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these guys finally did what needed to be done to take a real stab at merging imaging and genomics

Brain imaging studies are expensive and, as a result, far too small to reliably tease out the effects of common gene variations. These effects tend to be tiny, for one thing, and difficult to distinguish from the background “noise” of other influences. And brain imaging is notoriously noisy: not only does overall brain size vary from person to person, for instance, but so do the sizes of specialized brain regions like the hippocampus, which is critical for memory formation.

persuaded research centers around the world to pool their resources and create one large database. It included genetic and extensive brain imaging results from about 21,000 people. The team then analyzed the collective data to see whether any genes were linked to brain structure.

The fact that many of our self-protective delusions are built into the way the brain works is no justification for not trying to override them. Knowing how dissonance works helps us identify our own inclinations to perpetuate errors -- and protect ourselves from those who can’t. Or won’t.Related LinksWhat Historians Can Learn from the Social Sciences and Sciences /* * * CONFIGURATION VARIABLES: EDIT BEFORE PASTING INTO YOUR WEBPAGE * * */ var disqus_shortname = 'hnndev'; // required: replace example with your forum shortname /* * * DON'T EDIT BELOW THIS LINE * * */ (function() { var dsq = document.createElement('script'); dsq.type = 'text/javascript'; dsq.async = true; dsq.src = '//' + disqus_shortname + '.disqus.com/embed.js'; (document.getElementsByTagName('head')[0] || document.getElementsByTagName('body')[0]).appendChild(dsq); })(); Please enable JavaScript to view the comments powered by Disqus. News Breaking News Historians DC Breaking News Historians DC ‘Scottsboro Boys’ pardoned in Alabama ‘November 22, 1963’ U-Boat discovered off the coast of Indonesia Vatican publicly unveils bone fragments said to belong to St. Peter Pictured: the 'real site' of the Hanging Gardens of Babylon Historian: Taiwan can use WWII legacy to improve standing with China 'I Take Long Walks': The Emotional Lives of Holocaust Scholars Chinese historian: Xi Jinping a master of "neo-authoritarianism" History Comes to Life With Tweets From Past Celtic Paths, Illuminated by a Sundial try{for(var lastpass_iter=0; lastpass_iter < document.forms.length; lastpass_iter++){ var lastpass_f = document.forms[lastpass_iter]; if(typeof(lastpass_f.lpsubmitorig2)=="undefined"){ lastpass_f.lpsubmitorig2 = lastpass_f.submit; lastpass_f.submit = function(){ var form=this; var customEvent = document.createEvent("Event"); customEvent.initEvent("lpCustomEvent", true, true); var d = document.getElementById("hiddenlpsubmitdiv"); for(var i = 0; i < document.forms.length; i++){ if(document.forms[i]==form){ d.innerText=i; } } d.dispatchEvent(customEvent); form.lpsubmitorig2(); } } }}catch(e){}

at last, history has gotten into bed with psychological science, and it’s a happy match. History gives us the data of, in Barbara Tuchman’s splendid words, our march of folly -- repeated examples of human beings unable and unwilling to learn from mistakes, let alone to admit them. Cognitive science shows us why

Our brains, which have allowed us to travel into outer space, have a whole bunch of design flaws, which is why we have so much breathtaking bumbling here on Earth.

When you bring home the wrong color of paint from the hardware store, it may not be your foggy memory at fault

Flombaum and his colleagues conducted four experiments on four different groups of people.

while the human brain can distinguish between millions of colors, it has difficulty remembering specific shades.

insurers low-balled their prices in the early days of the Affordable Care Act in order to gain market share. But there is another reason: higher&nbsp;drug prices.&nbsp;Prescription drug spending increased 13.1% in 2015

ASCO dryly remarked that she could find no economic theory to explain how companies price their drugs.&nbsp;

First, pharmaceutical companies can advertise directly to patients in America, which helps ensure demand. Second, price increases have been largely invisible to both patients and their doctors, in part because health-insurance plans often shield buyers from the true costs of their drugs. Third, Medicare, the public-health programme for those aged 65 and older,&nbsp;is the country’s largest drug customer, yet it is not allowed to negotiate prices with drug companies—with predictable results.&nbsp; The new drugs war

Punctuation arouses strong feelings. You have probably come across the pen-wielding vigilantes who skulk around defacing movie posters and amending handwritten signs that advertise "Rest Room's" or "Puppy's For Sale." People fuss about punctuation not only because it clarifies meaning but also because its neglect appears to reflect wider social decline. And while the big social battles seem intractable, smaller battles over the use of the apostrophe feel like they can be won. Enlarge ImageClose Yet the status of this and other cherished marks has long been precarious. The story of punctuation is one of comings and goings.

How might punctuation now evolve? The dystopian view is that it will vanish. I find this conceivable, though not likely. But we can see harbingers of such change: editorial austerity with commas, the newsroom preference for the period over all other marks, and the taste for visual crispness. Though it is not unusual to hear calls for new punctuation, the marks proposed tend to cannibalize existing ones. In this vein, you may have encountered the interrobang , which signals excited disbelief. Such marks are symptoms of an increasing tendency to punctuate for rhetorical rather than grammatical effect. Instead of presenting syntactical and logical relationships, punctuation reproduces the patterns of speech.

Defenders of the apostrophe insist that it minimizes ambiguity, but there are few situations in which its omission can lead to real misunderstanding.

To the uninitiated, the Twitter message looks utterly banal and harmless: an image of a white van parked in a driveway under a flag-draped window, with pretty much the most straightforward description imaginable: "Image from #Rochester."

The subtext of this story is social class.

"Best explanation for my fellow Americans—a Congresswoman from Massachusetts sending a picture from South Carolina of a pickup truck with a shotgun rack sitting in front of a mobile home draped in the confederate (Stars and Bars) flag," one commenter offered. "Maybe add a car up on cinder blocks sitting in the yard."

DO harsh words lead to violent acts? At a moment when hate speech seems to be proliferating, it’s a question worth asking.

worry that heated anti-Muslim political rhetoric would spark an increase in attacks against Muslims.

Some claim that last month’s mass shooting in Colorado Springs was provoked by Carly Fiorina’s assertion that Planned Parenthood was “harvesting baby parts”; Mrs. Fiorina countered that language could not be held responsible for the deeds of a “deranged” man.

A variety of methods have been developed over the past few decades to allow mapping of the functioning human brain. Two basic classes of mapping technique have evolved: those that map (or localise) the underlying electrical activity of the brain; and those that map local physiological or metabolic consequences of altered brain electrical activity. Among the former are the non-invasive neural electromagnetic techniques of electroencephalography (EEG) and magnetoencephalography (MEG). These methods allow exquisite temporal resolution of neural processes (typically over a 10–100 ms time scale), but suffer from poor spatial resolution (between 1 and several centimetres). Functional MRI (fMRI) methods are in the second category. They can be made sensitive to the changes in regional blood perfusion, blood volume (for example, using injected magnetic resonance contrast agents), or blood oxygenation that accompany neuronal activity. Blood oxygenation level dependent (BOLD) fMRI, which is sensitive primarily to the last of these variables, allows an image spatial resolution that is of the order of a few millimetres, with a temporal resolution of a few seconds (limited by the haemodynamic response itself). An accessible and more detailed introduction to the technique than is possible in this brief review is found in a recent book.1

Methods such as positron emission tomography (PET) provide an absolute measure of tissue metabolism. In contrast, BOLD fMRI can at present be used only for determining relative signal intensity changes associated with different cognitive states during a single imaging session. The most time efficient approach for comparing brain responses in different states during the imaging experiment is the “block” design19 (fig 3). This design uses relatively long alternating periods (for example, 30 seconds), during each of which a discrete cognitive state is maintained. In the simplest form, there may only be two such states, which are alternated throughout the experiment in order to ensure that variations arising from fluctuations in scanner sensitivity, patient movement, or changes in attention have a similar impact on the signal responses associated with both states.

The researchers found that reasons for believing in conspiracy theories can be grouped into three categories: The desire for understanding and certainty The desire for control and security The desire to maintain a positive self-image

Seeking explanations for events is a natural human desire

We all harbor false beliefs, that is, things we believe to be true but in fact are not.

An online video, presented in three- and six-minute versions, shows a forensic sketch artist who is asked to draw a series of women based only on their descriptions. Seated at a drafting table with his back to his subject, the artist, Gil Zamora, asks the women a series of questions about their features. “Tell me about your chin,” he says in the soft voice reminiscent of a therapist’s. Crow’s feet, big jaws, protruding chins and dark circles are just some of the many physical features that women criticized about themselves. After he finishes a drawing of a woman, he then draws another sketch of the same woman, only this time it is based on how someone else describes her. The sketches are then hung side by side and the women are asked to compare them. In every instance, the second sketch is more flattering than the first.

The video, shot in a loft in San Francisco, has become a sensation online. The three-minute version has been viewed more than 7.5 million times on the Dove YouTube channel, and the version that is twice as long has been viewed more than 936,000 times.

Dove executives said the campaign resulted from company research that showed only 4 percent of women consider themselves beautiful.

Every culture ever studied has been found to make music, and among the oldest artistic objects known are slender flutes carved from mammoth bone some 43,000 years ago — 24,000 years before the cave paintings of Lascaux.

And though the survival value that music held for our ancestors may not be as immediately obvious as the power to recognize words, Dr. Rauschecker added, “music works as a group cohesive. Music-making with other people in your tribe is a very ancient, human thing to do.”

devised a radical new approach to brain imaging that reveals what past studies had missed. By mathematically analyzing scans of the auditory cortex and grouping clusters of brain cells with similar activation patterns, the scientists have identified neural pathways that react almost exclusively to the sound of music — any music. It may be Bach, bluegrass, hip-hop, big band, sitar or Julie Andrews. A listener may relish the sampled genre or revile it. No matter. When a musical passage is played, a distinct set of neurons tucked inside a furrow of a listener’s auditory cortex will fire in response.Other sounds, by contrast — a dog barking, a car skidding, a toilet flushing — leave the musical circuits unmoved.

“So, you want to be a dictator?”

Too bad you’re living in this century. “It is tougher to lead an authoritarian regime in the face of democratic ideals, free speech and globalized media.

Snyderwine puts forth complex mathematical formulas that show a dictator how to stay in power with cost-benefit analyses of revolutions that take into account factors like bribes and the number of active revolutionaries killed.

Art &amp; Design Books Film Ideas Music &amp; Performance TV &amp; Radio Food &amp; Drink Blog Return to: Home | Culture | Books The Joy of Secularism: 11 Essays for How We Live Now By George Levine Reviewed by Terry Eagleton - 22 June 2011 82 comments Print version Email a friend Listen RSS Misunderstanding what it means to be secular.

Societies become truly secular not when they dispense with religion but when they are no longer greatly agitated by it. It is when religious faith ceases to be a vital part of the public sphere

Christianity is certainly other-worldly, and so is any reasonably sensitive soul who has been reading the newspapers. The Christian gospel looks to a future transformation of the appalling mess we see around us into a community of justice and friendship, a change so deep-seated and indescribable as to make Lenin look like a Lib Dem.“This [world] is our home," Levine comments. If he really feels at home in this crucifying set-up, one might humbly suggest that he shouldn't. Christians and political radicals certainly don't.

many services that claim to offer that rarest of digital commodities — privacy — don’t really deliver. Read the fine print.

Snapchat’s privacy page explains that private images are stored on someone’s phone — and on its own servers. “Forensically, even after they are deleted,” Snapchat says, those images can be retrieved. Whisper’s privacy page says the company owns the intellectual property, both images and text, that people post; Whisper reserves the right to sell that stuff to third parties. And Telegram, while seemingly less innocuous with its claims, nonetheless leaves out something you might want to know: someone can just take a screenshot or picture of that “private” conversation.

Don’t have a smartphone yet? They still know where you are and where you’ve been. The American Civil Liberties Union released a report this year that found that technologies that let governments scan license plates are being used to build databases of vehicle locations across the United States.

Children who had not yet learned to read and write were presented with a letter or a shape on an index card and asked to reproduce it in one of three ways: trace the image on a page with a dotted outline, draw it on a blank white sheet, or type it on a computer. They were then placed in a brain scanner and shown the image again.

When children had drawn a letter freehand, they exhibited increased activity in three areas of the brain that are activated in adults when they read and write

By contrast, children who typed or traced the letter or shape showed no such effect. The activation was significantly weaker.

the new media flatter us with attention—with our own personal ring tones and media feeds. Everything is addressed to us.

the public sphere has hollowed out the private sphere. People no longer defend the solid, private domain that is one’s own from the onrush of images and sensation. Instead, the self becomes liquid, a series of presented images. “The harder one tries to experiment with successive tentative approaches and to laboriously patch up successive public images, the less likely seems the prospect of reaching the self-assurance and self-confidence whose promise triggered all those exertions.”

Contemporary life is moodiness, the immediate feeling of the moment. Experience no longer comes tinged with feeling; it comes as feeling and often, it seems, without regard to its cognitive and/or active content.”

Babies' memory develops while napping: study For babies, the best time to learn something is right before a nap of at least 30 minutes, according to a new study. (ambrozinio/shuttersto

babies

Naps during the day of at least a half hour help infants retain new behaviors learned earlier, according to researchers from the University of Sheffield

Skinner's approach stressed the historical associations between a stimulus and the animal's response -- an approach easily framed as a kind of empirical statistical analysis, predicting the future as a function of the past.

Chomsky's conception of language, on the other hand, stressed the complexity of internal representations, encoded in the genome, and their maturation in light of the right data into a sophisticated computational system, one that cannot be usefully broken down into a set of associations.

Chomsky acknowledged that the statistical approach might have practical value, just as in the example of a useful search engine, and is enabled by the advent of fast computers capable of processing massive data. But as far as a science goes, Chomsky would argue it is inadequate, or more harshly, kind of shallow

Ever since the 1930s, young people in America have reported feeling increasingly anxious and depressed. And no one knows exactly why.One of the researchers who has done the most work on this subject is Dr. Jean Twenge, a social psychologist at San Diego State University who is the author of Generation Me: Why Today’s Young Americans Are More Confident, Assertive, Entitled—and More Miserable Than Ever Before. She’s published a handful of articles on this trajectory, and the underlying story, she thinks, is a rather negative one. “I think the research tells us that modern life is not good for mental health,” she said.

The words “depression” and “anxiety” themselves, after all, mean very different things to someone asked about them in 1935 as compared to 1995, so surveys that invoke these concepts directly only have limited utility for longitudinal study. To get around this, Twenge prefers to rely on surveys and inventories in which respondents are asked about specific symptoms which are frequently correlated with anxiety and depression

Much of the richest data on this question, then, comes from the Minnesota Multiphasic Personality Inventory (MMPI), which has been administered to high school and college students since the 1930s — and which includes many questions about symptoms. Specifically, it asks — among many other things — whether respondents feel well-rested when they wake up, whether they have trouble thinking, and whether they have experienced dizzy spells, headaches, shortness of breath, a racing heart, and so on.