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knudsenlu

The Theory That Explains the Structure of the Internet - The Atlantic - 1 views

  • A paper posted online last month has reignited a debate about one of the oldest, most startling claims in the modern era of network science: the proposition that most complex networks in the real world—from the World Wide Web to interacting proteins in a cell—are “scale-free.” Roughly speaking, that means that a few of their nodes should have many more connections than others, following a mathematical formula called a power law, so that there’s no one scale that characterizes the network.
  • Purely random networks do not obey power laws, so when the early proponents of the scale-free paradigm started seeing power laws in real-world networks in the late 1990s, they viewed them as evidence of a universal organizing principle underlying the formation of these diverse networks. The architecture of scale-freeness, researchers argued, could provide insight into fundamental questions such as how likely a virus is to cause an epidemic, or how easily hackers can disable a network.
  • Amazingly simple and far-reaching natural laws govern the structure and evolution of all the complex networks that surround us,” wrote Barabási (who is now at Northeastern University in Boston) in Linked. He later added: “Uncovering and explaining these laws has been a fascinating roller-coaster ride during which we have learned more about our complex, interconnected world than was known in the last hundred years.”
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  • “These results undermine the universality of scale-free networks and reveal that real-world networks exhibit a rich structural diversity that will likely require new ideas and mechanisms to explain,” wrote the study’s authors, Anna Broido and Aaron Clauset of the University of Colorado at Boulder.
  • Network scientists agree, by and large, that the paper’s analysis is statistically sound. But when it comes to interpreting its findings, the paper seems to be functioning like a Rorschach test, in which both proponents and critics of the scale-free paradigm see what they already believed to be true. Much of the discussion has played out in vigorous Twitter debates.
  • The scale-free paradigm in networks emerged at a historical moment when power laws had taken on an outsize role in statistical physics. In the 1960s and 1970s, they had played a key part in universal laws that underlie phase transitions in a wide range of physical systems, a finding that earned Kenneth Wilson the 1982 Nobel Prize in physics. Soon after, power laws formed the core of two other paradigms that swept across the statistical-physics world: fractals, and a theory about organization in nature called self-organized criticality.
  • From the beginning, though, the scale-free paradigm also attracted pushback. Critics pointed out that preferential attachment is far from the only mechanism that can give rise to power laws, and that networks with the same power law can have very different topologies. Some network scientists and domain experts cast doubt on the scale-freeness of specific networks such as power grids, metabolic networks, and the physical internet.
  • If you were to observe 1,000 falling objects instead of just a rock and a feather, Clauset says, a clear picture would emerge of how both gravity and air resistance work. But his and Broido’s analysis of nearly 1,000 networks has yielded no similar clarity. “It is reasonable to believe a fundamental phenomenon would require less customized detective work” than Barabási is calling for, Clauset wrote on Twitter.
knudsenlu

How Psychologists Predict We'll React to Alien News - The Atlantic - 0 views

  • On the night before Halloween in 1938, a strange story crackled over radios across the United States. An announcer interrupted the evening’s regular programming for a “special bulletin,” which went on to describe an alien invasion in a field in New Jersey, complete with panicked eyewitness accounts and sounds of gunfire. The story was, of course, fake, a dramatization of The War of The Worlds, the science-fiction novel published by H. G. Wells in 1898. But not all listeners knew that. The intro to the segment was quite vague, and those who tuned in a few minutes into the show found no suggestion that what they were hearing wasn’t true.
  • The exact nature of the reaction of these unlucky listeners has been debated in the decades since the broadcast. Some say thousands of people dashed out of their homes and into the streets in terror, convinced the country was under attack by Martians. Others say there was no such mass panic. Regardless of the actual scale of the reaction, the event helped cement an understanding that would later be perpetuated in science-fiction television shows and films: Humans, if and when they encounter aliens, probably aren’t going to react well.
  • But what if the extraterrestrial life we confronted wasn’t nightmarish and intelligent, as it’s commonly depicted, but rather microscopic and clueless?
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  • Microscopic organisms don’t make for good alien villains, but our chances of discovering extraterrestrial microbial life seem better than encountering advanced alien civilizations, Varnum says. In recent years, more and more scientists have begun to suspect that microbes may exist on moons in our solar system, in the subsurface oceans of Europa and Enceladus and the methane lakes of Titan.
  • In every case, the text-analysis software showed that people, journalists and non-journalists alike, seemed to exhibit more positive than negative emotions in response to news of extraterrestrial microbes.
  • In general, media mentions and their predictive abilities are imperfect measures. Text-analysis software itself has some gaps; the program can’t, for example, detect sarcasm.
  • “A lot of worldviews, both religious and secular, have shown themselves to be pretty flexible,” Varnum says. “The Catholic Church eventually made peace with a heliocentric solar system, right?”
runlai_jiang

The Big Tech Trends to Follow at CES 2018 - The New York Times - 0 views

  • magine this: When you leave the house, your air conditioner and lights turn off automatically. Then when a motion sensor detects a person in the house, like your house cleaner, it sends an alert to your phone. When you arrive home, a camera recognizes who you are and the door automatically unlocks.
  • Automated technologies like these will be at the forefront of CES, one of the world’s largest tech conventions, next week in Las Vegas. They underline one major trend: Increasingly, the innovations that are making their way into your personal technology aren’t physical electronics or gadgets at all.
  • he culmination of software, algorithms and sensors working together to make your everyday appliances smarter and more automated. It is
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  • Alexa and Her CounterpartsAlexa, Amazon’s intelligent assistant that listens to your voice commands to play music, order diapers and place a phone call, will be everywhere at CES.
  • Smart CitiesNowadays, it’s easy to shop for high-quality internet-connected home accessories, like light bulbs, thermostats and security cameras. At CES, Samsung is even planning to introduce a smart refrigerator at the electronics show that can listen to voice commands to control other home accessories.
  • Smarter CarsSelf-driving-car enthusiasts like Elon Musk, the chief executive of Tesla, dream of a future where driverless cars eliminate traffic accidents while letting people do work on their commutes.They can keep dreaming: Autonomous vehicles still have a long way to go before they become safe and properly regulated.
  • Next-Generation Wireless TechnologyAs a growing number of devices rely on artificial intelligence, they will require faster bandwidth speeds. At CES, wireless companies like AT&T and Verizon are expected to give progress reports on so-called 5G, the fifth-generation network technology.With 5G, wireless carriers envision an era of incredibly fast speeds that let smartphone users download a movie in less than five seconds — roughly 100 times faster than the current network technology, 4G. Even more important, 5G is expected to greatly reduce latency to let devices communicate with each other with extremely fast response times.
sanderk

A coronavirus vaccine should be affordable by everyone - STAT - 0 views

  • As the coronavirus that causes COVID-19 spreads in more than 60 countries, the race to develop a vaccine to prevent the illness has taken on new urgency. In a meeting with CEOs of major drug companies this week, President Trump ramped up the pressure, suggesting that vaccines could come to market faster than the 12- to 18-month timeline most researchers think is realistic.
  • But while the Trump administration is pushing drug companies to meet faster timelines, it hasn’t addressed an equally urgent question: What will be done to ensure the vaccine is accessible for those who need it most?
  • Making vaccines available only to the rich is not just immoral, it’s also bad public health policy. We’ll want everyone, rich or poor, insured or not, to be protected from the new coronavirus. Protecting others helps to protect everyone.
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  • The final price of any vaccine should be one that governments of poor and rich countries alike can afford so all citizens can get it free at the point of care.
  • Without price controls, poor countries are unlikely to be able to afford or access enough vaccines to protect their populations.
  • A sad truth we have learned from past global pandemics is that poor people are hit first and worst. Vaccines are most urgently needed where health systems are fragile, and where the effects of this new coronavirus could be catastrophic.
  • Many countries lack the resources, infrastructure, and health care personnel to mount full-scale efforts to detect the virus and prevent it from spreading, meaning it will move quickly and easily among populations. In these settings, the number of cases is likely to grow exponentially, putting stress on already burdened health care workers and facilities and making it harder to provide timely care for those who are ill. Vaccines will be an important tool for preventing such a catastrophe.
  • For those with resources — rich countries and rich people — a vaccine would be valuable, one of several tools we will need to prevent the most serious effects of the new coronavirus. But for those who are poor or who live in poor countries, it may be essential. Without it, they will suffer disproportionately and unnecessarily.
  • To let a coronavirus vaccine be monopolized by the rich will perpetuate the unjust economics of outbreaks, where the poor always pay the heaviest price. Allowing this to happen would be a moral disgrace.
katherineharron

Mysterious fast radio bursts helped detect missing matter in the universe, study says -... - 0 views

  • Mysterious fast radio bursts have been used to unlock another strange aspect of the universe: the case of the "missing matter."
  • Astronomers have yet to determine what causes these fast radio bursts, which are unpredictable but can be spotted and traced back to their origin using sensitive telescopes.
  • Normal matter, called baryonic matter in this study, is made of the protons and neutrons that comprise both humans and star stuff. But astronomers could only account for about half of it that should exist in the universe.
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  • Unaccounted for, this missing matter was predicted to exist, but hard to find. In fact, astronomers have been searching for it over the last 30 years, the researchers said. Measurements of the Big Bang show how much matter was present in the early days of the universe, suggesting its existence.
  • "It turned out that it was hiding in a density so low that it does not emit light, it doesn't absorb it, and it doesn't reflect it," he said.
  • "The radiation from fast radio bursts gets spread out by the missing matter in the same way that you see the colors of sunlight being separated in a prism," Macquart said.
  • "Their millisecond durations made it very easy to measure the effect of dispersion — the process by which their longer wavelength emission is delayed with respect to their shorter wavelength emission is delayed — and hence to measure exactly how much matter they have encountered on their multi-billion year intergalactic journeys to Earth," Macquart said.
  • Astronomers were able to pin down the source of a repeating fast radio burst in 2017. But single radio bursts are harder to pinpoint because they don't reoccur.
  • "ASKAP both has a wide field of view, about 60 times the size of the full Moon, and can image in high resolution," said Ryan Shannon, study coauthor and associate professor at Swinburne University of Technology, in a statement. "This means that we can catch the bursts with relative ease and then pinpoint locations to their host galaxies with incredible precision.
  • "We've discovered the equivalent of the Hubble-Lemaître Law for galaxies, only for fast radio bursts," Macquart said. "The Hubble-Lemaître Law, which says the more distant a galaxy from us, the faster it is moving away from us, underpins all measurements of galaxies at cosmological distances."
tongoscar

Coronavirus Cases Seemed to Be Leveling Off. Not Anymore. - The New York Times - 0 views

  • On Thursday, health officials in China reported more than 14,000 new cases in Hubei Province alone. A change in diagnostic criteria may be the reason.
  • The news seemed to be positive: The number of new coronavirus cases reported in China over the past week suggested that the outbreak might be slowing — that containment efforts were working.
  • The sharp rise in reported cases illustrates how hard it has been for scientists to grasp the extent and severity of the coronavirus outbreak in China, particularly inside the epicenter, where thousands of sick people remain untested for the illness.
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  • Hospitals in Wuhan, China — the largest city in Hubei Province and the center of the epidemic — have struggled to diagnose infections with scarce and complicated tests that detect the virus’s genetic signature directly. Other countries, too, have had such issues.
  • In China, health officials have been under exceptional strain. Hospitals are overwhelmed, and huge new shelters are being erected to warehouse patients. Medical resources are in short supply. It’s never been clear who is being tested.
  • The push to prioritize lung scans seems to have begun with a social media campaign by a physician in Wuhan, who last week called for using the scans to simplify the screening of patients and to accelerate their hospitalization and treatment.
  • The new coronavirus is highly transmissible and will be difficult to squelch. A single infected “super-spreader” can infect dozens of others. Outbreaks can seem to recede, only to rebound in short order, as the weather or conditions change.
  • In Hong Kong, people living 10 floors apart were infected, and an unsealed pipe was blamed. A British citizen apparently infected 10 people, including some at a ski chalet, before he even knew he was sick.
  • Unlike MERS and SARS, both diseases caused by coronaviruses, the virus spreading from China appears to be highly contagious, though it is probably less often fatal.
  • The country is so central to the world economy that it can easily “seed” epidemics everywhere, he said.
tongoscar

What We Know Today about Coronavirus SARS-CoV-2 and Where Do We Go from Here - 0 views

  • The severe acute respiratory syndrome coronavirus SARS-CoV-2 (2019-nCoV) outbreak is an important reminder that the global community must strengthen national and international programs for early detection and response to future disease outbreaks.
  • Sequencing novel viruses helps remove the fear of the unknown by defining the viral genomic sequence for dissection and interpretation. While we are within the first two months of the first report to the World Health Organization (WHO) of SARS-CoV-21, and there remains much to learn, modern technology has identified and characterized the virus, sequenced its full genome, and started to describe the genetic evolution of the virus over a short time period.
  • On January 24, the first SARS-CoV-2 genome was published in the New England Journal of Medicine.2 To our knowledge, this is the first time a complete genome of a novel infectious agent has been publicly available in such a short time after the first case was reported to the WHO.
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  • As of February 7, over 80 SARS-CoV-2 genomes have been shared through the Global Initiative to Share All Influenza Data (GISAID) and GenBank, which will catalyze the research to understanding of the origin of the new virus, the epidemiology and transmission routes, and facilitate development of diagnostic and treatment strategies.3 Understanding the genome of SARS-CoV-2 early, provided unprecedented insight into dynamics of viral spread and impacted response strategies.
  • Within less than 60 days of reporting, global scientists know the likely origin of the virus, how similar it is to related viruses that are better understood, and what therapies may be applicable.
  • Analysis of the genomic information currently available, indicates SARS-CoV-2 is most closely related to a known bat SARS-like Coronavirus, indicating bats as the likely origin.
  • While this is early in the outbreak, there are no specific drugs available to treat SARS-CoV-2. There is high sequence conservation between SARS-CoV-2 and related SARS-CoV in viral drug targets, such as in protease and polymerase enzymes.
  • Reports from Africa indicate no positive cases of SARS-CoV-2 thus far. However, the lack of confirmed diagnoses may be due to a limited capacity for in-country testing rather than the true epidemiology of the virus.
sanderk

A High-Tech System to Make Homes More Healthy - The New York Times - 0 views

  • Darwin is operated through a Wi-Fi-enabled tablet that resembles an iPad and displays metrics on conditions across the home. Properties with the system are constructed with air quality sensors and filters that detect and remove impurities like pollution and smoke. They also have water purifiers that get rid of chlorine, heavy metals and other particles from tap water.
  • “We’re indoors for most of our lives, and while we may not be able to change that, Darwin gives you the ability to change your environment,” he said.
  • Not many are equipped with such high-tech systems as Darwin, but these communities offer wellness in other ways: growing produce for residents, for example, or providing outdoor space and fitness classes.
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  • With their high ceilings, tall windows, herringbone floors and granite stone bathrooms, these homes, like the Simonds properties, feel contemporary; the residences on the ground floors have 645-square-foot outdoor courtyards.
katherineharron

A cold Neptune and two super-Earths are among newly found exoplanets around nearby star... - 0 views

  • Five exoplanets and eight planet candidates have been found around nearby stars, including a "cold Neptune" and two super-Earths that are potentially habitable, according to a new study. The two super-Earths, GJ180d and GJ229Ac, were found around small red dwarf stars that are 19 and 40 light-years away from our sun, while the cold Neptune was found around a similar star that's 29.5 light-years away.
  • Meanwhile, the other super-Earth, GJ229Ac, is the nearest temperate super-Earth in a system where the host star is also orbited by a brown dwarf. Brown dwarfs are known as failed stars that can't sustain the hydrogen fusion needed to power them
  • "GJ 433 d is the nearest, widest and coldest Neptune-like planet ever detected," said Fabo Feng, lead study author and astronomer at the Carnegie Institution for Science. A multitude of exoplanets, especially terrestrial planets like Earth, have been found around red dwarf stars. They're smaller and cooler than our sun, and they're the most common star in our galaxy. Exoplanets tend to orbit closer to these stars and still be within the star's habitable zone, or the perfect distance for the planet to be temperate and potentially host liquid water on their surfaces.
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  • "We eventually want to build a map of all of the planets orbiting the nearest stars to our own solar system, especially those that are potentially habitable," said Jeffrey Crane, study co-author and astronomer at the Carnegie Institution for Science.
manhefnawi

Opinion | Does Math Make You Smarter? - The New York Times - 0 views

  • Various studies point to the conclusion that subjecting the mind to formal discipline — as when studying geometry or Latin — does not, in general, engender a broad transfer of learning. There is no sweeping increase of a general capacity for tasks like writing a speech or balancing a checkbook.
  • Many reasons have been advanced for this poor showing, including the lack of relevance of such an abstract exercise to people’s daily lives.
  • Most people reflexively eliminate the cards not explicitly specified in the rule (the F and the 2) and then continue with slower, more analytic processing only for the E and the 5. In this, they rely on an initial snap judgment about superficial similarity, a tendency that some scholars speculate evolved in humans because in most real-world contexts, quickly detecting such similarities is a good strategy for survival.
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  • I propose we start to teach the Wason selection task in mathematics courses at the high-school level and higher. The puzzle captures so much that is essential to mathematics: the nuts and bolts of inference, the difficulty of absorbing abstract concepts when removed from the context of real-world experience, the importance of a slow, deliberative cogitative process and the pitfalls of instant intuitive judgments.
tongoscar

In Hong Kong, the coronavirus outbreak is deepening the political divide from the 2019 ... - 0 views

shared by tongoscar on 19 Feb 20 - No Cached
  • Rumors had spread that toilet paper supply would be cut off due to new border closures with mainland China, implemented in an effort to contain the novel coronavirus outbreak.
  • The government's reassurances and calls for order went unheeded as millions of residents, gripped by fear and suspicion, descended on stores citywide to panic buy.The novel coronavirus, which originated in Wuhan, China, was first detected in Hong Kong on January 22. Since then, there have been 62 confirmed cases and two deaths in the city.
  • The numbers are far lower than in mainland China, where at least 1,868 people have died so far -- but Hong Kong carries the memories of the deadly Severe Acute Respiratory Syndrome (SARS) outbreak in 2003, and people aren't taking any chances.
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  • By the time she withdrew the bill -- that would have allowed criminal suspects to be extradited across the border to mainland China -- protesters' demands had expanded to include action on deeper social grievances.
  • In January, many Hong Kongers across various sectors, including elected lawmakers, called to shut Hong Kong's borders with mainland China to contain the virus. But these demands also reintroduced familiar strands of localism, an ideology focused on preserving Hong Kong's autonomy.
  • This is why closing the Chinese borders is a politically significant and symbolic act -- and perhaps why Lam resisted doing so for weeks.
  • The 2019 protest movement may appear to have fizzled out -- but it educated an entire city and generation of youth on organized resistance. Now, this spirit of political action has been redirected toward the outbreak, as people protest for a stronger government response.More than 7,000 health care workers participated in a week-long union strike in early February to demand closed borders; that's nearly 10% of all medical staff of Hong Kong's Hospital Authority.The labor union that organized the strike was one of several born from the 2019 unrest, founded during the tail end of the protests.
  • Hong Kong's schools are shut until at least mid-March, and many businesses have closed or have instructed employees to work from home.With cases of community transmission confirmed, many people are staying at home for weeks at a time to avoid infection, only venturing out for groceries or quick strolls.
  • Fear and anger are palpable in the city, especially earlier this week with the disappearance of two people who violated quarantine after returning from mainland China. They were found after being added to a police wanted list.
Javier E

No, a Negative Coronavirus Test Does Not Mean You Can Safely Socialize - The New York T... - 0 views

  • he main reason is that a test gives information about the level of the virus at one point in time. A person could be infected but not have enough virus yet for it to register on a test. Or, a person may become infected in the hours or days after taking a test. Also, the tests do not have 100 percent accuracy.
  • A test “filters out those who are positive and definitely shouldn’t be there,” she said. “Testing negative basically changes nothing about behavior. It still means wear a mask, distance, avoid indoors if you can.”
  • Taking multiple tests over a period of days gives a clearer answer. But experts cautioned that no test — regardless of how many times it’s taken in succession — can definitively determine whether someone infected by the coronavirus is contagious, or no longer poses a transmission risk to other people.
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  • a full 64 percent said that even if they tested negative, they would not be comfortable spending time indoors with people they don’t live with.
  • In an informal survey of 670 epidemiologists, just 6 percent said that if they recently tested negative for the virus, they would be comfortable spending time indoors with others without precautions
  • “The risk that you have, if everyone is tested before you get together to sit down for dinner, dramatically decreases. It might not ever be zero but, you know, we don’t live in a completely risk-free society.”
  • Before gathering with others, Dr. Mina said, people could combine a negative test with a two-week quarantine if they’re able
  • Avoiding any contact with other people for a week or more before taking a test is a powerful tool, said Jeffrey Townsend, a professor of biostatistics at the Yale School of Public Health. Not only does it decrease exposure, but it also gives the virus more opportunity to reach detectable levels in infected people, his research has found.
manhefnawi

This Software Can Guess What People Are Looking At | Mental Floss - 0 views

  • When it comes to the human brain, scientists still have a lot left to learn. One function that remains mysterious? How we're able to interpret two-dimensional pictures—like a picture of a cat on a computer screen—into objects we recognize from real life. In order to learn more about this process, researchers from the University of Washington have found a way to use brain implants and advanced software to decode brain signals at nearly the speed of thought.
  • The electrodes in their brains were hooked up to a software that had been programmed to detect two specific brain signal properties: "event-related potentials" that occur in immediate response to an image and "broadband spectral changes" that linger after an image has already been seen. By digitizing brain signals at a rate of 1000 times per second, the software was able to pinpoint which combination of electrode locations and signals best matched the image the patients saw in front of them.
Javier E

A New Alternative to Dark Matter - The Atlantic - 0 views

  • The challenges for alternative gravity theories—collectively known as modified Newtonian dynamics, or MOND—were spelled out in a separate preprint coincidentally published the day after the new model appeared. Chief among them is recasting the leading role dark matter plays in drawing the universe together, as described by a well-established cosmological model known as LCDM, or Lambda cold dark matter.
  • Simply put, LCDM says that we wouldn’t be here without dark matter. The infant universe was so smooth that the gravitational attraction of ordinary matter alone wouldn’t have been enough to gather particles into galaxies, stars, and planets. Enter dark-matter particles. Under the LCDM model, their collective bulk sculpts normal matter into the modern cosmic structures studied by astronomers.
  • LCDM became the standard model of cosmology in part because it so precisely agrees with the CMB. This map of the early universe shows almost imperceptibly thick and thin spots rippling through the cosmos. More recently, researchers have been able to measure the orientation or polarization of the CMB’s light more precisely. Any successful cosmology will need to establish a comprehensive history of the cosmos by reproducing these three observations: the CMB’s temperature, the CMB’s polarization, and the current distribution of galaxies and galaxy clusters.
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  • Recreating these and other features without LCDM’s titular ingredient, Spergel showed, requires the finest of theoretical needle threading. “We haven’t disproven the existence of all these [modified-gravity theories],” he says. “But any alternative theory has to jump through these hoops.”
  • Złosnik and Skordis believe they’ve done just that—although in a way that might surprise MOND skeptics and fans alike. They managed to construct a theory of gravity that contains an ingredient that acts exactly like an invisible form of matter on cosmic scales, blurring the line between the dark matter and MOND paradigms.
  • Their theory, dubbed RelMOND, adds to the equations of general relativity an omnipresent field that behaves differently in different arenas. On the grandest scales, where the universe noticeably stretches as it expands, the field acts like invisible matter. In this mode, which Złosnik calls “dark dust,” the field could have shaped the visible universe just as dark matter would
  • RelMOND “cannot do worse than LCDM,” says Złosnik, who notes that it very closely mimics that theory for the universe as a whole.
  • But if we zoom in on a galaxy, where the fabric of space holds rather still, the field acts in a way that’s true to its MOND roots: It entwines itself with the standard gravitational field, beefing it up just enough to hold a galaxy together without extra matter
  • (The researchers aren’t yet sure how the field acts for larger clusters of galaxies, a perennial MOND sore spot. They suggest that this intermediate scale might be a good place to look for observational clues that could set the theory apart.)
  • Despite this mathematical achievement by Złosnik and Skordis, dark matter remains the simpler theory. Constructing the new field takes four new moving mathematical parts, while LCDM handles dark matter with just one. Hooper likens the situation to a detective debating whether a person at a murder scene is the murderer or has been framed by the CIA. Even if the available evidence matches both theories, one requires less of a leap.
Javier E

New cancer treatment destroys tumours in terminally ill, finds trial | Cancer | The Gua... - 0 views

  • In a landmark trial, a cocktail of immunotherapy medications harnessed patients’ immune systems to kill their own cancer cells and prompted “a positive trend in survival”, according to researchers at the Institute of Cancer Research (ICR), London, and the Royal Marsden NHS foundation trust.
  • Scientists found the combination of nivolumab and ipilimumab medications led to a reduction in the size of tumours in terminally-ill head and neck patients. In some, their cancer vanished altogether, with doctors stunned to find no detectable sign of disease.
  • the immunotherapy treatment also triggered far fewer side-effects compared with the often gruelling nature of “extreme” chemotherapy,
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  • The results from the phase 3 trial, involving almost 1,000 dying head and neck cancer patients, were early and not statistically significant but were still “clinically meaningful”, the ICR said, with some patients living months or years longer and suffering fewer side effects.
  • When the research nurses called to tell me that, after two months, the tumour in my throat had completely disappeared, it was an amazing moment,” said Ambrose. “While there was still disease in my lungs at that point, the effect was staggering.”
Javier E

The Real Reason You and Your Neighbor Make Different Covid-19 Risk Decisions - WSJ - 0 views

  • Personality traits that are shaped by genetics and early life experiences strongly influence our Covid-19-related decisions, studies from the U.S. and Japan have found.
  • In a study of more than 400 U.S. adults, Dr. Byrne and her colleagues found that how people perceive risks, whether they make risky decisions, and their preference for immediate or delayed rewards were the largest predictors of whether they followed public-health guidelines when it came to wearing masks and social distancing.
  • These factors accounted for 55% of the difference in people’s behaviors—more than people’s political affiliation, level of education or age.
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  • Dr. Byrne and her colleagues measured risky decision-making by presenting people with a gambling scenario. They could choose between two bets: One offered a guaranteed amount of money, while the other offered the possibility of a larger amount of money but also the possibility of receiving no cash. A different exercise measured people’s preference for immediate versus delayed rewards: Participants could choose a certain amount of money now, or a larger amount later.
  • Study subjects also reported Covid-19 precautions they had taken in their daily lives, including masking and social distancing.
  • with Covid-19, people don’t feel sick immediately after an exposure so the benefits of wearing a mask, social distancing or getting vaccinated aren’t immediately apparent. “You don’t see the lives you potentially save,” she says
  • “People generally are more motivated by immediate gratification or immediate benefits rather than long-term benefits, even when the long-term benefits are much greater,
  • Research has also found being extroverted or introverted affects how people make decisions about Covid-19 precautions. A recent study of more than 8,500 people in Japan published in the journal PLOS One in October 2020 found that those who scored high on a scale of extraversion were 7% less likely to wear masks in public and avoid large gatherings, among other precautions.
  • The study also found that people who scored high on a measure of conscientiousness—valuing hard work and achievement—were 31% more likely to follow Covid-19 public-health precautions.
  • Scientists believe that a person’s propensity to take risks is partly genetic and partly the result of early life experiences
  • Certain negative childhood experiences including physical, emotional or sexual abuse, parental divorce, or living with someone who was depressed or abused drugs or alcohol are linked to risky behavior in adulthood like smoking and drinking heavily, other research has found.
  • Studies of twins have generally found that about 30% of the difference in individual risk tolerance is genetic
  • And scientists have discovered that the brains of people who are more willing to take risks look different than those of people who are more cautious.
  • ambling task had differences in the structure and function of the amygdala, a part of the brain involved in detecting threats, and the prefrontal cortex, a region involved in executive
  • Even people who have the same information and a similar perception of the risks may make different decisions because of the ways they interpret the information. When public-health officials talk about breakthrough infections in vaccinated individuals being rare, for example, “rare means different things” to different people
Javier E

How to Accept the Things You Can't Change - The Atlantic - 0 views

  • Everyone—even the most privileged among us—has circumstances they would like to change in their life.
  • How might you improve the situation? Your answer might be, “I should move, get a new job, and meet new people.” In other words, you should change the outside world to make it better for you.
  • Between the conditions around you and your response to them is a space. In this space, you have freedom. You can choose to try remodeling the world, or you can start by changing your reaction to it.
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  • Sometimes, changing your circumstances is difficult but absolutely necessary, such as in cases of abuse or violence. And sometimes, changing your circumstances is fairly easy: If you are lethargic every morning, start going to bed earlier.
  • But in the gray areas in between, fighting against reality can be impossible, or incredibly inefficient. Maybe you have been diagnosed with a chronic illness for which there are no promising treatment options. Perhaps your romantic partner has left you against your wishes and cannot be persuaded otherwise.
  • In these sorts of situations, changing how you feel can actually be much easier than changing your physical reality, even if it seems unnatural.
  • No surprise, then, that chronic stress often leads to maladaptive coping mechanisms in modern life. These include the misuse of drugs and alcohol, rumination on the sources of stress, self-harm, and self-blaming
  • That can be blamed in part on biology. Negative emotions such as anger and fear activate the amygdala, which increases vigilance toward threats and improves your ability to detect and avoid danger.
  • In other words, stress makes you fight, flee, or freeze—not think, What would a prudent reaction be at this moment? Let’s consider the options.
  • But in the modern world, stress and anxiety are usually chronic, not episodic.
  • you no longer need your amygdala to help you outrun the tiger without asking your conscious brain’s permission. Instead, you use it to handle the nonlethal problems that pester you all day long. Even if you don’t have tigers to outrun, you can’t relax in your cave, because the emails are piling up.
  • Your emotions can seem out of your control at the best of times, and even more so during a crisis
  • Similarly, the Stoics believed that human reason, practiced studiously, could override knee-jerk emotions.
  • Buddhism posits that our minds are habitually unbalanced, but not intrinsically so; the key is to build new habits of thinking.
  • These ideas (especially the last) have inspired modern schools of psychotherapy, such as rational emotive behavior therapy and cognitive behavioral therapy, which aim to create practical strategies for changing our reactions to negative situations in our life—and thus becoming happier.
  • 4. Give more.
  • you can follow four steps to arrive at a happier frame of mind:
  • 1. Notice your feelings.
  • Self-observation requires that you be mindful of what you are feeling in the moment and approach your emotions with detached curiosity.
  • Say you are sick of working from home all day, with endless Zoom meetings and no real human contact. Rather than fantasizing about quitting, spend some time dissecting your boredom and discomfort. At what time of day are they worst?
  • Following this procedure during the coronavirus pandemic shutdowns, I started taking virtual meetings while out for a walk. It made a big difference.
  • 2. Accept your feelings.
  • in much of life, negative feelings are part of a full human experience; erasing them would make life grayer. Furthermore, ample research shows that negative emotions and experiences help us find life’s meaning and purpose.
  • In the journal you started in Step 1 above, ponder the things that you can’t realistically alter and the emotions they spark in you. Ask what you are learning about yourself from each of these feelings, and how you might grow as a result.
  • 3. Lower your expectations.
  • Once, as a young man, I told my father over the phone that I planned to quit my job. “Why?” he asked. “Because it doesn’t make me happy,” I told him. He paused for a long time, and finally said, “What makes you so special?
  • My problem—and it’s a common one—was that I had set unreasonable expectations about how happy the world was supposed to make me.
  • Calmly ask yourself whether you’re asking the world for something it can’t or won’t give you. If you are, you might be looking in the wrong place for your bliss
  • you shouldn’t assume that all your happiness can come from any single romance, material object, or activity. You need a “portfolio” approach, balancing faith or philosophy, family, friendship, and work in which you earn your success and serve others.
  • Ancient thinkers recognized this difficulty but believed that we can manage our reactions effectively if we have the right tools.
  • Research from the INSEAD business school in France shows that people who consider themselves a victim of circumstances don’t feel like they have any responsibility for them. They are also likely to be victimizers themselves, hurting the people who try to help them.
  • One way to break this cycle is to help others voluntarily and charitably. Not only is serving others one of the most effective ways to raise one’s own happiness; maintaining the two opposing ideas that you are both a victim and a helper is very difficult.
Javier E

Climate Change Data Deluge Has Scientists Scrambling for Solutions - WSJ - 0 views

  • For decades, scientists working to predict changes in the climate relied mostly on calculations involving simple laws of physics and chemistry but little data from the real world. But with temperatures world-wide continuing to rise—and with data-collection techniques and technologies continuing to advance—scientists now rely on meticulous measurements of temperatures, ocean currents, soil moisture, air quality, cloud cover and hundreds of other phenomena on Earth and in its atmosphere.
  • “Now we can truly do climate studies because now we have observations to precisely say how weather trends have changed and are changing,
  • “When you are trying to develop long-term environmental records, including climate records, consistent measurement is incredibly valuable,” says Kevin Murphy, who as NASA’s chief science data officer oversees an archive of Earth observation data used by 3.9 million people last year. “It’s irreplaceable data.”
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  • Over the next decade, officials managing the main U.S. repositories of climate-related information expect their archives’ total volume to grow from about 83 petabytes today to more than 650 petabytes.
  • One petabyte of digital memory can hold thousands of feature-length movies, with 650 enough to hold the contents of the Library of Congress 30 times over.
  • All that information, though, is more than conventional data storage can handle and more than any human mind can readily assimilate,
  • To accommodate it all, the federal workers tasked with managing the data are moving it into the cloud, which offers almost unlimited memory storage while eliminating the need for scientists to maintain their own on-site archive
  • archive managers are devising new analytical techniques and adapting a standard format for the data no matter who collected it and who wants to study it.
  • In essence, they are reinventing climate science from the ground up.
  • “We are in the midst of a technology evolution,
  • As of last September, government agencies and private companies had about 900 Earth-orbiting satellites gathering data about our planet, according to the Union of Concerned Scientists. That is almost three times as many as were aloft in 2008. More are being readied for launch.
  • ASA’s $1 billion Surface Water and Ocean Topography mission will measure Earth’s lakes, rivers and oceans in the first detailed global survey of the planet’s surface water.
  • That is a drop in the data bucket compared with the space agency’s $1.5 billion Nisar radar imaging satellite, which is scheduled for launch in January 2023. Its sensors will detect movements of the planet’s land, ice sheets and sea ice as small as 0.4 inches, transmitting 80 terabytes of data every day.
  • With current data handling systems and typical internet connections, it would take a climate researcher about a year to download just four days’ worth of Nisar dat
  • NASA and NOAA are working with Amazon Web Services, Google Cloud and Microsoft Corp. to move their climate databases into the cloud.
  • Earlier this year, the United Nations Intergovernmental Panel on Climate Change for the first time used data on past climate behavior to gauge the reliability of climate models for policy makers.
criscimagnael

Explained: Social media and the Texas shooter's messages | Explained News,The Indian Ex... - 0 views

  • Could technology companies have monitored ominous messages made by a gunman who Texas authorities say massacred 19 children and two teachers at an elementary school? Could they have warned the authorities? Answers to these questions remain unclear
  • But if nothing else, the shooting in Uvalde, Texas, seems highly likely to focus additional attention on how social platforms monitor what users are saying to and showing each other.
  • Shortly thereafter, Facebook stepped in to note that the gunman sent one-to-one direct messages, not public posts, and that they weren’t discovered until “after the terrible tragedy”.
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  • Some reports appear to show that at least some of the gunman’s communications used Apple’s encrypted iPhone messaging services, which makes messages almost impossible for anyone else to read when sent to another iPhone user.
  • Facebook parent company Meta, which also owns Instagram, says it is working with law enforcement but declined to provide details.
  • A series of posts appeared on his Instagram in the days leading up to the shooting, including photos of a gun magazine in hand and two AR-style semi-automatic rifles. An Instagram user who was tagged in one post shared parts of what appears to be a chilling exchange on Instagram with Ramos, asking her to share his gun pictures with her more than 10,000 followers.
  • Meta has said it monitors people’s private messages for some kinds of harmful content, such as links to malware or images of child sexual exploitation. But copied images can be detected using unique identifiers — a kind of digital signature — which makes them relatively easy for computer systems to flag. Trying to interpret a string of threatening words — which can resemble a joke, satire or song lyrics — is a far more difficult task for artificial intelligence systems.
  • Facebook could, for instance, flag certain phrases such as “going to kill” or “going to shoot”, but without context — something AI in general has a lot of trouble with — there would be too many false positives for the company to analyze.
  • A recent Meta-commissioned report emphasized the benefits of such privacy but also noted some risks — including users who could abuse the encryption to sexually exploit children, facilitate human trafficking and spread hate speech.
  • Security experts say this could be done if Apple were to engineer a “backdoor” to allow access to messages sent by alleged criminals. Such a secret key would let them decipher encrypted information with a court order.
Javier E

Ian Hacking, Eminent Philosopher of Science and Much Else, Dies at 87 - The New York Times - 0 views

  • In an academic career that included more than two decades as a professor in the philosophy department of the University of Toronto, following appointments at Cambridge and Stanford, Professor Hacking’s intellectual scope seemed to know no bounds. Because of his ability to span multiple academic fields, he was often described as a bridge builder.
  • “Ian Hacking was a one-person interdisciplinary department all by himself,” Cheryl Misak, a philosophy professor at the University of Toronto, said in a phone interview. “Anthropologists, sociologists, historians and psychologists, as well as those working on probability theory and physics, took him to have important insights for their disciplines.”
  • Professor Hacking wrote several landmark works on the philosophy and history of probability, including “The Taming of Chance” (1990), which was named one of the best 100 nonfiction books of the 20th century by the Modern Library.
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  • “I have long been interested in classifications of people, in how they affect the people classified, and how the effects on the people in turn change the classifications,” he wrote in “Making Up People
  • His work in the philosophy of science was groundbreaking: He departed from the preoccupation with questions that had long concerned philosophers. Arguing that science was just as much about intervention as it was about representation, be helped bring experimentation to center stage.
  • Regarding one such question — whether unseen phenomena like quarks and electrons were real or merely the theoretical constructs of physicists — he argued for reality in the case of phenomena that figured in experiments, citing as an example an experiment at Stanford that involved spraying electrons and positrons into a ball of niobium to detect electric charges. “So far as I am concerned,” he wrote, “if you can spray them, they’re real.”
  • His book “The Emergence of Probability” (1975), which is said to have inspired hundreds of books by other scholars, examined how concepts of statistical probability have evolved over time, shaping the way we understand not just arcane fields like quantum physics but also everyday life.
  • “I was trying to understand what happened a few hundred years ago that made it possible for our world to be dominated by probabilities,” he said in a 2012 interview with the journal Public Culture. “We now live in a universe of chance, and everything we do — health, sports, sex, molecules, the climate — takes place within a discourse of probabilities.”
  • Whatever the subject, whatever the audience, one idea that pervades all his work is that “science is a human enterprise,” Ragnar Fjelland and Roger Strand of the University of Bergen in Norway wrote when Professor Hacking won the Holberg Prize. “It is always created in a historical situation, and to understand why present science is as it is, it is not sufficient to know that it is ‘true,’ or confirmed. We have to know the historical context of its emergence.”
  • Hacking often argued that as the human sciences have evolved, they have created categories of people, and that people have subsequently defined themselves as falling into those categories. Thus does human reality become socially constructed.
  • In 2000, he became the first Anglophone to win a permanent position at the Collège de France, where he held the chair in the philosophy and history of scientific concepts until he retired in 2006.
  • “I call this the ‘looping effect,’” he added. “Sometimes, our sciences create kinds of people that in a certain sense did not exist before.”
  • In “Why Race Still Matters,” a 2005 article in the journal Daedalus, he explored how anthropologists developed racial categories by extrapolating from superficial physical characteristics, with lasting effects — including racial oppression. “Classification and judgment are seldom separable,” he wrote. “Racial classification is evaluation.”
  • Similarly, he once wrote, in the field of mental health the word “normal” “uses a power as old as Aristotle to bridge the fact/value distinction, whispering in your ear that what is normal is also right.”
  • In his influential writings about autism, Professor Hacking charted the evolution of the diagnosis and its profound effects on those diagnosed, which in turn broadened the definition to include a greater number of people.
  • Encouraging children with autism to think of themselves that way “can separate the child from ‘normalcy’ in a way that is not appropriate,” he told Public Culture. “By all means encourage the oddities. By no means criticize the oddities.”
  • His emphasis on historical context also illuminated what he called transient mental illnesses, which appear to be so confined 0cto their time 0c 0cthat they can vanish when times change.
  • “hysterical fugue” was a short-lived epidemic of compulsive wandering that emerged in Europe in the 1880s, largely among middle-class men who had become transfixed by stories of exotic locales and the lure of trave
  • His intellectual tendencies were unmistakable from an early age. “When he was 3 or 4 years old, he would sit and read the dictionary,” Jane Hacking said. “His parents were completely baffled.”
  • He wondered aloud, the interviewer noted, if the whole universe was governed by nonlocality — if “everything in the universe is aware of everything else.”“That’s what you should be writing about,” he said. “Not me. I’m a dilettante. My governing word is ‘curiosity.’”
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