Substance Abuse

"Nationwide percentage of treatment admissions primarily linked to alcohol has declined, while the percentage primarily linked to illicit drugs has increased"

"Data came from the National Epidemiologic Survey on Alcohol and Related Conditions Wave 2"

review of application and training practices

"review of research on economic and systemic barriers to treatment"

From a research collaboration at UW-Madison (Requires subscription or purchase)

evaluation of e-therapy program in Netherlands

From the abstract: "This chapter will review the evidence that the brain is highly plastic, exhibiting major postnatal changes, especially during adolescence, in neural circuits that appear to influence addiction susceptibility. This chapter will suggest that heritable aspects of brain structure and function that are seen developmentally may be an important endophenotypic characteristic associated with familial risk for developing alcohol dependence. Finally, a review of studies showing associations between brain structural and functional characteristics and specific genes will be offered." (requires subscription or purchase)

A supplement to the Journal of Psychoactive Drugs, focusing on improving SA treatments in California

Data from NSDUH 2004-2007

"we review experimental approaches that use various pharmacological agents to induce a stress response and subsequent craving or drug-seeking for drugs of abuse. The advantages of such an approach are that the exact same stressor can be used in different species, pharmacological stress activation works on identifiable pathways, and stress levels can be varied via dose dependent manipulations. To date, successful use of such probes in both humans and experimental animals have been achieved with noradrenergic compounds and corticotrophin-releasing hormone (CRH). Other possible approaches, such as neuroactive peptides related to central stress responses (e.g., vasopressin and substance P) and inverse benzodiazepine agonists show some promise, and we discuss recent experiments using these compounds. Future development and application of pharmacological stressors across species will be useful in assessing stress-induced craving and relapse in both human drug addiction and animal models of relapse. Through this translational approach, novel treatment interventions for addiction may be designed and tested."

"This study utilized a review of the literature together with a participatory research design to construct a conceptual model of recovery from the perspectives of addiction treatment professionals, those recovering from addictions, and researchers. "

Report of a Columbia University School of Public Health Study

"This article attempts to put modern notions of alcohol and substance abuse and dependency into a societal and cultural context with the hope of reducing the stigma of this illness while shifting the focus a bit more away from criminal solutions to those offered by health care and treatment options." (subscription or purchase for fulltext)

Description of a RAND corp study of middle school students in California

the example of buprenorphine

two separate studies reported by UWM at SFN

Experiments from Loyola University on adolescent rats causes stress hormone disruption, reported at Society for Neuroscience meeting

Discusses research from the Rosalind Franklin University and University of Illionois