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Nathan Goodyear

SALIVARY CORTISOL ASSAYS FOR ASSESSING PITUITARY-ADRENAL RESERVE - PETERS - 2008 - Clin... - 0 views

  • Since salivary cortisol concentrations were shown to reflect the free, biologically active fraction in plasma, salivary assay may, in selected cases, provide results of greater diagnostic significance than plasma total concentrations.
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    salivary cortisol found to be superior to total serum cortisol levels.
Nathan Goodyear

Salivary cortisol in psychoneuroend... [Psychoneuroendocrinology. 1994] - PubMed - NCBI - 0 views

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    saliva cortisol accurately reflects the free, serum cortisol.
Nathan Goodyear

Utility of Salivary Cortisol Measurements in Cushing's Syndrome and Adrenal Insufficiency - 1 views

  • It is expected that the use of the measurement of salivary cortisol will become routine in the evaluation of patients with disorders of the HPA axis.
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    Salivary cortisol testing shown to have sensitivity and specificity that exceeds 90%.  Final Quote: "salivary cortisol will become routine in the evaluation of patients with disorders of the HPA axis
Nathan Goodyear

Salivary cortisol in psychoneuroendocrine research... [Psychoneuroendocrinology. 1994] ... - 0 views

  • The assessment of cortisol in saliva has proven a valid and reliable reflection of the respective unbound hormone in blood. To date, assessment of cortisol in saliva is a widely accepted and frequently employed method in psychoneuroendocrinology
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    saliva cortisol testing "widely" accepted in 1984
Nathan Goodyear

Biology of post-traumatic stress disorder ... [J Neuroendocrinol. 2008] - PubMed - NCBI - 0 views

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    appears that PTSD results in divergent catecholamine and cortisol levels as patients age.  The catecholamines (norepinephrine) will elevate and the cortisol will progressive decrease.  Additionally, this is revealed in salivary cortisol testing
Nathan Goodyear

Effect of Tongkat Ali on stress hormones and psychological mood state in moderately str... - 0 views

  • At the age of 60, testosterone levels are typically only 40-50% of youthful levels and may be lower
  • Eurycoma contains a group of small peptides referred to as “eurypeptides” that are known to have effects in improving energy status and sex drive in studies of rodents
  • The effects of tongkat ali in restoring normal testosterone levels appears to be less due to actually “stimulating” testosterone synthesis, but rather by increasing the release rate of “free” testosterone from its binding hormone, sex-hormone-binding-globulin (SHBG)
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  • The current study found that daily supplementation with tongkat ali root extract (200 mg/day) improves stress hormone profile (lower cortisol; higher testosterone) and certain mood state parameters (lower tension, anger, and confusion)
  • tongkat ali supplementation (100 mg/day) improved lean body mass, 1-RM strength, and arm circumference to a significantly greater degree compared to a placebo group.
  • In a recent 12-week trial [46] of Eurycoma longifolia supplementation (300 mg/day), men (30–55 years of age) showed significant improved compared to placebo in the Physical Functioning domain of the SF-36 quality of life survey
  • sexual libido was increased by 11%
  • In men with low testosterone levels (average age 51 years), one month of daily supplementation with tongkat ali extract (200 mg/day) resulted in a significant improvement in serum testosterone levels and quality-of-life parameters
  • rise in cortisol and drop in testosterone is an early signal of “overtraining”
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    Tongkat Ali, commonly known as long jack, is found to reduce stress and increase Testosterone.  Stress is one of the common causes of low T in men.  It appears that long Jack functions as an adaptogen.
Nathan Goodyear

Blood Hormones as Markers of Training Stress and Overtraining | SpringerLink - 0 views

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    Older article, but good one still on hormones and overtraining.  Look to the Testosterone/Cortisol ratio.  OTS will lead to decreased Testosterone and increased cortisol resulting in chronic catabolic state.
Nathan Goodyear

The role of salivary cortisol measured by liquid chromatography-tandem mass spectrometr... - 0 views

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    LC-MS/MS shown to be useful in evaluation in people with suspected elevated cortisol levels.  In this study, they found the dexamethasone suppression test was required.  The point however is that cortisol is a valid medium and this was with LC-MS/MS instead of the more commonly used ELIZA technique.
Nathan Goodyear

Changes in cortisol and testostero... [J Sports Med Phys Fitness. 2000] - PubMed - NCBI - 0 views

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    long endurance competitive events associated with catabolic hormone balances found in a low T:C ratio.  This occurs primarily through an elevation in cortisol and small drop in Testosterone.  The recovery phase is anabolic through a rise in T:C, primarily through a return to baseline by cortisol and an increase in Testosterone.
Nathan Goodyear

Use of saliva for monitoring unbound free cor... [Clin Chim Acta. 1981] - PubMed - NCBI - 0 views

  • measurement of saliva cortisol can be used sufficiently to monitor unbound free concentrations in serum.
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    this study showed that salivary cortisol can be used to monitor the active free, unbound form of cortisol
Nathan Goodyear

A prospective study of diurnal cortisol and cognitive function in community-dwelling el... - 0 views

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    High salivary cortisol and decrease metabolism of cortisol (urinary) is associated with increased cognitive decline in the elderly.
Nathan Goodyear

Diurnal Cortisol Dysregulation, Functional Disability, and Depression in Women With Ova... - 0 views

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    with with ovarian cancer, found to have dysregulated cortisol patterns.  Found to be associated with increased rates of depression. Oh, by the way, this study utilized salivary cortisol.
Nathan Goodyear

Diagnosis of secondary adrenal insufficiency in patients with hypothalamic-pituitary di... - 1 views

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    salivary cortisol testing said to be "first-line" and preferable to serum cortisol evaluation
Nathan Goodyear

ScienceDirect - Clinical Biochemistry : Advantage of salivary cortisol measurements in ... - 1 views

  • nighttime salivary cortisol is more adequate than serum in the screening of Cushing's syndrome
  • Morning salivary cortisol is as good as serum as screening test for patients with Addison's disease
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    salivary cortisol is shown to be reliable for both Addison's and Cushing's Syndrome
Nathan Goodyear

Social Support and Salivary Cortisol in Women With Metastatic Breast Cancer - 0 views

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    better cortisol pattern seen in women with good social support.  This is indicative of a better balanced HPA axis and thus immune system balance.  Significant implications in women with metastatic breast cancer.  Cortisol evaluated by saliva
Nathan Goodyear

Vagal Regulation, Cortisol, and Sleep Disruption in Women with Metastatic Breast Cancer - 0 views

  • an association between disrupted nocturnal sleep and flattened diurnal cortisol rhythm in women with metastatic breast cancer
  • They suggest that the stress-buffering effects of sleep may be associated with improved parasympathetic tone and normalized cortisol patterns during the day.
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    women with metastatic breast cancer shown to have more disruption in cortisol pattern and thus dysfunctional sleep.  This has implications on survival.
Nathan Goodyear

STRESS, DIURNAL CORTISOL AND BREAST CANCER SURVIVAL | eCampus CancerPEN - 0 views

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    Stanford University looked at stress, diurnal cortisol pattern and breast cancer survival using...you guessed it, salivary cortisol
Nathan Goodyear

Emerald | Policing: An International Journal of Police Strategies & Management | Post-t... - 0 views

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    elevated cortisol levels found in moderate/severe PTSD in police officers.  Again, saliva testing was used for cortisol evaluation.
Nathan Goodyear

Ecological salivary cortisol ana... [J Am Psychiatr Nurses Assoc. 2008] - PubMed - NCBI - 0 views

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    salivary cortisol testing validated and shown to be useful in evaluating cortisol levels.
Nathan Goodyear

Ecological salivary cortisol spe... [J Am Psychiatr Nurses Assoc. 2008] - PubMed - NCBI - 0 views

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    The use of salivary cortisol testing is shown to provide multivariate analysis of cortisol levels.
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