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Nathan Goodyear

Glutamate and the glutamate receptor system: a tar... [Int J Geriatr Psychiatry. 2003] ... - 0 views

  • Under certain conditions, glutamate has a toxic action resulting from an activation of specific glutamate receptors, which leads to acute or chronic death of nerve cells.
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    deep, heavy read on glutamate excitotoxicity and neuronal death leading to neurodegenerative disease
Nathan Goodyear

SpringerLink - NeuroMolecular Medicine, Volume 10, Number 4 - 0 views

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    nice discussion of mitochondria and their implication in aging and neurodegenerative disease
Nathan Goodyear

Mitochondria: a therapeutic target in neurodegener... [Biochim Biophys Acta. 2010] - Pu... - 0 views

  • mitochondrial dysfunction has a central role in the pathogenesis of Alzheimer's, Parkinson's and Huntington's diseases and amyotrophic lateral sclerosis
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    mitochondrial dysfunction has a central role in the pathogenesis of Alzheimer's, Parkinson's and Huntington's diseases and amyotrophic lateral sclerosis
Nathan Goodyear

Oxidative stress and neurotoxicity. [Chem Res Toxicol. 2008] - PubMed result - 0 views

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    Great article on how oxidative stress, and thus mitochondrial dysfunction, are at the core of neurodegenerative diseases
Nathan Goodyear

Mitochondrial DNA damage and repair in neurodegene... [DNA Repair (Amst). 2008] - PubMe... - 0 views

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    mitochondria dysfunction at core of aging and neurodegenerative disease
Nathan Goodyear

Mitochondria, metabolic disturbances, oxidative st... [J Neurol Sci. 2007] - PubMed result - 0 views

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    Great article on CoQ10, mitochondrial function, the kynurenine system and neurodegenerative diseases
Nathan Goodyear

Coenzyme Q10 effects in neurodegenerative disease. [Neuropsychiatr Dis Treat. 2009] - P... - 0 views

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    CoQ10 shown to be beneficial in treatment of neurodegenerative diseases, Parkinson's, Alzheimer's, ALS, Huntington's, in animal models
Nathan Goodyear

Coenzyme Q treatment of neurodegenerative diseases... [Mitochondrion. 2007] - PubMed re... - 0 views

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    CoQ10 shows promise in neurodegenerative disorders
Nathan Goodyear

Mitochondrial dynamics in cell death and neurodege... [Cell Mol Life Sci. 2010] - PubMe... - 0 views

  • abnormal mitochondrial dynamics relevant to neuronal synaptic loss and cell death in neurodege
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    Mitochondrial dynamics in cell death and neurodegeneration.
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