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Nathan Goodyear

Program Planner | Presentation - 0 views

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    Just an abstract from the Presentation at the 2014 Scientific Session. The abstract points to a 40% reduction in CAD with the onset of BHRT (Estradiol and progesterone topical) within 6 years of menopause compared to women 10 years post-menopause.  This points to timing as a critical component of BHRT in women and CAD.
Nathan Goodyear

Transdermal progesterone cream for vasomotor ... [Obstet Gynecol. 1999] - PubMed - NCBI - 0 views

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    Transdermal BHRT in the form of Progesterone found to reduce hot flashes by 83%.
Nathan Goodyear

A randomized, controlled trial comparing the efficacy and safety of aqueous subcutaneou... - 0 views

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    Bioidentical progesterone used in IVF.  This is not new, the SQ administration is.  So, physicians cry against BHRT, yet bioidentical progesterone has been used for years in the treatment of infertility.
Nathan Goodyear

Early repeated administration of progesterone improves the recovery of neuropathic pain... - 0 views

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    Very interesting article.  Early Progesterone treatment, in animal model, shown to improve neuropathic pain recovery.  This is by no means the first study to show this.  This has been shown numerous times in TBI, but the timing of therapy was the purpose of this article.  What is very interesting here is that the metabolites implicated here in the recovery are the same metabolites implicated in an increased tumor potential.
Nathan Goodyear

Systemic lupus erythematosus and hormone repla... [Menopause Int. 2007] - PubMed - NCBI - 0 views

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    Women with SLE enter menopause earlier.  This study comments on the need for hormone testing in women with SLE and appropriate therapy as indicated.  This study recommended against estrogen therapy due to studies revealing increased flares.  The problem with those studies is that they looked at OCPs and synthetic HRT.
Nathan Goodyear

Medroxyprogesterone interferes with ovarian steroid ... [Nat Med. 1997] - PubMed - NCBI - 0 views

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    head to head study in rhesus monkeys finds that medroxyprogesterone acetate negates the positive vascular effects of estradiol.  This is in contrast to the bioidentical progesterone.
Nathan Goodyear

Topical progesterone cream does not increase thrombotic and inflammatory factors in pos... - 0 views

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    Transdermal progesterone improves menopausal symptoms without an change in inflammatory markers.
Nathan Goodyear

Anti-inflammatory effect of proteoglyca - PubMed Mobile - 0 views

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    progesterone inhibits LPS stimulated inflammation.  Progesterone actually inhibits TLR4 activation.  The statement that progesterone has no place in hormone therapy is both uneducated and uninformed.
Nathan Goodyear

Improved outcomes from the administration of proge... [Crit Care. 2008] - PubMed - NCBI - 0 views

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    progesterone shown to be neuroprotective in individuals with traumatic brain injuries.  In addition to improved neurologic function, there was a decreased mortality rate in the progesterone treated group compared to placebo.
Nathan Goodyear

Progesterone for acute traumatic ... [Cochrane Database Syst Rev. 2011] - PubMed - NCBI - 0 views

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    significant improvement found in 3 studies that looked at progesterone in people with acute traumatic brain injuries. 
Nathan Goodyear

Emory WHSC :: Press Releases - 0 views

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    progesterone shown to have promise as a treatment in those with traumatic brain injury
Nathan Goodyear

Seasonality of reproductive function and weight loss in rural Nepali women - 0 views

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    weight loss shown to have hormone component.  Decreasing progesterone associated with weight gain.  Saliva progesterone used to follow women in this study.
Nathan Goodyear

Saliva Hormone Testing - 3 views

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     Dr. Lee eloquently explains the physiology behind saliva testing and progesterone
Nathan Goodyear

Development and validation of stable-isotope dilution liquid chromatography-tandem mass... - 0 views

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    LC-ESI-MS/MS) for hormone evaluation has been validated for hormone testing.  Progesterone was used in this study.
Nathan Goodyear

ScienceDirect - Pathologie Biologie : Saliva assays in clinical and research biology - 0 views

  • the saliva concentration reflects the free blood concentration.
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    saliva testing of stress and sex hormones have been utilized since the early 1980's and described as "well validated" in the literature.
Nathan Goodyear

Progesterone inhibits growth and induces apoptosis... [Ann Clin Lab Sci. 1998 Nov-Dec] ... - 0 views

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    Progesterone inhibits breast cancer growth and triggers cell death in breast cancer cells
Nathan Goodyear

Pregnancy, progesterone and progestins in relation... [J Steroid Biochem Mol Biol. 2005... - 0 views

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    Bioidentical Progesterone does not increase breast cancer risk
Nathan Goodyear

[The in vivo effect of the local administration of... [J Gynecol Obstet Biol Reprod (Pa... - 0 views

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    progesterone decreases cell growth activity in human breast cells exposed to Estradiol
Nathan Goodyear

Estradiol and progesterone regulate the proliferat... [Fertil Steril. 1998] - PubMed re... - 0 views

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    Again, progesterone reduces Estradiol stimulated breast cell growth
Nathan Goodyear

Influences of percutaneous administration of estra... [Fertil Steril. 1995] - PubMed re... - 0 views

  • Increased P concentration significantly decreases the number of cycling epithelial cells.

  • CONCLUSION: Exposure to P for 10 to 13 days reduces E2-induced proliferation of normal breast epithelial cells in vivo.

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    Progesterone reduces Estradiol breast cell growth
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