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Norway’s experience doesn’t mean that younger, healthier people should avoid being vaccinated.

Official reports of allergic reactions have been rare as governments rush to roll out vaccines to try to contain the global pandemic.

All the reported deaths related to “elderly people with serious basic disorders,”

The first people to be immunized in many places have been older than that as countries rush to inoculate nursing-home residents at high risk from the virus.

for those with the most severe frailty, even relatively mild vaccine side effects can have serious consequences. For those who have a very short remaining life span anyway, the benefit of the vaccine may be marginal or irrelevant.

This does not mean that there is a causal link between vaccination and death.

Will Wright, inventor of bestselling “The Sims” videogame series, heaps similar praise.  “Montessori taught me the joy of discovery,” Mr. Wright said, “It’s all about learning on your terms, rather than a teacher explaining stuff to you.  SimCity comes right out of Montessori…”

Hal Gregersen of globe-spanning business school INSEAD surveyed over 3,000 executives and interviewed 500 people who had either started innovative companies or invented new products.

being self-motivated, questioning what’s going on in the world, doing things a little bit differently.”

most highly creative achievers don’t begin with brilliant ideas, they discover them.

We can change the way we’ve been trained to think.  That begins in small, achievable ways, with increased experimentation and inquisitiveness. 

The genes of the oldest known residents of the Caribbean link them with the earliest populations that settled in Central and South America.

Part of the problem is that scientists have yet to find ancient DNA in the Caribbean that is more than 3,000 years old

The other problem is that ancient DNA is still scarce on the Caribbean coast of the mainland.

About 2,500 years ago, the archaeological record shows, there was a drastic shift in the cultural life of the Caribbean. People started living in bigger settlements, intensively farming crops like maize and sweet potatoes. Their pottery became more sophisticated and elaborate. For archaeologists, the change indicates the end of what they call the Archaic Age and the start of a Ceramic Age.

The skeletons from the Ceramic Age largely shared a new genetic signature. Their DNA links them to small tribes still living today in Colombia and Venezuela.

We don’t know a lot about these languages, although some words have managed to survive. Hurricane, for example, comes from hurakán, the Taino name for the god of storms.

The people bearing Ceramic Age ancestry came to dominate the Caribbean, with almost no interbreeding between the two groups.

These words bear a striking resemblance to words from a family of languages in South America called Arawak. The DNA of the Ceramic Age Caribbeans most closely resembles that of living Arawak speakers.

the new DNA findings had surprised him in many ways, giving him a host of new questions to investigate.

Over the course of the Ceramic Age, for example, strikingly new pottery styles emerged every few centuries. Researchers have long guessed that those shifts reflect the arrival of new groups of people in the islands. The ancient DNA doesn’t support that idea, though. There’s a genetic continuity through those drastic cultural changes. It appears that the same group of people in the Caribbean went through a series of major social changes that archaeologists have yet to explain.

Dr. Reich and his fellow geneticists also discovered family ties that spanned the Caribbean during the Ceramic Age. They found 19 pairs of people on different islands who shared identical segments of DNA — a sign that they were fairly close relatives. In one case, they found long-distance cousins from the Bahamas and Puerto Rico, separated by over 800 miles.

“The original idea was that people start in one place, they establish a colony someplace else, and then they just cut all ties to where they came from,” Dr. Keegan said. “But the genetic evidence is suggesting that these ties were maintained over a long period of time.”

Rather than being made up of isolated communities, in other words, the Caribbean was a busy, long-distance network that people regularly traveled by dugout canoe. “The water is like a highway,”

The genetic variations also allowed Dr. Reich and his colleague to estimate the size of the Caribbean society before European contact. Christopher Columbus’s brother Bartholomew sent letters back to Spain putting the figure in the millions

The DNA suggests that was an exaggeration: the genetic variations imply that the total population was as low as the tens of thousands.

now, with a population of about 44 million people, the Caribbean may contain more Taino DNA than it did in 1491.

Dr. Aviles and his colleagues have uploaded the ancient Caribbean genomes to a genealogical database called GEDMatch. With the help of genealogists, people can compare their own DNA to the ancient genomes. They can see the matching stretches of genetic material that reveal their relatedness.

The Yale-led study investigated the timing of this outgassing by modeling the effects of carbon dioxide and sulfur emissions on global temperatures and comparing them with paleotemperature records spanning the extinction. They found that at least 50% or more of the major outgassing from the Deccan Traps occurred well before the asteroid impact, and only the impact coincided with the mass extinction event.The volcanoes did "cause a warming event," but its effect had gone by the time extinction happened, said Michael Henehan, a former researcher at Yale who is now based at the GFZ German Research Centre for Geosciences.

“I have long been interested in classifications of people, in how they affect the people classified, and how the effects on the people in turn change the classifications,” he wrote in “Making Up People

His work in the philosophy of science was groundbreaking: He departed from the preoccupation with questions that had long concerned philosophers. Arguing that science was just as much about intervention as it was about representation, be helped bring experimentation to center stage.

Regarding one such question — whether unseen phenomena like quarks and electrons were real or merely the theoretical constructs of physicists — he argued for reality in the case of phenomena that figured in experiments, citing as an example an experiment at Stanford that involved spraying electrons and positrons into a ball of niobium to detect electric charges. “So far as I am concerned,” he wrote, “if you can spray them, they’re real.”

His book “The Emergence of Probability” (1975), which is said to have inspired hundreds of books by other scholars, examined how concepts of statistical probability have evolved over time, shaping the way we understand not just arcane fields like quantum physics but also everyday life.

“I was trying to understand what happened a few hundred years ago that made it possible for our world to be dominated by probabilities,” he said in a 2012 interview with the journal Public Culture. “We now live in a universe of chance, and everything we do — health, sports, sex, molecules, the climate — takes place within a discourse of probabilities.”

Whatever the subject, whatever the audience, one idea that pervades all his work is that “science is a human enterprise,” Ragnar Fjelland and Roger Strand of the University of Bergen in Norway wrote when Professor Hacking won the Holberg Prize. “It is always created in a historical situation, and to understand why present science is as it is, it is not sufficient to know that it is ‘true,’ or confirmed. We have to know the historical context of its emergence.”

Hacking often argued that as the human sciences have evolved, they have created categories of people, and that people have subsequently defined themselves as falling into those categories. Thus does human reality become socially constructed.

In 2000, he became the first Anglophone to win a permanent position at the Collège de France, where he held the chair in the philosophy and history of scientific concepts until he retired in 2006.

“I call this the ‘looping effect,’” he added. “Sometimes, our sciences create kinds of people that in a certain sense did not exist before.”

In “Why Race Still Matters,” a 2005 article in the journal Daedalus, he explored how anthropologists developed racial categories by extrapolating from superficial physical characteristics, with lasting effects — including racial oppression. “Classification and judgment are seldom separable,” he wrote. “Racial classification is evaluation.”

Similarly, he once wrote, in the field of mental health the word “normal” “uses a power as old as Aristotle to bridge the fact/value distinction, whispering in your ear that what is normal is also right.”

In his influential writings about autism, Professor Hacking charted the evolution of the diagnosis and its profound effects on those diagnosed, which in turn broadened the definition to include a greater number of people.

Encouraging children with autism to think of themselves that way “can separate the child from ‘normalcy’ in a way that is not appropriate,” he told Public Culture. “By all means encourage the oddities. By no means criticize the oddities.”

His emphasis on historical context also illuminated what he called transient mental illnesses, which appear to be so confined 0cto their time 0c 0cthat they can vanish when times change.

“hysterical fugue” was a short-lived epidemic of compulsive wandering that emerged in Europe in the 1880s, largely among middle-class men who had become transfixed by stories of exotic locales and the lure of trave

His intellectual tendencies were unmistakable from an early age. “When he was 3 or 4 years old, he would sit and read the dictionary,” Jane Hacking said. “His parents were completely baffled.”

He wondered aloud, the interviewer noted, if the whole universe was governed by nonlocality — if “everything in the universe is aware of everything else.”“That’s what you should be writing about,” he said. “Not me. I’m a dilettante. My governing word is ‘curiosity.’”

Above all, the manual emphasized efficiency. Managers were told to answer DMs in less than five minutes, since users were coming to OnlyFans for immediate gratification and would go elsewhere if ignored. It encouraged the creation of keyboard shortcuts, so that managers could deploy an arsenal of rote sexual phrases with a few keystrokes, steering conversations toward the hard sell. It also outlined a series of strategies to boost engagement on the pages, including a gambit in which models would offer to rate a picture of a subscriber’s penis for a fee.

“Every page needs to have an established back story to make the person seem more believable,” it stated. OnlyFans works because people pay for a connection that feels deeper than porn. The document encouraged Ekko’s employees, called page managers, to identify “big spenders” who would part ways with more than $200 in short order, and cultivate a deep rapport by asking about their life and what they do for a living.

This can be extremely time-consuming: In an interview with this magazine last year, an OnlyFans creator said she spends six hours a day just sexting with subscribers. But these relationships are important to cultivate. In a blog post on its website, OnlyFans encourages creators to cater to their “superfans,” who pay for custom content and will “give more if they feel they’re getting something special.”

But all of them take advantage of the same raw materials: the endless reproducibility of digital images; the widespread global availability of cheap English-speaking labor; and the world’s unquenchable desire for companionship.

The key to this business model is the ready availability of cheap English-speaking labor around the globe. Job postings for OnlyFans chatters are widespread on freelance sites like Upwork, many offering as little as $3 an hour. Agency heads told me they’ve hired workers from Eastern Europe, Africa and all across Southeast Asia. “At the end of the day, it is a geo-arbitrage business,”

This phenomenon is part of a broader boom in homespun online businesses that connect cheap developing-world labor with American consumers, allowing the proprietor to step back and reap the profits

During his stint as a chatter, Andre has become intimately familiar with the quirks and desires of the subscribers. Over time, he’s learned something of a sex-work cliché: More than sexual gratification, he said, many of the guys just want someone to talk to