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first neurosurgeries took place about 7,000 years ago in South America with the boring of holes into hapless patients’ skulls, a process known as trephination. Practitioners of the day believed the source of neurologic and psychiatric disease to be evil spirits inhabiting the brain, and the way to treat such disorders, they reasoned, was to make holes in the skull and let the evil spirits escape. The procedure was surprisingly common, with as many as 1 percent of skulls at some archaeological sites having these holes.

disorders is a consequence of pathological activity within a specific brain circuit. In Parkinson’s disease and dystonia, neurons in the motor circuits misfire, causing aberrant movements of the limbs and torso. Malfunction in circuits that regulate mood can lead to depression.

observing patients’ behavioral changes following the stimulation or inhibition of specific neural circuits, DBS is helping to explain what goes wrong in the brain to cause symptoms

“We’ve reached a point where patients are increasingly facing five- and six-figure price tags for medications that they will take over the course of their lifetimes,” said Matthew Eyles, an executive vice president for America’s Health Insurance Plans, the national trade association for the insurance industry. “If this is the new normal to treat common and chronic conditions, how can any health system sustain that cost?”

Doctors with patients who maintain they are intolerant to statins say they are confronted with a clash between the art and the science of medicine.

Dr. Peter Libby, a doctor and researcher at Brigham and Women’s Hospital in Boston, said that in his role as a physician, “the patient is always right.” But, he added, “as a scientist, I find randomized, large-scale, double-blind studies more persuasive than anecdote.”

They are, however, great allies and enablers of narcissism. Alongside their built-in eagerness to be liked is a built-in eagerness to reflect well on us. Our lives look a lot more interesting when they’re filtered through the sexy Facebook interface.

To friend a person is merely to include the person in our private hall of flattering mirrors.

There is no such thing as a person whose real self you like every particle of. This is why a world of liking is ultimately a lie. But there is such a thing as a person whose real self you love every particle of. And this is why love is such an existential threat to the techno-consumerist order: it exposes the lie.

there’s virtually no scientific evidence that alternative medicine (anything from chiropractic care to acupuncture) has any curative benefit beyond a placebo effect. … However, there is one area where alternative medicine often trumps traditional medicine: stress reduction. And stress reduction can, of course, make a huge impact on people’s health. …

Maybe each of these activities (listening to high end audio gear, drinking high end wine, having needles inserted into your chakras) is really about ritualizing a sensory experience. By putting on headphones you know are high quality, or drinking expensive wine, or entering the chiropractor’s office, you are telling yourself, “I am going to focus on this moment. I am going to savor this.” It’s the act of savoring, rather than the savoring tool, that results in both happiness and a longer life.

Faced with growing ecological and social crises, and with advertising being the engine of an unsustainable and detrimental economic system, we have to manifest alternative values that will provide a humane, collective solution to these global crises.

These studies are finally proving what many have suspected for decades: advertising affects and normalises

It is easier to fool a person than it is to convince a person that they’ve been fooled. This is one of the great curses of humanity.

Given the incredible amount of information we process each day, it is difficult for any of us to critically analyze all of it.

The state of Minnesota is battling a measles outbreak caused by anti-vaccination propaganda. And Discussion over the effects of misinformation on recent elections in Austria, Germany, and the United States is still ongoing.

The alarming headlines came quickly Wednesday morning: “Now It’s Getting Serious: 2017 Could See a Bacon Shortage.”

The source of the anxiety was a recent report from the U.S.D.A., boosted by the Ohio Pork Council, which reported that the country’s frozen pork belly inventory was at its lowest point in half a century.

To create a panic “was not our intent,” Mr. Deaton added with a laugh. “We can’t control how the news is interpreted.”

How did Donald Trump win the Republican nomination, despite clear evidence that he had misrepresented or falsified key issues throughout the campaign? Social scientists have some intriguing explanations for why people persist in misjudgments despite strong contrary evidence.

When critics challenge false assertions — say, Trump’s claim that thousands of Muslims cheered in New Jersey when the twin towers fell on Sept. 11, 2001 — their refutations can threaten people, rather than convince them. Graves noted that if people feel attacked, they resist the facts all the more

Graves’s article examined the puzzle of why nearly one-third of U.S. parents believe that childhood vaccines cause autism, despite overwhelming medical evidence that there’s no such link. In such cases, he noted, “arguing the facts doesn’t help — in fact, it makes the situation worse.” The reason is that people tend to accept arguments that confirm their views and discount facts that challenge what they believe.

DONALD TRUMP is our first post-truth president. And he may well be the first of many.

The Oxford Dictionaries website chose “post-truth” as its 2016 word of the year, in large part due to Trump’s success in the presidential election. It defined post-truth as “relating to or denoting circumstances in which objective facts are less influential in shaping public opinion than appeals to emotion and personal belief.”

Over the last week, two of the world’s biggest internet companies have faced mounting criticism over how fake news on their sites may have influenced the presidential election’s outcome.

Hours later, Facebook, the social network, updated the language in its Facebook Audience Network policy, which already says it will not display ads in sites that show misleading or illegal content, to include fake news sites.

Google did not escape the glare, with critics saying the company gave too much prominence to false news stories.

A variety of methods have been developed over the past few decades to allow mapping of the functioning human brain. Two basic classes of mapping technique have evolved: those that map (or localise) the underlying electrical activity of the brain; and those that map local physiological or metabolic consequences of altered brain electrical activity. Among the former are the non-invasive neural electromagnetic techniques of electroencephalography (EEG) and magnetoencephalography (MEG). These methods allow exquisite temporal resolution of neural processes (typically over a 10–100 ms time scale), but suffer from poor spatial resolution (between 1 and several centimetres). Functional MRI (fMRI) methods are in the second category. They can be made sensitive to the changes in regional blood perfusion, blood volume (for example, using injected magnetic resonance contrast agents), or blood oxygenation that accompany neuronal activity. Blood oxygenation level dependent (BOLD) fMRI, which is sensitive primarily to the last of these variables, allows an image spatial resolution that is of the order of a few millimetres, with a temporal resolution of a few seconds (limited by the haemodynamic response itself). An accessible and more detailed introduction to the technique than is possible in this brief review is found in a recent book.1

Methods such as positron emission tomography (PET) provide an absolute measure of tissue metabolism. In contrast, BOLD fMRI can at present be used only for determining relative signal intensity changes associated with different cognitive states during a single imaging session. The most time efficient approach for comparing brain responses in different states during the imaging experiment is the “block” design19 (fig 3). This design uses relatively long alternating periods (for example, 30 seconds), during each of which a discrete cognitive state is maintained. In the simplest form, there may only be two such states, which are alternated throughout the experiment in order to ensure that variations arising from fluctuations in scanner sensitivity, patient movement, or changes in attention have a similar impact on the signal responses associated with both states.

By treating them as the same, we miss nuances that are important for understanding human decision-making.

Biases—regardless of whether they are hardwired into us due to evolution, learned through socialization or direct experience—or a function of genetically influenced traits, represent predispositions to favor a given conclusion over other conclusions. Therefore, biases might be considered the leanings, priorities, and inclinations that influence our decisions[2].

Heuristics are mental shortcuts that allow us to make decisions more quickly, frugally, and/or accurately than if we considered additional information. They are derived from experience and formal learning and are open to continuous updates based on new experiences and information. Therefore, heuristics represent the strategies we employ to filter and attend to information[3].

Do heuristics, the shortcuts that the brain takes, support efficient decision making or does it impede efficient decision making?

Humans have neither unlimited resources nor unlimited time to take decisions. So, the brain has always developed smart heuristics, shortcuts to take efficient decisions.

One other key thought put forward by Gigerenzer is that there is a big difference between risk and uncertainty. We are dealing with risk when you know all the alternatives, outcomes and their probabilities. We are dealing with uncertainty when you don’t know all the alternatives, outcomes or their probabilities.

Facebook released a statement on Wednesday stating that regrettably it was abandoning its plans to “significantly increase our investments with local publishers” and instead pulled the plug. Google meanwhile has managed to sidestep the proposition of a “link tax” by delivering the government’s objective of lucrative deals with Australian media companies from News Corp down to the smallest publishers. By flexing a little Google has for now avoided mandatory payment arbitration.

Governments have arguably not paid nearly enough attention to producing alternative digital solutions to giant centralised advertising companies that provide an increasing number of communication services for their citizens. Facebook’s petulance has inadvertently made a case in Australia for more regulation rather than less.

News organisations need to develop alternative platforms, and governments need to provide more regulated certainty. Highly digital newsrooms that have resources and strong relationships with their audiences started moving away from Facebook a long time ago, and are less affected by its volatility.

By Scientism, I mean three interrelated ideas that, taken together, stand as one of the pillars of Technopoly.

The first and indispensable idea is, as noted, that the methods of the natural sciences can be applied to the study of human behavior. This idea is the backbone of much of psychology and sociology as practiced at least in America, and largely accounts for the fact that social science, to quote F. A. Hayek, "has cont~ibuted scarcely anything to our understanding of social phenomena." 2

The second idea is, as also noted, that social science generates specific principles which can be used to organize society on a rational and humane basis. This implies that technical meansmostly "invisible technologies" supervised by experts-can be designed to control human behavior and set it on the proper course.

“Personal space” and the idea of being left alone with one’s thoughts can almost be seen as modern add-ons to what humanity is like, and perhaps more typical of WEIRD (Western, educated, industrialized, rich and democratic) societies than others

WEIRD-ness being the coinage of Joseph Henrich, an anthropologist at Harvard and the author of “The WEIRDest People in the World: How the West Became Psychologically Peculiar and Particularly Prosperous.” Reviewing the book for The Times, the Tufts University philosophy professor Daniel Dennett described Henrich’s concept thusly:The world today has billions of inhabitants who have minds strikingly different from ours. Roughly, we weirdos are individualistic, think analytically, believe in free will, take personal responsibility, feel guilt when we misbehave and think nepotism is to be vigorously discouraged, if not outlawed.

They (the non-WEIRD majority) identify more strongly with family, tribe, clan and ethnic group, think more “holistically,” take responsibility for what their group does (and publicly punish those who besmirch the group’s honor), feel shame — not guilt — when they misbehave and think nepotism is a natural duty.

What the party really needs, much more than a better identity-politics pitch, is an economic message that would appeal across demographic lines — reaching both downscale white voters turned off by Romney’s Bain Capital background and upwardly mobile Latino voters who don’t relate to the current G.O.P. fixation on upper-bracket tax cuts. As the American Enterprise Institute’s Henry Olsen writes, it should be possible for Republicans to oppose an overweening and intrusive state while still recognizing that “government can give average people a hand up to achieve the American Dream.” It should be possible for the party to reform and streamline government while also addressing middle-class anxieties about wages, health care, education and more. The good news is that such an agenda already exists, at least in embryonic form. Thanks to four years of intellectual ferment, Republicans seeking policy renewal have a host of thinkers and ideas to draw from: Luigi Zingales and Jim Pethokoukis on crony capitalism, Ramesh Ponnuru and Robert Stein on tax policy, Frederick Hess on education reform, James Capretta on alternatives to Obamacare, and many more.

It has been suggested, here and elsewhere, that Fox News effectively became part of the Republican propaganda apparatus during the presidential campaign by giving pundit slots to many of the Republican candidates and relentlessly advocating for Mitt Romney once he won the nomination. Over many months, Fox lulled its conservative base with agitprop: that President Obama was a clear failure, that a majority of Americans saw Mr. Romney as a good alternative in hard times, and that polls showing otherwise were politically motivated and not to be believed. But on Tuesday night, the people in charge of Fox News were confronted with a stark choice after it became clear that Mr. Romney had fallen short: was Fox, first and foremost, a place for advocacy or a place for news?