Dr. Goodyear

Study finds 4-MEI, a known carcinogen, is found in variable levels in soft drinks.  4-MEI is found in caramel flavoring.

Animal study finds the combination of coconut oil and exercise training reduced oxidative stress and lowered blood pressure.

to be read.

To be read

to be read

Meta analysis of salivary Testosterone and cortisol finds mixed results.  The results are by no means uniform, but resistance training appears to trend to an increased salivary Testosterone and salivary Testosterone to salivary cortisol ratio.  Cardio trends the opposite.  This fits with prior literature on the types of exercise and hormone results.

Higher Testosterone and DHT levels in men was found to be positively associated with FEV1 and FVC; Estradiol was not.  The question here is cause or effect.   Also interesting is the fact that smokers had higher Testosterone levels compared to non-smokers.

low Testosterone as defined by levels < 300 was found to be associated with bone loss in aging men.

Only abstract available here.  In vitro study finds that rT3 decreased the metabolic effect of T3.  This gives the impression that rT3 has an antagonist effect to T3 on the receptor.

rat model finds T4 and rT3 receptors at plasma membrane.  T3 was found to bind with lower affinity than rT3 and T4 at the same receptor binding site.

TK-1 useful in evaluation of disease stage and therapy efficacy. TK-1 was used in conduction with LDH, CEA, NSE, and TPA.

Thymidine kinase is a good marker for DNA synthesis and proliferative activity in cancer. Healthy controls had low TK-1 levels. In contrast, advancing stage of disease was associated with increasing TK-1 levels. TK-1 also was useful in following treatment efficacy. Inflammatory GI disease was found have TK-1 levels comparable to "healthy" controls. This is important to be able to differentiate between inflammation and a useful cancer biomarker

Thymidine kinase 1 useful as a prognostic biomarker and to monitor therapy efficacy. TK-1 levels were very low in those without cancer. Higher TK-1 levels pretreatment were associated with poor prognosis and poor survival. TK-1 "increases with progress of the disease, decreases during successful therapy, and finally increases during relapse.

TK-1 to screen for cancer, as well as to follow therapy and recurrence.

Again, a study points to a "U" shaped curve in health benefits from jogging.  This study used pace, duration, and frequency and found that 2-3 x/week at slow pace provided the best health benefits compared to the moderate and strenuous runners.

5 alpha reductase inhibitor therapy reduces PSA and prostate volume.  The level of change may be used to aid in prostate cancer diagnosis.  Those with eventual diagnosis had Gleason 7 or higher.

5alpha reductase inhibitors associated with decreased risk of Gleason 2-7 prostate cancer in men with LUTS and enlarged prostate.

Alcohol in the recovery phase suppresses anabolic repair through inhibition of mTOR--even when taken with protein.

10 year f/u study of combined conjugated esterified estrogen and methyl testosterone in postmenopausal women finds no increase breast cancer risk.

Cadmium levels found to be positively associated with serum Testosterone levels in women.  Cadmium inversely associated with E2 levels.  Cadmium has been associated with increased breast cancer risk in women.