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johnsonel7

Remember This: Memory Requires Intelligent Design | Evolution News - 0 views

  • Evidence from a new study shows that memory circuits assist the mind in recalling thoughts by associating them with sensations. The mind can use the brain’s storage mechanisms to sort more important or urgent memories for faster recall. 
  • In particular, it remains unknown whether factors that structure the retrieval of external stimuli also apply to thought recall, and whether some thought features affect their accessibility in memory.
  • These observations appear to support the view that the conscious self uses memory as a tool. The mind uses the brain; it is not a passive illusion conjured up by the brain. The brain is active and ready, storing each sensation as we walk through daily life, but thoughts that involve planning are more readily recalled. It’s as if the self tells the brain, “Remember this,” and the brain obliges like a computer operator or librarian, pigeonholing the data where it can be recalled more easily later.
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  • Many of these thoughts are likely forgotten, the authors say, probably because there is only so much a person can focus on in the sea of perceptions and stimuli going on around us. If the intuition is valuable enough to the self, the brain will assist future recall of the intuition
  • They also fit well with the idea that the greater accessibility of planning thoughts in memory results from an evolutionary process whereby mental contents that enhance survival chances are better remembered.
anniina03

Marine Labs on the Water's Edge Are Threatened by Climate Change - The New York Times - 0 views

  • A marine laboratory 85 miles southwest of New Orleans was designed to be a fortress against extreme weather. But it might be defeated by climate change.
  • It stands 18 feet above the ground on pillars with pilings that extend more than 100 feet underground. Its walls can withstand winds of up to 250 miles per hour.But the water is coming.
  • The assault from climate change is slower but more relentless than any storm, and will ultimately do more damage. It threatens researchers’ ability to study marine environments up close at a time when it’s more vital than ever to understand them.
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  • Fox Island Environmental Education Center, a Virginia institution that has opened up the wonders of the natural world to young people for more than 40 years, shut down in November. Between erosion and sea level rise, so much of the island’s salt marsh had disappeared that “it made it unsafe to run the program,” said Tom Ackerman, vice president for education at the Chesapeake Bay Foundation, which owns the island center.
  • Officials predict that, without action, the lab might need to shut down several dozen days each year within the next 10 to 15 years. The corrosive saltwater attacks the structure and has risen up through the soil into buried electrical cables, at one point causing a blackout. Some floods are accompanied by droves of fiddler crabs that sometimes find their way into the elevators.
  • because south Louisiana’s land is subsiding while the oceans are rising, the region has what may be the highest relative sea level rise in the country. “We’re just 10 to 30 years in front of the curve of everybody else,” he said.
  • Many marine labs are preparing to meet similar challenges, though they are in locations that are not yet facing the level of threat that Louisiana is.
  • At the Louisiana center, Ms. Conover sees educational value in their problems. Along with its mission as a scientific research facility, it is also a center for environmental education with visits from some 5,000 students each year. “If our parking lot is flooding when a group is here, we definitely talk about why we’re flooding on that given day, when five years ago we wouldn’t, given the same conditions.” That example, she said, “gives the perspective of what our coastal communities are dealing with.”
  • “Global sea-level rise is one of the greatest challenges facing society in the 21st century, and understanding how this phenomenon impacts coastal systems, infrastructure and the people who use them requires a regular coastal presence.”
krystalxu

communication - The psychology of communication | social behaviour | Britannica.com - 0 views

  • individuals are indeed variably persuasible and that, at times, factors of personality are related to this quality.
  • The dissonant or inconsistent elements include the bowler’s knowledge of his skill and the fact of his poor score. This produces tension.
  • Because the agreement or disagreement of a communication with an individual’s cognitive structure affects not only behaviour but perception as well, the major criterion for the psychological analysis of communication is neither the message nor the medium but the expectation of the person receiving the message.
krystalxu

Developing Communication Language And Literacy Skills Education Essay - 0 views

  • They need to recognise the role of communication in our society and from birth they need many and varied opportunities for positive interaction, and responses to their attempts to express themselves.
  • Communication, Language and Literacy helps a child to understand relationships, to hear words and sentences.
  • Through their growing knowledge and understanding, children can learn to appreciate the contribution made by many cultures to the development and application of communication, language and literacy.
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  • Children learn different communication, language and literacy skills through a structure of literacy framework that are related to development.
  • The process tries to make children to enjoy communication, language and literacy and be enthusiastic about the learning it .
  • They develop understanding of the correspondence between spoken and written sounds and learn to link sounds and letters and use their knowledge to read and write simple words by sounding out and blending.
  • The development of a national infrastructure is capable of providing ongoing professional development, quality assurance and data collection for the intervention.
  • The observations should be shared with the group to help make improvements in future performances.
  • Observing and encouraging babies and children's use of mirrors for self exploration of facial expression and gesture.
  • At times it can be useful to encourage children to use their home language, for example when organising initial ideas.
  • New buildings should be physically accessible to disabled pupils and will involve improving access to existing buildings including ramps, wider doors, low sinks, etc
  • All opportunities need to be well grounded in positive pride for the styles common in every child's own background. 
manhefnawi

Learning to Read as an Adult Changes Deep Regions of the Brain | Mental Floss - 0 views

  • In the evolutionary history of humans, reading and writing are relatively new functions. As a result, in order to read written language, human brains have had to recruit and adapt parts of the visual system to interface with language centers. This is a process researchers have long believed occurred primarily in the cerebral cortex, the outer layer of the brain. But in a new study where illiterate people in their thirties were trained to read over six months, researchers have discovered that reading actually activates much deeper brain structures as well, opening doors to a better understanding of how we learn, and possible new interventions for dyslexia. Their results were recently published in the journal Science Advances.
krystalxu

Consciousness and Language | Psychology Today - 0 views

  • Homo sapiens became sapiens largely because of language.
  • We can call this problem the radically uneven distribution of language.
  • If one conceives of consciousness as access to our thoughts for action and report—the so-called ‘access consciousness’ (Block, 1995
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  • related to our ability to have very complex interactions with our environment and with others.
  • ) determining how a semantics based on behavior and goals is capable of explaining the inferential and hierarchical structure of sentences, which is basic for language comprehension;
  • If one holds the view that phenomenal consciousness does not play any role (that it, as it were, just “sits there” in us) then one commits to a kind of epiphenomenalist view (that consciousness is just a by-product of cognitive processing with no meaningful purpose).
krystalxu

Psychology and Sociology - What is the Difference? » Degree in Sociology - 0 views

  • Sociology looks beyond individuals and examines societies through the specific lenses or associations.
  • People with a background in sociology can work in these specific positions and more:
  • While it is interesting to note all the places that they overlap – eventual deductions about the behaviors of people, humanity, societal structures – they are also very different and attract different kinds of people to each of their disciplines.
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  • Both help people understand the dynamics of emotions, relationships and behaviors better.
krystalxu

Philosophy/Sociology (BA) - Undergraduate, University of York - 0 views

  • In Sociology, you will be introduced to core elements of the subject, including sociological methodology and key concepts.
  • These will help you to develop the knowledge, understanding, and skills that you'll use in more specialised investigations in your third year.
  • Course structure may vary in future years.
katherineharron

Biden says Democrats have 'had enough debates' after Sanders commits to April showdown ... - 0 views

  • oe Biden said Wednesday that Democrats have "had enough" debates, suggesting he is unwilling to have another one-on-one showdown with Vermont Sen. Bernie Sanders.
  • "If there is a debate in April, he plans to be there," Sanders communications director Mike Casca said Tuesday.
  • "I think we need a good debate as to where we go, not only just now but in the future," Sanders told Cooper. "And to my mind, if there's anything that this unexpected moment in American history should teach us, we've got to rethink the basic structures of American society, and that is guaranteed health care to all as a human right, creating an economy that provides for all people not just the wealthy."
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  • But the pandemic has led some states to push their primaries into June, opening up the possibility that it could take more than two months for a candidate to cross the threshold needed to clinch the nomination.
blythewallick

Can Artificial Intelligence Be Creative? | JSTOR Daily - 0 views

  • Machines can write compelling ad copy and solve complex “real life” problems. Should the creative class be worried?
  • Rich breaks down some “abstract” problems into their fundamental parts and shows how, with comprehensive enough data and well-structured enough logical programming, AI could be suited to tackle creative problems. In one case, she offers a “real world” example about a manufacturing company’s new line of products and their plans, goals, and expectations for marketing the new line to a specific city. Weekly Newsletter Get your fix of JSTOR Daily’s best stories in your inbox each Thursday. Privacy Policy   Contact Us You may unsubscribe at any time by clicking on the provided link on any marketing message.
  • almost all problems rely (or ought to rely) on an understanding of the nature of both knowledge and reasoning. Humanists are trying to solve many of these same problems. Thus there is room for a good deal of interaction between artificial intelligence and many disciplines within the humanities.
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  • There is much to be said, however, for art’s ability to evoke emotion based on common experience, sincerity, talent, and unique skill. Rich proves that AI can be used to answer complicated questions. But what we think of as creative work in the humanities is much more often about asking questions than it is about answering them.
blythewallick

Other People Probably Like You More Than You Think They Do | Psychology Today - 0 views

  • They performed several studies that had a similar structure. In these studies, strangers had a brief conversation (ranging in length from five minutes to 45 minutes). Afterward, the participants rated how much they liked their conversation partner as well as how much they thought their conversation partner would like them.
  • On the one hand, people’s predictions of how much people would like them were pretty good. In general, if you thought that the other person would like you (or would not), you were just about right. On the other hand, people also systematically underestimated how much other people would like them. That is their ratings of how much their conversation partner liked them were pessimistic. The researchers called this the liking gap.
  • Independent raters were able to predict how much a person liked their conversation partner by the way that person acted during the conversation. So, people could potentially get accurate information from their conversation partner about how much they are liked. They are just not using that information.
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  • This research suggests that you should probably give yourself the benefit of the doubt when you meet other people. Even if you feel like you had a bad conversation with them, chances are you made a favorable impression. Other people probably like you better than you think they do.
  • That also means that if you’re interested in meeting up with someone again, you should reach out. You might be pleasantly surprised to find out that the other person would like to hang out with you as well.
manhefnawi

Brain waves may focus attention and keep information flowing | Science News - 0 views

  • We can’t see it, but brains hum with electrical activity. Brain waves created by the coordinated firing of huge collections of nerve cells pinball around the brain. The waves can ricochet from the front of the brain to the back, or from deep structures all the way to the scalp and then back again.
krystalxu

Behavioral economics: Reunifying psychology and economics | Proceedings of the National... - 0 views

  • A recent approach, “behavioral economics,” seeks to use psychology to inform economics, while maintaining the emphases on mathematical structure and explanation of field data that distinguish economics from other social sciences (1–3).
sanderk

How Procrastination Affects Your Health - Thrive Global - 0 views

  • fine line between procrastination and being “pressure prompted.” If you’re like me and pressure prompted, you are someone who often does your best work when faced with a looming deadline. While being pressure prompted may entail a bit of procrastination, it is procrastination within acceptable limits. In other words, it is a set of conditions that offers just enough pressure to ensure you’re at the top of your game without divulging into chaos or most importantly, impacting other members of your team by preventing them from delivering their best work in a timely manner.
  • Procrastination is a condition that has consequences on one’s mental and physical health and performance at school and in the workplace.
  • Piers Steel defines procrastination as “a self-regulatory failure leading to poor performance and reduced well-being.” Notably, Steel further emphasizes that procrastination is both common (80% to 90% of college-age students suffer from it at least some of the time) and something most people (95%) wish to overcome.
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  • Steel even argues that procrastination may now be on the rise as people increasingly turn to the immediate gratification made possible by information technologies and specifically, social media platforms.
  • for a small percentage of people, procrastination isn’t just a temporary or occasional problem but rather something that comes to structure their lives and ultimately limit their potential.
  • In a 2008 study, Peter Gröpel & Piers Steel investigated predictors of procrastination in a large Internet-based study that included over 9,000 participants. Their results revealed two important findings. First, their results showed that goal setting reduced procrastination; second, they found that it was strongly associated with lack of energy.
  • While it is true that intrinsically motivated people may have an easier time getting into flow, anyone, even a chronic procrastinator, can cultivate flow. The first step is easy—it simply entails coming up with a clear goal.
  • The second step is to stop feeling ashamed about your procrastinating tendencies.
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    This article is very interesting because it says that procrastination is not necessarily bad. Procrastination can be good for people in small quantities because it causes them to be pressured into actually doing their work. However, there is a point where procrastination becomes an issue. I find it interesting how phones and computers have caused procrastination problems to become more severe. Phones and computers can give people instant gratification which leads to more procrastination. As the article says if people set goals for themselves and are disciplined they can overcome procrastination.
Javier E

A New Alternative to Dark Matter - The Atlantic - 0 views

  • The challenges for alternative gravity theories—collectively known as modified Newtonian dynamics, or MOND—were spelled out in a separate preprint coincidentally published the day after the new model appeared. Chief among them is recasting the leading role dark matter plays in drawing the universe together, as described by a well-established cosmological model known as LCDM, or Lambda cold dark matter.
  • Simply put, LCDM says that we wouldn’t be here without dark matter. The infant universe was so smooth that the gravitational attraction of ordinary matter alone wouldn’t have been enough to gather particles into galaxies, stars, and planets. Enter dark-matter particles. Under the LCDM model, their collective bulk sculpts normal matter into the modern cosmic structures studied by astronomers.
  • LCDM became the standard model of cosmology in part because it so precisely agrees with the CMB. This map of the early universe shows almost imperceptibly thick and thin spots rippling through the cosmos. More recently, researchers have been able to measure the orientation or polarization of the CMB’s light more precisely. Any successful cosmology will need to establish a comprehensive history of the cosmos by reproducing these three observations: the CMB’s temperature, the CMB’s polarization, and the current distribution of galaxies and galaxy clusters.
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  • Recreating these and other features without LCDM’s titular ingredient, Spergel showed, requires the finest of theoretical needle threading. “We haven’t disproven the existence of all these [modified-gravity theories],” he says. “But any alternative theory has to jump through these hoops.”
  • Złosnik and Skordis believe they’ve done just that—although in a way that might surprise MOND skeptics and fans alike. They managed to construct a theory of gravity that contains an ingredient that acts exactly like an invisible form of matter on cosmic scales, blurring the line between the dark matter and MOND paradigms.
  • Their theory, dubbed RelMOND, adds to the equations of general relativity an omnipresent field that behaves differently in different arenas. On the grandest scales, where the universe noticeably stretches as it expands, the field acts like invisible matter. In this mode, which Złosnik calls “dark dust,” the field could have shaped the visible universe just as dark matter would
  • RelMOND “cannot do worse than LCDM,” says Złosnik, who notes that it very closely mimics that theory for the universe as a whole.
  • But if we zoom in on a galaxy, where the fabric of space holds rather still, the field acts in a way that’s true to its MOND roots: It entwines itself with the standard gravitational field, beefing it up just enough to hold a galaxy together without extra matter
  • (The researchers aren’t yet sure how the field acts for larger clusters of galaxies, a perennial MOND sore spot. They suggest that this intermediate scale might be a good place to look for observational clues that could set the theory apart.)
  • Despite this mathematical achievement by Złosnik and Skordis, dark matter remains the simpler theory. Constructing the new field takes four new moving mathematical parts, while LCDM handles dark matter with just one. Hooper likens the situation to a detective debating whether a person at a murder scene is the murderer or has been framed by the CIA. Even if the available evidence matches both theories, one requires less of a leap.
Javier E

Covid-19 expert Karl Friston: 'Germany may have more immunological "dark matter"' | Wor... - 0 views

  • Our approach, which borrows from physics and in particular the work of Richard Feynman, goes under the bonnet. It attempts to capture the mathematical structure of the phenomenon – in this case, the pandemic – and to understand the causes of what is observed. Since we don’t know all the causes, we have to infer them. But that inference, and implicit uncertainty, is built into the models
  • That’s why we call them generative models, because they contain everything you need to know to generate the data. As more data comes in, you adjust your beliefs about the causes, until your model simulates the data as accurately and as simply as possible.
  • A common type of epidemiological model used today is the SEIR model, which considers that people must be in one of four states – susceptible (S), exposed (E), infected (I) or recovered (R). Unfortunately, reality doesn’t break them down so neatly. For example, what does it mean to be recovered?
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  • SEIR models start to fall apart when you think about the underlying causes of the data. You need models that can allow for all possible states, and assess which ones matter for shaping the pandemic’s trajectory over time.
  • These techniques have enjoyed enormous success ever since they moved out of physics. They’ve been running your iPhone and nuclear power stations for a long time. In my field, neurobiology, we call the approach dynamic causal modelling (DCM). We can’t see brain states directly, but we can infer them given brain imaging data
  • Epidemiologists currently tackle the inference problem by number-crunching on a huge scale, making use of high-performance computers. Imagine you want to simulate an outbreak in Scotland. Using conventional approaches, this would take you a day or longer with today’s computing resources. And that’s just to simulate one model or hypothesis – one set of parameters and one set of starting conditions.
  • Using DCM, you can do the same thing in a minute. That allows you to score different hypotheses quickly and easily, and so to home in sooner on the best one.
  • This is like dark matter in the universe: we can’t see it, but we know it must be there to account for what we can see. Knowing it exists is useful for our preparations for any second wave, because it suggests that targeted testing of those at high risk of exposure to Covid-19 might be a better approach than non-selective testing of the whole population.
  • Our response as individuals – and as a society – becomes part of the epidemiological process, part of one big self-organising, self-monitoring system. That means it is possible to predict not only numbers of cases and deaths in the future, but also societal and institutional responses – and to attach precise dates to those predictions.
  • How well have your predictions been borne out in this first wave of infections?For London, we predicted that hospital admissions would peak on 5 April, deaths would peak five days later, and critical care unit occupancy would not exceed capacity – meaning the Nightingale hospitals would not be required. We also predicted that improvements would be seen in the capital by 8 May that might allow social distancing measures to be relaxed – which they were in the prime minister’s announcement on 10 May. To date our predictions have been accurate to within a day or two, so there is a predictive validity to our models that the conventional ones lack.
  • What do your models say about the risk of a second wave?The models support the idea that what happens in the next few weeks is not going to have a great impact in terms of triggering a rebound – because the population is protected to some extent by immunity acquired during the first wave. The real worry is that a second wave could erupt some months down the line when that immunity wears off.
  • the important message is that we have a window of opportunity now, to get test-and-trace protocols in place ahead of that putative second wave. If these are implemented coherently, we could potentially defer that wave beyond a time horizon where treatments or a vaccine become available, in a way that we weren’t able to before the first one.
  • We’ve been comparing the UK and Germany to try to explain the comparatively low fatality rates in Germany. The answers are sometimes counterintuitive. For example, it looks as if the low German fatality rate is not due to their superior testing capacity, but rather to the fact that the average German is less likely to get infected and die than the average Brit. Why? There are various possible explanations, but one that looks increasingly likely is that Germany has more immunological “dark matter” – people who are impervious to infection, perhaps because they are geographically isolated or have some kind of natural resistance
  • Any other advantages?Yes. With conventional SEIR models, interventions and surveillance are something you add to the model – tweaks or perturbations – so that you can see their effect on morbidity and mortality. But with a generative model these things are built into the model itself, along with everything else that matters.
  • Are generative models the future of disease modelling?That’s a question for the epidemiologists – they’re the experts. But I would be very surprised if at least some part of the epidemiological community didn’t become more committed to this approach in future, given the impact that Feynman’s ideas have had in so many other disciplines.
Javier E

How the leading coronavirus vaccines made it to the finish line - The Washington Post - 0 views

  • If, as expected in the next few weeks, regulators give those vaccines the green light, the technology and the precision approach to vaccine design could turn out to be the pandemic’s silver linings: scientific breakthroughs that could begin to change the trajectory of the virus this winter and also pave the way for highly effective vaccines and treatments for other diseases.
  • Vaccine development typically takes years, even decades. The progress of the last 11 months shifts the paradigm for what’s possible, creating a new model for vaccine development and a toolset for a world that will have to fight more never-before-seen viruses in years to come.
  • Long before the pandemic, Graham worked with colleagues there and in academia to create a particularly accurate 3-D version of the spiky proteins that protrude from the surface of coronaviruses — an innovation that was rejected for publication by scientific journals five times because reviewers questioned its relevance.
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  • Messenger RNA is a powerful, if fickle, component of life’s building blocks — a workhorse of the cell that is also truly just a messenger, unstable and prone to degrade.
  • . In 1990,
  • That same year, a team at the University of Wisconsin startled the scientific world with a paper that showed it was possible to inject a snippet of messenger RNA into mice and turn their muscle cells into factories, creating proteins on demand.
  • If custom-designed RNA snippets could be used to turn cells into bespoke protein factories, messenger RNA could become a powerful medical tool. It could encode fragments of virus to teach the immune system to defend against pathogens. It could also create whole proteins that are missing or damaged in people with devastating genetic diseases, such as cystic fibrosis.
  • In 2005, the pair discovered a way to modify RNA, chemically tweaking one of the letters of its code, so it didn’t trigger an inflammatory response. Deborah Fuller, a scientist who works on RNA and DNA vaccines at the University of Washington, said that work deserves a Nobel Prize.
  • messenger RNA posed a bigger challenge than other targets.“It’s tougher — it’s a much bigger molecule, it’s much more unstable,”
  • Unlike fields that were sparked by a single powerful insight, Sahin said that the recent success of messenger RNA vaccines is a story of countless improvements that turned an alluring biological idea into a beneficial technology.
  • “This is a field which benefited from hundreds of inventions,” said Sahin, who noted that when he started BioNTech in 2008, he cautioned investors that the technology would not yield a product for at least a decade. He kept his word: Until the coronavirus sped things along, BioNTech projected the launch of its first commercial project in 2023.
  • “It’s new to you,” Fuller said. “But for basic researchers, it’s been long enough. . . . Even before covid, everyone was talking: RNA, RNA, RNA.”
  • All vaccines are based on the same underlying idea: training the immune system to block a virus. Old-fashioned vaccines do this work by injecting dead or weakened viruses
  • ewer vaccines use distinctive bits of the virus, such as proteins on their surface, to teach the lesson. The latest genetic techniques, like messenger RNA, don’t take as long to develop because those virus bits don’t have to be generated in a lab. Instead, the vaccine delivers a genetic code that instructs cells to build those characteristic proteins themselves.
  • They wanted the immune system to learn to recognize the thumb tack spike, so McLellan tasked a scientist in his laboratory with identifying genetic mutations that could anchor the protein into the right configuration. It was a painstaking process for Nianshuang Wang, who now works at a biotechnology company, Regeneron Pharmaceuticals. After trying hundreds of genetic mutations, he found two that worked. Five journals rejected the finding, questioning its significance, before it was published in 2017.
  • That infection opened Graham’s eyes to an opportunity. HKU1 was merely a nuisance, as opposed to a deadly pneumonia; that meant it would be easier to work with in the lab, since researchers wouldn’t have to don layers of protective gear and work in a pressurized laboratory.
  • Severe acute respiratory syndrome had emerged in 2003. Middle East respiratory syndrome (MERS) broke out in 2012. It seemed clear to Graham and Jason McLellan, a structural biologist now at the University of Texas at Austin, that new coronaviruses were jumping into people on a 10-year-clock and it might be time to brace for the next one.
  • Last winter, when Graham heard rumblings of a new coronavirus in China, he brought the team back together. Once its genome was shared online by Chinese scientists, the laboratories in Texas and Maryland designed a vaccine, utilizing the stabilizing mutations and the knowledge they had gained from years of basic research — a weekend project thanks to the dividends of all that past work.
  • Graham needed a technology that could deliver it into the body — and had already been working with Moderna, using its messenger RNA technology to create a vaccine against a different bat virus, Nipah, as a dress rehearsal for a real pandemic. Moderna and NIH set the Nipah project aside and decided to go forward with a coronavirus vaccine.
  • On Jan. 13, Moderna’s Moore came into work and found her team already busy translating the stabilized spike protein into their platform. The company could start making the vaccine almost right away because of its experience manufacturing experimental cancer vaccines, which involves taking tumor samples and developing personalized vaccines in 45 days.
  • At BioNTech, Sahin said that even in the early design phases of its vaccine candidates, he incorporated the slight genetic changes designed in Graham’s lab that would make the spike look more like the real thing. At least two other companies would incorporate that same spike.
  • If all goes well with regulators, the coronavirus vaccines have the makings of a pharmaceutical industry fairy tale. The world faced an unparalleled threat, and companies leaped into the fight. Pfizer plowed $2 billion into the effort. Massive infusions of government cash helped remove the financial risks for Moderna.
  • But the world will also owe their existence to many scientists outside those companies, in government and academia who pursued ideas they thought were important even when the world doubted them
  • Some of those scientists will receive remuneration, since their inventions are licensed and integrated into the products that could save the world.
  • As executives become billionaires, many scientists think it is fair to earn money from their inventions that can help them do more important work. But McLellan’s laboratory at the University of Texas is proud to have licensed an even more potent version of their spike protein, royalty-free, to be incorporated into a vaccine for low and middle income countries.
  • “They’re using the technology that [Kariko] and I developed,” he said. “We feel like it’s our vaccine, and we are incredibly excited — at how well it’s going, and how it’s going to be used to get rid of this pandemic.”
  • “People hear about [vaccine progress] and think someone just thought about it that night. The amount of work — it’s really a beautiful story of fundamental basic research,” Fauci said. “It was chancy, in the sense that [the vaccine technology] was new. We were aware there would be pushback. The proof in the pudding is a spectacular success.”
  • The Vaccine Research Center, where Graham is deputy director, was the brainchild of Anthony S. Fauci, director of the National Institute of Allergy and Infectious Diseases. It was created in 1997 to bring together scientists and physicians from different disciplines to defeat diseases, with a heavy focus on HIV.
  • the pandemic wasn’t a sudden eureka moment — it was a catalyst that helped ignite lines of research that had been moving forward for years, far outside the spotlight of a global crisis.
Javier E

The Real Reason You and Your Neighbor Make Different Covid-19 Risk Decisions - WSJ - 0 views

  • Personality traits that are shaped by genetics and early life experiences strongly influence our Covid-19-related decisions, studies from the U.S. and Japan have found.
  • In a study of more than 400 U.S. adults, Dr. Byrne and her colleagues found that how people perceive risks, whether they make risky decisions, and their preference for immediate or delayed rewards were the largest predictors of whether they followed public-health guidelines when it came to wearing masks and social distancing.
  • These factors accounted for 55% of the difference in people’s behaviors—more than people’s political affiliation, level of education or age.
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  • Dr. Byrne and her colleagues measured risky decision-making by presenting people with a gambling scenario. They could choose between two bets: One offered a guaranteed amount of money, while the other offered the possibility of a larger amount of money but also the possibility of receiving no cash. A different exercise measured people’s preference for immediate versus delayed rewards: Participants could choose a certain amount of money now, or a larger amount later.
  • Study subjects also reported Covid-19 precautions they had taken in their daily lives, including masking and social distancing.
  • with Covid-19, people don’t feel sick immediately after an exposure so the benefits of wearing a mask, social distancing or getting vaccinated aren’t immediately apparent. “You don’t see the lives you potentially save,” she says
  • “People generally are more motivated by immediate gratification or immediate benefits rather than long-term benefits, even when the long-term benefits are much greater,
  • Research has also found being extroverted or introverted affects how people make decisions about Covid-19 precautions. A recent study of more than 8,500 people in Japan published in the journal PLOS One in October 2020 found that those who scored high on a scale of extraversion were 7% less likely to wear masks in public and avoid large gatherings, among other precautions.
  • The study also found that people who scored high on a measure of conscientiousness—valuing hard work and achievement—were 31% more likely to follow Covid-19 public-health precautions.
  • Scientists believe that a person’s propensity to take risks is partly genetic and partly the result of early life experiences
  • Certain negative childhood experiences including physical, emotional or sexual abuse, parental divorce, or living with someone who was depressed or abused drugs or alcohol are linked to risky behavior in adulthood like smoking and drinking heavily, other research has found.
  • Studies of twins have generally found that about 30% of the difference in individual risk tolerance is genetic
  • And scientists have discovered that the brains of people who are more willing to take risks look different than those of people who are more cautious.
  • ambling task had differences in the structure and function of the amygdala, a part of the brain involved in detecting threats, and the prefrontal cortex, a region involved in executive
  • Even people who have the same information and a similar perception of the risks may make different decisions because of the ways they interpret the information. When public-health officials talk about breakthrough infections in vaccinated individuals being rare, for example, “rare means different things” to different people
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