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Nathan Goodyear

Association Between Viral Hepatitis and Erectile Dysfunction: A Population-Based Case-C... - 0 views

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    Low Testosterone, low libido, and ED associated with prior hepatitis B and hepatitis C.  
Nathan Goodyear

Acute effects of interferon-alpha administration on testosterone concentrations in heal... - 0 views

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    Interferon therapy in men with hepatitis C was found to decrease total Testosterone and Free Androgen index at the level of the gonads; this was independent of the HPA in this study.
Nathan Goodyear

Chronic hepatitis C infection and sex hormone levels: effect of disease severity and re... - 0 views

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    hepatitis associated with a decline in total Testosterone.  This was a positive correlation with worsening hepatitis.  Free Testosterone was not effected.  Interesting, SHBG increased.
Nathan Goodyear

Sexual dysfunction in males with chronic hepatitis C and antiviral therapy: interferon-... - 0 views

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    Study of men with hepatitis C and interferon therapy found decrease in free and total Testosterone levels in men.  The study results suggest a non-HPA effect, which suggests more of a peripheral effect at the level of the TEsticles.
Nathan Goodyear

Testosterone-induced muscle hypertrophy is associated with an increase in satellite cel... - 0 views

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    Testosterone increases muscle satellite cells in men.
Nathan Goodyear

Gonadotropin treatment restores in vitro interleukin-1β and tumour necrosis f... - 0 views

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    Inverse relationship between Testosterone and LPS, IL-1beta, and TNF-alpha.
Nathan Goodyear

Is serum sex hormone-binding globulin a dominant risk factor for metabolic syndrome? - ... - 0 views

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    Nice study of Chinese men, only abstract available, finds that serum total Testosterone and SHBG were inversely associated with metabolic syndrome in men.  SHBG association was the strongest and TT the weakest.  Free Testosterone had no association in this study.
Nathan Goodyear

Fundamental Aspects of Hypogonadism in the Aging Male - 0 views

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    good discussion of low T effect on a man's metabolism: particularly muscle mass.
Nathan Goodyear

Interrelationships of serum testosterone and free testosterone index with FFM and stren... - 0 views

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    Free Testosterone is better indicator of muscle strength than total Testosterone--in this case, free Testosterone index.
Nathan Goodyear

Relationship between low free testosterone levels and loss of muscle mass. - PubMed - NCBI - 0 views

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    low free Testosterone associated with muscle loss in men compared to no association with total Testosterone in Japanese men.
Nathan Goodyear

Testosterone reference ranges in normally cycling healthy premenopausal women. - PubMed... - 0 views

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    To be read
Nathan Goodyear

Estradiol, but not testosterone, heightens cortisol-mediated negative feedback on pulsa... - 0 views

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    INteresting.  Estradiol enhances cortisol negative feedback on ACTH production in both men and women.
Nathan Goodyear

Direct Inhibitory Effect of Glucocorticoids upon Testicular Luteinizing Hormone Recepto... - 0 views

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    glucocorticoids inhibit Testosterone production via down regulation of LH receptors at the level of the testicles.
Nathan Goodyear

Acute Suppression of Circulating Testosterone Levels by Cortisol in Men: The Journal of... - 0 views

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    Cortisol inhibits Testosterone production in men.
Nathan Goodyear

https://www.auanet.org/common/pdf/education/clinical-guidance/Testosterone-Deficiency-W... - 0 views

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    2013 AUA white paper on low Testosterone.
Nathan Goodyear

In Older Men an Optimal Plasma Testosterone Is Associated With Reduced All-Cause Mortal... - 0 views

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    men with Testosterone levels in the middle quintiles had the lowest risk of death compared to low and high quintile levels.  
Nathan Goodyear

Serum Androgen Concentrations in Young Men: A Longitudinal Analysis of Associations wit... - 0 views

  • this study provides strong evidence that the decline in serum testosterone and the increase in SHBG concentrations begins during the 3rd decade of life
  • Increasing age was independently associated with increasing SHBG
  • There was no significant difference in the testosterone level between black and white men after the adjustment for age
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    to be fully read
Nathan Goodyear

Serum testosterone levels in healthy young black and white men. - PubMed - NCBI - 0 views

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    Black men found to have higher Total Testosterone and higher free Testosterone compared to caucasian men. 
Nathan Goodyear

Total testosterone may not decline with ageing in Korean men aged 40 years or older. - ... - 0 views

  • Longitudinal change of TT was approximately + 0·8% per year.
  • TT was negatively correlated with body mass index (BMI), waist circumference and glucose
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    In study of 220 Korean mean, there was only a small decline in total Testosterone in men followed from 2002 to 2011.  The change amounted to 0.8% annually.  The level was 18.1 nmol to 17.8 nmol.  TT was inversely associated with BMI, waist and glucose.
Nathan Goodyear

The effect of testosterone replacement on endogenous inflammatory cytokines and lipid p... - 0 views

  • testosterone induced reductions in TNFalpha (-3.1 +/- 8.3 vs. 1.3 +/- 5.2 pg/ml; P = 0.01) and IL-1beta (-0.14 +/- 0.32 vs. 0.18 +/- 0.55 pg/ml; P = 0.08) and an increase in IL-10 (0.33 +/- 1.8 vs. -1.1 +/- 3.0 pg/ml; P = 0.01); the reductions of TNFalpha and IL-1beta were positively correlated
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    Testosterone reduced TNF-alpha and IL-1 beta in men.
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