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Nathan Goodyear

Obesity and age as dominant correlates of low testosterone in men irrespective of diabe... - 0 views

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    Testosterone was inversely associated with weight and age.  This study points to this as the primary driver of low T, even in Diabetics.  Total Testosterone was inversely associated with BMI and free (calculated) Testosterone was associated with age.
Nathan Goodyear

The effects of testosterone tr... [Int J Obes Relat Metab Disord. 1992] - PubMed - NCBI - 0 views

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    Testosterone shown to benefit middle aged, obese men.
Nathan Goodyear

Reduction in the incidence of type 2 diabetes w... [N Engl J Med. 2002] - PubMed - NCBI - 0 views

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    Lifestyle interventions significantly reduced weight and incidence of type II Diabetes compared to metformin.  Both significantly reduced the incidence, but lifestyle interventions were more beneficial than metformin.
Nathan Goodyear

Benefits of Modest Weight Loss in Improving Cardiovascular Risk Factors in Overweight a... - 0 views

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    Weight loss of just 5% reduced cardiovascular disease risk.  Lifestyle interventions are still some of the best treatment options available for many chronic diseases of aging. 
Nathan Goodyear

JCI - Chronic inflammation in fat plays a crucial role in the development of obesity-re... - 0 views

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    how inflammation contributes to obesity.  Nice discussion of the inflammatory signaling that leads to obesity.  This occurs predominately in white adipose tissue WAT.  This leads to insulin resistance and type II DM.
Nathan Goodyear

Obesity, Diabetes, and Gut Microbiota - 0 views

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    the gut microbiota can alter energy  homeostasis, resulting in obesity and diabetes
Nathan Goodyear

International Journal of Impotence Research - Abstract of article: Epidemiology: testos... - 0 views

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    low Testosterone shown to be associated with insulin resistance, poor glucose control, elevated HgbA1c, and obesity
Nathan Goodyear

Selective increases of bifidobacteria in gut microflora improve high-fat-diet-induced d... - 0 views

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    decreased bifidobacterium gut flora results in increased absorption of LPS in high fat diets resulting in endotoxemia. This plays a significant role in diabetes
Nathan Goodyear

JCI - Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the me... - 0 views

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    great read on the relationship of adiponectin and insulin resistance, metabolic syndrome, diabetes,  and obesity.
Nathan Goodyear

Changes in inflammatory biomarkers acros... [J Gastrointest Surg. 2009] - PubMed - NCBI - 0 views

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    obesity leads to inflammatory marker elevations and associated inflammatory disease states.

    These results come from the NHANES 1999-2004.
Nathan Goodyear

Vitamin D deficiency and insulin ... [J Pediatr Endocrinol Metab. 2011] - PubMed - NCBI - 0 views

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    vitamin D associated with low adiponectin, obesity and insulin resistance in african Americans
Nathan Goodyear

Low Testosterone Levels Are Common and Associated with Insulin Resistance in Men with D... - 0 views

  • Low testosterone levels were independently associated with insulin resistance in men with type 1 diabetes as well as type 2 diabetes
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    low Testosterone associated with insulin resistance
Nathan Goodyear

The Incretins: GLP-1 Agonists and DPP-4 Inhibitors | Diabetesnet.com - 0 views

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    GLP-1 agonists improve insulin/glucose control
Nathan Goodyear

Pharmacokinetics, pharmacodynamics, and safety of exenatide in patients with type 2 dia... - 0 views

  • exenatide dose-dependently reduced postprandial plasma glucose excursion by insulinotropism
  • suppression of plasma glucagon, and slowing of gastric emptying.
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    exenatide improves insulin/glucose regulation
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