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Nathan Goodyear

Diagnostic Characteristics of Late-Night Salivary Cortisol Using Liquid Chromatography-... - 0 views

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    night-time cortisol via LC shown to reliable in detection of Cushing Syndrome
Nathan Goodyear

Large-Core Breast Biopsy: Abnormal Salivary Cortisol Profiles Associated with Uncertain... - 0 views

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    salivary cortisol testing used to assess stress associated with breast biopsy
Nathan Goodyear

Depression and cortisol responses to psychological stress: A meta-analysis - 0 views

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    Depression found to have higher cortisol levels compared to non-depressed men and women.
Nathan Goodyear

Social support and oxytocin interact to suppress cortisol and subjective responses to p... - 0 views

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    Oxytocin shown to suppress cortisol release in response to psychosocial stressors.  The question is where does this modulation occur.
Nathan Goodyear

Neuropsychopharmacology - Testosterone Suppression of CRH-Stimulated Cortisol in Men - 0 views

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    Testosterone inhibits CRH and thus cortisol.
Nathan Goodyear

Out-Patient Screening for Cushing's Syndrome: The Sensitivity of the Combination of Cir... - 0 views

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    salivary cortisol recommended for evaluating Cushing's syndrom
Nathan Goodyear

Kent Holtorf: Long Term Weight Loss - More Than Will Power? - 0 views

  • which is a major reason for the regaining of lost weight with dieting as well being the mechanism behind stress induced weight gain (it is not due to increased cortisol).
  • f greater than 10, it demonstrates there is a degree of leptin resistance contributing to an inability to lose weight
  • that it is difficult to lose weight with leptin resistance. High carbohydrate diets and in particular high-fructose corn syrup is shown to significantly increase leptin resistance and is a likely mechanism that high fructose corn syrup is associated with obesity
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  • inactive thyroid hormone called thyroxine
  • it is problem inside the cell that the inactive T4 is not converted to T3 but rather to a mirror image of T3 called reverse T3. The reverse T3 has the opposite effect of T3, blocking the effects of T3 and lowering rather than increasing metabolism.
  • Studies are showing that stress and dieting (especially yo-yo dieting) can set this hormone into action as well as chronic illness such as diabetes, chronic fatigue syndrome and fibromyalgia.
  • As soon as the body senses a reduction in calories, the production of reverse T3 is stimulated to lower metabolism
  • With chronic dieting or stress, the body often stays in this "starvation mode" with elevated levels of reverse T3 and decreased levels of T3, which is a major reason for the regaining of lost weight with dieting as well being the mechanism behind stress induced weight gain (it is not due to increased cortisol).
  • which is a major reason for the regaining of lost weight with dieting as well being the mechanism behind stress induced weight gain (it is not due to increased cortisol).
  • which is a major reason for the regaining of lost weight with dieting as well being the mechanism behind stress induced weight gain (it is not due to increased cortisol).
  • Studies are showing that such standard testing will miss 80% of thyroid dysfunction
  • ree T3/reverse T3 ratio
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    Fantastic review by Dr. Holtorf on reverse T3, leptin, and weight loss
Nathan Goodyear

Using testosterone and cortisol as bioma... [J Strength Cond Res. 2014] - PubMed - NCBI - 0 views

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    Study followed Total Testosterone:Cortisol ratios to monitor catabolic/anabolic states in basketball players.  The authors followed serum levels and monitored them 24-36 hours post game.  Those playing > 25 min/game had the lowest TT:C and highest cortisol indicating a catabolic state and making recovery critical.
Nathan Goodyear

Estradiol, but not testosterone, heightens cortisol-mediated negative feedback on pulsa... - 0 views

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    INteresting.  Estradiol enhances cortisol negative feedback on ACTH production in both men and women.
Nathan Goodyear

Acute Suppression of Circulating Testosterone Levels by Cortisol in Men: The Journal of... - 0 views

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    Cortisol inhibits Testosterone production in men.
Nathan Goodyear

An inverse relationship between cortisol and BDNF levels in schizophrenia: data from hu... - 0 views

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    Elevated Cortisol found to have inverse association with BDNF.
Nathan Goodyear

Serum sex hormone-binding globulin and cortisol concentrations are associated with over... - 0 views

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    Over training syndrome and its effects on cortisol, SHBG, and IGF-1; or as they authors call it overreaching.  The study contrasted OR versus basic training.
Nathan Goodyear

Association of Psoriasis Severity with Serum Prolactin, Thyroid Hormones, and Cortisol... - 0 views

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    study suggests that PrL, T3 and cortisol may impact psoriasis treatment in positive manner.
Nathan Goodyear

Gender and sex hormones in multiple sclerosis pathology and therapy - 0 views

  • It is now well recognized that the disease manifestation is reduced in pregnant women with relapsing-remitting MS
  • This occurs particularly during the third trimester when levels of estrogens (estradiol and estriol) and progesterone (see Table 2) are elevated up to about 20 times
  • This seems well correlated with a decrease in active white matter lesions detected by MRI
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  • This clinical improvement is however followed by temporary rebound exacerbations at post-partum, when the hormone levels decline
  • a shift from Th1 to Th2 immune response, expansion of suppressive regulatory T lymphocytes and decrease in the number of circulating CD16+ natural killer (NK)-cells
  • Th1 lymphocytes secrete proinflammatory cytokines (e.g. IL-2, IFNgamma, lymphotoxin) while Th2 cells secrete anti-inflammatory cytokines (e.g. IL-4, IL-5, IL-10), which favor humoral-mediated responses
  • Th2 cytokines are associated with down-regulation of Th1 cytokines and this Th2 shift is believed to provide protection from allograft rejection during pregnancy as well as from Th1-mediated autoimmune disease
  • it is worth noting that the levels of other hormones with anti-inflammatory activity (1,25-dihydroxy-vitamin D3, norepinephrine, cortisol) also increase by 2 to 4 times during late pregnancy
  • 1,25-dihydroxy vitamin D3 induces regulatory T-cell function important for development of self-tolerance
  • breast-feeding does not alter the relapse rate in women with MS
  • Leptin is a pleiotropic hormone produced primarily by adipocytes but also by T lymphocytes and neurons
  • Several lines of evidence indicate that leptin contributes to EAE/MS pathogenesis, influencing its onset and clinical severity, by acting as a proinflammatory cytokine which promotes regulatory T cell (Treg) anergy and hyporesponsiveness, resulting in increased Th1 (TNFalpha, INFgamma) and reduced Th2 (IL-4) cytokine production
  • circulating leptin levels are increased in relapsing-remitting MS patients (men and women analyzed together) while the CD4+CD25+Treg population decreases
  • As the leptin plasma concentrations are proportional to the amount of fat tissue, obese/overweight individuals produce higher levels of leptin
  • Nielsen et al found that estradiol and progesterone exert neuroprotection against glutamate neurotoxicity, while MPA antagonizes the neuroprotective effect of estradiol and exacerbated neuron death induced by glutamate excitotoxicity
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    very good review of the differences in MS and hormones between the sexes.
Nathan Goodyear

An update: salivary hormones and physical exercise - Gatti - 2010 - Scandinavian Journa... - 0 views

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    salivary cortisol, testosterone, DHEA testing is a "real alternative" to serum testing in the scrutiny of athletes.
Nathan Goodyear

The acute hormonal response to free weig... [J Strength Cond Res. 2013] - PubMed - NCBI - 0 views

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    This study found that free weights induced a greater increase in Testosterone, GH, and cortisol, than machine.  This study only looked at serum levels.
Nathan Goodyear

Plasma and salivary steroid hormone resp... [J Strength Cond Res. 2011] - PubMed - NCBI - 0 views

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    plasma and salivary cortisol and Testosterone correlate in study of study assessing overreaching.
Nathan Goodyear

Effects of heavy-resistance training on hormonal response patterns in younger vs. older... - 0 views

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    resistance training associated with an increase in Total Testosterone and free Testosterone in young men with exercise and rest.  In contrast, with older men, the increase was seen with TT only.  An increase in IGF-1 was seen and a decrease in resting cortisol was seen.
Nathan Goodyear

Hormones.gr - 0 views

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    Nice review of the impact of exercise on cortisol and catecholeamines.
Nathan Goodyear

Influence of dietary carbohydrate intake on the free testosterone: cortisol ratio respo... - 0 views

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    excessive carb restriction in athletes can lower Testosterone levels and negatively impact Testosterone to cortisol ratio. This will limit performance and hinder recovery.
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