours and attitudes that are different.
  • The second idea is that states can be described in terms of three elementary forms of domination: control of violence, control of information, and individual charisma, which express themselves as sovereignty, administration, and competitive politics.
  • Our current states combine these three, and thus we have state-endorsed violence in the form of law enforcement and armies, bureaucracy, and the popularity contests we call elections in some countries, and monarchs, oligarchs, or tyrants in other countries. But looking at history, there is no reason why this should be and the authors provide examples of societies that showed only one or two such forms of control
  • Asking which past society most resembles today’s is the wrong question to ask. It risks slipping into an exercise in retrofitting, “which makes us scour the ancient world for embryonic versions of our modern nation states”
  • I have left unmentioned several other topics: the overlooked role of women, the legacy of Rousseau’s and Hobbes’s ideas, the origins of inequality and the flawed assumptions hiding behind that question
  • There are so many historical details and delights hiding between these covers that I was thoroughly enthralle
  • If you have any interest in big history, archaeology, or anthropology, this book is indispensable. I am confident that the questions and critiques raised here will remain relevant for a long time to come.
  • I was particularly impressed by the in-depth critique by worbsintowords on his YouTube channel What is Politics? of (so far) five videos
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How a dose of MDMA transformed a white supremacist - BBC Future - 0 views

  • February 2020, Harriet de Wit, a professor of psychiatry and behavioural science at the University of Chicago, was running an experiment on whether the drug MDMA increased the pleasantness of social touch in healthy volunteers
  • The latest participant in the double-blind trial, a man named Brendan, had filled out a standard questionnaire at the end. Strangely, at the very bottom of the form, Brendan had written in bold letters: "This experience has helped me sort out a debilitating personal issue. Google my name. I now know what I need to do."
  • They googled Brendan's name, and up popped a disturbing revelation: until just a couple of months before, Brendan had been the leader of the US Midwest faction of Identity Evropa, a notorious white nationalist group rebranded in 2019 as the American Identity Movement. Two months earlier, activists at Chicago Antifascist Action had exposed Brendan's identity, and he had lost his job.
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  • "Go ask him what he means by 'I now know what I need to do,'" she instructed Bremmer. "If it's a matter of him picking up an automatic rifle or something, we have to intervene."
  • As he clarified to Bremmer, love is what he had just realised he had to do. "Love is the most important thing," he told the baffled research assistant. "Nothing matters without
  • When de Wit recounted this story to me nearly two years after the fact, she still could hardly believe it. "Isn't that amazing?" she said. "It's what everyone says about this damn drug, that it makes people feel love. To think that a drug could change somebody's beliefs and thoughts without any expectations – it's mind-boggling."
  • Over the past few years, I've been investigating the scientific research and medical potential of MDMA for a book called "I Feel Love: MDMA and the Quest for Connection in a Fractured World". I learnt how this once-vilified drug is now remerging as a therapeutic agent – a role it previously played in the 1970s and 1980s, prior to its criminalisation
  • He attended the notorious "Unite the Right" rally in Charlottesville and quickly rose up the ranks of his organisation, first becoming the coordinator for Illinois and then the entire Midwest. He travelled to Europe and around the US to meet other white nationalist groups, with the ultimate goal of taking the movement mainstream
  • some researchers have begun to wonder if it could be an effective tool for pushing people who are already somehow primed to reconsider their ideology toward a new way of seeing things
  • While MDMA cannot fix societal-level drivers of prejudice and disconnection, on an individual basis it can make a difference. In certain cases, the drug may even be able to help people see through the fog of discrimination and fear that divides so many of us.
  • in December 2021 I paid Brendan a visit
  • What I didn't expect was how ordinary the 31-year-old who answered the door would appear to be: blue plaid button-up shirt, neatly cropped hair, and a friendly smile.
  • Brendan grew up in an affluent Chicago suburb in an Irish Catholic family. He leaned liberal in high school but got sucked into white nationalism at the University of Illinois Urbana-Champaign, where he joined a fraternity mostly composed of conservative Republican men, began reading antisemitic conspiracy books, and fell down a rabbit hole of racist, sexist content online. Brendan was further emboldened by the populist rhetoric of Donald Trump during his presidential campaign. "His speech talking about Mexicans being rapists, the fixation on the border wall and deporting everyone, the Muslim ban – I didn't really get white nationalism until Trump started running for president," Brendan said.
  • If this comes to pass, MDMA – and other psychedelics-assisted therapy – could transform the field of mental health through widespread clinical use in the US and beyond, for addressing trauma and possibly other conditions as well, including substance use disorders, depression and eating disorders.
  • A group of anti-fascist activists published identifying information about him and more than 100 other people in Identity Evropa. He was immediately fired from his job and ostracised by his siblings and friends outside white nationalism.
  • When Brendan saw a Facebook ad in early 2020 for some sort of drug trial at the University of Chicago, he decided to apply just to have something to do and to earn a little money
  • At the time, Brendan was "still in the denial stage" following his identity becoming public, he said. He was racked with regret – not over his bigoted views, which he still held, but over the missteps that had landed him in this predicament.
  • About 30 minutes after taking the pill, he started to feel peculiar. "Wait a second – why am I doing this? Why am I thinking this way?" he began to wonder. "Why did I ever think it was okay to jeopardise relationships with just about everyone in my life?"
  • Just then, Bremmer came to collect Brendan to start the experiment. Brendan slid into an MRI, and Bremmer started tickling his forearm with a brush and asked him to rate how pleasant it felt. "I noticed it was making me happier – the experience of the touch," Brendan recalled. "I started progressively rating it higher and higher." As he relished in the pleasurable feeling, a single, powerful word popped into his mind: connection.
  • It suddenly seemed so obvious: connections with other people were all that mattered. "This is stuff you can't really put into words, but it was so profound," Brendan said. "I conceived of my relationships with other people not as distinct boundaries with distinct entities, but more as we-are-all-on
  • I realised I'd been fixated on stuff that doesn't really matter, and is just so messed up, and that I'd been totally missing the point. I hadn't been soaking up the joy that life has to offer."
  • Brendan hired a diversity, equity, and inclusion consultant to advise him, enrolled in therapy, began meditating, and started working his way through a list of educational books. S still regularly communicates with Brendan and, for his part, thinks that Brendan is serious in his efforts to change
  • "I think he is trying to better himself and work on himself, and I do think that experience with MDMA had an impact on him. It's been a touchstone for growth, and over time, I think, the reflection on that experience has had a greater impact on him than necessarily the experience itself."
  • Brendan is still struggling, though, to make the connections with others that he craves. When I visited him, he'd just spent Thanksgiving alone
  • He also has not completely abandoned his bigoted ideology, and is not sure that will ever be possible. "There are moments when I have racist or antisemitic thoughts, definitely," he said. "But now I can recognise that those kinds of thought patterns are harming me more than anyone else."
  • it's not without precedent. In the 1980s, for example, an acquaintance of early MDMA-assisted therapy practitioner Requa Greer administered the drug to a pilot who had grown up in a racist home and had inherited those views. The pilot had always accepted his bigoted way of thinking as being a normal, accurate reflection of the way things were. MDMA, however, "gave him a clear vision that unexamined racism was both wrong and mean," Greer says
  • Encouraging stories of seemingly spontaneous change appear to be exceptions to the norm, however, and from a neurological point of view, this makes sense
  • Research shows that oxytocin – one of the key hormones that MDMA triggers neurons to release – drives a "tend and defend" response across the animal kingdom. The same oxytocin that causes a mother bear to nurture her newborn, for example, also fuels her rage when she perceives a threat to her cub. In people, oxytocin likewise strengthens caregiving tendencies toward liked members of a person's in-group and strangers perceived to belong to the same group, but it increases hostility toward individuals from disliked groups
  • In a 2010 study published in Science, for example, men who inhaled oxytocin were three times more likely to donate money to members of their team in an economic game, as well as more likely to harshly punish competing players for not donating enough. (Read more: "The surprising downsides of empathy.")
  • According to research published this week in Nature by Johns Hopkins University neuroscientist Gül Dölen, MDMA and other psychedelics – including psilocybin, LSD, ketamine and ibogaine – work therapeutically by reopening a critical period in the brain. Critical periods are finite windows of impressionability that typically occur in childhood, when our brains are more malleable and primed to learn new things
  • Dölen and her colleagues' findings likewise indicate that, without the proper set and setting, MDMA and other psychedelics probably do not reopen critical periods, which means they will not have a spontaneous, revelatory effect for ridding someone of bigoted beliefs.
  • In the West, plenty of members of right-wing authoritarian political movements, including neo-Nazi groups, also have track records of taking MDMA and other psychedelics
  • This suggests, researchers write, that psychedelics are nonspecific, "politically pluripotent" amplifiers of whatever is going on in somebody's head, with no particular directional leaning "on the axes of conservatism-liberalism or authoritarianism-egalitarianism."
  • That said, a growing body of scientific evidence indicates that the human capacity for compassion, kindness, empathy, gratitude, altruism, fairness, trust, and cooperation are core features of our natures
  • As Emory University primatologist Frans de Waal wrote, "Empathy is the one weapon in the human repertoire that can rid us of the curse of xenophobia."
  • Ginsberg also envisions using the drug in workshops aimed at eliminating racism, or as a means of bringing people together from opposite sides of shared cultural histories to help heal intergenerational trauma. "I think all psychedelics have a role to play, but I think MDMA has a particularly key role because you're both expanded and present, heart-open and really able to listen in a new way," Ginsberg says. "That's something really powerful."
  • "If you give MDMA to hard-core haters on each side of an issue, I don't think it'll do a lot of good,"
  • if you start with open-minded people on both sides, then I think it can work. You can improve communications and build empathy between groups, and help people be more capable of analysing the world from a more balanced perspective rather than from fear-based, anxiety-based distrust."
  • In 2021, Ginsberg and Doblin were coauthors on a study investigating the possibility of using ayahuasca – a plant-based psychedelic – in group contexts to bridge divides between Palestinians and Israelis, with positive findings
  • "I kind of have a fantasy that maybe as we get more reacquainted with psychedelics, there could be group-based experiences that build community resiliency and are intentionally oriented toward breaking down barriers between people, having people see things from other perspectives and detribalising our society,
  • "But that's not going to happen on its own. It would have to be intentional, and – if it happens – it would probably take multiple generations."
  • Based on his experience with extremism, Brendan agreed with expert takes that no drug, on its own, will spontaneously change the minds of white supremacists or end political conflict in the US
  • he does think that, with the right framing and mindset, MDMA could be useful for people who are already at least somewhat open to reconsidering their ideologies, just as it was for him. "It helped me see things in a different way that no amount of therapy or antiracist literature ever would have done," he said. "I really think it was a breakthrough experience."
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A Commencement Address Too Honest to Deliver in Person - The Atlantic - 0 views

  • Use this hiatus to do something you would never have done if this emergency hadn’t hit. When the lockdown lifts, move to another state or country. Take some job that never would have made sense if you were worrying about building a career—bartender, handyman, AmeriCorps volunteer.
  • If you use the next two years as a random hiatus, you may not wind up richer, but you’ll wind up more interesting.
  • The biggest way most colleges fail is this: They don’t plant the intellectual and moral seeds students are going to need later, when they get hit by the vicissitudes of life.
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  • If you didn’t study Jane Austen while you were here, you probably lack the capacity to think clearly about making a marriage decision. If you didn’t read George Eliot, then you missed a master class on how to judge people’s character. If you didn’t read Nietzsche, you are probably unprepared to handle the complexities of atheism—and if you didn’t read Augustine and Kierkegaard, you’re probably unprepared to handle the complexities of faith.
  • The list goes on. If you didn’t read de Tocqueville, you probably don’t understand your own country. If you didn’t study Gibbon, you probably lack the vocabulary to describe the rise and fall of cultures and nations.
  • The wisdom of the ages is your inheritance; it can make your life easier. These resources often fail to get shared because universities are too careerist, or because faculty members are more interested in their academic specialties or politics than in teaching undergraduates, or because of a host of other reasons
  • What are you putting into your mind? Our culture spends a lot less time worrying about this, and when it does, it goes about it all wrong.
  • my worry is that, especially now that you’re out of college, you won’t put enough really excellent stuff into your brain.
  • I worry that it’s possible to grow up now not even aware that those upper registers of human feeling and thought exist.
  • The theory of maximum taste says that each person’s mind is defined by its upper limit—the best that it habitually consumes and is capable of consuming.
  • After college, most of us resolve to keep doing this kind of thing, but we’re busy and our brains are tired at the end of the day. Months and years go by. We get caught up in stuff, settle for consuming Twitter and, frankly, journalism. Our maximum taste shrinks.
  • I’m worried about the future of your maximum taste. People in my and earlier generations, at least those lucky enough to get a college education, got some exposure to the classics, which lit a fire that gets rekindled every time we sit down to read something really excellent.
  • the “theory of maximum taste.” This theory is based on the idea that exposure to genius has the power to expand your consciousness. If you spend a lot of time with genius, your mind will end up bigger and broader than if you spend your time only with run-of-the-mill stuff.
  • the whole culture is eroding the skill the UCLA scholar Maryanne Wolf calls “deep literacy,” the ability to deeply engage in a dialectical way with a text or piece of philosophy, literature, or art.
  • “To the extent that you cannot perceive the world in its fullness, to the same extent you will fall back into mindless, repetitive, self-reinforcing behavior, unable to escape.”
  • I can’t say that to you, because it sounds fussy and elitist and OK Boomer. And if you were in front of me, you’d roll your eyes.
  •  
    Or as the neurologist Richard Cytowic put it to Adam Garfinkle, "To the extent that you cannot perceive the world in its fullness, to the same extent you will fall back into mindless, repetitive, self-reinforcing behavior, unable to escape."*
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How the Shoggoth Meme Has Come to Symbolize the State of A.I. - The New York Times - 0 views

  • the Shoggoth had become a popular reference among workers in artificial intelligence, as a vivid visual metaphor for how a large language model (the type of A.I. system that powers ChatGPT and other chatbots) actually works.
  • it was only partly a joke, he said, because it also hinted at the anxieties many researchers and engineers have about the tools they’re building.
  • Since then, the Shoggoth has gone viral, or as viral as it’s possible to go in the small world of hyper-online A.I. insiders. It’s a popular meme on A.I. Twitter (including a now-deleted tweet by Elon Musk), a recurring metaphor in essays and message board posts about A.I. risk, and a bit of useful shorthand in conversations with A.I. safety experts. One A.I. start-up, NovelAI, said it recently named a cluster of computers “Shoggy” in homage to the meme. Another A.I. company, Scale AI, designed a line of tote bags featuring the Shoggoth.
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  • Most A.I. researchers agree that models trained using R.L.H.F. are better behaved than models without it. But some argue that fine-tuning a language model this way doesn’t actually make the underlying model less weird and inscrutable. In their view, it’s just a flimsy, friendly mask that obscures the mysterious beast underneath.
  • In a nutshell, the joke was that in order to prevent A.I. language models from behaving in scary and dangerous ways, A.I. companies have had to train them to act polite and harmless. One popular way to do this is called “reinforcement learning from human feedback,” or R.L.H.F., a process that involves asking humans to score chatbot responses, and feeding those scores back into the A.I. model.
  • Shoggoths are fictional creatures, introduced by the science fiction author H.P. Lovecraft in his 1936 novella “At the Mountains of Madness.” In Lovecraft’s telling, Shoggoths were massive, blob-like monsters made out of iridescent black goo, covered in tentacles and eyes.
  • @TetraspaceWest said, wasn’t necessarily implying that it was evil or sentient, just that its true nature might be unknowable.
  • And it reinforces the notion that what’s happening in A.I. today feels, to some of its participants, more like an act of summoning than a software development process. They are creating the blobby, alien Shoggoths, making them bigger and more powerful, and hoping that there are enough smiley faces to cover the scary parts.
  • “I was also thinking about how Lovecraft’s most powerful entities are dangerous — not because they don’t like humans, but because they’re indifferent and their priorities are totally alien to us and don’t involve humans, which is what I think will be true about possible future powerful A.I.”
  • when Bing’s chatbot became unhinged and tried to break up my marriage, an A.I. researcher I know congratulated me on “glimpsing the Shoggoth.” A fellow A.I. journalist joked that when it came to fine-tuning Bing, Microsoft had forgotten to put on its smiley-face mask.
  • @TetraspaceWest, the meme’s creator, told me in a Twitter message that the Shoggoth “represents something that thinks in a way that humans don’t understand and that’s totally different from the way that humans think.”
  • In any case, the Shoggoth is a potent metaphor that encapsulates one of the most bizarre facts about the A.I. world, which is that many of the people working on this technology are somewhat mystified by their own creations. They don’t fully understand the inner workings of A.I. language models, how they acquire new capabilities or why they behave unpredictably at times. They aren’t totally sure if A.I. is going to be net-good or net-bad for the world.
  • That some A.I. insiders refer to their creations as Lovecraftian horrors, even as a joke, is unusual by historical standards. (Put it this way: Fifteen years ago, Mark Zuckerberg wasn’t going around comparing Facebook to Cthulhu.)
  • If it’s an A.I. safety researcher talking about the Shoggoth, maybe that person is passionate about preventing A.I. systems from displaying their true, Shoggoth-like nature.
  • A great many people are dismissive of suggestions that any of these systems are “really” thinking, because they’re “just” doing something banal (like making statistical predictions about the next word in a sentence). What they fail to appreciate is that there is every reason to suspect that human cognition is “just” doing those exact same things. It matters not that birds flap their wings but airliners don’t. Both fly. And these machines think. And, just as airliners fly faster and higher and farther than birds while carrying far more weight, these machines are already outthinking the majority of humans at the majority of tasks. Further, that machines aren’t perfect thinkers is about as relevant as the fact that air travel isn’t instantaneous. Now consider: we’re well past the Wright flyer level of thinking machine, past the early biplanes, somewhere about the first commercial airline level. Not quite the DC-10, I think. Can you imagine what the AI equivalent of a 777 will be like? Fasten your seatbelts.
  • @thomas h. You make my point perfectly. You’re observing that the way a plane flies — by using a turbine to generate thrust from combusting kerosene, for example — is nothing like the way that a bird flies, which is by using the energy from eating plant seeds to contract the muscles in its wings to make them flap. You are absolutely correct in that observation, but it’s also almost utterly irrelevant. And it ignores that, to a first approximation, there’s no difference in the physics you would use to describe a hawk riding a thermal and an airliner gliding (essentially) unpowered in its final descent to the runway. Further, you do yourself a grave disservice in being dismissive of the abilities of thinking machines, in exactly the same way that early skeptics have been dismissive of every new technology in all of human history. Writing would make people dumb; automobiles lacked the intelligence of horses; no computer could possibly beat a chess grandmaster because it can’t comprehend strategy; and on and on and on. Humans aren’t nearly as special as we fool ourselves into believing. If you want to have any hope of acting responsibly in the age of intelligent machines, you’ll have to accept that, like it or not, and whether or not it fits with your preconceived notions of what thinking is and how it is or should be done … machines can and do think, many of them better than you in a great many ways. b&
  • @BLA. You are incorrect. Everything has nature. Its nature is manifested in making humans react. Sure, no humans, no nature, but here we are. The writer and various sources are not attributing nature to AI so much as admitting that they don’t know what this nature might be, and there are reasons to be scared of it. More concerning to me is the idea that this field is resorting to geek culture reference points to explain and comprehend itself. It’s not so much the algorithm has no soul, but that the souls of the humans making it possible are stupendously and tragically underdeveloped.
  • When even tech companies are saying AI is moving too fast, and the articles land on page 1 of the NYT (there's an old reference), I think the greedy will not think twice about exploiting this technology, with no ethical considerations, at all.
  • @nome sane? The problem is it isn't data as we understand it. We know what the datasets are -- they were used to train the AI's. But once trained, the AI is thinking for itself, with results that have surprised everybody.
  • The unique feature of a shoggoth is it can become whatever is needed for a particular job. There's no actual shape so it's not a bad metaphor, if an imperfect image. Shoghoths also turned upon and destroyed their creators, so the cautionary metaphor is in there, too. A shame more Asimov wasn't baked into AI. But then the conflict about how to handle AI in relation to people was key to those stories, too.
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