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The effect of Nineteen Eighty-Four on the English language is extensive; the concepts of Big Brother, Room 101, the Thought Police, thoughtcrime, unperson, memory hole (oblivion), doublethink (simultaneously holding and believing contradictory beliefs) and Newspeak (ideological language) have become common phrases for denoting totalitarian authority. Doublespeak and groupthink are both deliberate elaborations of doublethink, while the adjective "Orwellian" denotes "characteristic and reminiscent of George Orwell's writings" especially Nineteen Eighty-Four.

In September 2009, an album entitled The Resistance was released by English Alternative rock band Muse, which was based entirely on 1984[citation needed], including songs such as "Resistance", "Uprising" and "United States of Eurasia". The album resulted in Muse receiving a Grammy for Best Rock Album at the 53rd Grammys.

In November 2011, the United States government argued before the U.S. Supreme Court that it wants to continue utilizing GPS tracking of individuals without first seeking a warrant. In response, Justice Stephen Breyer questioned what this means for a democratic society by referencing Nineteen Eighty-Four. Justice Breyer asked, "If you win this case, then there is nothing to prevent the police or the government from monitoring 24 hours a day the public movement of every citizen of the United States. So if you win, you suddenly produce what sounds like 1984...."[65] In 1984, the book was made into a movie. In 2006, the movie V for Vendetta was released, which has many of the same running themes and principles.[66][67] In Nineteen Eighty-Four, John Hurt portrays Winston Smith, while in V for Vendetta he plays the Big Brother-like figure.[68][69]

Religion, although it is not the best method of determining moral norms, has often been very effective at promoting them. Religions often satisfy many of Daleiden's criteria for raising people to be conditioned egoists, especially by practicing the aforementioned elements of prosocial training. He suggests that this is what they are doing when they instill a sense of virtue and justice, right and wrong.

Aldous Huxley's novel Brave New World and George Orwell's 1984 imagine dystopian future societies that control the populace by advanced scientific techniques. Harris argues that moral scientists approaching truths does not imply an "Orwellian future" with "scientists at every door". Instead, Harris imagines data about normative moral issues being shared in the same way as other sciences (e.g. peer-reviewed journals on medicine).

Science of morality should identify basic components required for human flourishing, drawing heavily on findings from positive psychology. In a proto-scientific example, Abraham Maslow suggested a hierarchy of needs: basic physical survival, then social and self esteem needs, and lastly philosophical and self-actualization.

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Research looking for optimal ethical systems can draw on all the methods of science, especially those used by positive psychology. While this might include obvious methods like asking people to self-report what they think they need to flourish in life – psychology has shown that people are often surprisingly incorrect on these matters (particularly when it comes to making predictions and recollections). Some cases in point: having too many varieties of consumer goods actually creates consumer choice anxiety; when it comes to removing bandages, Dan Ariely's research suggests that "getting it over with as quickly as possible" may cause more negative memories than if one went slowly (with breaks) while being careful never to reach a 'peak' in pain; stress is not always harmful (such stress is called eustress). While very careful use of self-report can still be illuminating (e.g. bogus pipeline techniques), in the end, unconscious methods of inquiry seem to be more promising. Some unconscious methods of data collection include the Implicit Association Test and neuroimaging. In these ways, science can further our understanding of what humans need to flourish, and what ways of organizing society provide the greatest hope for flourishing.

Extensive study of cooperation has shed some light on the objective (and subjective) advantages of teamwork and empathy. The brain areas that are consistently involved when humans reason about moral issues have been investigated by a quantitative large-scale meta-analysis of the brain activity changes reported in the moral neuroscience literature.[76] In fact, the neural network underlying moral decisions overlapped with the network pertaining to representing others' intentions (i.e., theory of mind) and the network pertaining to representing others' (vicariously experienced) emotional states (i.e., empathy).

There is evidence to suggest that a risk factor for becoming victims of bullying is deficient moral development. Examples of deficient moral development may be something like neglecting an agent's intentions during an action, or blaming them for accidents. In other words, victims of bullying may be more likely to make less accurate moral assessments, for some reason. The researchers also found that, in contrast, bullies were just as morally developed as victim defenders. The difference is that bullies are more able to disengage themselves. That is, for whatever reason, bullies end up suppressing their feelings of compassion and conscience.[77]

The pilot episode depicted a plane being flown into the New York World Trade Center; it originally aired six months before 9/11. Foreshadowing a number of conspiracy theories which would arise in the wake of the September 11, 2001 attacks, the plot of the March 4, 2001 episode depicts a secret faction within the US government plotting to hijack a Boeing 727 and fly it into the World Trade Center by remote control. The stated motive was to increase the military defense budget by blaming the attack on foreign interests. In the episode, the plot is foiled by the protagonists, who board the doomed plane and deactivate the malicious autopilot system just seconds before the plane would have reached the World Trade Center.