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Nathan Goodyear

Exercise-induced right ventricular dysfunction and structural remodelling in endurance ... - 0 views

eurheartj.oxfordjournals.org/...998

endurance athletes training heart health injury

shared by Nathan Goodyear on 09 Jan 15 - No Cached
  • In a cohort of well-trained athletes, we demonstrated that intense endurance exercise causes an acute reduction in RV function that increases with race duration and correlates with increases in biomarkers of myocardial injury
  • no relationship between LV function and biomarker levels
  • focal gadolinium enhancement and increased RV remodelling were more prevalent in those athletes with a longer history of competitive sport, suggesting that repetitive ultra-endurance exercise may lead to more extensive RV change and possible myocardial fibrosis
  • ...22 more annotations...
  • he cardiac impact of both acute and cumulative exercise is greatest on the RV.
  • Greater reductions in RV function occurred in those athletes competing for a longer duration, suggesting that the heart has a finite capacity to maintain the increased work demands of exercise
  • cardiac injury is greatest in the least trained
  • Previous investigators have documented reductions in RV function in less trained subjects over the marathon distance
  • We enrolled elite and subelite athletes and found a significant association between fitness (VO2max) and the reduction in post-race RVEF
  • Even after many years of detraining, cardiac dilation may not completely regress in elite athletes
  • The focus on well-trained athletes may be of particular relevance, given that they perform exercise of highest intensity and duration most frequently, and, thus, may be at a greater risk of cumulative injury.
  • The lack of correlation between increases in troponin and changes in LV function seen in this study has been previously interpreted as evidence that post-exercise elevations in cardiac biomarkers are benign.
  • a significant correlation between changes in RVEF and post-race biomarker levels and this relationship was even stronger in the athletes who completed the race of longest duration, the ultra-triathlon
  • The correlations with RVEF, but not LVEF, provide further evidence of the differential effects of intense exercise on RV and LV function
  • BNP release during intense exercise is associated with greater relative increases in RV systolic pressures, but not LV pressures
  • BNP may provide a measure of both acute RV load and the resultant fatigue which occurs when this load is sustained
  • It has been demonstrated that ventricular load increases with exercise intensity and is greater for the RV than the LV,29 thus potentially explaining why the RV is more susceptible to fatigue after prolonged exercise.
  • This study demonstrates, for the first time, an association between endurance exercise of increasing duration and structural, functional, and biochemical markers of cardiac dysfunction in highly trained athletes
  • Functional abnormalities were confined to the RV and were largely reversible 1 week following the event
  • there remained a significant minority of athletes in whom there was evidence of myocardial fibrosis in the interventricular septum
  • RV abnormalities may be acquired through cumulative bouts of intense exercise and provides direction for prospective investigations aimed at elucidating whether extreme exercise may promote arrhythmias in some athletes.
  • the acute injury and chronic remodelling of the myocardium both disproportionately affect the RV and it remains possible that the two are linked.
  • focal DGE was confined to the interventricular septum and commonly at the site of RV attachment
  • emerging evidence that intense endurance exercise may be associated with an excess in arrhythmic disorders, the mechanisms for which remain unexplained
  • RVEF (and not LVEF) was reduced in athletes with complex ventricular arrhythmias when compared with healthy athletes and non-athletes without arrhythmias
  • it is premature to conclude that these changes may represent a proarrhythmic substrate
  • Nathan Goodyear on 09 Jan 15
     
    Study finds endurance racing results in reduce Right ventricle ejection fraction even in elite athletes.  This post-race RVEF reduction is associated with VO2max.
Nathan Goodyear

Effects of Acute Exposure to M... [Res Sports Med. 2014 July-September] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...24950112

resistance training exercise cortisol GH Testosterone sports

shared by Nathan Goodyear on 23 Jun 14 - No Cached
  • Nathan Goodyear on 23 Jun 14
     
    Article looked at the anabolic effect of low-intensity resistance exercise.  This study found a decrease in cortisol post-exercise, but no increase in anabolic effects: GH and total Testosterone.  The exercise was in untrained men, which could explain some of the decrease in the anabolic effect with the men in this study.
Nathan Goodyear

Thieme E-Journals - International Journal of Sports Medicine / Abstract - 0 views

www.thieme-connect.de/...DOI

exercise training sports sports medicine resistance training weight lifting

shared by Nathan Goodyear on 30 Nov 17 - No Cached
  • Nathan Goodyear on 30 Nov 17
     
    Only abstract available here: compound resistance treaining in highly trained young men found to increase GH and Testosterone over isolation exercises. Those that trained > 2 years had significnt increase in Testosterone pre/post exercise compared to no statistical change in those traing < 2 years.
Nathan Goodyear

Protein Ingestion Prior To Sleep Improv... [Med Sci Sports Exerc. 2012] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...22330017

whey protein exercise post-exercise recovery support muscle sports

shared by Nathan Goodyear on 13 Apr 12 - No Cached
  • Nathan Goodyear on 13 Apr 12
     
    protein intake post exercise improves recovery. In this study, they had young men take in 20 gm of protein prior to bed after resistance training at 8 pm.
Nathan Goodyear

Effects of supplement timing and resistance exerci... [Med Sci Sports Exerc. 2006] - Pu... - 0 views

www.ncbi.nlm.nih.gov/...17095924

exercise protein creatine glucose amino acids sports athletics

shared by Nathan Goodyear on 15 Aug 11 - No Cached
  • Nathan Goodyear on 15 Aug 11
     
    pre/post exercise supplementation important in maintaining muscle function and promoting muscle growth
Nathan Goodyear

Intravenous Fluid Use in Athletes - 0 views

www.ncbi.nlm.nih.gov/...PMC3435915

IV nutrition intravenous fluids exercise sports medicine sports athlete athletes

shared by Nathan Goodyear on 13 Jan 15 - No Cached
  • The current data suggest that IV rehydration is faster than oral
  • There may be physiological benefits of decreased heart rate and norepinephrine in athletes rehydrated via IV route
  • Muscle damage during exercise in the heat was assessed by myoglobin and creatine kinase
  • ...4 more annotations...
  • Postexercise blood 1 hour and 24 hours showed no differences in circulating myoglobin or creatine kinase
  • IV administration of fluids can rapidly replace plasma volume
  • The rapid increase in plasma volume is transient, and no measureable difference between IV and oral prehydration exists after 15 minutes of exercise
  • The use of IV fluid may be beneficial for a subset of fluid sensitive athletes
  • Nathan Goodyear on 13 Jan 15
     
    IV nutrition pre-event, intra-event, and post-event for recovery.
Nathan Goodyear

Neuroimaging of sport concussion: persistent alterations in brain structure and functio... - 0 views

www.nature.com/...s41598-017-07742-3

post concussion syndrome concussion TBI head injury brain exercise sports sports medicine sports injury

shared by Nathan Goodyear on 19 Sep 17 - No Cached
  • Nathan Goodyear on 19 Sep 17
     
    New study suggest brain healing lags far behind in concussion recovery.
Nathan Goodyear

Salivary and plasma cortisol and testosterone r... [J Sports Sci. 2013] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...24279436

cortisol Testosterone saliva salivary hormone hormones serum exercise training sports

shared by Nathan Goodyear on 02 Dec 13 - No Cached
  • Nathan Goodyear on 02 Dec 13
     
    Plasma and salivary cortisol and Testosterone levels correlated in small study that looked at post-training hormones changes in athletes.  Cortisol and Testosterone peaked in all experimental groups. 
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