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"Separating anatomy from what it means to be a man or a woman, New York City is moving forward with a plan to let people alter the sex on their birth certificate even if they have not had sex-change surgery. Under the rule being considered by the city's Board of Health, which is likely to be adopted soon, people born in the city would be able to change the documented sex on their birth certificates by providing affidavits from a doctor and a mental health professional laying out why their patients should be considered members of the opposite sex, and asserting that their proposed change would be permanent. Applicants would have to have changed their name and shown that they had lived in their adopted gender for at least two years, but there would be no explicit medical requirements."

"For most of its history, psychology had concerned itself with all that ails the human mind: anxiety, depression, neurosis, obsessions, paranoia, delusions. The goal of practitioners was to bring patients from a negative, ailing state to a neutral normal, or, as University of Pennsylvania psychologist Martin Seligman puts it, "from a minus five to a zero." It was Seligman who had summoned the others to Akumal that New Year's Day in 1998-his first day as president of the American Psychological Association (A.P.A.)-to share a vision of a new goal for psychology. "I realized that my profession was half-baked. It wasn't enough for us to nullify disabling conditions and get to zero. We needed to ask, What are the enabling conditions that make human beings flourish? How do we get from zero to plus five?" Every incoming A.P.A. president is asked to choose a theme for his or her yearlong term in office. Seligman was thinking big. He wanted to persuade substantial numbers in the profession to explore the region north of zero, to look at what actively made people feel fulfilled, engaged and meaningfully happy. Mental health, he reasoned, should be more than the absence of mental illness. It should be something akin to a vibrant and muscular fitness of the human mind and spirit. Over the decades, a few psychological researchers had ventured out of the dark realm of mental illness into the sunny land of the mentally hale and hearty. Some of Seligman's own research, for instance, had focused on optimism, a trait shown to be associated with good physical health, less depression and mental illness, longer life and, yes, greater happiness. Perhaps the most eager explorer of this terrain was University of Illinois psychologist Edward Diener, a.k.a. Dr. Happiness. For more than two decades, basically ever since he got tenure and could risk entering an unfashionable field, Diener had been examining what does and does not make people feel satisfied with life. Seligman's goal was

"When reports emerged 30 years ago that young gay men were suffering from rare forms of pneumonia and cancer, public health investigators scrambled to understand what appeared to be a deadly immune disorder: What were the symptoms? Who was most susceptible? What kinds of infections were markers of the disease? They were seeking the epidemiologist's most essential tool - an accurate case definition, a set of criteria that simultaneously include people with the illness and exclude those without it. With AIDS, investigators soon recognized that injection-drug users, hemophiliacs and other demographic groups were also at risk, and the case definition evolved over time to incorporate lab evidence of immune dysfunction and other refinements based on scientific advances. "If you recognize something is happening, you need a case definition so you can count it," said Andrew Moss, an emeritus professor of epidemiology at the University of California, San Francisco, and an early AIDS investigator. "You need to know whether the numbers are going up or down, or whether treatment and prevention work. And if you have a bad case definition, then it's very difficult to figure out what's going on." Once a disease can be diagnosed reliably through lab tests, creating an accurate case definition becomes easier. But when an ailment has no known cause and its symptoms are subjective - as with chronic fatigue syndrome, fibromyalgia and other diseases whose characteristics and even existence have been contested - competing case definitions are almost inevitable. Now a new study of chronic fatigue syndrome has highlighted how competing case definitions can lead to an epidemiologic "Rashomon" - what you see depends on who's doing the looking - and has stoked a fierce debate among researchers and patient advocates on both sides of the Atlantic. "

"These keep me going where other alcoholic drinks always drag me down," says Terry McAfee, a 20-something recent graduate of Pierce College in Woodland Hills, Calif. He's just plunked down $12 for four 23 ounce cans of Four Loko - the combination alcohol-caffeine drink whose manufacturer, Phusion Projects, LLC was one of four companies to receive warning letters this week from the US Food and Drug Administration. Although health-care professionals and addiction specialists have applauded the FDA, some groups agree with consumers such as Mr. McAfee that this is the latest example of a "nanny state" government pushing itself too far on the public."

"It was once a staple of public school cafeterias that blended the indulgent and the nutritious, satisfying parents and children both. But chocolate milk is uncontroversial no more. Dozens of districts have demanded reformulations. Others have banned it outright. At the center of these battles are complex public health calculations: Is it better to remove sugary chocolate flavorings at the risk that many students will skip milk altogether, missing out on crucial calcium and Vitamin D? Or should schools instead make tweaks - less fat, different sweeteners, fewer calories - that might salvage the benefits while minimizing the downside?"

"VANDALS have struck a painting that depicts South African President Jacob Zuma with his genitals hanging out. Two men defaced the picture with gobs of paint, as Mr Zuma and his African National Congress sought a court order yesterday to have the painting removed from an art gallery. The case is spiced with freedom of expression on the one hand and the right to dignity on the other. It took centre stage after the painting by Brett Murray went on display in a Johannesburg gallery this month and was reported on in local media. Mr Zuma, who has a reputation for promiscuity, took the depiction of him with his private parts exposed very personally and compared himself to a rape victim. Mr Zuma himself was put on trial for rape, and acquitted, in 2006. "The portrayal has ridiculed and caused me humiliation and indignity," Mr Zuma contended in an affidavit filed yesterday with the South Gauteng High Court in Johannesburg. Presiding over the hearing in a courtroom a few kilometres from the gallery, Judge Fayeeza Kathree-Setiloane said the full three-judge bench should hear the case because the national interest and constitutional issues are at stake. South Africa's constitution protects the right to dignity as well as to freedom of expression. She said the hearing would recommence tomorrow. Mr Zuma and the ANC sought to have the painting, titled "The Spear," removed from the Goodman Gallery and to stop the newspaper City Press from displaying a photo of it on its website. Just before the hearing was scheduled to begin, two men wielding cans of red and black paint calmly walked up to the painting hanging on a gallery wall and took turns defacing it. "Now it's completely and utterly destroyed," said Iman Rappetti, a reporter for a South African TV channel who happened to be on the scene at the time as her camera rolled. Her channel showed a man in a tweed jacket painting a red X over the president's genital area and then his face. Next, a man in a hoodie smeared bl

"Professor Philip Zimbardo conveys how our individual perspectives of time affect our work, health and well-being. Time influences who we are as a person, how we view relationships and how we act in the world."

"THE Diagnostic and Statistical Manual of Mental Disorders, published by the American Psychiatric Association, is the bible of diagnosis in psychiatry, and is used not just by doctors around the world but also by health insurers. Changing any such central document is complicated. It should therefore come as no surprise that a committee of experts charged with revising the manual has caused consternation by considering removing Asperger syndrome from the next edition, scheduled to appear in 2012. The committee argues that the syndrome should be deleted because there is no clear separation between it and its close neighbor, autism. "

"Students have always faced distractions and time-wasters. But computers and cellphones, and the constant stream of stimuli they offer, pose a profound new challenge to focusing and learning. Researchers say the lure of these technologies, while it affects adults too, is particularly powerful for young people. The risk, they say, is that developing brains can become more easily habituated than adult brains to constantly switching tasks - and less able to sustain attention. "Their brains are rewarded not for staying on task but for jumping to the next thing," said Michael Rich, an associate professor at Harvard Medical School and executive director of the Center on Media and Child Health in Boston. And the effects could linger: "The worry is we're raising a generation of kids in front of screens whose brains are going to be wired differently." But even as some parents and educators express unease about students' digital diets, they are intensifying efforts to use technology in the classroom, seeing it as a way to connect with students and give them essential skills. Across the country, schools are equipping themselves with computers, Internet access and mobile devices so they can teach on the students' technological territory. "

Like it or not - and I don't - the Obama-McConnell tax-cut deal, with its mixture of very bad stuff and sort-of-kind-of good stuff, is likely to pass Congress. Then what? The deal will, without question, give the economy a short-term boost. The prevailing view, as far as I can tell - and that includes within the Obama administration - is that this short-term boost is all we need. The deal, we're told, will jump-start the economy; it will give a fragile recovery time to strengthen. I say, block those metaphors. America's economy isn't a stalled car, nor is it an invalid who will soon return to health if he gets a bit more rest. Our problems are longer-term than either metaphor implies. And bad metaphors make for bad policy. The idea that the economic engine is going to catch or the patient rise from his sickbed any day now encourages policy makers to settle for sloppy, short-term measures when the economy really needs well-designed, sustained support.

"Witness testimony has been the gold standard of the criminal justice system, revered in courtrooms and crime dramas as the evidence that clinches a case. Yet scientists have long cautioned that the brain is not a filing cabinet, storing memories in a way that they can be pulled out, consulted and returned intact. Memory is not so much a record of the past as a rough sketch that can be modified even by the simple act of telling the story. For scientists, memory has been on trial for decades, and courts and public opinion are only now catching up with the verdict. It has come as little surprise to researchers that about 75 percent of DNA-based exonerations have come in cases where witnesses got it wrong. This month, the Supreme Court heard its first oral arguments in more than three decades that question the validity of using witness testimony, in a case involving a New Hampshire man convicted of theft, accused by a woman who saw him from a distance in the dead of night. And in August the New Jersey Supreme Court set new rules to cope with failings in witness accounts, during an appeal by a man picked from a photo lineup, and convicted of manslaughter and weapons possession in a 2003 fatal shooting. Rather than the centerpiece of prosecution, witness testimony should be viewed more like trace evidence, scientists say, with the same fragility and vulnerability to contamination. Why is a witness's account so often unreliable? Partly because the brain does not have a knack for retaining many specifics and is highly susceptible to suggestion. "Memory is weak in eyewitness situations because it's overloaded," said Barbara Tversky, a psychology professor at Columbia University's Teachers College in New York. "An event happens so fast, and when the police question you, you probably weren't concentrating on the details they're asking about." "

"Far fewer children would get a diagnosis of bipolar disorder. "Binge eating disorder" and "hypersexuality" might become part of the everyday language. And the way many mental disorders are diagnosed and treated would be sharply revised. "

Computers have become an extension of us: that is a commonplace now. But in an important way we may be becoming an extension of them, in turn. Computers are digital - that is, they turn everything into numbers; that is their way of seeing. And in the computer age we may be living through the digitization of our minds, even when they are offline: a slow-burning quantification of human affairs that promises or threatens, depending on your outlook, to crowd out other categories of the imagination, other ways of perceiving.

"Israeli scientists believe they have identified why Arabic is particularly hard to learn to read."

"About this time every year, with the fall marathon season at its zenith, racers in training begin to hear the refrain, ''You are going to ruin your knees.''"

"Babble is increasingly being understood as an essential precursor to speech, and as a key predictor of both cognitive and social emotional development. And research is teasing apart the phonetic components of babble, along with the interplay of neurologic, cognitive and social factors. "

"There's little doubt that the placebo effect's real, but it has always been argued that a person feels better because they think the pill is the real deal. But what if it works even when you know it's a fake? According to Ted Kaptchuk at Harvard Medical School and his colleagues at least one condition can be calmed by placebo, even when everyone knows it's just an inert pill. This raises a thorny question: should we start offering sugar pills for ailments without a treatment? In the latest study, Kaptchuk tested the effect of placebo versus no treatment in 80 people with irritable bowel syndrome. Twice a day, 37 people swallowed an inert pill could not be absorbed by the body. The researchers told participants that it could improve symptoms through the placebo effect. While 35 per cent of the patients who had not received any treatment reported an improvement, 59 per cent of the placebo group felt better. "The placebo was almost twice as effective as the control," says Kaptchuk. "That would be a great result if it was seen in a normal clinical trial of a drug." Edzard Ernst, professor of complementary medicine at the Peninsula Medical School in Exeter, UK, thinks that "the size of the benefit is too small to be clinically relevant". Kaptchuk agrees and wants to run some larger trials to get a better picture of the effect. If a dummy pill can improve IBS, shouldn't we be exploring its effect on other ailments? "It wouldn't work on a tumour or kill microbes, but it's likely to affect illnesses where self-appraisal is important, such as depression" says Kaptchuk. A 2008 study found that around a third of physicians had prescribed a dummy pill to unwitting patients. "Now we have shown that there are ethical ways of harnessing the placebo effect," says Kaptchuk. Surely now you can make a case for using a placebo when there are no other treatment options? Kaptchuk feels there is still an ethical dilemma here. "I'm against giving patients something unless it's been