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Nathan Goodyear

Salivary estradiol and testosterone in filipin... [Am J Hum Biol. 2014] - PubMed - NCBI - 0 views

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    Study finds association between elevated Estradiol in young men and obesity.  No correlation was found with Testosterone.  This fits other research that points to early increased Estradiol production and late decrease in low T.  The men in this study were "young".  Testing was done in saliva.
Nathan Goodyear

ROUND-UP: Predicting depression in boys (PNAS*) - an expert responds - AusSMC - Austral... - 0 views

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    Elevated salivary am cortisol predicts increased risk of depression in boys.  
Nathan Goodyear

Journal of Endocrinological Investigation - 0 views

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    Birth control pills increase resting cortisol levels.  This study looked at salivary and urinary cortisol.
Nathan Goodyear

Self-Reported Depressive Symptoms and Stress Levels in Healthy Young Men: Associations ... - 0 views

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    Elevated morning cortisol associated with depression in men. This study looked at saliva for assessment of free cortisol.
Nathan Goodyear

Persistent intraprostatic androgen c... [J Clin Endocrinol Metab. 2006] - PubMed - NCBI - 0 views

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    Serum evaluation of hormones is useless from a functional perspective.  This study finds that post-castration, despite a 94% decline in serum androgens, intraprostatic androgens stay much higher.
Nathan Goodyear

Tissue and serum levels of principal androgens in benign prostatic hyperplasia and pros... - 0 views

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    Serum evaluation of Testosterone and DHT poorly correlates with intraprostatic hormone levels.  Must look to saliva to get better clinical picture.
Nathan Goodyear

Plasma and salivary steroid hormone resp... [J Strength Cond Res. 2011] - PubMed - NCBI - 0 views

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    plasma and salivary cortisol and Testosterone correlate in study of study assessing overreaching.
Nathan Goodyear

Salivary and plasma cortisol and testosterone r... [J Sports Sci. 2013] - PubMed - NCBI - 0 views

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    Plasma and salivary cortisol and Testosterone levels correlated in small study that looked at post-training hormones changes in athletes.  Cortisol and Testosterone peaked in all experimental groups. 
Nathan Goodyear

Brain-derived Neurotrophic Factor in Human Saliva: ELISA Optimization and Biological Co... - 0 views

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    BDNF can be found and followed in saliva
Nathan Goodyear

Role of Pancreatic Cancer-derived Exosomes in Salivary Biomarker Development - 0 views

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    Saliva is proving to be an exciting medium for functional testing.  Recently, studies have found saliva as a great medium to evaluate for cancer biomarkers.  This study find pancreatic cancer biomarkers in saliva.
Nathan Goodyear

Transdermal delivery of bioidentical proge... [J Pharm Pharm Sci. 2010] - PubMed - NCBI - 0 views

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    Transdermal progesterone levels are quickly transported to saliva.  This quick transport, while serum doesn't equally reflect progesterone, has puzzled many.  Theories have been proposed, yet no answers.   This study looked at whether 5alpha reductase expression in the skin would metabolize the progesterone  and this explain the difference in the two test mediums.  The authors of this study concluded that 5alpha reductase is the not the reason for the difference found in saliva and serum.  the same can be applied to urine as well.
Nathan Goodyear

Steroid Analysis in Saliva: An overview - 0 views

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    No test is perfect. This study analyzes problems with saliva hormone testing.  The authors of this study found saliva testing optimal for cortisol and less so for sex hormones.  Other studies have contradicted this conclusion.
Nathan Goodyear

Steroids in Saliva for Assessing Endocrine Function - 0 views

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    Another study validates saliva as a reliable method for hormone testing.  The author concludes: "steroid concentrations in saliva are independent of flow rate and reflect those in the free fraction in plasma".  This study also discuss potential collection problems and means to resolve them.
Nathan Goodyear

Hormones in saliva: mode of entry and consequent implications for clinical interpretation. - 0 views

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    Saliva valid means to evaluate hormone levels.  This article discussed the means of transport of hormone from serum to salivary cell.  
Nathan Goodyear

Cushing's syndrome: diagnosis and surveillance usi... [Pituitary. 2012] - PubMed - NCBI - 0 views

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    Saliva is "most useful" for those suspected of Cushing's syndrome and those followed after surgery for Cushing's disease.
Nathan Goodyear

Performance of salivary cortisol in the diagnosis of Cushing's syndrome, adrenal incide... - 0 views

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    Salivary hormone testing again shown to gold standard.  This study looked at salivary cortisol levels in those with Cushing's disease, Cushing's syndrome, and with adrenal incidentaloma.   The results make one scratch their head.  The sensitivity and specificities of salivary cortisol were very high, exceeding at least 94% with most > 96 and 97%.  So, why the opposition?  Ignorance I guess.
Nathan Goodyear

Reliability of hypothalamic-pituitary-adrena... [Eur J Epidemiol. 2011] - PubMed - NCBI - 0 views

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    Study finds salivary cortisol testing is "reliable" measure of chronic cortisol production.  This study found similarity between diurnal cortisol and dexamethasone suppressed cortisol and adrenal gland volume based on literature review.
Nathan Goodyear

Salivary cortisol levels and the 2-... [Psychoneuroendocrinology. 2013] - PubMed - NCBI - 0 views

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    This study projected that lower am cortisol in those with long standing depression/anxiety have a more negative long-term prognosis.
Nathan Goodyear

https://dl-web.dropbox.com/get/Public/Research/Salivary%20testosterone.pdf?w=AAA0jQi7Hq... - 0 views

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    salivary testosterone shown to be reliable measure of testosterone in men with suspected low T.
Nathan Goodyear

The role of salivary cortisol measured by liquid chromatography-tandem mass spectrometr... - 0 views

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    LC-MS/MS shown to be useful in evaluation in people with suspected elevated cortisol levels.  In this study, they found the dexamethasone suppression test was required.  The point however is that cortisol is a valid medium and this was with LC-MS/MS instead of the more commonly used ELIZA technique.
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