JAMA Network | Archives of Internal Medicine | Combined Estrogen and Testosterone Use a... - 0 views
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Nathan Goodyear on 16 May 12this study revealed increased breast cancer risk in women on "estrogen" and "testosterone" therapy. Now, several problems here: first, are these synthetic hormone or bioidentical. Second, the dosages appear, in what is written, to be supra physiologic. Third, giving supra physiologic estradiol and testosterone will obviously create imbalances and growth potential. Fourth, how were the women evaluated prior to starting hormone therapy and then were they remonitered (unlikely), fifth, were hormone metabolites evaluated (too, also unlikely). This study has serious flaws and very little can be extrapolated other than: don't take supra physiologic hormone levels without appropriate evaluation. Enough said