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Nathan Goodyear

Testosterone replacement therapy improves insulin resistance, glycaemic control, viscer... - 0 views

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    3 months of IM Testosterone found to improve glycemic control, improved insulin sensitivity, improved cholesterol, and aided weight loss in men with low T and type II diabetes.
Nathan Goodyear

Involvement of gut microbiota in the developmen... [Gut Microbes. 2012] - PubMed - NCBI - 0 views

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    gut microbiota, and the imbalance of (dysbiosis) contributes to LPS and inflammation.  This results in obesity and type II DM.
Nathan Goodyear

JCI - Chronic inflammation in fat plays a crucial role in the development of obesity-re... - 0 views

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    how inflammation contributes to obesity.  Nice discussion of the inflammatory signaling that leads to obesity.  This occurs predominately in white adipose tissue WAT.  This leads to insulin resistance and type II DM.
Nathan Goodyear

Hypoadiponectinemia in Obesity and Type 2 Diabetes: Close Association with Insulin Resi... - 0 views

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    obesity and type II diabetes found to be associated with low adiponectin and elevated insulin as found in insulin resistance.  This study revealed the inverse relationship of adiponectin and insulin resistance.  The interesting thing is that inflammation causes insulin resistance.  Here you can see the inflammation-insulin resistance-low adiponectin-obesity-diabetes link.
Nathan Goodyear

Interaction Between Obesity and the Gut Microbiota: Relevance in Nutrition - 0 views

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    Gut inflammation resultant from dysbiosis leads to inflammation, obesity, insulin resistance, type II DM, hypertension...
Nathan Goodyear

International Journal of Impotence Research - Abstract of article: Epidemiology: testos... - 0 views

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    low Testosterone shown to be associated with insulin resistance, poor glucose control, elevated HgbA1c, and obesity
Nathan Goodyear

ingentaconnect Adipose Tissue Macrophages, Low Grade Inflammation and Insulin Re... - 0 views

  • “M1” or “classically activated” macrophages
  • PPAR-gamma agonists
  • “M2” or an “alternatively activated” anti-inflammatory phenotype
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    ATMs and obesity induced inflammation initiates insulin resistance and thus type II diabetes. The bodies reaction to a fat cell is no different than a bacterial, viral, or parasitic infection.  The body recognizes something (fat) that shouldn't be there and it attempts to destroy it and remove it.
Nathan Goodyear

Fatty acid-induced mitochondrial uncoupling in ... [Diabetologia. 2007] - PubMed - NCBI - 0 views

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    how increase FFA uncouples mitochondria.  Role in development of insulin resistance and type II diabetes
Nathan Goodyear

Metabolic Effects of Fructose and the Worldwide Increase in Obesity - 0 views

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    high fructose intake results in insulin resistance, obesity, type II DM, and high blood pressure
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