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Javier E

Global Warming 'Hiatus' Challenged by NOAA Research - NYTimes.com - 0 views

  • Scientists have long labored to explain what appeared to be a slowdown in global warming that began at the start of this century as, at the same time, heat-trapping emissions of carbon dioxide were soaring. The slowdown, sometimes inaccurately described as a halt or hiatus, became a major talking point for people critical of climate science.
  • When adjustments are made to compensate for recently discovered problems in the way global temperatures were measured, the slowdown largely disappears, the National Oceanic and Atmospheric Administration declared in a scientific paper published Thursday. And when the particularly warm temperatures of 2013 and 2014 are averaged in, the slowdown goes away entirely, the agency said.
  • “The notion that there was a slowdown in global warming, or a hiatus, was based on the best information we had available at the time,” said Thomas R. Karl, director of the National Centers for Environmental Information, a NOAA unit in Asheville, N.C. “Science is always working to improve.”
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  • senior climate scientists at other agencies were in no hurry to embrace NOAA’s specific adjustments. Several of them said it would take months of discussion in the scientific community to understand the data corrections and come to a consensus about whether to adopt them broadly.
  • NOAA said the improvements in its data set included the addition of a huge number of land measurements from around the world, as a result of improving international cooperation in sharing weather records. But the disappearance of the slowdown comes largely from adjustments in ocean temperatures.
  • A leading hypothesis to explain the slowdown is that natural fluctuations in the Pacific Ocean may have temporarily pulled some heat out of the atmosphere, producing a brief flattening in the long-term increase of surface temperatures.
  • Yet the temperature record is plagued by many problems: thermometers and recording practices changed through time, weather stations were moved, cities grew up around once-rural stations, and so on. Entire scientific careers are devoted to studying these issues and making corrections.
  • NOAA is one of four agencies around the world that attempts to produce a complete record of global temperatures dating to 1880. They all get similar results, showing a long-term warming of the planet that scientists have linked primarily to the burning of fossil fuels and the destruction of forests. A huge body of physical evidence — notably, that practically every large piece of land ice on the planet has started to melt — suggests the temperature finding is correct.
  • ocean measurements in particular are rife with difficulties.
  • Even if the warming slowdown in the early 21st century was real, there seems to be little question that it is ending. By a small margin, the global temperature hit a record in 2014, and developing weather patterns suggest that record will likely be broken by a larger margin in 2015.
carolinewren

Journalists debunk vaccine science denial - 0 views

  • extra difficulties imposed irrationally by antiscience.
  • Large outbreaks in the U.S. of the highly infectious disease have become more common in the past two years, even though measles hasn’t been indigenous since 2000, according to the Centers for Disease Control and Prevention.
  • difficult because concerns about a possible link between vaccines and autism—now debunked by science—have expanded to more general, and equally groundless, worries about the effects of multiple shots on a child’s immune system, vaccine experts and doctors say.
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  • It summarized and condemned the scientific and medical fraud that the British researcher Andrew Wakefield perpetrated. Years earlier, he had falsely linked the measles, mumps, and rubella (MMR) vaccine to autism. The editorial lamented that “the damage to public health continues, fuelled by unbalanced media reporting and an ineffective response from government, researchers, journals, and the medical profession.”
  • Reporters also seek to ensure that viewers, listeners, or readers understand that measles can afflict a victim more powerfully than does a mere passing ailment.
  • Measles doesn’t spread in most U.S. communities because people are protected by “herd immunity,” meaning that 92% to 94% of the population is vaccinated or immune. That level of protection makes it hard for one case of measles to spread even from one unvaccinated person to another without direct contact.
  • a study that “found that only 51 percent of Americans were confident that vaccines are safe and effective, which is similar to the proportion who believe that houses can be haunted by ghosts.”
  • In some parts of California, resistance to vaccinations including the MMR shot is stronger than ever, despite cases of measles hitting five US states.
  • “Vaccines are a great idea, but they are poisoning us, adding things that kick in later in life so they can sell us more drugs.”
  • Health professionals say those claims are unfounded or vastly overstated.
  • “the anti-vaccination movement is fueled by an over-privileged group of rich people grouped together who swear they won’t put any chemicals in their kids (food or vaccines or whatever else), either because it’s trendy to be all-natural or they don’t understand or accept the science of vaccinations. Their science denying has been propelled further by celebrities
  • the outbreak “should worry and enrage the public.” It indicted the anti-vaxxers’ “ignorant and self-absorbed rejection of science” and declared, “Getting vaccinated is good for the health of the inoculated person and also part of one’s public responsibility to help protect the health of others.”
  • “It’s wrong,” the editors emphasized, “to allow public health to be threatened while everyone else waits for these science-denying parents to open their eyes.”
  • “It’s because these people are highly educated and they get on the Internet and read things and think they can figure things out better than their physician.”
  • linked vaccination opposition to the “political left, which has long been suspicious of the lobbying power of the pharmaceutical industry and its influence on government regulators, and also the fringe political right, which has at different times seen vaccination, fluoridisation and other public-health initiatives as attempts by big government to impose tyrannical limits on personal freedom.”
  • Attempts to increase concerns about communicable diseases or correct false claims about vaccines may be especially likely to be counterproductive.
  • “attempting balance by giving vaccine skeptics and pro-vaccine advocates equal weight in news stories leads people to believe the evidence for and against vaccination is equally strong.”
  • A recent edition of the Washington Post carried a letter defending anti-vaxxers as “people who generally are pro-science and highly educated, who have high incomes and who have studied this issue carefully before coming to the conclusion that the risk to their children is greater than the slim possibility of contracting a childhood disease that [in many cases leaves] little or no residual consequences.”
  • anecdotal evidence suggests that some journalists, rather than omitting anti-vaxxers’ views, prefer to expose them and then oppose them.
  • “unwarranted fear . . . an assault on one of the greatest public-health inventions in world history.”
Sophia C

When Studies Are Wrong: A Coda - NYTimes.com - 0 views

  • All scientific results are, of course, subject to revision and refutation by later experiments. The problem comes when these replications don’t occur and the information keeps spreading unchecked. Continue reading the main story Related Coverage Raw Data: Hills to Scientific Discoveries Grow SteeperFEB. 17, 2014 Raw Data: New Truths That Only One Can SeeJAN. 20, 2014 D
  • Based on the number of papers in major journals, Dr. Ioannidis estimates that the field accounts for some 50 percent of published research.
  • Together that constitutes most of scientific research. The remaining slice is physical science — everything from geology and climatology to cosmology and particle physics. These fields have not received the same kind of scrutiny as the others. Is that because they are less prone to the problems Dr. Ioannides describe
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  • “This certainly increases the transparency, reliability and cross-checking of proposed research findings,” he wrote.
  • “There seems to be a higher community standard for ‘shaming’ reputations if people step out and make claims that are subsequently refuted.” Cold fusion was a notorious example. He also saw less of an aversion to publishing negative experimental results — that is, failed replications.
  • Almost anything might be suspected of causing cancer, but physicists are unlikely to propose conjectures that violate quantum mechanics or general relativity. But I’m not sure the difference is always that stark. Here is how I put it my blog post:
  • “I have no doubt that false positives occur in all of these fields,” he concluded, “and occasionally they may be a major problem.”I’ll be looking further into this matter for a future column and would welcome comments from scientists about the situation in their own domain.
  • problem comes when these replications don’t occur and the information keeps spreading unchecked.
carolinewren

Politicians, others on right, left challenge scientific consensus on some issues | The ... - 0 views

  • Often, pronouncements about either subject are accompanied by the politician’s mea culpa: “I’m not a scientist, but ... ”
  • It’s the butthat has caused heartburn among scientists, many of whom say such skepticism has an impact on public policy.
  • “They’ve been using it as if they can dismiss the view of scientists, which doesn’t make any sense,”
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  • ‘Well, I’m not an engineer, but I think the bridge will stand up.’  ”
  • “Not just as a public figure, but as a human being, your fidelity should be to reality and to the truth,”
  • Among those agreeing that climate change is both real and a man-made threat are the Intergovernmental Panel on Climate Change, NASA, the National Academy of Sciences, the Defense Department, the American Association for the Advancement of Science and the American Meteorological Society
  • giving parents a “measure of choice” on vaccination is “the balance that government has to decide.”
  • murkiness of those comments caused alarm among public-health officials, who say the impact of the anti-vaccination movement is being seen in a measles outbreak in a number of states and Washington, D.C.
  • Climate change also sparks tension.
  • He said he was galled by U.S. Sen. Rand Paul’s recent assertion that the government should not require parents to vaccinate their children because it’s an issue of “freedom.”
  • “There is an unwritten litmus test for GOP officeholders” to express some form of skepticism about the phenomenon, he said.
  • However, Cruz, Rubio, Portman and Paul all voted against another amendment that said human activity contributes “significantly” to the threat. Cruz has asserted to the National Journal that climate change is “a theory that can’t be proven or disproven.”
  • In a separate vote, 98 senators — including Cruz, Rubio, Portman and Paul — acknowledged that climate change is “real and not a hoax.”
  • The group that denied climate change is occurring has pivoted, acknowledging that it exists. Still, the group questions whether it is a man-made phenomenon.
  • As for the caveat I’m not a scientist, “What they’re saying they implicitly think is that scientists don’t even know about climate change,”
  • Conservatives felt more negative emotions when they read scientific studies that challenged their views on climate change and evolution than liberals did in reading about nuclear power and fracking, but researchers believe that’s because climate change and evolution are more national in scope than the issues picked for liberals.
  • “The point is, to a very high level, scientists do know.”
  • Even those who agree that climate change is real and is man-made might not support government action
  • He said the disconnect between the public and scientists isn’t necessarily a bad thing
  • Such a slowdown “gives the science time to mature on some of these issues.”
  • most would-be candidates want to appeal to as many people as possible.
  • “And if you can sort of try to obscure your actual position but not offend anyone, that’s what I think they try to do,”
  • But it’s possible that their comments reflect a growing disconnect between the views of the public and the scientific community.
  • 86 percent of scientists who are members of the American Association for the Advancement of Science said childhood vaccines such as the one for measles-mumps-rubella should be required, 68 percent of U.S. adults agreed.
  • larger gap on the subject of climate change: 87 percent of the scientists said climate change is caused mostly by human activity, while 50 percent of U.S. adults did.
  • The divide is not necessarily a conservative one
  • For example, while 88 percent of scientists said it is generally safe to eat genetically modified foods, only 37 percent of U.S. adults agreed.
  • And the vaccine issue is one that has united some liberals, the religious right and libertarians.
  • The study found that conservatives tend to distrust science on issues such as climate change and evolution. For liberals, it is fracking and nuclear power.
  • didn’t stop 39 Republicans — including GOP presidential contenders Sens. Ted Cruz, R-Texas, and Marco Rubio, R-Fla. — from opposing an amendment last month that blamed changing global temperatures on human activity.
  • liberals showed some distrust about science when they read about climate change and evolution
  • “Liberals can be just as biased as conservatives,” he said.
  • Rosenberg said the Internet can provide affirmation of pre-existing beliefs rather than encouraging people to find objective sources of information, such as peer-reviewed journals.
  • Often, attacking science is the easiest way to justify inaction, Rosenberg said.
fischerry

People have no idea which sciences are robust | Ars Technica - 1 views

  • People have no idea which sciences are robust
  • If there’s one thing everyone needs to understand about science, it’s that science is uncertain. It’s a process of gradually getting closer to the truth, with self-correcting mechanisms built in. Unfortunately, communicating this uncertainty without undermining trust in science is tricky.
  •  
    Relates to my essay.
Javier E

Reasons for COVID-19 Optimism on T-Cells and Herd Immunity - 0 views

  • It may well be the case that some amount of community protection kicks in below 60 percent exposure, and possibly quite a bit below that threshold, and that those who exhibit a cross-reactive T-cell immune response, while still susceptible to infection, may also have some meaningful amount of protection against severe disease.
  • early returns suggest that while the maximalist interpretation of each hypothesis is not very credible — herd immunity has probably not been reached in many places, and cross-reactive T-cell response almost certainly does not functionally immunize those who have it — more modest interpretations appear quite plausible.
  • Friston suggested that the truly susceptible portion of the population was certainly not 100 percent, as most modelers and conventional wisdom had it, but a much smaller share — surely below 50 percent, he said, and likely closer to about 20 percent. The analysis was ongoing, he said, but, “I suspect, once this has been done, it will look like the effective non-susceptible portion of the population will be about 80 percent. I think that’s what’s going to happen.”
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  • one of the leading modelers, Gabriela Gomes, suggested the entire area of research was being effectively blackballed out of fear it might encourage a relaxation of pandemic vigilance. “This is the very sad reason for the absence of more optimistic projections on the development of this pandemic in the scientific literature,” she wrote on Twitter. “Our analysis suggests that herd-immunity thresholds are being achieved despite strict social-distancing measures.”
  • Gomes suggested, herd immunity could happen with as little as one quarter of the population of a community exposed — or perhaps just 20 percent. “We just keep running the models, and it keeps coming back at less than 20 percent,” she told Hamblin. “It’s very striking.” Such findings, if they held up, would be very instructive, as Hamblin writes: “It would mean, for instance, that at 25 percent antibody prevalence, New York City could continue its careful reopening without fear of another major surge in cases.”
  • But for those hoping that 25 percent represents a true ceiling for pandemic spread in a given community, well, it almost certainly does not, considering that recent serological surveys have shown that perhaps 93 percent of the population of Iquitos, Peru, has contracted the disease; as have more than half of those living in Indian slums; and as many as 68 percent in particular neighborhoods of New York City
  • overshoot of that scale would seem unlikely if the “true” threshold were as low as 20 or 25 percent.
  • But, of course, that threshold may not be the same in all places, across all populations, and is surely affected, to some degree, by the social behavior taken to protect against the spread of the disease.
  • we probably err when we conceive of group immunity in simplistically binary terms. While herd immunity is a technical term referring to a particular threshold at which point the disease can no longer spread, some amount of community protection against that spread begins almost as soon as the first people are exposed, with each case reducing the number of unexposed and vulnerable potential cases in the community by one
  • you would not expect a disease to spread in a purely exponential way until the point of herd immunity, at which time the spread would suddenly stop. Instead, you would expect that growth to slow as more people in the community were exposed to the disease, with most of them emerging relatively quickly with some immune response. Add to that the effects of even modest, commonplace protections — intuitive social distancing, some amount of mask-wearing — and you could expect to get an infection curve that tapers off well shy of 60 percent exposure.
  • Looking at the data, we see that transmissions in many severely impacted states began to slow down in July, despite limited interventions. This is especially notable in states like Arizona, Florida, and Texas. While we believe that changes in human behavior and changes in policy (such as mask mandates and closing of bars/nightclubs) certainly contributed to the decrease in transmission, it seems unlikely that these were the primary drivers behind the decrease. We believe that many regions obtained a certain degree of temporary herd immunity after reaching 10-35 percent prevalence under the current conditions. We call this 10-35 percent threshold the effective herd immunity threshold.
  • Indeed, that is more or less what was recently found by Youyang Gu, to date the best modeler of pandemic spread in the U.S
  • he cautioned again that he did not mean to imply that the natural herd-immunity level was as low as 10 percent, or even 35 percent. Instead, he suggested it was a plateau determined in part by better collective understanding of the disease and what precautions to take
  • Gu estimates national prevalence as just below 20 percent (i.e., right in the middle of his range of effective herd immunity), it still counts, I think, as encouraging — even if people in hard-hit communities won’t truly breathe a sigh of relief until vaccines arrive.
  • If you can get real protection starting at 35 percent, it means that even a mediocre vaccine, administered much more haphazardly to a population with some meaningful share of vaccination skeptics, could still achieve community protection pretty quickly. And that is really significant — making both the total lack of national coordination on rollout and the likely “vaccine wars” much less consequential.
  • At least 20 percent of the public, and perhaps 50 percent, had some preexisting, cross-protective T-cell response to SARS-CoV-2, according to one much-discussed recent paper. An earlier paper had put the figure at between 40 and 60 percent. And a third had found an even higher prevalence: 81 percent.
  • The T-cell story is similarly encouraging in its big-picture implications without being necessarily paradigm-changing
  • These numbers suggest their own heterogeneity — that different populations, with different demographics, would likely exhibit different levels of cross-reactive T-cell immune response
  • The most optimistic interpretation of the data was given to me by Francois Balloux, a somewhat contrarian disease geneticist and the director of the University College of London’s Genetics Institute
  • According to him, a cross-reactive T-cell response wouldn’t prevent infection, but would probably mean a faster immune response, a shorter period of infection, and a “massively” reduced risk of severe illness — meaning, he guessed, that somewhere between a third and three-quarters of the population carried into the epidemic significant protection against its scariest outcomes
  • the distribution of this T-cell response could explain at least some, and perhaps quite a lot, of COVID-19’s age skew when it comes to disease severity and mortality, since the young are the most exposed to other coronaviruses, and the protection tapers as you get older and spend less time in environments, like schools, where these viruses spread so promiscuously.
  • Balloux told me he believed it was also possible that the heterogeneous distribution of T-cell protection also explains some amount of the apparent decline in disease severity over time within countries on different pandemic timelines — a phenomenon that is more conventionally attributed to infection spreading more among the young, better treatment, and more effective protection of the most vulnerable (especially the old).
  • Going back to Youyang Gu’s analysis, what he calls the “implied infection fatality rate” — essentially an estimated ratio based on his modeling of untested cases — has fallen for the country as a whole from about one percent in March to about 0.8 percent in mid-April, 0.6 percent in May, and down to about 0.25 percent today.
  • even as we have seemed to reach a second peak of coronavirus deaths, the rate of death from COVID-19 infection has continued to decline — total deaths have gone up, but much less than the number of cases
  • In other words, at the population level, the lethality of the disease in America has fallen by about three-quarters since its peak. This is, despite everything that is genuinely horrible about the pandemic and the American response to it, rather fantastic.
  • there may be some possible “mortality displacement,” whereby the most severe cases show up first, in the most susceptible people, leaving behind a relatively protected population whose experience overall would be more mild, and that T-cell response may play a significant role in determining that susceptibility.
  • That, again, is Balloux’s interpretation — the most expansive assessment of the T-cell data offered to me
  • The most conservative assessment came from Sarah Fortune, the chair of Harvard’s Department of Immunology
  • Fortune cautioned not to assume that cross-protection was playing a significant role in determining severity of illness in a given patient. Those with such a T-cell response, she told me, would likely see a faster onset of robust response, yes, but that may or may not yield a shorter period of infection and viral shedding
  • Most of the scientists, doctors, epidemiologists, and immunologists I spoke to fell between those two poles, suggesting the T-cell cross-immunity findings were significant without necessarily being determinative — that they may help explain some of the shape of pandemic spread through particular populations, but only some of the dynamics of that spread.
  • he told me he believed, in the absence of that data, that T-cell cross-immunity from exposure to previous coronaviruses “might explain different disease severity in different people,” and “could certainly be part of the explanation for the age skew, especially for why the very young fare so well.”
  • the headline finding was quite clear and explicitly stated: that preexisting T-cell response came primarily via the variety of T-cells called CD4 T-cells, and that this dynamic was consistent with the hypothesis that the mechanism was inherited from previous exposure to a few different “common cold” coronaviruses
  • “This potential preexisting cross-reactive T-cell immunity to SARS-CoV-2 has broad implications,” the authors wrote, “as it could explain aspects of differential COVID-19 clinical outcomes, influence epidemiological models of herd immunity, or affect the performance of COVID-19 candidate vaccines.”
  • “This is at present highly speculative,” they cautioned.
Javier E

How a dose of MDMA transformed a white supremacist - BBC Future - 0 views

  • February 2020, Harriet de Wit, a professor of psychiatry and behavioural science at the University of Chicago, was running an experiment on whether the drug MDMA increased the pleasantness of social touch in healthy volunteers
  • The latest participant in the double-blind trial, a man named Brendan, had filled out a standard questionnaire at the end. Strangely, at the very bottom of the form, Brendan had written in bold letters: "This experience has helped me sort out a debilitating personal issue. Google my name. I now know what I need to do."
  • They googled Brendan's name, and up popped a disturbing revelation: until just a couple of months before, Brendan had been the leader of the US Midwest faction of Identity Evropa, a notorious white nationalist group rebranded in 2019 as the American Identity Movement. Two months earlier, activists at Chicago Antifascist Action had exposed Brendan's identity, and he had lost his job.
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  • "Go ask him what he means by 'I now know what I need to do,'" she instructed Bremmer. "If it's a matter of him picking up an automatic rifle or something, we have to intervene."
  • As he clarified to Bremmer, love is what he had just realised he had to do. "Love is the most important thing," he told the baffled research assistant. "Nothing matters without
  • When de Wit recounted this story to me nearly two years after the fact, she still could hardly believe it. "Isn't that amazing?" she said. "It's what everyone says about this damn drug, that it makes people feel love. To think that a drug could change somebody's beliefs and thoughts without any expectations – it's mind-boggling."
  • Over the past few years, I've been investigating the scientific research and medical potential of MDMA for a book called "I Feel Love: MDMA and the Quest for Connection in a Fractured World". I learnt how this once-vilified drug is now remerging as a therapeutic agent – a role it previously played in the 1970s and 1980s, prior to its criminalisation
  • He attended the notorious "Unite the Right" rally in Charlottesville and quickly rose up the ranks of his organisation, first becoming the coordinator for Illinois and then the entire Midwest. He travelled to Europe and around the US to meet other white nationalist groups, with the ultimate goal of taking the movement mainstream
  • some researchers have begun to wonder if it could be an effective tool for pushing people who are already somehow primed to reconsider their ideology toward a new way of seeing things
  • While MDMA cannot fix societal-level drivers of prejudice and disconnection, on an individual basis it can make a difference. In certain cases, the drug may even be able to help people see through the fog of discrimination and fear that divides so many of us.
  • in December 2021 I paid Brendan a visit
  • What I didn't expect was how ordinary the 31-year-old who answered the door would appear to be: blue plaid button-up shirt, neatly cropped hair, and a friendly smile.
  • Brendan grew up in an affluent Chicago suburb in an Irish Catholic family. He leaned liberal in high school but got sucked into white nationalism at the University of Illinois Urbana-Champaign, where he joined a fraternity mostly composed of conservative Republican men, began reading antisemitic conspiracy books, and fell down a rabbit hole of racist, sexist content online. Brendan was further emboldened by the populist rhetoric of Donald Trump during his presidential campaign. "His speech talking about Mexicans being rapists, the fixation on the border wall and deporting everyone, the Muslim ban – I didn't really get white nationalism until Trump started running for president," Brendan said.
  • If this comes to pass, MDMA – and other psychedelics-assisted therapy – could transform the field of mental health through widespread clinical use in the US and beyond, for addressing trauma and possibly other conditions as well, including substance use disorders, depression and eating disorders.
  • A group of anti-fascist activists published identifying information about him and more than 100 other people in Identity Evropa. He was immediately fired from his job and ostracised by his siblings and friends outside white nationalism.
  • When Brendan saw a Facebook ad in early 2020 for some sort of drug trial at the University of Chicago, he decided to apply just to have something to do and to earn a little money
  • At the time, Brendan was "still in the denial stage" following his identity becoming public, he said. He was racked with regret – not over his bigoted views, which he still held, but over the missteps that had landed him in this predicament.
  • About 30 minutes after taking the pill, he started to feel peculiar. "Wait a second – why am I doing this? Why am I thinking this way?" he began to wonder. "Why did I ever think it was okay to jeopardise relationships with just about everyone in my life?"
  • Just then, Bremmer came to collect Brendan to start the experiment. Brendan slid into an MRI, and Bremmer started tickling his forearm with a brush and asked him to rate how pleasant it felt. "I noticed it was making me happier – the experience of the touch," Brendan recalled. "I started progressively rating it higher and higher." As he relished in the pleasurable feeling, a single, powerful word popped into his mind: connection.
  • It suddenly seemed so obvious: connections with other people were all that mattered. "This is stuff you can't really put into words, but it was so profound," Brendan said. "I conceived of my relationships with other people not as distinct boundaries with distinct entities, but more as we-are-all-on
  • I realised I'd been fixated on stuff that doesn't really matter, and is just so messed up, and that I'd been totally missing the point. I hadn't been soaking up the joy that life has to offer."
  • Brendan hired a diversity, equity, and inclusion consultant to advise him, enrolled in therapy, began meditating, and started working his way through a list of educational books. S still regularly communicates with Brendan and, for his part, thinks that Brendan is serious in his efforts to change
  • "I think he is trying to better himself and work on himself, and I do think that experience with MDMA had an impact on him. It's been a touchstone for growth, and over time, I think, the reflection on that experience has had a greater impact on him than necessarily the experience itself."
  • Brendan is still struggling, though, to make the connections with others that he craves. When I visited him, he'd just spent Thanksgiving alone
  • He also has not completely abandoned his bigoted ideology, and is not sure that will ever be possible. "There are moments when I have racist or antisemitic thoughts, definitely," he said. "But now I can recognise that those kinds of thought patterns are harming me more than anyone else."
  • it's not without precedent. In the 1980s, for example, an acquaintance of early MDMA-assisted therapy practitioner Requa Greer administered the drug to a pilot who had grown up in a racist home and had inherited those views. The pilot had always accepted his bigoted way of thinking as being a normal, accurate reflection of the way things were. MDMA, however, "gave him a clear vision that unexamined racism was both wrong and mean," Greer says
  • Encouraging stories of seemingly spontaneous change appear to be exceptions to the norm, however, and from a neurological point of view, this makes sense
  • Research shows that oxytocin – one of the key hormones that MDMA triggers neurons to release – drives a "tend and defend" response across the animal kingdom. The same oxytocin that causes a mother bear to nurture her newborn, for example, also fuels her rage when she perceives a threat to her cub. In people, oxytocin likewise strengthens caregiving tendencies toward liked members of a person's in-group and strangers perceived to belong to the same group, but it increases hostility toward individuals from disliked groups
  • In a 2010 study published in Science, for example, men who inhaled oxytocin were three times more likely to donate money to members of their team in an economic game, as well as more likely to harshly punish competing players for not donating enough. (Read more: "The surprising downsides of empathy.")
  • According to research published this week in Nature by Johns Hopkins University neuroscientist Gül Dölen, MDMA and other psychedelics – including psilocybin, LSD, ketamine and ibogaine – work therapeutically by reopening a critical period in the brain. Critical periods are finite windows of impressionability that typically occur in childhood, when our brains are more malleable and primed to learn new things
  • Dölen and her colleagues' findings likewise indicate that, without the proper set and setting, MDMA and other psychedelics probably do not reopen critical periods, which means they will not have a spontaneous, revelatory effect for ridding someone of bigoted beliefs.
  • In the West, plenty of members of right-wing authoritarian political movements, including neo-Nazi groups, also have track records of taking MDMA and other psychedelics
  • This suggests, researchers write, that psychedelics are nonspecific, "politically pluripotent" amplifiers of whatever is going on in somebody's head, with no particular directional leaning "on the axes of conservatism-liberalism or authoritarianism-egalitarianism."
  • That said, a growing body of scientific evidence indicates that the human capacity for compassion, kindness, empathy, gratitude, altruism, fairness, trust, and cooperation are core features of our natures
  • As Emory University primatologist Frans de Waal wrote, "Empathy is the one weapon in the human repertoire that can rid us of the curse of xenophobia."
  • Ginsberg also envisions using the drug in workshops aimed at eliminating racism, or as a means of bringing people together from opposite sides of shared cultural histories to help heal intergenerational trauma. "I think all psychedelics have a role to play, but I think MDMA has a particularly key role because you're both expanded and present, heart-open and really able to listen in a new way," Ginsberg says. "That's something really powerful."
  • "If you give MDMA to hard-core haters on each side of an issue, I don't think it'll do a lot of good,"
  • if you start with open-minded people on both sides, then I think it can work. You can improve communications and build empathy between groups, and help people be more capable of analysing the world from a more balanced perspective rather than from fear-based, anxiety-based distrust."
  • In 2021, Ginsberg and Doblin were coauthors on a study investigating the possibility of using ayahuasca – a plant-based psychedelic – in group contexts to bridge divides between Palestinians and Israelis, with positive findings
  • "I kind of have a fantasy that maybe as we get more reacquainted with psychedelics, there could be group-based experiences that build community resiliency and are intentionally oriented toward breaking down barriers between people, having people see things from other perspectives and detribalising our society,
  • "But that's not going to happen on its own. It would have to be intentional, and – if it happens – it would probably take multiple generations."
  • Based on his experience with extremism, Brendan agreed with expert takes that no drug, on its own, will spontaneously change the minds of white supremacists or end political conflict in the US
  • he does think that, with the right framing and mindset, MDMA could be useful for people who are already at least somewhat open to reconsidering their ideologies, just as it was for him. "It helped me see things in a different way that no amount of therapy or antiracist literature ever would have done," he said. "I really think it was a breakthrough experience."
Javier E

The varieties of denialism | Scientia Salon - 1 views

  • a stimulating conference at Clark University about “Manufacturing Denial,” which brought together scholars from wildly divergent disciplines — from genocide studies to political science to philosophy — to explore the idea that “denialism” may be a sufficiently coherent phenomenon underlying the willful disregard of factual evidence by ideologically motivated groups or individuals.
  • the Oxford defines a denialist as “a person who refuses to admit the truth of a concept or proposition that is supported by the majority of scientific or historical evidence,” which represents a whole different level of cognitive bias or rationalization. Think of it as bias on steroids.
  • First, as a scientist: it’s just not about the facts, indeed — as Brendan showed data in hand during his presentation — insisting on facts may have counterproductive effects, leading the denialist to double down on his belief.
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  • if I think that simply explaining the facts to the other side is going to change their mind, then I’m in for a rude awakening.
  • As a philosopher, I found to be somewhat more disturbing the idea that denialism isn’t even about critical thinking.
  • what the large variety of denialisms have in common is a very strong, overwhelming, ideological commitment that helps define the denialist identity in a core manner. This commitment can be religious, ethnical or political in nature, but in all cases it fundamentally shapes the personal identity of the people involved, thus generating a strong emotional attachment, as well as an equally strong emotional backlash against critics.
  • To begin with, of course, they think of themselves as “skeptics,” thus attempting to appropriate a word with a venerable philosophical pedigree and which is supposed to indicate a cautiously rational approach to a given problem. As David Hume put it, a wise person (i.e., a proper skeptic) will proportion her beliefs to the evidence. But there is nothing of the Humean attitude in people who are “skeptical” of evolution, climate change, vaccines, and so forth.
  • Denialists have even begun to appropriate the technical language of informal logic: when told that a majority of climate scientists agree that the planet is warming up, they are all too happy to yell “argument from authority!” When they are told that they should distrust statements coming from the oil industry and from “think tanks” in their pockets they retort “genetic fallacy!” And so on. Never mind that informal fallacies are such only against certain background information, and that it is eminently sensible and rational to trust certain authorities (at the least provisionally), as well as to be suspicious of large organizations with deep pockets and an obvious degree of self-interest.
  • What commonalities can we uncover across instances of denialism that may allow us to tackle the problem beyond facts and elementary logic?
  • the evidence from the literature is overwhelming that denialists have learned to use the vocabulary of critical thinking against their opponents.
  • Another important issue to understand is that denialists exploit the inherently tentative nature of scientific or historical findings to seek refuge for their doctrines.
  • . Scientists have been wrong before, and doubtlessly will be again in the future, many times. But the issue is rather one of where it is most rational to place your bets as a Bayesian updater: with the scientific community or with Faux News?
  • Science should be portrayed as a human story of failure and discovery, not as a body of barely comprehensible facts arrived at by epistemic priests.
  • Is there anything that can be done in this respect? I personally like the idea of teaching “science appreciation” classes in high school and college [2], as opposed to more traditional (usually rather boring, both as a student and as a teacher) science instruction
  • Denialists also exploit the media’s self imposed “balanced” approach to presenting facts, which leads to the false impression that there really are two approximately equal sides to every debate.
  • This is a rather recent phenomenon, and it is likely the result of a number of factors affecting the media industry. One, of course, is the onset of the 24-hr media cycle, with its pernicious reliance on punditry. Another is the increasing blurring of the once rather sharp line between reporting and editorializing.
  • The problem with the media is of course made far worse by the ongoing crisis in contemporary journalism, with newspapers, magazines and even television channels constantly facing an uncertain future of revenues,
  • he push back against denialism, in all its varied incarnations, is likely to be more successful if we shift the focus from persuading individual members of the public to making political and media elites accountable.
  • This is a major result coming out of Brendan’s research. He showed data set after data set demonstrating two fundamental things: first, large sections of the general public do not respond to the presentation of even highly compelling facts, indeed — as mentioned above — are actually more likely to entrench further into their positions.
  • Second, whenever one can put pressure on either politicians or the media, they do change their tune, becoming more reasonable and presenting things in a truly (as opposed to artificially) balanced way.
  • Third, and most crucially, there is plenty of evidence from political science studies that the public does quickly rally behind a unified political leadership. This, as much as it is hard to fathom now, has happened a number of times even in somewhat recent times
  • when leaders really do lead, the people follow. It’s just that of late the extreme partisan bickering in Washington has made the two major parties entirely incapable of working together on the common ground that they have demonstrably had in the past.
  • Another thing we can do about denialism: we should learn from the detailed study of successful cases and see what worked and how it can be applied to other instances
  • Yet another thing we can do: seek allies. In the case of evolution denial — for which I have the most first-hand experience — it has been increasingly obvious to me that it is utterly counterproductive for a strident atheist like Dawkins (or even a relatively good humored one like yours truly) to engage creationists directly. It is far more effective when we have clergy (Barry Lynn of Americans United for the Separation of Church and State [6] comes to mind) and religious scientists
  • Make no mistake about it: denialism in its various forms is a pernicious social phenomenon, with potentially catastrophic consequences for our society. It requires a rallying call for all serious public intellectuals, academic or not, who have the expertise and the stamina to join the fray to make this an even marginally better world for us all. It’s most definitely worth the fight.
dicindioha

The Neuroscience of Illusion - Scientific American - 0 views

  • It is a fact of neuroscience that everything we experience is a figment of our imagination. Although our sensations feel accurate and truthful, they do not necessarily reproduce the physical reality of the outside world.
    • dicindioha
       
      I find it interesting that a part of science, that studies the brain, says it is a fact that reality is not what we perceive. This is a science of showing humans that the way we see the world comes from our own brains. Learning these things through neuroscience probably made other scientists want to move our progress of biology and other sciences even more forward to try and gain a better look at the world. Perception seems to be another problem on top of never being able to come to a proof of science.
  • In other words, the real and the imagined share a physical source in the brain. So take a lesson from Socrates: “All I know is that I know nothing.”
    • dicindioha
       
      This is a humorous quote, and although maybe a bit extreme, it reflects somewhat of the way I felt after our recent discussions about how what we know in science is just a theory that has not been disproved yet.
  • One of the most important tools used by neuroscientists to understand how the brain creates its sense of reality is the visual illusion. Historically, artists as well as researchers have used illusions to gain insights into the inner workings of the visual system.
    • dicindioha
       
      A way of studying the brain is tricking it.
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  • Because of this disconnect between perception and reality, visual illusions demonstrate the ways in which the brain can fail to re-create the physical world.
    • dicindioha
       
      I like that the concepts we talk about in TOK, or what I think of as a course about theories and knowledge, come up in areas of science. Then this translates to how I feel as if I trust science very much, and how this is okay, but I must remember that what is shown to the public is affected by the scientific community
carolinewren

Mess: Emotion can be good; science can be bad | Pork Network - 0 views

  • While facts and science are the backbone of what we do as agriculturalists, numbers and statistics tend to be dry and not very convincing when presented by someone who doesn’t first connect to the audience they are speaking
  • While the first two examples may stick in someone’s mind for a while, the third example, which brings emotions into the conversation, is the one that will get the most people riled up.
  • For some, it seems emotion is fine when we want people to understand us, but should be frowned upon when brought to us by our customers.
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  • there has been an uptick in the online discussion on what roll emotion plays in the art and science of raising animals.
  • The old saying that “people don’t care how much you know until they know how much you care” applies to agvocacy just as much as anything else. Animal rights activists gained ground because, rather than lead with the facts and figures, they tell stories that tug at the heartstrings of those who don’t know better.
  • Dropping science from the discussion saves time. Think of all the time it takes to spout off some numbers and paste a link to a study. We can use that time to truly listen to our customers and answer them with our own personal stories.
  • sticking with just the science of what we do is simply not effective. When it comes to talking about how we care for our land and animals, cutting corners straight to the facts and playing it safe hasn’t been working for us. We must show the softer side of farming.
ilanaprincilus06

Bringing genetics into trans identity is a terrifying path | Fury | Opinion | The Guardian - 0 views

  • This study was looking at the relationship between these genes and the possibility that they are a factor in what causes gender dysphoria.
  • By examining a link between genetics and gender dysphoria, this study is investigating a potential biological cause for the existence of transgender people.
  • “This is nothing new. These arguments have happened before with research into the ‘gay gene’ in the late 1980s and early 90s.”
    • ilanaprincilus06
       
      Have we found evidence of a "straight gene"? It is sad that the presumed assumption of everyone being born straight is still an ongoing argument.
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  • “In their study, they found that some of these gene variants were significantly more associated with being trans women, and not just being male. That doesn’t establish causality, and it is just an association. And in fact, its a weak association,”
  • genetic markers are not assumed to be the only factor in what shapes something like gender.
  • When publishing material that supports the idea that there is a biological element to gender identity, scientists, policy makers and the general public are less inclined to listen to trans activists.
  • Trans activists seek to educate people on their fundamental human right to experiment with dress, movement, identity and presentation.
  • “The way that science, technology and science is progressing can be incredibly dangerous in regards to things like eugenics.”
  • Until 2013, trans people in Sweden were required to undergo sterilization before they could access gender-affirming treatment.
  • Given the rising accessibility of gene testing, this sort of research can easily be weaponised as justification for sterilisation, persecution or the abortion of fetuses with these genes.
  • It also further troubles the tenuous relationship that the scientific and medical community have with the trans community.
  • Fostering the notion of a genetic factor to gender dysphoria threatens to further complicate trans people’s access to appropriate care.
  • it takes away their right to self determination and the right to bodily autonomy in regards to gender expression and creativity.”
  • raises questions about the repeated and unchecked power discrepancies between science, medicine and the trans and gender diverse community.
blythewallick

The quiet loss of knowledge threatens indigenous communities -- ScienceDaily - 0 views

  • Plants play an important role for most indigenous communities in South America, and not merely as a source of food. They also provide the raw material for building materials, tools, medicine, and much more. The extinction of a plant species therefore also endangers the very foundation of these people's way of life. advertisement
  • The problem is that this is not written down. Passed down as a cultural inheritance, it exists only in the minds of the people -- and could therefore vanish almost unnoticed. "Very little is known about how vulnerable this knowledge is in the context of current global change," says Jordi Bascompte, professor of ecology at the University of Zurich.
  • "There is therefore an urgent need to find out how biological and cultural factors interact with each other in determining the services provided by biodiversity.."
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  • For their study, they analyzed knowledge held by 57 indigenous communities in the Amazon basin, the Andes and the Chocó region to collate their knowledge of palm trees. The researchers then depicted the different palm species and their uses in graphical form in a network, from which they could identify the local and regional links between the knowledge of indigenous communities.
  • "In this context, cultural diversity is just as important as biological diversity," says Jordi Bascompte. "In particular, the simultaneous loss of plant species and cultural inheritance leads to a much faster disintegration of the indigenous knowledge network."
  • However, the irreplaceable knowledge that is gradually disappearing from indigenous communities is equally important for the service that an ecosystem provides."
  • The study also highlights the value of transdisciplinary collaboration between ecology and social science: "The relationship established between biological and cultural diversity can help strengthen the resilience of indigenous communities in the face of global change."
carolinewren

Smart Buildings: Architects Turn to Brain Science | Al Jazeera America - 0 views

  • The public middle school, which is part of a larger complex that includes Corona del Mar High School, now is attracting more students who would normally have gone to private school in this affluent Orange County district, said Principal Rebecca Gogel. “There has been a significant change in student behavior,” she said.
  • But what has gone into the design of this school goes much deeper than sheer aesthetics. Architects are now applying neuroscience to design schools, hospitals, community centers and even single-family homes.
  • meshing of architecture and brain science is starting to gain traction. Architects are studying the way the brain reacts to various environments through brain scanners and applying the findings to their designs.
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  • The role of neuroscience in architecture is a contemporary concept that attaches scientific proof, measurement and research to the design of buildings.
  • The brain controls behavior, and genes control the design and structure of the brain. Science shows that environment can modulate the function of genes and, ultimately, the structure of the brain. So if changes in the environment change behavior, architectural design can change it too.
  • It has a direct impact on wellness issues and a direct influence on activity within that space.”
  • science has proved that natural lighting stimulates positive brain function and helps students learn. “Visual access to sky, trees and landscape stimulates brain function,”
  • The research argues that not only do we need order but our brain likes hearing stories
  • According to the book, humans are a wall-hugging species that avoids the center of open spaces. People who are outside seem more comfortable when buildings create a roomlike feel, surrounding them on several sides, Hollander said.
  • People also respond more positively when they can identify a “face” in building design — windows as the eyes, doors as the mouth and so on.
  • “Humans have a clear bias for curves over straight or sharp lines,” Hollander said. Studies have shown that curves elicit “feelings of happiness and elation, while jagged and sharp forms tend to connect to feelings of pain and sadness.”
  • because the seat of power of the American president — the Oval Office — is curved, the room may carry a psychological advantage for its occupant.
  • bilateral symmetry that humans prefer, with the desk centered on its longer axis.
  • Neuroscience shows that light triggers brain reactions far beyond vision. “It has an impact on heart rate,” she said
  • “This is a human condition that affects our well-being,” Dougherty said. “Why not take the utmost advantage of our capabilities? … Hopefully, the days of windowless classrooms to prevent vandalism and distraction are over.”
kortanekev

How Animals Communicate Via Pheromones » American Scientist - 0 views

  • Pheromones are chemical signals that have evolved for communication between members of the same species. A pheromone signal elicits a specific reaction in the receiver, for example, a stereotyped behavior
  •  
    This article depicts an efficient and accurate form of communication that is not dynamic or abstract in any way like the languages we use. This form is pheromones which are chemicals that animals have evolved to secrete, receive, and respond to instinctively. Despite being a process that we can't control, it does serve as an effective communication that does not depend on our subjective deciphering.  (Evie 11/27/16)
Javier E

Our Elites Still Don't Get It - The New York Times - 0 views

  • John Bowlby is the father of attachment theory, which explains how humans are formed by relationships early in life, and are given the tools to go out and lead their lives
  • “All of us, from cradle to grave, are happiest when life is organized as a series of excursions, long or short, from the secure base provided by our attachment figures.”
  • The relationships that form you are mostly things you didn’t choose: your family, hometown, ethnic group, religion, nation and genes.
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  • The things you do with your life are mostly chosen: your job, spouse and hobbies.
  • At our foundation, we were a society with strong covenantal attachments — to family, community, creed and faith. Then on top of them we built democracy and capitalism that celebrated liberty and individual rights.
  • The deep covenantal institutions gave people the capacity to use their freedom well. The liberal institutions gave them that freedom.
  • This delicate balance — liberal institutions built atop illiberal ones — is now giving way. The big social movements of the past half century were about maximizing freedom of choice. Right-wingers wanted to maximize economic choice and left-wingers lifestyle choice. Anything that smacked of restraint came to seem like a bad thing to be eliminated.
  • We’ll call this worldview — which is all freedom and no covenant — naked liberalism
  • The problem with naked liberalism is that it relies on individuals it cannot create.
  • Naked liberals of right and left assume that if you give people freedom they will use it to care for their neighbors, to have civil conversations, to form opinions after examining the evidence. But if you weaken family, faith, community and any sense of national obligation, where is that social, emotional and moral formation supposed to come from? How will the virtuous habits form?
  • Naked liberalism has made our society an unsteady tree. The branches of individual rights are sprawling, but the roots of common obligation are withering away.
  • Freedom without covenant becomes selfishness. And that’s what we see at the top of society, in our politics and the financial crisis
  • In my experience, most people under 40 get this. They sense the social and moral void at the core and that change has to come at the communal, emotional and moral level.
  • And that’s what we see at the bottom of society — frayed communities, broken families, opiate addiction.
  • Freedom without a unifying national narrative becomes distrust, polarization and permanent political war.
  • covenantal attachments they become fragile. Moreover, if you rob people of their good covenantal attachments, they will grab bad ones.
  • First, they will identify themselves according to race. They will become the racial essentialists you see on left and right
  • Then they resort to tribalism. This is what Donald Trump provides. As Mark S. Weiner writes on the Niskanen Center’s blog, Trump is constantly making friend/enemy distinctions, exploiting liberalism’s thin conception of community and creating toxic communities based on in-group/out-group rivalry.
  • Trump offers people cultural solutions to their alienation problem. As history clearly demonstrates, people will prefer fascism to isolation, authoritarianism to moral anarchy.
  • If we are going to have a decent society we’re going to have to save liberalism from itself. We’re going to have to restore and re-enchant the covenantal relationships that are the foundation for the whole deal. The crucial battleground is cultural and prepolitical.
  • Freedom without connection becomes alienation.
  • Many public intellectuals were trained in the social sciences and take the choosing individual as their mental starting point. They have trouble thinking about our shared social and moral formative institutions and how such institutions could be reconstituted.
  • Congressional Republicans think a successful tax bill will thwart populism. Mainstream Democrats think the alienation problem will go away if we redistribute the crumbs a bit more widely.
  • History is full of examples of nations that built new national narratives, revived family life, restored community bonds and shared moral culture: Britain in the early 19th century, Germany after World War II, America in the Progressive Era. The first step in launching our own revival is understanding that the problem is down in the roots.
krystalxu

Developing Communication Language And Literacy Skills Education Essay - 0 views

  • They need to recognise the role of communication in our society and from birth they need many and varied opportunities for positive interaction, and responses to their attempts to express themselves.
  • Communication, Language and Literacy helps a child to understand relationships, to hear words and sentences.
  • Through their growing knowledge and understanding, children can learn to appreciate the contribution made by many cultures to the development and application of communication, language and literacy.
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  • Children learn different communication, language and literacy skills through a structure of literacy framework that are related to development.
  • The process tries to make children to enjoy communication, language and literacy and be enthusiastic about the learning it .
  • They develop understanding of the correspondence between spoken and written sounds and learn to link sounds and letters and use their knowledge to read and write simple words by sounding out and blending.
  • The development of a national infrastructure is capable of providing ongoing professional development, quality assurance and data collection for the intervention.
  • The observations should be shared with the group to help make improvements in future performances.
  • Observing and encouraging babies and children's use of mirrors for self exploration of facial expression and gesture.
  • At times it can be useful to encourage children to use their home language, for example when organising initial ideas.
  • New buildings should be physically accessible to disabled pupils and will involve improving access to existing buildings including ramps, wider doors, low sinks, etc
  • All opportunities need to be well grounded in positive pride for the styles common in every child's own background. 
Javier E

Silicon Valley's Safe Space - The New York Times - 0 views

  • The roots of Slate Star Codex trace back more than a decade to a polemicist and self-described A.I. researcher named Eliezer Yudkowsky, who believed that intelligent machines could end up destroying humankind. He was a driving force behind the rise of the Rationalists.
  • Because the Rationalists believed A.I. could end up destroying the world — a not entirely novel fear to anyone who has seen science fiction movies — they wanted to guard against it. Many worked for and donated money to MIRI, an organization created by Mr. Yudkowsky whose stated mission was “A.I. safety.”
  • The community was organized and close-knit. Two Bay Area organizations ran seminars and high-school summer camps on the Rationalist way of thinking.
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  • “The curriculum covers topics from causal modeling and probability to game theory and cognitive science,” read a website promising teens a summer of Rationalist learning. “How can we understand our own reasoning, behavior, and emotions? How can we think more clearly and better achieve our goals?”
  • Some lived in group houses. Some practiced polyamory. “They are basically just hippies who talk a lot more about Bayes’ theorem than the original hippies,” said Scott Aaronson, a University of Texas professor who has stayed in one of the group houses.
  • For Kelsey Piper, who embraced these ideas in high school, around 2010, the movement was about learning “how to do good in a world that changes very rapidly.”
  • Yes, the community thought about A.I., she said, but it also thought about reducing the price of health care and slowing the spread of disease.
  • Slate Star Codex, which sprung up in 2013, helped her develop a “calibrated trust” in the medical system. Many people she knew, she said, felt duped by psychiatrists, for example, who they felt weren’t clear about the costs and benefits of certain treatment.
  • That was not the Rationalist way.
  • “There is something really appealing about somebody explaining where a lot of those ideas are coming from and what a lot of the questions are,” she said.
  • Sam Altman, chief executive of OpenAI, an artificial intelligence lab backed by a billion dollars from Microsoft. He was effusive in his praise of the blog.It was, he said, essential reading among “the people inventing the future” in the tech industry.
  • Mr. Altman, who had risen to prominence as the president of the start-up accelerator Y Combinator, moved on to other subjects before hanging up. But he called back. He wanted to talk about an essay that appeared on the blog in 2014.The essay was a critique of what Mr. Siskind, writing as Scott Alexander, described as “the Blue Tribe.” In his telling, these were the people at the liberal end of the political spectrum whose characteristics included “supporting gay rights” and “getting conspicuously upset about sexists and bigots.”
  • But as the man behind Slate Star Codex saw it, there was one group the Blue Tribe could not tolerate: anyone who did not agree with the Blue Tribe. “Doesn’t sound quite so noble now, does it?” he wrote.
  • Mr. Altman thought the essay nailed a big problem: In the face of the “internet mob” that guarded against sexism and racism, entrepreneurs had less room to explore new ideas. Many of their ideas, such as intelligence augmentation and genetic engineering, ran afoul of the Blue Tribe.
  • Mr. Siskind was not a member of the Blue Tribe. He was not a voice from the conservative Red Tribe (“opposing gay marriage,” “getting conspicuously upset about terrorists and commies”). He identified with something called the Grey Tribe — as did many in Silicon Valley.
  • The Grey Tribe was characterized by libertarian beliefs, atheism, “vague annoyance that the question of gay rights even comes up,” and “reading lots of blogs,” he wrote. Most significantly, it believed in absolute free speech.
  • The essay on these tribes, Mr. Altman told me, was an inflection point for Silicon Valley. “It was a moment that people talked about a lot, lot, lot,” he said.
  • And in some ways, two of the world’s prominent A.I. labs — organizations that are tackling some of the tech industry’s most ambitious and potentially powerful projects — grew out of the Rationalist movement.
  • In 2005, Peter Thiel, the co-founder of PayPal and an early investor in Facebook, befriended Mr. Yudkowsky and gave money to MIRI. In 2010, at Mr. Thiel’s San Francisco townhouse, Mr. Yudkowsky introduced him to a pair of young researchers named Shane Legg and Demis Hassabis. That fall, with an investment from Mr. Thiel’s firm, the two created an A.I. lab called DeepMind.
  • Like the Rationalists, they believed that A.I could end up turning against humanity, and because they held this belief, they felt they were among the only ones who were prepared to build it in a safe way.
  • In 2014, Google bought DeepMind for $650 million. The next year, Elon Musk — who also worried A.I. could destroy the world and met his partner, Grimes, because they shared an interest in a Rationalist thought experiment — founded OpenAI as a DeepMind competitor. Both labs hired from the Rationalist community.
  • Mr. Aaronson, the University of Texas professor, was turned off by the more rigid and contrarian beliefs of the Rationalists, but he is one of the blog’s biggest champions and deeply admired that it didn’t avoid live-wire topics.
  • “It must have taken incredible guts for Scott to express his thoughts, misgivings and questions about some major ideological pillars of the modern world so openly, even if protected by a quasi-pseudonym,” he said
  • In late June of last year, not long after talking to Mr. Altman, the OpenAI chief executive, I approached the writer known as Scott Alexander, hoping to get his views on the Rationalist way and its effect on Silicon Valley. That was when the blog vanished.
  • The issue, it was clear to me, was that I told him I could not guarantee him the anonymity he’d been writing with. In fact, his real name was easy to find because people had shared it online for years and he had used it on a piece he’d written for a scientific journal. I did a Google search for Scott Alexander and one of the first results I saw in the auto-complete list was Scott Alexander Siskind.
  • More than 7,500 people signed a petition urging The Times not to publish his name, including many prominent figures in the tech industry. “Putting his full name in The Times,” the petitioners said, “would meaningfully damage public discourse, by discouraging private citizens from sharing their thoughts in blog form.” On the internet, many in Silicon Valley believe, everyone has the right not only to say what they want but to say it anonymously.
  • I spoke with Manoel Horta Ribeiro, a computer science researcher who explores social networks at the Swiss Federal Institute of Technology in Lausanne. He was worried that Slate Star Codex, like other communities, was allowing extremist views to trickle into the influential tech world. “A community like this gives voice to fringe groups,” he said. “It gives a platform to people who hold more extreme views.”
  • I assured her my goal was to report on the blog, and the Rationalists, with rigor and fairness. But she felt that discussing both critics and supporters could be unfair. What I needed to do, she said, was somehow prove statistically which side was right.
  • When I asked Mr. Altman if the conversation on sites like Slate Star Codex could push people toward toxic beliefs, he said he held “some empathy” for these concerns. But, he added, “people need a forum to debate ideas.”
  • In August, Mr. Siskind restored his old blog posts to the internet. And two weeks ago, he relaunched his blog on Substack, a company with ties to both Andreessen Horowitz and Y Combinator. He gave the blog a new title: Astral Codex Ten. He hinted that Substack paid him $250,000 for a year on the platform. And he indicated the company would give him all the protection he needed.
Javier E

The Constitution of Knowledge - Persuasion - 0 views

  • But ideas in the marketplace do not talk directly to each other, and for the most part neither do individuals.
  • It is a good metaphor as far as it goes, yet woefully incomplete. It conjures up an image of ideas being traded by individuals in a kind of flea market, or of disembodied ideas clashing and competing in some ethereal realm of their own
  • When Americans think about how we find truth amid a world full of discordant viewpoints, we usually turn to a metaphor, that of the marketplace of ideas
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  • Rather, our conversations are mediated through institutions like journals and newspapers and social-media platforms. They rely on a dense network of norms and rules, like truthfulness and fact-checking. They depend on the expertise of professionals, like peer reviewers and editors. The entire system rests on a foundation of values: a shared understanding that there are right and wrong ways to make knowledge.
  • Those values and rules and institutions do for knowledge what the U.S. Constitution does for politics: They create a governing structure, forcing social contestation onto peaceful and productive pathways.
  • I call them, collectively, the Constitution of Knowledge. If we want to defend that system from its many persistent attackers, we need to understand it—and its very special notion of reality.
  • What reality really is
  • The question “What is reality?” may seem either too metaphysical to answer meaningfully or too obvious to need answering
  • The whole problem is that humans have no direct access to an objective world independent of our minds and senses, and subjective certainty is no guarantee of truth. Faced with those problems and others, philosophers and practitioners think of reality as a set of propositions (or claims, or statements) that have been validated in some way, and that have thereby been shown to be at least conditionally true—true, that is, unless debunked
  • Some propositions reflect reality as we perceive it in everyday life (“The sky is blue”). Others, like the equations on a quantum physicist’s blackboard, are incomprehensible to intuition. Many fall somewhere in between.
  • a phrase I used a few sentences ago, “validated in some way,” hides a cheat. In epistemology, the whole question is, validated in what way? If we care about knowledge, freedom, and peace, then we need to stake a strong claim: Anyone can believe anything, but liberal science—open-ended, depersonalized checking by an error-seeking social network—is the only legitimate validator of knowledge, at least in the reality-based community.
  • That is a very bold, very broad, very tough claim, and it goes down very badly with lots of people and communities who feel ignored or oppressed by the Constitution of Knowledge: creationists, Christian Scientists, homeopaths, astrologists, flat-earthers, anti-vaxxers, birthers, 9/11 truthers, postmodern professors, political partisans, QAnon followers, and adherents of any number of other belief systems and religions.
  • But, like the U.S. Constitution’s claim to exclusivity in governing (“unconstitutional” means “illegal,” period), the Constitution of Knowledge’s claim to exclusivity is its sine qua non.
  • Rules for reality
  • The specific proposition does not matter. What does matter is that the only way to validate it is to submit it to the reality-based community. Otherwise, you could win dominance for your proposition by, say, brute force, threatening and jailing and torturing and killing those who see things differently—a standard method down through history
  • Say you believe something (X) to be true, and you believe that its acceptance as true by others is important or at least warranted
  • Or you and your like-minded friends could go off and talk only to each other, in which case you would have founded a cult—which is lawful but socially divisive and epistemically worthless.
  • Or you could engage in a social-media campaign to shame and intimidate those who disagree with you—a very common method these days, but one that stifles debate and throttles knowledge (and harms a lot of people).
  • What the reality-based community does is something else again. Its distinctive qualities derive from two core rules: 
  • what counts is the way the rule directs us to behave: You must assume your own and everyone else’s fallibility and you must hunt for your own and others’ errors, even if you are confident you are right. Otherwise, you are not reality-based.
  • The fallibilist rule: No one gets the final say. You may claim that a statement is established as knowledge only if it can be debunked, in principle, and only insofar as it withstands attempts to debunk it.
  • The empirical rule: No one has personal authority. You may claim that a statement has been established as knowledge only insofar as the method used to check it gives the same result regardless of the identity of the checker, and regardless of the source of the statement
  • Who you are does not count; the rules apply to everybody and persons are interchangeable. If your method is valid only for you or your affinity group or people who believe as you do, then you are not reality-based.
  • Whatever you do to check a proposition must be something that anyone can do, at least in principle, and get the same result. Also, no one proposing a hypothesis gets a free pass simply because of who she is or what group she belongs to.
  • Both rules have very profound social implications. “No final say” insists that to be knowledge, a statement must be checked; and it also says that knowledge is always provisional, standing only as long as it withstands checking.
  • “No personal authority” adds a crucial second step by defining what properly counts as checking. The point, as the great American philosopher Charles Sanders Peirce emphasized more than a century ago, is not that I look or you look but that we look; and then we compare, contest, and justify our views. Critically, then, the empirical rule is a social principle that forces us into the same conversation—a requirement that all of us, however different our viewpoints, agree to discuss what is in principle only one reality.
  • By extension, the empirical rule also dictates what does not count as checking: claims to authority by dint of a personally or tribally privileged perspective.
  • In principle, persons and groups are interchangeable. If I claim access to divine revelation, or if I claim the support of miracles that only believers can witness, or if I claim that my class or race or historically dominant status or historically oppressed status allows me to know and say things that others cannot, then I am breaking the empirical rule by exempting my views from contestability by others.
  • Though seemingly simple, the two rules define a style of social learning that prohibits a lot of the rhetorical moves we see every day.
  • Claiming that a conversation is too dangerous or blasphemous or oppressive or traumatizing to tolerate will almost always break the fallibilist rule.
  • Claims which begin “as a Jew,” or “as a queer,” or for that matter “as minister of information” or “as Pope” or “as head of the Supreme Soviet,” can be valid if they provide useful information about context or credentials; but if they claim to settle an argument by appealing to personal or tribal authority, rather than earned authority, they violate the empirical rule. 
  • “No personal authority” says nothing against trying to understand where people are coming from. If we are debating same-sex marriage, I may mention my experience as a gay person, and my experience may (I hope) be relevant.
  • But statements about personal standing and interest inform the conversation; they do not control it, dominate it, or end it. The rule acknowledges, and to an extent accepts, that people’s social positions and histories matter; but it asks its adherents not to burrow into their social identities, and not to play them as rhetorical trump cards, but to bring them to the larger project of knowledge-building and thereby transcend them.
  • the fallibilist and empirical rules are the common basis of science, journalism, law, and all the other branches of today’s reality-based community. For that reason, both rules also attract hostility, defiance, interference, and open warfare from those who would rather manipulate truth than advance it.
johnsonel7

Sensory perception | Science Features | Naked Scientists - 0 views

  • Deciphering how the brain processes sight and hearing could have implications for how we understand and treat conditions such as dyslexia, autism and schizophrenia.
  • schizophrenia
  • Through a project called SENSOCOM, she is exploring how sensory perception affects communication, focusing on the brain’s deep subcortical structures.By doing this, she and her team are exploring a part of the brain traditionally excluded by research trying to understand communication impairments found in autism spectrum disorder and dyslexia, conditions which affect around 53 million people in Europe.
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  • To do this they have been focusing on the sensory pathways linked to these deep structures. She and her group discovered that adults with dyslexia have weaker pathway connections between a visual subcortical structure (the left visual thalamus) with an area of the cortex called V5/MT, which is critical for the perception of visual motion. In the auditory mode, there was a similar finding. The team discovered weaker connections between the left auditory thalamus and a cortex structure linked to auditory motion, which is important for speech perception. These connections could therefore be important for reading and for predicting reading skill, according to Dr von Kriegstein.
  • So how might this translate into helping people with dyslexia? This is basic science, says Prof. von Kriegstein, so first it’s crucial to understand the mechanisms behind communications disorders before developing therapy training tools, although she is optimistic these could lie within reach.
  • The way the brain encodes information and in turn directs perception of that sensory experience is a highly variable process.
  • The sensory overload or distorted and heightened perceptions described by schizophrenia patients, for instance, could relate to these deficits. Sensory dysfunction has also been linked to delusions and hallucinations as well as difficulties with attention and reading the emotions or tone of others – all of which can affect social interaction.
  • According to Dr Fellin, decreased connectivity between nerve cells (neurons) appears to play an important role in the progression of schizophrenia. So far, Dr Fellin and his group have identified which specific neurons influence sensory responses in mouse studies, but not yet in animal models of schizophrenia, with similar investigations in glial cells  - the supporting cells of the nervous system.
Javier E

The new science of death: 'There's something happening in the brain that makes no sense... - 0 views

  • Jimo Borjigin, a professor of neurology at the University of Michigan, had been troubled by the question of what happens to us when we die. She had read about the near-death experiences of certain cardiac-arrest survivors who had undergone extraordinary psychic journeys before being resuscitated. Sometimes, these people reported travelling outside of their bodies towards overwhelming sources of light where they were greeted by dead relatives. Others spoke of coming to a new understanding of their lives, or encountering beings of profound goodness
  • Borjigin didn’t believe the content of those stories was true – she didn’t think the souls of dying people actually travelled to an afterworld – but she suspected something very real was happening in those patients’ brains. In her own laboratory, she had discovered that rats undergo a dramatic storm of many neurotransmitters, including serotonin and dopamine, after their hearts stop and their brains lose oxygen. She wondered if humans’ near-death experiences might spring from a similar phenomenon, and if it was occurring even in people who couldn’t be revived
  • when she looked at the scientific literature, she found little enlightenment. “To die is such an essential part of life,” she told me recently. “But we knew almost nothing about the dying brain.” So she decided to go back and figure out what had happened inside the brains of people who died at the University of Michigan neurointensive care unit.
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  • Since the 1960s, advances in resuscitation had helped to revive thousands of people who might otherwise have died. About 10% or 20% of those people brought with them stories of near-death experiences in which they felt their souls or selves departing from their bodies
  • According to several international surveys and studies, one in 10 people claims to have had a near-death experience involving cardiac arrest, or a similar experience in circumstances where they may have come close to death. That’s roughly 800 million souls worldwide who may have dipped a toe in the afterlife.
  • In the 1970s, a small network of cardiologists, psychiatrists, medical sociologists and social psychologists in North America and Europe began investigating whether near-death experiences proved that dying is not the end of being, and that consciousness can exist independently of the brain. The field of near-death studies was born.
  • in 1975, an American medical student named Raymond Moody published a book called Life After Life.
  • Meanwhile, new technologies and techniques were helping doctors revive more and more people who, in earlier periods of history, would have almost certainly been permanently deceased.
  • “We are now at the point where we have both the tools and the means to scientifically answer the age-old question: What happens when we die?” wrote Sam Parnia, an accomplished resuscitation specialist and one of the world’s leading experts on near-death experiences, in 2006. Parnia himself was devising an international study to test whether patients could have conscious awareness even after they were found clinically dead.
  • Borjigin, together with several colleagues, took the first close look at the record of electrical activity in the brain of Patient One after she was taken off life support. What they discovered – in results reported for the first time last year – was almost entirely unexpected, and has the potential to rewrite our understanding of death.
  • “I believe what we found is only the tip of a vast iceberg,” Borjigin told me. “What’s still beneath the surface is a full account of how dying actually takes place. Because there’s something happening in there, in the brain, that makes no sense.”
  • Over the next 30 years, researchers collected thousands of case reports of people who had had near-death experiences
  • Moody was their most important spokesman; he eventually claimed to have had multiple past lives and built a “psychomanteum” in rural Alabama where people could attempt to summon the spirits of the dead by gazing into a dimly lit mirror.
  • near-death studies was already splitting into several schools of belief, whose tensions continue to this day. One influential camp was made up of spiritualists, some of them evangelical Christians, who were convinced that near-death experiences were genuine sojourns in the land of the dead and divine
  • It is no longer unheard of for people to be revived even six hours after being declared clinically dead. In 2011, Japanese doctors reported the case of a young woman who was found in a forest one morning after an overdose stopped her heart the previous night; using advanced technology to circulate blood and oxygen through her body, the doctors were able to revive her more than six hours later, and she was able to walk out of the hospital after three weeks of care
  • The second, and largest, faction of near-death researchers were the parapsychologists, those interested in phenomena that seemed to undermine the scientific orthodoxy that the mind could not exist independently of the brain. These researchers, who were by and large trained scientists following well established research methods, tended to believe that near-death experiences offered evidence that consciousness could persist after the death of the individua
  • Their aim was to find ways to test their theories of consciousness empirically, and to turn near-death studies into a legitimate scientific endeavour.
  • Finally, there emerged the smallest contingent of near-death researchers, who could be labelled the physicalists. These were scientists, many of whom studied the brain, who were committed to a strictly biological account of near-death experiences. Like dreams, the physicalists argued, near-death experiences might reveal psychological truths, but they did so through hallucinatory fictions that emerged from the workings of the body and the brain.
  • Between 1975, when Moody published Life After Life, and 1984, only 17 articles in the PubMed database of scientific publications mentioned near-death experiences. In the following decade, there were 62. In the most recent 10-year span, there were 221.
  • Today, there is a widespread sense throughout the community of near-death researchers that we are on the verge of great discoveries
  • “We really are in a crucial moment where we have to disentangle consciousness from responsiveness, and maybe question every state that we consider unconscious,”
  • “I think in 50 or 100 years time we will have discovered the entity that is consciousness,” he told me. “It will be taken for granted that it wasn’t produced by the brain, and it doesn’t die when you die.”
  • it is in large part because of a revolution in our ability to resuscitate people who have suffered cardiac arrest
  • In his book, Moody distilled the reports of 150 people who had had intense, life-altering experiences in the moments surrounding a cardiac arrest. Although the reports varied, he found that they often shared one or more common features or themes. The narrative arc of the most detailed of those reports – departing the body and travelling through a long tunnel, having an out-of-body experience, encountering spirits and a being of light, one’s whole life flashing before one’s eyes, and returning to the body from some outer limit – became so canonical that the art critic Robert Hughes could refer to it years later as “the familiar kitsch of near-death experience”.
  • Loss of oxygen to the brain and other organs generally follows within seconds or minutes, although the complete cessation of activity in the heart and brain – which is often called “flatlining” or, in the case of the latter, “brain death” – may not occur for many minutes or even hours.
  • That began to change in 1960, when the combination of mouth-to-mouth ventilation, chest compressions and external defibrillation known as cardiopulmonary resuscitation, or CPR, was formalised. Shortly thereafter, a massive campaign was launched to educate clinicians and the public on CPR’s basic techniques, and soon people were being revived in previously unthinkable, if still modest, numbers.
  • scientists learned that, even in its acute final stages, death is not a point, but a process. After cardiac arrest, blood and oxygen stop circulating through the body, cells begin to break down, and normal electrical activity in the brain gets disrupted. But the organs don’t fail irreversibly right away, and the brain doesn’t necessarily cease functioning altogether. There is often still the possibility of a return to life. In some cases, cell death can be stopped or significantly slowed, the heart can be restarted, and brain function can be restored. In other words, the process of death can be reversed.
  • In a medical setting, “clinical death” is said to occur at the moment the heart stops pumping blood, and the pulse stops. This is widely known as cardiac arrest
  • In 2019, a British woman named Audrey Schoeman who was caught in a snowstorm spent six hours in cardiac arrest before doctors brought her back to life with no evident brain damage.
  • That is a key tenet of the parapsychologists’ arguments: if there is consciousness without brain activity, then consciousness must dwell somewhere beyond the brain
  • Some of the parapsychologists speculate that it is a “non-local” force that pervades the universe, like electromagnetism. This force is received by the brain, but is not generated by it, the way a television receives a broadcast.
  • In order for this argument to hold, something else has to be true: near-death experiences have to happen during death, after the brain shuts down
  • To prove this, parapsychologists point to a number of rare but astounding cases known as “veridical” near-death experiences, in which patients seem to report details from the operating room that they might have known only if they had conscious awareness during the time that they were clinically dead.
  • At the very least, Parnia and his colleagues have written, such phenomena are “inexplicable through current neuroscientific models”. Unfortunately for the parapsychologists, however, none of the reports of post-death awareness holds up to strict scientific scrutiny. “There are many claims of this kind, but in my long decades of research into out-of-body and near-death experiences I never met any convincing evidence that this is true,”
  • In other cases, there’s not enough evidence to prove that the experiences reported by cardiac arrest survivors happened when their brains were shut down, as opposed to in the period before or after they supposedly “flatlined”. “So far, there is no sufficiently rigorous, convincing empirical evidence that people can observe their surroundings during a near-death experience,”
  • The parapsychologists tend to push back by arguing that even if each of the cases of veridical near-death experiences leaves room for scientific doubt, surely the accumulation of dozens of these reports must count for something. But that argument can be turned on its head: if there are so many genuine instances of consciousness surviving death, then why should it have so far proven impossible to catch one empirically?
  • The spiritualists and parapsychologists are right to insist that something deeply weird is happening to people when they die, but they are wrong to assume it is happening in the next life rather than this one. At least, that is the implication of what Jimo Borjigin found when she investigated the case of Patient One.
  • Given the levels of activity and connectivity in particular regions of her dying brain, Borjigin believes it’s likely that Patient One had a profound near-death experience with many of its major features: out-of-body sensations, visions of light, feelings of joy or serenity, and moral re-evaluations of one’s life. Of course,
  • “As she died, Patient One’s brain was functioning in a kind of hyperdrive,” Borjigin told me. For about two minutes after her oxygen was cut off, there was an intense synchronisation of her brain waves, a state associated with many cognitive functions, including heightened attention and memory. The synchronisation dampened for about 18 seconds, then intensified again for more than four minutes. It faded for a minute, then came back for a third time.
  • n those same periods of dying, different parts of Patient One’s brain were suddenly in close communication with each other. The most intense connections started immediately after her oxygen stopped, and lasted for nearly four minutes. There was another burst of connectivity more than five minutes and 20 seconds after she was taken off life support. In particular, areas of her brain associated with processing conscious experience – areas that are active when we move through the waking world, and when we have vivid dreams – were communicating with those involved in memory formation. So were parts of the brain associated with empathy. Even as she slipped irre
  • something that looked astonishingly like life was taking place over several minutes in Patient One’s brain.
  • Although a few earlier instances of brain waves had been reported in dying human brains, nothing as detailed and complex as what occurred in Patient One had ever been detected.
  • In the moments after Patient One was taken off oxygen, there was a surge of activity in her dying brain. Areas that had been nearly silent while she was on life support suddenly thrummed with high-frequency electrical signals called gamma waves. In particular, the parts of the brain that scientists consider a “hot zone” for consciousness became dramatically alive. In one section, the signals remained detectable for more than six minutes. In another, they were 11 to 12 times higher than they had been before Patient One’s ventilator was removed.
  • “The brain, contrary to everybody’s belief, is actually super active during cardiac arrest,” Borjigin said. Death may be far more alive than we ever thought possible.
  • “The brain is so resilient, the heart is so resilient, that it takes years of abuse to kill them,” she pointed out. “Why then, without oxygen, can a perfectly healthy person die within 30 minutes, irreversibly?”
  • Evidence is already emerging that even total brain death may someday be reversible. In 2019, scientists at Yale University harvested the brains of pigs that had been decapitated in a commercial slaughterhouse four hours earlier. Then they perfused the brains for six hours with a special cocktail of drugs and synthetic blood. Astoundingly, some of the cells in the brains began to show metabolic activity again, and some of the synapses even began firing.
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