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In general, one of the problems with treating depression “is that we’ve got a lot of medications that pretty much do the same thing,” Dr. Aaronson said. And when patients do not respond to those medications, “we don’t have a lot of novel stuff.”

The activity of the vagus nerve is difficult to measure directly, especially given how complex it is. But because some vagus nerve fibers connect with the heart, experts can indirectly measure cardiac vagal tone — or the way in which your nervous system regulates your heart — by looking at your heart rate variability, which are the fluctuations in the amount of time between your heartbeats, on an EKG.

Holding your breath and submerging your face in cold water can trigger the “diving reflex,” a response that slows the heart beat and constricts blood vessels. Some people who have tried it report that it has a calming effect and can even reduce insomnia. Others wrap an ice pack in cloth and place it on their chest to relieve anxiety.

“For wellness, try to maintain high vagus nerve activity through mindfulness, exercise and paced breathing,” Dr. Tracey said. “These are all very good for you.”

Quantum teleportation — what he called “spooky action at a distance” — can transfer information between locations without actually moving the physical matter that holds it.

This technology could profoundly change the way data travels from place to place. It draws on more than a century of research involving quantum mechanics, a field of physics that governs the subatomic realm and behaves unlike anything we experience in our everyday lives. Quantum teleportation not only moves data between quantum computers, but it also does so in such a way that no one can intercept it.

These entangled systems could be electrons, particles of light or other objects. In the Netherlands, Dr. Hanson and his team used what is called a nitrogen vacancy center — a tiny empty space in a synthetic diamond in which electrons can be trapped.

Traditional computers perform calculations by processing “bits” of information, with each bit holding either a 1 or a 0. By harnessing the strange behavior of quantum mechanics, a quantum bit, or qubit, can store a combination of 1 and 0 — a little like how a spinning coin holds the tantalizing possibility that it will turn up either heads or tails when it finally falls flat on the table.

Researchers believe these devices could one day speed the creation of new medicines, power advances in artificial intelligence and summarily crack the encryption that protects computers vital to national security. Across the globe, governments, academic labs, start-ups and tech giants are spending billions of dollars exploring the technology.

Although it cannot move objects from place to place, it can move information by taking advantage of a quantum property called “entanglement”: A change in the state of one quantum system instantaneously affects the state of another, distant one.

“It does not work that way today. Google knows what you are running on its servers.”

The information also cannot be intercepted. A future quantum internet, powered by quantum teleportation, could provide a new kind of encryption that is theoretically unbreakable.

a self-driving car could have avoided choosing between two bad outcomes by making a decision earlier on — the speaker pointed out that, when entering the alley, the car could have determined that the space was narrow and slowed to a speed that would keep everyone safe.

Auditors have to inspect the algorithm without accessing sensitive user data.

Other considerations come into play as well, such as balancing the removal of misinformation with the protection of free speech.

To meet these challenges, Cen and Shah developed an auditing procedure that does not need more than black-box access to the social media algorithm (which respects trade secrets), does not remove content (which avoids issues of censorship), and does not require access to users (which preserves users’ privacy).

which is known to help reduce the spread of misinformation

In labor markets, for example, workers learn their preferences about what kinds of jobs they want, and employers learn their preferences about the qualifications they seek from workers.

But learning can be disrupted by competition

it is indeed possible to get to a stable outcome (workers aren’t incentivized to leave the matching market), with low regret (workers are happy with their long-term outcomes), fairness (happiness is evenly distributed), and high social welfare.

For instance, when Covid-19 cases surged in the pandemic, many cities had to decide what restrictions to adopt, such as mask mandates, business closures, or stay-home orders. They had to act fast and balance public health with community and business needs, public spending, and a host of other considerations.

But of course, no county exists in a vacuum.

These complex interactions matter,

“Accountability, legitimacy, trust — these principles play crucial roles in society and, ultimately, will determine which systems endure with time.” 

Except, all I do all day is tap icons with red dots like a digital version of whack-a-mole, trying to get rid of all the notifications. Research has shown that this constant stimulation on our devices raises the dopamine in our brains, which basically means they are like drugs. 

It's hard to be productive when you stop to look at your phone every 10-12 minutes.

It's true, technology has allowed us to do some pretty incredible things. I can't argue with the fact that it has allowed us to solve problems that were previously insurmountable, but at a very basic level, all of this smart technology has made us dumb. Mostly, I think it's because of how much we now depend on it for even the most basic things. 

Here's the thing. If you don't use a muscle, after a while you'll lose it.  Sure, it's not technically a muscle, but if you stop using your brain because your watch tells you when it's time to go to a meeting, or stand up, or use the bathroom-- can we at least agree you're not getting any smarter? The more we hand over to machines what makes us unique as humans--our ability to think, process, and make decisions--the less we stretch and grow our capacity to do those things. 

Have you ever sat in a restaurant and looked around? Of course not, the last time you were in a restaurant you were busy looking at your phone. But if you had, you would have seen a bunch of other people who were doing the same thing. A room full of people, all sitting at tables with presumably other people they know and have some level of affection for, staring at an illuminated screen. 

But it has also increased the space in our relationships to the point where we don't talk, we Slack.

igital conversations are very different than real-world conversations. When smart technology helps remove barriers to communication, that's a good thing. But when we substitute technology for relationships and real conversations, it has real-world consequences.

Forensic science, which drives the plots of movies and television shows, is accorded great respect by the public. And in the proper hands, it can provide persuasive insight. But in the wrong hands, it can trap innocent people in a vise of seeming inerrancy—and it has done so far too often. What’s more, although some forensic disciplines, such as DNA analysis, are reliable, others have been shown to have serious limitations.

Yezzo is not like Annie Dookhan, a chemist in a Massachusetts crime laboratory who boosted her productivity by falsifying reports and by “dry labbing”—that is, reporting results without actually conducting any tests.

Nor is Yezzo like Michael West, a forensic odontologist who claimed that he could identify bite marks on a victim and then match those marks to a specific person.

The deeper issue with forensic science lies not in malfeasance or corruption—or utter incompetence—but in the gray area where Yezzo can be found. Her alleged personal problems are unusual: Only because of them did the details of her long career come to light.

to the point of alignment; how rarely an analyst’s skills are called into question in court; and how seldom the performance of crime labs is subjected to any true oversight.

More than half of those exonerated by post-conviction DNA testing had been wrongly convicted based on flawed forensic evidence.

The quality of the work done in crime labs is almost never audited.

Even the best forensic scientists can fall prey to unintentional bias.

Study after study has demonstrated the power of cognitive bias.

Cognitive bias can of course affect anyone, in any circumstance—but it is particularly dangerous in a criminal-justice system where forensic scientists have wide latitude as well as some incentive to support the views of prosecutors and the police.

“I have long been interested in classifications of people, in how they affect the people classified, and how the effects on the people in turn change the classifications,” he wrote in “Making Up People

His work in the philosophy of science was groundbreaking: He departed from the preoccupation with questions that had long concerned philosophers. Arguing that science was just as much about intervention as it was about representation, be helped bring experimentation to center stage.

Regarding one such question — whether unseen phenomena like quarks and electrons were real or merely the theoretical constructs of physicists — he argued for reality in the case of phenomena that figured in experiments, citing as an example an experiment at Stanford that involved spraying electrons and positrons into a ball of niobium to detect electric charges. “So far as I am concerned,” he wrote, “if you can spray them, they’re real.”

His book “The Emergence of Probability” (1975), which is said to have inspired hundreds of books by other scholars, examined how concepts of statistical probability have evolved over time, shaping the way we understand not just arcane fields like quantum physics but also everyday life.

“I was trying to understand what happened a few hundred years ago that made it possible for our world to be dominated by probabilities,” he said in a 2012 interview with the journal Public Culture. “We now live in a universe of chance, and everything we do — health, sports, sex, molecules, the climate — takes place within a discourse of probabilities.”

Whatever the subject, whatever the audience, one idea that pervades all his work is that “science is a human enterprise,” Ragnar Fjelland and Roger Strand of the University of Bergen in Norway wrote when Professor Hacking won the Holberg Prize. “It is always created in a historical situation, and to understand why present science is as it is, it is not sufficient to know that it is ‘true,’ or confirmed. We have to know the historical context of its emergence.”

Hacking often argued that as the human sciences have evolved, they have created categories of people, and that people have subsequently defined themselves as falling into those categories. Thus does human reality become socially constructed.

In 2000, he became the first Anglophone to win a permanent position at the Collège de France, where he held the chair in the philosophy and history of scientific concepts until he retired in 2006.

“I call this the ‘looping effect,’” he added. “Sometimes, our sciences create kinds of people that in a certain sense did not exist before.”

In “Why Race Still Matters,” a 2005 article in the journal Daedalus, he explored how anthropologists developed racial categories by extrapolating from superficial physical characteristics, with lasting effects — including racial oppression. “Classification and judgment are seldom separable,” he wrote. “Racial classification is evaluation.”

Similarly, he once wrote, in the field of mental health the word “normal” “uses a power as old as Aristotle to bridge the fact/value distinction, whispering in your ear that what is normal is also right.”

In his influential writings about autism, Professor Hacking charted the evolution of the diagnosis and its profound effects on those diagnosed, which in turn broadened the definition to include a greater number of people.

Encouraging children with autism to think of themselves that way “can separate the child from ‘normalcy’ in a way that is not appropriate,” he told Public Culture. “By all means encourage the oddities. By no means criticize the oddities.”

His emphasis on historical context also illuminated what he called transient mental illnesses, which appear to be so confined 0cto their time 0c 0cthat they can vanish when times change.

“hysterical fugue” was a short-lived epidemic of compulsive wandering that emerged in Europe in the 1880s, largely among middle-class men who had become transfixed by stories of exotic locales and the lure of trave

His intellectual tendencies were unmistakable from an early age. “When he was 3 or 4 years old, he would sit and read the dictionary,” Jane Hacking said. “His parents were completely baffled.”

He wondered aloud, the interviewer noted, if the whole universe was governed by nonlocality — if “everything in the universe is aware of everything else.”“That’s what you should be writing about,” he said. “Not me. I’m a dilettante. My governing word is ‘curiosity.’”

In 1972, using duct tape and spare parts in the basement on the campus of the University of California, Berkeley, Dr. Clauser and a graduate student, Stuart Freedman, who died in 2012, endeavored to perform Bell’s experiment to measure quantum entanglement. In a series of experiments, he fired thousands of light particles, or photons, in opposite directions to measure a property known as polarization, which could have only two values — up or down. The result for each detector was always a series of seemingly random ups and downs. But when the two detectors’ results were compared, the ups and downs matched in ways that neither “classical physics” nor Einstein’s laws could explain. Something weird was afoot in the universe. Entanglement seemed to be real.

in 2002, Dr. Clauser admitted that he himself had expected quantum mechanics to be wrong and Einstein to be right. “Obviously, we got the ‘wrong’ result. I had no choice but to report what we saw, you know, ‘Here’s the result.’ But it contradicts what I believed in my gut has to be true.” He added, “I hoped we would overthrow quantum mechanics. Everyone else thought, ‘John, you’re totally nuts.’”

the correlations only showed up after the measurements of the individual particles, when the physicists compared their results after the fact. Entanglement seemed real, but it could not be used to communicate information faster than the speed of light.

In 1982, Dr. Aspect and his team at the University of Paris tried to outfox Dr. Clauser’s loophole by switching the direction along which the photons’ polarizations were measured every 10 nanoseconds, while the photons were already in the air and too fast for them to communicate with each other. He too, was expecting Einstein to be right.

Quantum predictions held true, but there were still more possible loopholes in the Bell experiment that Dr. Clauser had identified

For example, the polarization directions in Dr. Aspect’s experiment had been changed in a regular and thus theoretically predictable fashion that could be sensed by the photons or detectors.

Anton Zeilinger

added even more randomness to the Bell experiment, using random number generators to change the direction of the polarization measurements while the entangled particles were in flight.

Once again, quantum mechanics beat Einstein by an overwhelming margin, closing the “locality” loophole.

as scientists have done more experiments with entangled particles, entanglement is accepted as one of main features of quantum mechanics and is being put to work in cryptology, quantum computing and an upcoming “quantum internet

One of its first successes in cryptology is messages sent using entangled pairs, which can send cryptographic keys in a secure manner — any eavesdropping will destroy the entanglement, alerting the receiver that something is wrong.

, with quantum mechanics, just because we can use it, doesn’t mean our ape brains understand it. The pioneering quantum physicist Niels Bohr once said that anyone who didn’t think quantum mechanics was outrageous hadn’t understood what was being said.

In his interview with A.I.P., Dr. Clauser said, “I confess even to this day that I still don’t understand quantum mechanics, and I’m not even sure I really know how to use it all that well. And a lot of this has to do with the fact that I still don’t understand it.”

“I continued to be duped by ChatGPT. It’s embarrassing,” Mr. Schwartz said.

As Mr. Schwartz answered the judge’s questions, the reaction in the courtroom, crammed with close to 70 people who included lawyers, law students, law clerks and professors, rippled across the benches. There were gasps, giggles and sighs. Spectators grimaced, darted their eyes around, chewed on pens.

“This case has reverberated throughout the entire legal profession,” said David Lat, a legal commentator. “It is a little bit like looking at a car wreck.”

The episode, which arose in an otherwise obscure lawsuit, has riveted the tech world, where there has been a growing debate about the dangers — even an existential threat to humanity — posed by artificial intelligence. It has also transfixed lawyers and judges.

Avianca asked Judge Castel to dismiss the lawsuit because the statute of limitations had expired. Mr. Mata’s lawyers responded with a 10-page brief citing more than half a dozen court decisions, with names like Martinez v. Delta Air Lines, Zicherman v. Korean Air Lines and Varghese v. China Southern Airlines, in support of their argument that the suit should be allowed to proceed.After Avianca’s lawyers could not locate the cases, Judge Castel ordered Mr. Mata’s lawyers to provide copies. They submitted a compendium of decisions.It turned out the cases were not real.

Mr. Schwartz, who has practiced law in New York for 30 years, said in a declaration filed with the judge this week that he had learned about ChatGPT from his college-aged children and from articles, but that he had never used it professionally.He told Judge Castel on Thursday that he had believed ChatGPT had greater reach than standard databases.“I heard about this new site, which I falsely assumed was, like, a super search engine,” Mr. Schwartz said.

Irina Raicu, who directs the internet ethics program at Santa Clara University, said this week that the Avianca case clearly showed what critics of such models have been saying, “which is that the vast majority of people who are playing with them and using them don’t really understand what they are and how they work, and in particular what their limitations are.”

“This case has changed the urgency of it,” Professor Roiphe said. “There’s a sense that this is not something that we can mull over in an academic way. It’s something that has affected us right now and has to be addressed.”

In the declaration Mr. Schwartz filed this week, he described how he had posed questions to ChatGPT, and each time it seemed to help with genuine case citations. He attached a printout of his colloquy with the bot, which shows it tossing out words like “sure” and “certainly!”After one response, ChatGPT said cheerily, “I hope that helps!”

Why some people can shake off the impulse to eat, and other people stay mired in thoughts about food, is “the million-dollar question,”

There’s another theoretical framework for why Ozempic might quash food noise: Semaglutide activates receptors for a hormone called GLP-1. Studies in animals have shown those receptors are found in cells in regions of the brain that are particularly important for motivation and reward, pointing to one potential way semaglutide could influence cravings and desires.

Ms. Klemmer said she worried about the potential long-term side effects of a medication she might be on for the rest of her life. But she thinks the trade-off — the end of food noise — is worth it. “It’s worth every bad side effect that I’d have to go through to have what I feel now,” she said: “not caring about food.”

we’re networked organisms who move around in shifting surroundings, environments that have the power to transform our thinking

Annie Murphy Paul’s new book, “The Extended Mind,” which exhorts us to use our entire bodies, our surroundings and our relationships to “think outside the brain.”

In 2011, she published “Origins,” which focused on all the ways we are shaped by the environment, before birth and minute to minute thereafter.

“In the nature-nurture dynamic, nurture begins at the time of conception. The food the mother eats, the air she breathes, the water she drinks, the stress or trauma she experiences — all may affect her child for better or worse, over the decades to come.”

a down-to-earth take on the science of epigenetics — how environmental signals become catalysts for gene expression

the parallel to this latest book is that the boundaries we commonly assume to be fixed are actually squishy. The moment of a child’s birth, her I.Q. scores or fMRI snapshots of what’s going on inside her brain — all are encroached upon and influenced by outside forces.

awareness of our internal signals, such as exactly when our hearts beat, or how cold and clammy our hands are, can boost our performance at the poker table or in the financial markets, and even improve our pillow talk

“Though we typically think of the brain as telling the body what to do, just as much does the body guide the brain with an array of subtle nudges and prods. One psychologist has called this guide our ‘somatic rudder,’

The “body scan” aspect of mindfulness meditation that has been deployed by the behavioral medicine pioneer Jon Kabat-Zinn may help people lower their heart rates and blood pressure,

techniques that help us pinpoint their signals can foster well-being

Tania Singer has shown how the neural circuitry underlying compassion is strengthened by meditation practice

our thoughts “are powerfully shaped by the way we move our bodies.” Gestures help us understand spatial concepts; indeed, “without gesture as an aid, students may fail to understand spatial ideas at all,”

looking out on grassy expanses near loose clumps of trees and a source of water helps us solve problems. “Passive attention,” she writes, is “effortless: diffuse and unfocused, it floats from object to object, topic to topic. This is the kind of attention evoked by nature, with its murmuring sounds and fluid motions; psychologists working in the tradition of James call this state of mind ‘soft fascination.’”

The chapters on the ways natural and built spaces reflect universal preferences and enhance the thinking process felt like a respite

But one piece of advice almost no one is giving? Be lucky. Pediatrician Neil Stone says that there’s no “secret” for staying Covid-19 free because there’s just too much luck involved.

As for me, I have some data that can, to an extent, quantify and explain my own good luck in avoiding Covid so far. I’m participating in a study on immunity which allowed me to learn that my blood still carries loads of antibodies induced by my vaccine and December booster shot, and no signs of any prior infection. Not everyone’s antibodies wane at the same rate, and in some people, the antibodies don’t wane much at all. (At some point it should become routine to collect this information to help people decide whether to get additional booster shots.)

My high level of vaccine antibodies probably explains my success more than my behavior. I make some effort to avoid Covid, but have been far from perfect. And I’ve been potentially exposed at least twice: Once last December, when someone at a small holiday gathering I’d attended developed symptoms the next day, and more recently, when I shared a large indoor space with two people who later tested positive. But according to my lab work, I’ve never had even a silent infection.

It’s possible I was protected by my high antibodies, or that some quirk of air flow meant I never breathed in enough virus to get sick. Or perhaps I benefited from a different form of luck. There’s another facet to immunity called the innate immune system, which acts as a first line of defense and sometimes knocks out a virus or other pathogen before it replicates enough to elicit the production of antibodies. Good innate immunity might help explain something many of us have experienced — not getting a cold or flu even when sleeping in the same bed with the sick person through the whole illness.

Stress, diet, general health and even sunlight might all affect innate immunity. So could other factors. There’s so much we still don’t know about the immune system. And that’s one reason we talk about “luck.”

understanding how the luck works could help other people avoid Covid, whether for the first time or for the second or third time. Taking a closer look at what passed for luck helped researchers like Gary Taubes discover that public health had obesity all wrong, and the standard high carb/low fat diets were causing people to gain weight.

a failure to seriously consider the implications of an invention as it becomes entrenched in society; a deep trust in networks, in the idea that allowing people to more freely associate would redound mainly to the good of society; and too much affection for the culture of Silicon Valley and the idea that the people who created a certain thing must have some clue about what to do with it.

I got carried away by the excitement of new tech.

Social networks, I observed, got better as more people used them; it seemed reasonable that at some point one social network would gain widespread acceptance and become a comprehensive directory for connecting everyone.

As an immigrant, I’d also bought into the world-shrinking implications of such a network.

I didn’t consider the far-reaching implications of Facebook’s ubiquity.

What I’d failed to consider was how all these various new things would interact with one another, especially as more people got online.

in calling for everyone to get on Facebook, I should have made a better stab at guessing what could go wrong if we all did. What would be the implications for privacy if we were all using Facebook on our phones — how much could this one service glean about you by being in your pocket all the time?

What would the implications for speech and media be if this single company became a central clearinghouse in the global discourse?

I trusted techies.

This was the vibe pervading media and politics in the late 2000s: Wall Street had ruined the world. Silicon Valley could put it right.

It does not seem in any way good for society — for the economy, for politics, for a basic sense of equality — that a handful of hundred-billion-dollar or even trillion-dollar companies should control such large swathes of the internet.

Obama’s regulators allowed Facebook to buy up its biggest competitors — first Instagram, then WhatsApp — and failed to crack down on its recklessness with users’ private data

Life brings an accumulation of unremitting stress, especially for those subjected to inequity — and not just from immediate and chronic threats. Even the anticipation of those menaces causes persistent damage.

The body produces too much cortisol and other stress hormones, straining to bring itself back to normal. Eventually, the body’s machinery malfunctions.

The constant strain — the chronic sources of stress — resets what is “normal,” and the body begins to change.

t is the repeated triggering of this process year after year — the persistence of striving to overcome barriers — that leads to poor health.

Blood pressure remains high. Inflammation turns chronic. In the arteries, plaque forms, causing the linings of blood vessels to thicken and stiffen. That forces the heart to work harder. It doesn’t stop there. Other organs begin to fail.

, that people’s varied life experiences affect their health by wearing down their bodies. And second, she said: “People are not just passive victims of these horrible exposures. They withstand them. They struggle against them. These are people who weather storms.”

It isn’t just living in an unequal society that makes people sick. It’s the day-in, day-out effort of trying to be equal that wears bodies down.

Weathering doesn’t start in middle age.

It begins in the womb. Cortisol released into a pregnant person’s bloodstream crosses the placenta, which helps explain why a disproportionate number of babies born to parents who live in impoverished communities or who experience the constant scorn of discrimination are preterm and too small.

The argument weathering is trying to make is these are things we can change, but we have to understand them in their complexity,” Geronimus said. “This has to be a societal project, not the new app on your phone that will remind you to take deep breaths when you’re feeling stress.”

Following what it described as Meta’s unsatisfactory response to its complaints, Match began canceling Meta advertising for some of its apps, such as Tinder, in October. It has since halted all Reels advertising and stopped promoting its major brands on any of Meta’s platforms. “We have no desire to pay Meta to market our brands to predators or place our ads anywhere near this content,” said Match spokeswoman Justine Sacco.

The Journal set up the test accounts after observing that the thousands of followers of such young people’s accounts often include large numbers of adult men, and that many of the accounts who followed those children also had demonstrated interest in sex content related to both children and adults

The Journal also tested what the algorithm would recommend after its accounts followed some of those users as well, which produced more-disturbing content interspersed with ads.

The Canadian Centre for Child Protection, a child-protection group, separately ran similar tests on its own, with similar results.

Meta said the Journal’s tests produced a manufactured experience that doesn’t represent what billions of users see. The company declined to comment on why the algorithms compiled streams of separate videos showing children, sex and advertisements, but a spokesman said that in October it introduced new brand safety tools that give advertisers greater control over where their ads appear, and that Instagram either removes or reduces the prominence of four million videos suspected of violating its standards each month. 

The Journal reported in June that algorithms run by Meta, which owns both Facebook and Instagram, connect large communities of users interested in pedophilic content. The Meta spokesman said a task force set up after the Journal’s article has expanded its automated systems for detecting users who behave suspiciously, taking down tens of thousands of such accounts each month. The company also is participating in a new industry coalition to share signs of potential child exploitation.

“Our systems are effective at reducing harmful content, and we’ve invested billions in safety, security and brand suitability solutions,” said Samantha Stetson, a Meta vice president who handles relations with the advertising industry. She said the prevalence of inappropriate content on Instagram is low, and that the company invests heavily in reducing it.

Even before the 2020 launch of Reels, Meta employees understood that the product posed safety concerns, according to former employees.

Robbie McKay, a spokesman for Bumble, said it “would never intentionally advertise adjacent to inappropriate content,” and that the company is suspending its ads across Meta’s platforms.

Meta created Reels to compete with TikTok, the video-sharing platform owned by Beijing-based ByteDance. Both products feed users a nonstop succession of videos posted by others, and make money by inserting ads among them. Both companies’ algorithms show to a user videos the platforms calculate are most likely to keep that user engaged, based on his or her past viewing behavior

The Journal reporters set up the Instagram test accounts as adults on newly purchased devices and followed the gymnasts, cheerleaders and other young influencers. The tests showed that following only the young girls triggered Instagram to begin serving videos from accounts promoting adult sex content alongside ads for major consumer brands, such as one for Walmart that ran after a video of a woman exposing her crotch. 

When the test accounts then followed some users who followed those same young people’s accounts, they yielded even more disturbing recommendations. The platform served a mix of adult pornography and child-sexualizing material, such as a video of a clothed girl caressing her torso and another of a child pantomiming a sex act.

Experts on algorithmic recommendation systems said the Journal’s tests showed that while gymnastics might appear to be an innocuous topic, Meta’s behavioral tracking has discerned that some Instagram users following preteen girls will want to engage with videos sexualizing children, and then directs such content toward them.

Instagram’s system served jarring doses of salacious content to those test accounts, including risqué footage of children as well as overtly sexual adult videos—and ads for some of the biggest U.S. brands.

Preventing the system from pushing noxious content to users interested in it, they said, requires significant changes to the recommendation algorithms that also drive engagement for normal users. Company documents reviewed by the Journal show that the company’s safety staffers are broadly barred from making changes to the platform that might reduce daily active users by any measurable amount.

The test accounts showed that advertisements were regularly added to the problematic Reels streams. Ads encouraging users to visit Disneyland for the holidays ran next to a video of an adult acting out having sex with her father, and another of a young woman in lingerie with fake blood dripping from her mouth. An ad for Hims ran shortly after a video depicting an apparently anguished woman in a sexual situation along with a link to what was described as “the full video.”

Current and former Meta employees said in interviews that the tendency of Instagram algorithms to aggregate child sexualization content from across its platform was known internally to be a problem. Once Instagram pigeonholes a user as interested in any particular subject matter, they said, its recommendation systems are trained to push more related content to them.

Part of the problem is that automated enforcement systems have a harder time parsing video content than text or still images. Another difficulty arises from how Reels works: Rather than showing content shared by users’ friends, the way other parts of Instagram and Facebook often do, Reels promotes videos from sources they don’t follow

In an analysis conducted shortly before the introduction of Reels, Meta’s safety staff flagged the risk that the product would chain together videos of children and inappropriate content, according to two former staffers. Vaishnavi J, Meta’s former head of youth policy, described the safety review’s recommendation as: “Either we ramp up our content detection capabilities, or we don’t recommend any minor content,” meaning any videos of children.

At the time, TikTok was growing rapidly, drawing the attention of Instagram’s young users and the advertisers targeting them. Meta didn’t adopt either of the safety analysis’s recommendations at that time, according to J.

Stetson, Meta’s liaison with digital-ad buyers, disputed that Meta had neglected child safety concerns ahead of the product’s launch. “We tested Reels for nearly a year before releasing it widely, with a robust set of safety controls and measures,” she said. 

After initially struggling to maximize the revenue potential of its Reels product, Meta has improved how its algorithms recommend content and personalize video streams for users

Among the ads that appeared regularly in the Journal’s test accounts were those for “dating” apps and livestreaming platforms featuring adult nudity, massage parlors offering “happy endings” and artificial-intelligence chatbots built for cybersex. Meta’s rules are supposed to prohibit such ads.

The Journal informed Meta in August about the results of its testing. In the months since then, tests by both the Journal and the Canadian Centre for Child Protection show that the platform continued to serve up a series of videos featuring young children, adult content and apparent promotions for child sex material hosted elsewhere. 

As of mid-November, the center said Instagram is continuing to steadily recommend what the nonprofit described as “adults and children doing sexual posing.”

Meta hasn’t offered a timetable for resolving the problem or explained how in the future it would restrict the promotion of inappropriate content featuring children. 

The Journal’s test accounts found that the problem even affected Meta-related brands. Ads for the company’s WhatsApp encrypted chat service and Meta’s Ray-Ban Stories glasses appeared next to adult pornography. An ad for Lean In Girls, the young women’s empowerment nonprofit run by former Meta Chief Operating Officer Sheryl Sandberg, ran directly before a promotion for an adult sex-content creator who often appears in schoolgirl attire. Sandberg declined to comment. 

Through its own tests, the Canadian Centre for Child Protection concluded that Instagram was regularly serving videos and pictures of clothed children who also appear in the National Center for Missing and Exploited Children’s digital database of images and videos confirmed to be child abuse sexual material. The group said child abusers often use the images of the girls to advertise illegal content for sale in dark-web forums.

The nature of the content—sexualizing children without generally showing nudity—reflects the way that social media has changed online child sexual abuse, said Lianna McDonald, executive director for the Canadian center. The group has raised concerns about the ability of Meta’s algorithms to essentially recruit new members of online communities devoted to child sexual abuse, where links to illicit content in more private forums proliferate.

“Time and time again, we’ve seen recommendation algorithms drive users to discover and then spiral inside of these online child exploitation communities,” McDonald said, calling it disturbing that ads from major companies were subsidizing that process.

The Lancet and the University College London Institute for Global Health Commission called climate change the biggest threat to global health—and mental health in particular—of the 21st century (The Lancet, Vol. 373, No. 9676, 2009).

Humans have evolved to adjust to some environmental stressors, researchers have found, through allostasis, the system by which the body responds to stress.

The greater the stressors and the longer we are exposed to them, the more likely our response systems are to fail—and those stress responses may remain elevated for the rest of our lives (Crews, D. E., et al., Annals of Human Biology , Vol. 46, No. 1, 2019)

In 2017, for example, APA and ecoAmerica defined “eco-anxiety” as “a chronic fear of environmental doom” (APA and ecoAmerica, 2017).

It’s not just those directly affected by a disaster who suffer. Often, simply knowing that others are in the path of disaster can trigger anxiety or depression, says Amy Lykins, PhD, an American clinical psychologist and researcher working in Australia and in South Pacific islands such as Fiji

It is normal for people to be worried about environmental issues—it isn’t a disorder to be stressed by stressors. “We certainly don’t want to pathologize someone’s reasonable distress about climate and environmental threats,” Doherty says. “But we also don’t want to minimize issues that are causing significant impairment to a person’s life.”

According to the February 2020 APA poll, 4 in 10 people have not changed their behavior in light of climate change, but 7 in 10 say they wish they could do more, while 5 in 10 say they don’t know where to begin

Other research bears this out: Even when people are concerned about climate change and the environment, they may feel paralyzed or useless when it comes to taking action (Landry, N., et al., Journal of Environmental Psychology , Vol. 55, 2018).

Even as a liberal who has attended abortion rights demonstrations and written about standing up to racism, I sometimes feel afraid to fully speak my mind.

In the classroom, backlash for unpopular opinions is so commonplace that many students have stopped voicing them, sometimes fearing lower grades if they don’t censor themselves.

According to a 2021 survey administered by College Pulse of over 37,000 students at 159 colleges, 80 percent of students self-censor at least some of the time.

Forty-eight percent of undergraduate students described themselves as “somewhat uncomfortable” or “very uncomfortable” with expressing their views on a controversial topic in the classroom.

When a class discussion goes poorly for me, I can tell.

The room felt tense. I saw people shift in their seats. Someone got angry, and then everyone seemed to get angry. After the professor tried to move the discussion along, I still felt uneasy. I became a little less likely to speak up again and a little less trusting of my own thoughts.

This anxiety affects not just conservatives. I spoke with Abby Sacks, a progressive fourth-year student. She said she experienced a “pile-on” during a class discussion about sexism in media

Throughout that semester, I saw similar reactions in response to other students’ ideas. I heard fewer classmates speak up. Eventually, our discussions became monotonous echo chambers. Absent rich debate and rigor, we became mired in socially safe ideas.

when criticism transforms into a public shaming, it stifles learning.

Professors have noticed a shift in their classrooms

I went to college to learn from my professors and peers. I welcomed an environment that champions intellectual diversity and rigorous disagreement

“Second, the dominant messages students hear from faculty, administrators and staff are progressive ones. So they feel an implicit pressure to conform to those messages in classroom and campus conversations and debates.”

I met Stephen Wiecek at our debate club. He’s an outgoing, formidable first-year debater who often stays after meetings to help clean up. He’s also conservative.

He told me that he has often “straight-up lied” about his beliefs to avoid conflict. Sometimes it’s at a party, sometimes it’s at an a cappella rehearsal, and sometimes it’s in the classroom. When politics comes up, “I just kind of go into survival mode,” he said. “I tense up a lot more, because I’ve got to think very carefully about how I word things. It’s very anxiety inducing.”

“First, students are afraid of being called out on social media by their peers,”

“It was just a succession of people, one after each other, each vehemently disagreeing with me,” she told me.

Ms. Sacks felt overwhelmed. “Everyone adding on to each other kind of energized the room, like everyone wanted to be part of the group with the correct opinion,” she said. The experience, she said, “made me not want to go to class again.” While Ms. Sacks did continue to attend the class, she participated less frequently. She told me that she felt as if she had become invisible.

Other campuses also struggle with this. “Viewpoint diversity is no longer considered a sacred, core value in higher education,”

Dr. Abrams said the environment on today’s campuses differs from his undergraduate experience. He recalled late-night debates with fellow students that sometimes left him feeling “hurt” but led to “the ecstasy of having my mind opened up to new ideas.”

He worries that self-censorship threatens this environment and argues that college administrations in particular “enforce and create a culture of obedience and fear that has chilled speech.”

Universities must do more than make public statements supporting free expression. We need a campus culture that prioritizes ideological diversity and strong policies that protect expression in the classroom.

Universities should refuse to cancel controversial speakers or cave to unreasonable student demands. They should encourage professors to reward intellectual diversity and nonconformism in classroom discussions. And most urgently, they should discard restrictive speech codes and bias response teams that pathologize ideological conflict.

We cannot experience the full benefits of a university education without having our ideas challenged, yet challenged in ways that allow us to grow.

Using tech devices is addictive, and it's becoming more and more difficult to disengage with their technology.In fact, the average US adult spends more than 11 hours daily in the digital world

These days, we have a world of information at our fingertips via the internet. While this is useful, it does have some drawbacks. Entrepreneur Beth Haggerty said she finds that it "limits pure creative thought, at times, because we are developing habits to Google everything to quickly find an answer."

young adults who use seven to 11 social media platforms had more than three times the risk of depression and anxiety than those who use two or fewer platforms.

Another social skill that technology is helping to erode is young people's ability to read body language and nuance in face-to-face encounters.

Technology can have a negative impact on relationships, particularly when it affects how we communicate.One of the primary issues is that misunderstandings are much more likely to occur when communicating via text or email

Can you imagine doing your job without the help of technology of any kind? What about communicating? Or traveling? Or entertaining yourself?

Smartphone slouch. Desk slump. Text neck. Whatever you call it, the way we hold ourselves when we use devices like phones, computers, and tablets isn't healthy.

Studies have found that simply talking on the phone while walking actually slows down and disrupts our gait

When our brain is processing complex emotions and stressors, it hinders our ability to function at our best.

As I tell my students, remember to play your whole movie — not just the clip of your latest stumble on repeat

If a phone call is enough to disrupt our performance of basic tasks, we should be especially mindful of cognitive loads associated with grief, loss and general uncertainty about what is to come. All are major triggers for depression and anxiety, and profoundly affect our ability to perform even the most routine, practiced tasks.

holding tightly on to our latest failures is a common phenomenon, thanks to the recency effect — a cognitive bias that prioritizes our most recent experiences over past ones. This natural tendency sends our brain the wrong messages, and makes us forget how skilled, credentialed or qualified we really are

Adult depression and anxiety has climbed by 5.1 percent since the start of the pandemic.

Those things won’t matter nearly as much as their willingness to try again.

The girls who came to us had many comorbidities: depression, anxiety, ADHD, eating disorders, obesity. Many were diagnosed with autism, or had autism-like symptoms. A report last year on a British pediatric transgender center found that about one-third of the patients referred there were on the autism spectrum.

This concerned me, but didn’t feel I was in the position to sound some kind of alarm back then. There was a team of about eight of us, and only one other person brought up the kinds of questions I had. Anyone who raised doubts ran the risk of being called a transphobe. 

I certainly saw this at the center. One of my jobs was to do intake for new patients and their families. When I started there were probably 10 such calls a month. When I left there were 50, and about 70 percent of the new patients were girls. Sometimes clusters of girls arrived from the same high school. 

There are no reliable studies showing this. Indeed, the experiences of many of the center’s patients prove how false these assertions are. 

The doctors privately recognized these false self-diagnoses as a manifestation of social contagion. They even acknowledged that suicide has an element of social contagion. But when I said the clusters of girls streaming into our service looked as if their gender issues might be a manifestation of social contagion, the doctors said gender identity reflected something innate.

To begin transitioning, the girls needed a letter of support from a therapist—usually one we recommended—who they had to see only once or twice for the green light. To make it more efficient for the therapists, we offered them a template for how to write a letter in support of transition. The next stop was a single visit to the endocrinologist for a testosterone prescription. 

When a female takes testosterone, the profound and permanent effects of the hormone can be seen in a matter of months. Voices drop, beards sprout, body fat is redistributed. Sexual interest explodes, aggression increases, and mood can be unpredictable. Our patients were told about some side effects, including sterility. But after working at the center, I came to believe that teenagers are simply not capable of fully grasping what it means to make the decision to become infertile while still a minor.

Many encounters with patients emphasized to me how little these young people understood the profound impacts changing gender would have on their bodies and minds. But the center downplayed the negative consequences, and emphasized the need for transition. As the center’s website said, “Left untreated, gender dysphoria has any number of consequences, from self-harm to suicide. But when you take away the gender dysphoria by allowing a child to be who he or she is, we’re noticing that goes away. The studies we have show these kids often wind up functioning psychosocially as well as or better than their peers.” 

Frequently, our patients declared they had disorders that no one believed they had. We had patients who said they had Tourette syndrome (but they didn’t); that they had tic disorders (but they didn’t); that they had multiple personalities (but they didn’t).

Here’s an example. On Friday, May 1, 2020, a colleague emailed me about a 15-year-old male patient: “Oh dear. I am concerned that [the patient] does not understand what Bicalutamide does.” I responded: “I don’t think that we start anything honestly right now.”

Bicalutamide is a medication used to treat metastatic prostate cancer, and one of its side effects is that it feminizes the bodies of men who take it, including the appearance of breasts. The center prescribed this cancer drug as a puberty blocker and feminizing agent for boys. As with most cancer drugs, bicalutamide has a long list of side effects, and this patient experienced one of them: liver toxicity. He was sent to another unit of the hospital for evaluation and immediately taken off the drug. Afterward, his mother sent an electronic message to the Transgender Center saying that we were lucky her family was not the type to sue.

How little patients understood what they were getting into was illustrated by a call we received at the center in 2020 from a 17-year-old biological female patient who was on testosterone. She said she was bleeding from the vagina. In less than an hour she had soaked through an extra heavy pad, her jeans, and a towel she had wrapped around her waist. The nurse at the center told her to go to the emergency room right away.

when there was a dispute between the parents, it seemed the center always took the side of the affirming parent.

Other girls were disturbed by the effects of testosterone on their clitoris, which enlarges and grows into what looks like a microphallus, or a tiny penis. I counseled one patient whose enlarged clitoris now extended below her vulva, and it chafed and rubbed painfully in her jeans. I advised her to get the kind of compression undergarments worn by biological men who dress to pass as female. At the end of the call I thought to myself, “Wow, we hurt this kid.”

There are rare conditions in which babies are born with atypical genitalia—cases that call for sophisticated care and compassion. But clinics like the one where I worked are creating a whole cohort of kids with atypical genitals—and most of these teens haven’t even had sex yet. They had no idea who they were going to be as adults. Yet all it took for them to permanently transform themselves was one or two short conversations with a therapist.

Being put on powerful doses of testosterone or estrogen—enough to try to trick your body into mimicking the opposite sex—-affects the rest of the body. I doubt that any parent who's ever consented to give their kid testosterone (a lifelong treatment) knows that they’re also possibly signing their kid up for blood pressure medication, cholesterol medication, and perhaps sleep apnea and diabetes. 

Besides teenage girls, another new group was referred to us: young people from the inpatient psychiatric unit, or the emergency department, of St. Louis Children’s Hospital. The mental health of these kids was deeply concerning—there were diagnoses like schizophrenia, PTSD, bipolar disorder, and more. Often they were already on a fistful of pharmaceuticals.

no matter how much suffering or pain a child had endured, or how little treatment and love they had received, our doctors viewed gender transition—even with all the expense and hardship it entailed—as the solution.

Another disturbing aspect of the center was its lack of regard for the rights of parents—and the extent to which doctors saw themselves as more informed decision-makers over the fate of these children.

We found out later this girl had had intercourse, and because testosterone thins the vaginal tissues, her vaginal canal had ripped open. She had to be sedated and given surgery to repair the damage. She wasn’t the only vaginal laceration case we heard about.

During the four years I worked at the clinic as a case manager—I was responsible for patient intake and oversight—around a thousand distressed young people came through our doors. The majority of them received hormone prescriptions that can have life-altering consequences—including sterility. 

I left the clinic in November of last year because I could no longer participate in what was happening there. By the time I departed, I was certain that the way the American medical system is treating these patients is the opposite of the promise we make to “do no harm.” Instead, we are permanently harming the vulnerable patients in our care.

Today I am speaking out. I am doing so knowing how toxic the public conversation is around this highly contentious issue—and the ways that my testimony might be misused. I am doing so knowing that I am putting myself at serious personal and professional risk.

Almost everyone in my life advised me to keep my head down. But I cannot in good conscience do so. Because what is happening to scores of children is far more important than my comfort. And what is happening to them is morally and medically appalling.

For almost four years, I worked at The Washington University School of Medicine Division of Infectious Diseases with teens and young adults who were HIV positive. Many of them were trans or otherwise gender nonconforming, and I could relate: Through childhood and adolescence, I did a lot of gender questioning myself. I’m now married to a transman, and together we are raising my two biological children from a previous marriage and three foster children we hope to adopt. 

The center’s working assumption was that the earlier you treat kids with gender dysphoria, the more anguish you can prevent later on. This premise was shared by the center’s doctors and therapists. Given their expertise, I assumed that abundant evidence backed this consensus. 

All that led me to a job in 2018 as a case manager at The Washington University Transgender Center at St. Louis Children's Hospital, which had been established a year earlier.