Group items tagged

Filter: All | Bookmarks | Topics Simple Middle

Targeting gut microbiota in obesity: effects of prebiotics and probiotics : Article : N... - 0 views

www.nature.com/...nrendo.2011.126.html

LPS lipopolysaccharides gut microbiota dysbiosis inflammation obesity metabolic endotoxemia health probiotics

shared by Nathan Goodyear on 18 Jan 12 - No Cached

gut microbes have a role in the host's metabolic homeostasis
...

Cancel
lipopolysaccharide (LPS)
...

Cancel
Associations between circulating LPS level, consumption of a high-fat diet and the presence of obesity and type 2 diabetes mellitus have been confirmed in humans
...

Cancel
...8 more annotations...
associations have been proposed between high-fat diet, metabolic endotoxemia and levels of inflammatory markers (TLRs and SOCS3) in mononuclear cells
...

Cancel
A link between energy intake (high-fat diet) and metabolic endotoxemia has also been described
...

Cancel
high-fat diet induces metabolic endotoxemia in healthy individuals.
...

Cancel
metabolic endotoxemia is associated with systemic and adipose tissue inflammation in pregnant women with obesity
...

Cancel
A growing amount of evidence indicates that changes in the integrity of the intestinal barrier occur both in the proximal and the distal part of the gut, which can contribute to the entrance of LPS into the systemic circulation
...

Cancel
intestinal endocannabinoid system
...

Cancel
The low-grade systemic inflammation that characterizes the obese phenotype is controlled by peptides that are produced in the gut. These peptides are influenced by the presence or absence of the gut microbiota
...

Cancel
these findings suggest that the gut microbiota modulates the biological systems that regulate the availability of nutrients, energy storage, fat mass development and inflammation in the host, which are all components of the obese phenotype
...

Cancel

Nathan Goodyear on 18 Jan 12

good look of how the the gut health, or lack there of, can influence energy homeostasis and contribute to obesity. This article points to the presence of LPS playing a role in metabolic endotoxemia. It does discuss the importance of the microbiota and their possible role in the low-grade systemic inflammation condition that is obesity.

<div class="cArrow"> </div><div class="cContentInner">good look of how the the gut health, or lack there of, can influence energy homeostasis and contribute to obesity. This article points to the presence of LPS playing a role in metabolic endotoxemia. It does discuss the importance of the microbiota and their possible role in the low-grade systemic inflammation condition that is obesity.</div>

...

Cancel

Gut Microbiota in Health and Disease | Physiological Reviews - 0 views

physrev.physiology.org/...859

gut microbiota dysbiosis health GALT immune system LPS diet nutrition disease metabolic endotoxemia inflammation

shared by Nathan Goodyear on 27 Jul 14 - No Cached

Nathan Goodyear on 27 Jul 14

Must read and a great read at that, of the GI's contribution to health or disease. The article reviews the current understanding of the GALT layer and it's contribution to health or metabolic endotoxemia and how this then leads to disease. The article reviews the effects of disrupted GI bacteria in the gut as well as in other organ systems.

<div class="cArrow"> </div><div class="cContentInner">Must read and a great read at that, of the GI's contribution to health or disease. The article reviews the current understanding of the GALT layer and it's contribution to health or metabolic endotoxemia and how this then leads to disease. The article reviews the effects of disrupted GI bacteria in the gut as well as in other organ systems.</div>

...

Cancel