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Nathan Goodyear

Salivary estradiol and testosterone in filipin... [Am J Hum Biol. 2014] - PubMed - NCBI - 0 views

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    Study finds association between elevated Estradiol in young men and obesity.  No correlation was found with Testosterone.  This fits other research that points to early increased Estradiol production and late decrease in low T.  The men in this study were "young".  Testing was done in saliva.
Nathan Goodyear

Persistent intraprostatic androgen c... [J Clin Endocrinol Metab. 2006] - PubMed - NCBI - 0 views

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    Serum evaluation of hormones is useless from a functional perspective.  This study finds that post-castration, despite a 94% decline in serum androgens, intraprostatic androgens stay much higher.
Nathan Goodyear

Tissue and serum levels of principal androgens in benign prostatic hyperplasia and pros... - 0 views

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    Serum evaluation of Testosterone and DHT poorly correlates with intraprostatic hormone levels.  Must look to saliva to get better clinical picture.
Nathan Goodyear

Plasma and salivary steroid hormone resp... [J Strength Cond Res. 2011] - PubMed - NCBI - 0 views

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    plasma and salivary cortisol and Testosterone correlate in study of study assessing overreaching.
Nathan Goodyear

Salivary and plasma cortisol and testosterone r... [J Sports Sci. 2013] - PubMed - NCBI - 0 views

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    Plasma and salivary cortisol and Testosterone levels correlated in small study that looked at post-training hormones changes in athletes.  Cortisol and Testosterone peaked in all experimental groups. 
Nathan Goodyear

https://dl-web.dropbox.com/get/Public/Research/Salivary%20testosterone.pdf?w=AAA0jQi7Hq... - 0 views

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    salivary testosterone shown to be reliable measure of testosterone in men with suspected low T.
Nathan Goodyear

Diagnostic significance of salivary testosterone measurement revisited: using liquid ch... - 0 views

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    salivary testosterone, as measured by LC-MS and ELISA, showed strong correlation with serum free "calculated" testosterone.
Nathan Goodyear

Longitudinal Study of Hormonal and P... [J Clin Endocrinol Metab. 2013] - PubMed - NCBI - 1 views

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    salivary and urine testing used to assess sex hormone levels in young twins.  
Nathan Goodyear

Psychoendocrine and physical performan... [Aggress Behav. 2008 Nov-Dec] - PubMed - NCBI - 0 views

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    Rugby training resulted in a decrease in T:C salivary ratio through a decline in resting testosterone level.  In contrast, competition events increased the T:C ratio primarily through an increase in Cortisol production.
Nathan Goodyear

Simultaneous determination of salivary testosterone and dehydroepiandrosterone using LC... - 0 views

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    salivary testosterone and DHEA using LC-MS/MS accuracy exceeds 98.5%.  Compare that with historical 50% resolution of pain with a hysterectomy.  There is no perfect test, but if accuracy exceeds 98%, you have  reliable test.
Nathan Goodyear

Comparison of salivary versus serum testos... [Menopause. 2009 Jul-Aug] - PubMed - NCBI - 0 views

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    this study looked at salivary testosterone to serum testosterone and found poor correlation.  One major problem with this study is the significantly smaller amount (10 fold) of testosterone in women than men in healthy individuals.  This study took place in postmenopausal women, which would have significantly lower levels than healthy women.  They also don't discuss the pitfalls of equilibrium dialysis of serum free testosterone.  Another major flaw is the mere logic of looking at serum for tissue activity.   What is the correlation between serum levels and tissue activity.  There is tremendous assumptions being undertaken that serum levels of testosterone whether total or free translate to genomic or non-genomic signaling.  I also wonder if newer techniques using Mass Spec can better detect the typically pico levels of testosterone in women's saliva?  This study does nothing to dissuade the use of salivary testing.
Nathan Goodyear

Diagnostic significance of free salivary testosterone measurement using a direct lumine... - 0 views

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    salivary testosterone found to correlate will with blood free testosterone in men.
Nathan Goodyear

[Serum and salivary testosterone levels in erectil... [Orv Hetil. 1998] - PubMed - NCBI - 0 views

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    Small study looking at testosterone in men with ED.  They found "serum total testosterone level is not a sensitivity indicator for detection of hypogonadism".  Salivary free testosterone levels is the best way to evaluate androgen levels.
Nathan Goodyear

Further evidence for the usefulness of the salivary... [Horm Res. 1986] - PubMed - NCBI - 0 views

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    salivary testosterone found to be reliable in men and women during testosterone therapy.  The salivary testosterone levels correlated with serum.
Nathan Goodyear

Salivary testosterone diurnal variation and psychopathology in adolescent males and fem... - 0 views

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    low testosterone in boys associated with anxiety/depression and attention problems.  Disruptive behavior found in girls with low testosterone.  All determined by salivary testing.
Nathan Goodyear

ScienceDirect.com - Hormones and Behavior - Salivary Testosterone Determination in Stud... - 0 views

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    High correlation of salivary and serum testosterone in children.  
Nathan Goodyear

Saliva as a matrix for measuring free androgens: comparison with serum androgens in pol... - 0 views

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    early study looking at saliva testing in infertility treatment.  This goes back almost 33 years.  But of course, it took medicine 176 years to recommend that Vitamin C help prevent scurvy on long sea journeys.
Nathan Goodyear

Salivary Sex Hormone Measurement in a National, Population-Based Study of Older Adults - 0 views

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    Another study supports saliva hormone testing.  This study involved 2,722 individuals and tested estradiol, progesterone, DHEA and testosterone in men and women.  All of these are sex hormones.  Someone needs to tell the insurance companies that the overwhelming evidence supports saliva hormone testing.  But, that would mean they are even interested in the science.
Nathan Goodyear

Seasonality, waist-to-hip ratio, an... [Psychoneuroendocrinology. 2006] - PubMed - NCBI - 0 views

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    another article discusses the seasonal variation of testosterone.  Again, testosterone levels are shown to be highest in the fall months and lowest during the summer months.  This has been found to be the case in both sexes.
Nathan Goodyear

Rapid determination of natural steroidal hormones in saliva for the clinical diagnoses - 0 views

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    recent study proves the scientific validity of sex hormone evaluation via saliva.  Most labs today use ELIZA.  The new future will be mass spectroscopy.
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