Cellular and Molecular Basis of Deiodinase-Regulated Thyroid Hormone Signaling - 0 views
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Nathan Goodyear on 10 Nov 14Anything and everything one would want to know regarding thyroid hormone signaling. Doctors, especially endocrinologists, need to read this. T4 is not or is ever inside target cells. The enzymes, deiodinase types 1, 2, and 3, are what control the thyroid hormone at the cellular levels. deiodinase-2 is what generates T3 in the cytosol of the cell. In contrast, deiodinase-3 is what generates rT3 which is inactive. High Fat diet increases deiodinase-3.