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Nathan Goodyear

Oestrogens and prostate cancer - 0 views

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    Study confirms aromatase activity in the prostate itself. Systemic Testosterone and Estradiol evaluation (ie blood) will not necessarily reflect endogenous prostate aromatase activity.
Nathan Goodyear

Aromatase and prostate cancer. [Minerva Endocrinol. 2006] - PubMed - NCBI - 0 views

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    Aromatase activity and resultant Testosterone to estrogen production plays role in prostate disease development.
Nathan Goodyear

Obesity, Androgens, Estrogens, and Cancer risk - 0 views

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    good discussion of the relationship between obesity, hormones and cancer. This article also contrasts the difference between men and women.
Nathan Goodyear

Essential Role for Estrogen Receptor β in Stromal-Epithelial Regulation of Pr... - 0 views

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    ER beta agonists shown to be anti-proliferative in the prostate and "ablated preexisting prostatic epithelial hyperplasia".  This has important implications: low T conditions increase ER alpha expression, which increases ER alpha production.  Low T is a pro inflammatory state in men, which increases aromatase activity.  Thus increase conversion of T to E2 in the stroma of the prostate results in growth.  ER beta is not activated.
Nathan Goodyear

Aromatase activity and interleukin-6... [J Clin Endocrinol Metab. 1995] - PubMed - NCBI - 0 views

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    Inflammatory cytokine, IL-6, shown to increase aromatase activity in breast cancer.
Nathan Goodyear

Stimulation of aromatase activity in bre... [Mol Cell Endocrinol. 1994] - PubMed - NCBI - 0 views

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    inflammatory cytokine, TNF-alpha, increases aromatase activity.  This article discusses the increased production of estrone from androstenedione from aromatase activity in fat tissue in the breast.
Nathan Goodyear

Full Text: Editorial - 0 views

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    high aromatase activity and conversion of testosterone to estrogen conversion plays a role in lupus and RA.  Inflammatory cytokines are shown to increase aromatase activity.
Nathan Goodyear

Increased Endogenous Estrogen Synthesis Leads to the Sequential Induction of Prostatic ... - 0 views

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    study shows that over expression of aromatase activity and resultant increased estradiol/estrone production increases prostatitis and plays a role in prostate cancer.  
Nathan Goodyear

International Journal of Impotence Research - Treatment of testosterone-induced gynecom... - 0 views

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    arimidex, also known as anastrozole, is shown to be an effective aromatase inhibitor in men.  These case studies used arimidex to successfully stimulate testosterone production by limiting testosterone to estrogen production.  This was found to be useful in the treatment of gynecomastia.
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