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Nathan Goodyear

Increased estrogen formation and estrogen to androgen ratio in the synovial fluid of pa... - 0 views

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    high estrogen to Testosterone levels in synovial fluid in those with RA.  The authors here propose that DHEA can stimulate inflammation through aromatase activity.
Nathan Goodyear

Sex hormones in male patients with systemic lupus erythematosus: a comparison with othe... - 0 views

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    low Testosterone found in men with Lupus; the authors conclude is is more associative with chronic disease.
Nathan Goodyear

http://onlinelibrary.wiley.com/store/10.1002/art.11105/asset/11105_ftp.pdf;jsessionid=4... - 0 views

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    good review of sex hormones and LUPUS; whether it is causative or not, sex hormones trends exist in LUPUS i.e. low DHEA in both sexes, low progesterone in women, and low Testosterone in women>men.
Nathan Goodyear

Waist-to-height ratio as a predictor of serum testosterone in ageing men with symptoms ... - 0 views

  • WHt ratio was calculated by dividing waist (cm) by height (cm)
  • nverse relationships of BMI and WC with TT and cFT have been previously documented in unselected cohorts of adult men
  • over the age of 54 years
  • ...5 more annotations...
  • adjusting WC for height (WHt ratio) improves the prediction of TT and cFT compared with either BMI or WC alone
  • there were inverse correlations between cFT, TT and either BMI or WC
  • for each unit increase in BMI, there was a 2% fall in TT and cFT
  • for each 10 cm increment in WC, TT and cFT levels declined by 7%.
  • The magnitude of this relationship between increasing BMI and decreasing TT is similar to that described in the Massachusetts Male Ageing Study
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    waist to height ratio reliable predictor of low T in men.
Nathan Goodyear

Effects of Resveratrol on Polycystic Ovary Syndrome: A Double-blind, Randomized, Placeb... - 0 views

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    Only abstract available.  Resveratrol found to reduce total Testosterone by 23% and DHEAS by 22% in women with PCOS;  a decrease in insulin by 32% and improved insulin sensitivity was also noted.
Nathan Goodyear

Anabolic and androgenic activities of Bulbine natalensis stem in male Wistar rats: Phar... - 0 views

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    Bulbine natalensis Baker stem found to increase Testosterone by up to 350% in animal studies in 2 weeks.  The dose with the optimum response was 25 and 50 mg/kg, with the most best effect at 50 mg/kg.  LH and FSH production was increase but exact mechanism not discussed.  Only abstract available here.
Nathan Goodyear

Reproductive toxicologic evaluations of Bulbine natalensis Baker stem extract in albino... - 0 views

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    Bulbine natalensis Baker stem extract found to increase LH and Testosterone in wistar rats in 7 days at doses of 25 to 50 mg/kg; this effect was not found at 100 mg/kg.  The result was an increase in testes size, rate of mating, libido, and fertility.
Nathan Goodyear

Serum sex hormone and plasma homocysteine levels in middle-aged and elderly men - 0 views

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    no correlation between Testosterone, estradiol, and DHEAS levels and homocysteine in men >40.
Nathan Goodyear

http://jap.physiology.org/content/jap/82/1/49.full.pdf - 0 views

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    To much protein intake can be a bad thing.  This study found that high protein intake and high protein/carbohydrate intake lowered basal Testosterone levels.
Nathan Goodyear

Effects of weight loss on leptin, sex hormones, and measures of adiposity in obese chil... - 0 views

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    weight loss decreases leptin in boys and the result is an increase in Testosterone
Nathan Goodyear

Effect of low-fat diet on female sex hormone levels. - PubMed - NCBI - 0 views

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    low fat diet drops estrogen levels precipitously in women.  It also dropped Testosterone levels.
Nathan Goodyear

Dihydrotestosterone: a rati... [Baillieres Clin Endocrinol Metab. 1998] - PubMed - NCBI - 0 views

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    DHT as a Testosterone alternative
Nathan Goodyear

Apple - Start - 0 views

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    salivary testosterone positively associated with violent crimes in this small study.
Nathan Goodyear

Estradiol and Metabolic Syndrome in Older Italian Men: The InCHIANTI Study -- Maggio et... - 0 views

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    Estradiol found to be associated with Metabolic syndrome in men. This was independent of other confounding variables.  Most men, the excess estradiol comes from increased aromatase activity on testosterone.
Nathan Goodyear

Matrix metalloproteinases in the pathogenesis of estradiol-induced nonbacterial prostat... - 0 views

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    In rat model, Estradiol shown to increase inflammation in lateral lobes of the prostate.  Androgens, Testosterone > DHT, shown to inhibit this inflammatory response.  
Nathan Goodyear

Full Text: Editorial - 0 views

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    high aromatase activity and conversion of testosterone to estrogen conversion plays a role in lupus and RA.  Inflammatory cytokines are shown to increase aromatase activity.
Nathan Goodyear

Sex hormones influence on the immune system: basic and clinical aspects in autoimmunity - 0 views

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    high conversion of testosterone to estrogen conversion in men is from increased aromatase activity.  Inflammatory cytokines, such as IL-6, TNF-alpha, has been shown to increase aromatase activity and at the same time increase IL-6 and other inflammatory cytokines is the result of increased aromatase activity.
Nathan Goodyear

Oestrogen and benign prostatic hyperplasia: effects on stromal cell proliferation and l... - 0 views

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    this study finds aromatase presence in the stroma of the prostate and not the epithelium of the prostate.  This would support the thought that increased aromatase activity and thus conversion of Testosterone to Estradiol in the prostate stroma contributes to BPH.
Nathan Goodyear

TBioMed | Full text | The Estradiol-Dihydrotestosterone model of prostate cancer - 0 views

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    Estradiol in men inhibits apoptosis.  Testosterone promotes apoptosis.   Thus the decreasing T:E2 ratio in men as they age is an important step in the development of prostate cancer.
Nathan Goodyear

Immunohistochemical evidence of the existence and localization of aromatase in human pr... - 0 views

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    aromatase activity is present in the prostate.  The conversion of Testosterone to Estradiol via aromatase activity has been shown to contribute to inflammation and prostate enlargement.
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