Contents contributed and discussions participated by Nathan Goodyear - Dr. Goodyear

Reduction in the Incidence of Type 2 Diabetes With the Mediterranean Diet - 0 views

www.ncbi.nlm.nih.gov/...PMC3005482

cardiovascular disease Mediterranean diet diabetes nutrition insulin resistance inflammation

shared by Nathan Goodyear on 29 Aug 17 - No Cached

Nathan Goodyear on 29 Aug 17

Mediterranean diet + EVOO or + nuts reduced diabetes risk those in high risk by 52%. This was a 4 year f/u study. A reduction of circulating inflammatory biomarkers was also noted. Insulin resistance was noted to be improved as early as 3 months, but weight was not changed statistically throughout this study

<div class="cArrow"> </div><div class="cContentInner">Mediterranean diet + EVOO or + nuts reduced diabetes risk those in high risk by 52%. This was a 4 year f/u study. A reduction of circulating inflammatory biomarkers was also noted. Insulin resistance was noted to be improved as early as 3 months, but weight was not changed statistically throughout this study</div>

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Mediterranean diet supplemented with nuts reduces waist circumference and shifts lipopr... - 0 views

www.ncbi.nlm.nih.gov/...24075767

Mediterranean diet nuts nutrition waist circumference LDL particle number lipoproteins cardiovascular disease

shared by Nathan Goodyear on 29 Aug 17 - No Cached

Nathan Goodyear on 29 Aug 17

Mediterranean diet with added mixed nuts reduced atherogenic lipoprotein profile: decreased LDL particle number, increased LDL particle size...Even reduced waist circumference.

<div class="cArrow"> </div><div class="cContentInner">Mediterranean diet with added mixed nuts reduced atherogenic lipoprotein profile: decreased LDL particle number, increased LDL particle size...Even reduced waist circumference.</div>

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Sustaining elevated levels of nitrite in the oral cavity through consumption of nitrate... - 1 views

www.sciencedirect.com/...S1089860316301409

NO nitric oxide

shared by Nathan Goodyear on 24 Aug 17 - No Cached

Nathan Goodyear on 24 Aug 17

NO metabolism

<div class="cArrow"> </div><div class="cContentInner">NO metabolism</div>

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Dehydroascorbic acid, a blood-brain barrier transportable form of vitamin C, mediates p... - 0 views

www.ncbi.nlm.nih.gov/...PMC58796

vitamin C IV vitamin C dehydroascorbic acid brain stroke

shared by Nathan Goodyear on 22 Aug 17 - No Cached

Nathan Goodyear on 22 Aug 17

vitamin C does not cross the BBB, but its oxidize form, dehydroascorbic acid does. This experimental model looked at IV DHA. The findings was that IV DHA resulted in higher brain C levels compared to IV vitamin C.

<div class="cArrow"> </div><div class="cContentInner">vitamin C does not cross the BBB, but its oxidize form, dehydroascorbic acid does. This experimental model looked at IV DHA. The findings was that IV DHA resulted in higher brain C levels compared to IV vitamin C.</div>

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Vitamin C revisited | Critical Care | Full Text - 0 views

ccforum.biomedcentral.com/...s13054-014-0460-x

IV vitamin C vitamin C sepsis stroke oxidative stress LPS

shared by Nathan Goodyear on 22 Aug 17 - No Cached

Nathan Goodyear on 22 Aug 17

Great read on IV vitamin C in the critically ill.

<div class="cArrow"> </div><div class="cContentInner">Great read on IV vitamin C in the critically ill. </div>

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Frontiers | Prevalence of Non-responders for Glucose Control Markers after 10 Weeks of ... - 0 views

journal.frontiersin.org/...full

insulin resistance exercise HITT high intensity intermittent training

shared by Nathan Goodyear on 22 Aug 17 - No Cached

Nathan Goodyear on 22 Aug 17

Exercise is key to healthy lifestyle: High Intensity Interval Training for Insulin resistance found to improve waist circumference, systolic bp, and HOMA-IR; Increased non-responders for insulin and glucose in those with mild IR versus severe IR.

<div class="cArrow"> </div><div class="cContentInner">Exercise is key to healthy lifestyle: High Intensity Interval Training for Insulin resistance found to improve waist circumference, systolic bp, and HOMA-IR; Increased non-responders for insulin and glucose in those with mild IR versus severe IR.</div>

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The draft genome and transcriptome of Cannabis sativa | Genome Biology | Full Text - 0 views

genomebiology.biomedcentral.com/...gb-2011-12-10-r102

cannabis CBD cannabinoids cannabis sativa

shared by Nathan Goodyear on 22 Aug 17 - No Cached

Nathan Goodyear on 22 Aug 17

history of cannabis sativa

<div class="cArrow"> </div><div class="cContentInner">history of cannabis sativa</div>

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International Journal of Obesity - The pharmacology of cannabinoid receptors and their ... - 0 views

www.nature.com/...0803272a.html

CBD receptors cannabinoids

shared by Nathan Goodyear on 22 Aug 17 - No Cached

Nathan Goodyear on 22 Aug 17

CBD receptors

<div class="cArrow"> </div><div class="cContentInner">CBD receptors</div>

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Potentiation of 17β-estradiol synthesis in the brain and elongation of seizur... - 0 views

www.nature.com/...s41598-017-06630-0

DHA omega-3 omega 3 brain estrogen seizures fish oil

shared by Nathan Goodyear on 21 Aug 17 - No Cached

Nathan Goodyear on 21 Aug 17

DHA supplementation increases brain estrogen in animal study. In this study, both blunted seizure induction in the animals. This has significant implications for DHA supplementation and dietary intake of fish high in DHA for the brain through estrogen.

<div class="cArrow"> </div><div class="cContentInner">DHA supplementation increases brain estrogen in animal study. In this study, both blunted seizure induction in the animals. This has significant implications for DHA supplementation and dietary intake of fish high in DHA for the brain through estrogen. </div>

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High-dose vitamin C therapy for inclusion body myositis. - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...11411094

vitamin C IV vitamin C myositis autoimmune disease intravenous vitamin C inflammation

shared by Nathan Goodyear on 17 Aug 17 - No Cached

Nathan Goodyear on 17 Aug 17

study finds "high dose" IV vitamin C benefited 3 of 5 patients in short 4 week study. The "high dose" was not high dose at all, so that fact that a low dose of IV vitamin C will benefit dermatomysotis in over 50% of the patients in this very small study points to the question, what if actually high dose vitamin C is used.

<div class="cArrow"> </div><div class="cContentInner">study finds "high dose" IV vitamin C benefited 3 of 5 patients in short 4 week study. The "high dose" was not high dose at all, so that fact that a low dose of IV vitamin C will benefit dermatomysotis in over 50% of the patients in this very small study points to the question, what if actually high dose vitamin C is used.</div>

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Levothyroxine Monotherapy Cannot Guarantee Euthyroidism in All Athyreotic Patients - 0 views

www.ncbi.nlm.nih.gov/...PMC3148220

Thyroid hypothyroidism levothyroxine

shared by Nathan Goodyear on 16 Aug 17 - No Cached

Nathan Goodyear on 16 Aug 17

retrospective study finds that levothyroxine, T4 only therapy, is ineffective in adequately supporting peripheral T3 production in up to 20%, I would gather much higher based on my 11 years of practice.

<div class="cArrow"> </div><div class="cContentInner">retrospective study finds that levothyroxine, T4 only therapy, is ineffective in adequately supporting peripheral T3 production in up to 20%, I would gather much higher based on my 11 years of practice.</div>

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Diabetes Care - 0 views

care.diabetesjournals.org/...1777

diabetes vegan diet

shared by Nathan Goodyear on 14 Aug 17 - No Cached

Nathan Goodyear on 14 Aug 17

low fat vegan diet lowers fasting glucose levels in diabetics by 28%.

<div class="cArrow"> </div><div class="cContentInner">low fat vegan diet lowers fasting glucose levels in diabetics by 28%.</div>

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Vegetarian Diets and Blood Pressure: Meta-analysis | Cardiology | JAMA Internal Medicin... - 0 views

jamanetwork.com/...1832195

vegetarian blood pressure hypertension CVD cardiovascular disease diet

shared by Nathan Goodyear on 14 Aug 17 - No Cached

Nathan Goodyear on 14 Aug 17

vegetarian diet lowers blood pressure by 4.8 mmHg to 6.9 mmHg in meta-analysis.

<div class="cArrow"> </div><div class="cContentInner">vegetarian diet lowers blood pressure by 4.8 mmHg to 6.9 mmHg in meta-analysis.</div>

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The acute effect of high-dose intravenous vitamin C and other nutrients on blood pressu... - 0 views

www.ncbi.nlm.nih.gov/...PMC4864764

vitamin C IV vitamin C hypertension vitamin B12 blood pressure cardiovascular disease CVD

shared by Nathan Goodyear on 14 Aug 17 - No Cached

the reduction in BP within the first 10–20 min may be primarily attributed to a direct vasodilatory physiological effect, described as venodilation
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BP reduction observed after 70–90 min is likely attributable to pharmacokinetically plausible vitamin C absorption and vasodilation because of nitric oxide release
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Pharmacokinetic studies of IVC administration observed peak plasma levels within the first 90 min, with plasma levels reaching 13350 μmol/l for 50 g of IVC
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...6 more annotations...
Essential hypertension, associated with endothelial dysfunction because of an impaired nitric oxide/l-arginine pathway and impaired vasodilation can be restored by vitamin C
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marked increase in BP response when IVB12 is administered
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The mean BP increased significantly up to 12–16 mmHg systolic and diastolic independent of the dosage of vitamin B12
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The production of norepinephrine, which can stimulate angiotensin-II production, which in turn influences BP, has been suggested as a possible mechanism for the increase in BP with IVB12
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excess norephinephrine levels stimulate the sympathetic nervous system, leading to increased cortisol production, which has also been linked to increases in BP
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Animal studies have found higher serum levels of norepinephrine (noradrenaline) in the adrenal medulla of rats receiving methylcobalamin (methyl-vitamin B12)
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Nathan Goodyear on 14 Aug 17

IV vitamin C in mostly normotensive patients (> 30 grams) reduced blood pressure. Some of the patients were pre-hypertensive. Vitamin B12 increase the blood pressure.

<div class="cArrow"> </div><div class="cContentInner">IV vitamin C in mostly normotensive patients (> 30 grams) reduced blood pressure. Some of the patients were pre-hypertensive. Vitamin B12 increase the blood pressure.</div>

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Nutrients | Free Full-Text | Vitamin C, Aging and Alzheimer's Disease | HTML - 0 views

www.mdpi.com/...htm

vitamin C alzheimer Alzheimer's disease inflammation inflamm-aging

shared by Nathan Goodyear on 13 Aug 17 - No Cached

Nathan Goodyear on 13 Aug 17

vitamin C

<div class="cArrow"> </div><div class="cContentInner">vitamin C</div>

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Cannabidiol inhibits paclitaxel-induced neuropathic pain through 5-HT1A receptors witho... - 0 views

www.ncbi.nlm.nih.gov/...PMC3969077

CBD hemp oil cannabinoids chemotherapy cancer pain neuropathy Paclitaxel

shared by Nathan Goodyear on 11 Aug 17 - No Cached

Nathan Goodyear on 11 Aug 17

Animal study finds that CBD reduces chemotherapy induced neuropathy and pain.

<div class="cArrow"> </div><div class="cContentInner">Animal study finds that CBD reduces chemotherapy induced neuropathy and pain.</div>

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Mechanisms of cannabidiol neuroprotection in hypoxic-ischemic newborn pigs: Role of 5HT... - 0 views

www.sciencedirect.com/...S0028390813001238

CBD cannabinoids hemp oil brain excitotoxicity inflammation oxidative stress

shared by Nathan Goodyear on 11 Aug 17 - No Cached

Nathan Goodyear on 11 Aug 17

Another animal study finds CBD is neuroprotective. This study actually found that CBD reduced excitotoxicity, inflammation, and oxidative stress.

<div class="cArrow"> </div><div class="cContentInner">Another animal study finds CBD is neuroprotective. This study actually found that CBD reduced excitotoxicity, inflammation, and oxidative stress.</div>

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Cannabidiol, neuroprotection and neuropsychiatric disorders - ScienceDirect - 0 views

www.sciencedirect.com/...S1043661816000396

CBD cannabinoids hemp oil brain neuroplasticity

shared by Nathan Goodyear on 11 Aug 17 - No Cached

Nathan Goodyear on 11 Aug 17

CBD is neuroprotective, neuroplastic, and neurogenic. CBD reduces oxidative stresses well.

<div class="cArrow"> </div><div class="cContentInner">CBD is neuroprotective, neuroplastic, and neurogenic. CBD reduces oxidative stresses well.</div>

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Cannabidiol reduces neuroinflammation and promotes neuroplasticity and functional recov... - 0 views

www.sciencedirect.com/...S0278584616302524

brain cod cannabinoids hemp oil BDNF neuroplasticity TBI brain injury

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Nathan Goodyear on 11 Aug 17

CBD increases BDNF--neuroplasticity.

<div class="cArrow"> </div><div class="cContentInner">CBD increases BDNF--neuroplasticity.</div>

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Optimizing natural fertility: a committee opinion - Fertility and Sterility - 0 views

www.fertstert.org/...fulltext

fertility infertility Mercury Hg lifestyle intervention smoking alcohol caffeine

shared by Nathan Goodyear on 11 Aug 17 - No Cached

Nathan Goodyear on 11 Aug 17

Good review on the process of "natural" fertility; no drugs involved.

<div class="cArrow"> </div><div class="cContentInner">Good review on the process of "natural" fertility; no drugs involved.</div>

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