good discussion of cortisol metabolite excretion in children.

ED in type II diabetics with low Testosterone is almost a given.

Study finds that low Testosterone (43% of men) in early fractures is more of an effect of the stress associated with the event than low T itself.  The authors of this study point to additional evaluation delayed from event to provide additional support to the low T diagnosis and therapy.

24 week study of 71 women post-hysterectomy finds no increase in cardiovascular biomarkers.  Several problems with this study.  First, there was a large drop out--24%.  Second and most important, the women were pretreated with estrogen prior to Testosterone therapies were initiated.  Other studies have proposed that this protects cardiovascular risk in women on Testosterone.  Previous studies show increasing endogenous Testosterone is associated with increasing cardiovascular disease in women.   This study would be much better if no estradiol was prescribed.  That would give an unbiased view of Testosterone in post-hysterectomy women.  Not much can be taken from this study. If you doctor doesn't know this, find another doctor.  Inherent bias in this study as ties to the manufacturer of the Testosterone was disclosed. This study point to the inherent flaws in so much of the medical literature today.  Most would read the headlines and read no further, but the "further" dispels the headline as flawed.

beta glucans stimulate both innate and adaptive immune system to attack tumor cells.

Beta glucans have both an innate and adaptive effect to enhance the environment in/and around tumor.  Beta glucans stimulate the immune system signaling to attack tumors.

Beta-glucans stimulate NK cells through TH1 stimulation.  This provides the immune enhancing effect that attacks cancer cells.

Beta-glucans stimulate immune activity and thus their benefit in cancer.

Beta-glucan's effect on the immune system and cancer.

Study finds that maitake mushroom extract, MD-Fraction (a beta-glucan), has significant anti-tumor activity and anti-metastasis activity through NK activity, Antigen presenting cells, and through suppression of ICAM-1.

This was an in vitro study of Maitake mushrooms and prostate cancer.  They found that the beta-glucan stimulated apoptosis of the cancer cells.  The study also found that vitamin C potentiated this kill effect.

The D-Fraction from maitake mushrooms enhanced the cytotoxicity from NK cells through IL-12 signaling.

Calprotectin is a useful biomarker in IBD.  Colorectal cancer and GI infection can also increase fecal Calprotectin. 

fecal Calprotectin validated in the measure of IBD in children.

Calprotectin useful as a marker of intestinal inflammation.

Fecal calprotectin is found to be a much better screening test for IBD than colorectal cancer.  Though, fecal Calprotectin levels were found to be elevated in colorectal cancer compared to controls, the sensitivity and specificity was low.  In contrast, a fecal Calprotectin > 100 mg/g, in this study, was found to be specific and sensitive for IBD and excluding IBS.

Fecal Calprotectin found to be useful as monitor for Ulcerative colitis relapse.  This was found more specific for UC than Crohn's disease.  There was a 14 fold higher relapse risk in those with levels > 150.

Men with infertility associated with 2.3 fold higher risk of death. The factors evaluated were semen volume, sperm concentration, sperm motility, total sperm count, total motile sperm count.  Those that have 2 or more positive parameters were associated with increased death compared to those with normal semen analysis.

St john's wort increased insulin sensitivity and adiponectin on in vivo study.

I can only find the abstract of this article.  This article fits with the growing body of evidence that low Testosterone is a poor prognostic factor for men with prostate cancer.  This very short abstract points to using low levels of "free Testosterone" as a biomarker to treat low-risk prostate cancer.