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"An increase in brain inflammation, such as that caused by age, diabetes and obesity, is known to increase risk for developing Alzheimer's disease. Now scientists at UK's Southampton University are about to start a three-year study, using brain tissue generously donated by people who died with Alzheimer's disease, to see if inflammation caused by infections such as those of the urinary tract or chest, also speeds up progress of the disease." - medical news today In an announcement released on Wednesday, study leader Delphine Boche, Lecturer in Clinical Neurosciences at Southampton, says: "Many of the known risk factors for Alzheimer's, like age, obesity and diabetes, increase inflammation in the brain and we think that infections could be another risk factor." "There is already evidence that the immune system is on high alert in people with Alzheimer's and we think that an extra trigger, like an infection, could tip the balance and make immune cells switch from being protective to harmful," she adds. Alzheimer's Research UK has already put £300,000 into the project. The money is part of the charity's £20m investment in leading dementia research in the UK. The study started in January 2013, and will add to the growing pile of evidence that shows how the immune system is implicated in Alzheimer's disease. The Southampton team believes that in Alzheimer's, the immune system goes beyond its role as protector of the body and starts causing damage, like it does in an autoimmune disease. For their study, Boche and colleagues will use brain tissue generously donated by people who had Alzheimer's disease when they died. With reference to donors' medical records, the researchers will compare the brains of those who had infections when they died with those who did not. They will be particularly interested in immune cells known as "microglia", which go around mopping up cellular debris. They will use fluorescent tags to label the cells in the brain, and look

IANSNagpur (Maharashtra): Distraught over not getting compensation for losses suffered in the recent hailstorm in Maharashtra, a farmer consumed poison in the Yavatmal Collectorate office, officials said Tuesday.The incident occurred late Monday. Farmer Janardhan Raut, 70, hails from Akpuri village...

Taco Bell was well-known as one of the purveyor of junk food and they wanted to start erasing that from our memory yet they are not ready to give up the chalupa yet. Wednesday, the chain announced that it's exploring ways to offer more "balanced choices," marking just the latest sign that the fast-food industry is trying to adapt to shifting tastes and upend the conventional wisdom that it only offers caloric indulgences. Taco Bell is testing a "range of products" this year, with national launches planned for 2014. He also said existing menu items could also be reformulated but noted that the chain would remain true to its brand, CEO Greg Creed said. "We're not going to walk away from who Taco Bell is," Creed stated. Taco Bell says, by 2020, 20% of its combo meals will meet nutritional guidelines for calories and fat set out by the federal government. People eat three meals a day, as a general thought, that means a single meal would have about a third of the recommended intake of about 2,000 to 2,500 calories. The company has no idea of what portion of meals currently meet those guidelines. Taco Bell is known for urging people to eat nachos as a "fourth meal" late at night, it is a bit of a contrary to the announcement and it gained a lot of skeptics. However it demonstrates just how much difficulty the broader industry is facing to overturn its greasy-food image as people more and more look out for alternatives they believe are healthier. The lower-calorie options were a key indicator of growth at restaurant chains between 2006 and 2011 from a report by the Hudson Institute earlier this year. The increase in customer traffic rise by 11 per cent by those chains that expanded while those that didn't saw traffic fall by 15 per cent, according to the public policy research group. As customer "tastes and needs" evolve, Creed said that offering more balanced choices would be critical in helping Taco Bell reach its growth targets over the next

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