Dr. Goodyear

IV alpha lipoic acid does decrease liver cysteine and SAMe levels.

Triple antioxidant therapy in the treatment of Hepatitis C.

Those with liver disease will have lower vitamin D levels.

Glycine shortens recovery time in alcohol induced injury.

Animal model finds glycine reduces liver damage.

Glycine found to be beneficial in liver disease.

Brain glutamic acid originates from glutamine.  Glutamine should be avoided in those with excitotoxic diseases.

gut bacterial balance plays role in progression of liver disease.  Dysbiosis worsens cirrhosis, liver failure...where as a health gut bacterial balance seems to slow progression

probiotics shown to be useful and safe in those with liver disease.

small study looked at patients with liver cirrhosis.  The authors used a low dose of IV vitamin C (5 grams) and found that this improved endothelial dysfunction.  Patients with cirrhosis were found to be low in vitamin C.  The IV vitamin C was well tolerated, despite a low dose.

statement from KU on their new study on IV vitamin C in stage III and IV ovarian cancer.

Endocrine Disrupting chemicals, xenoestrogens, alter the hormone receptors very early. Increased estrogenic load with the change in ER increase prostate cancer.

Cadmium exposure/toxicity promotes prostate tumor growth and it does this via a AR independent process.  The authors propose that it is via estrogen receptors and estrogen signaling from DHT metabolites.

Testosterone, metabolites and prostate carcinogenesis.

Study finds negligible effect of Testosterone therapy (4.8 mg) on PSA.  The study consisted of several phases, the longest being 6 years.  However, each phase the parcipitants significantly declined.  The long held belief that Testosterone and DHT promote an increase in PSA is just not supported in the science.  In fact, aromatase knockout mice don't develop prostate cancer, only BPH.

DHT at 70 mg daily shown to have no adverse effects in the prostate of "healthy" men older than 50.  However, it did increase DHT metabolites (3 alpha androstane-diol and 3 beta androstane-diol), decreased LH, Testosterone, Estradiol, FSH, increased hemoglobin, creatinine, lean mass and decreased fat.

3 subtypes of 5 alpha reductase enzymes identified in the human prostate.

low Testosterone in elderly men admitted to hospital is associated with increased mortality.

Metabolic syndrome and Low T definitely run together.  Whether one causes the other or merely associations, they reflect the risk of the other.  It is known that increasing MetS parameters drives the Testosterone lower.  In this study, they found ED, obesity, PVD, and Etoh intake associated with increased incidence of MetS.  ED and obesity are both associated with low T.

Eurycoma Longifolia, known as Tongkat Ali is a "natural" alternative method to increase Testosterone levels in those with low T.