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Nathan Goodyear

Testosterone-induced muscle hypertrophy is associated with an increase in satellite cel... - 0 views

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    Testosterone increases muscle satellite cells in men.
Nathan Goodyear

High prevalence of Hashimoto's thyroiditis in patients with polycystic ovary syndrome: ... - 0 views

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    Hashimoto's thyroid disease associated with PCOS in women; this was found to be associated with an increased Estradiol:Progesterone ratio.  
Nathan Goodyear

Is serum sex hormone-binding globulin a dominant risk factor for metabolic syndrome? - ... - 0 views

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    Nice study of Chinese men, only abstract available, finds that serum total Testosterone and SHBG were inversely associated with metabolic syndrome in men.  SHBG association was the strongest and TT the weakest.  Free Testosterone had no association in this study.
Nathan Goodyear

Urolithiasis is associated with low serum testosterone levels in men | Otunctemur | Arc... - 0 views

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    low Testosterone is associated with kidney stones in men through increased Metabolic Syndrome.  Better stated, low T is associated with metabolic syndrome and this metabolic dysfunction increased the findings of kidney stones in men.
Nathan Goodyear

Fundamental Aspects of Hypogonadism in the Aging Male - 0 views

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    good discussion of low T effect on a man's metabolism: particularly muscle mass.
Nathan Goodyear

Measurement of fasting salivary insulin and its relationship with serum insulin in chil... - 0 views

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    Salivary insulin correlates well with serum insulin.
Nathan Goodyear

SHBG and testosterone are associated with inflammation in obese men - 0 views

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    Though, obesity is associated with increasing SHBG, inflammation (which is typically elevated in obesity) is negatively associated with SHBG.  CRP was used to evaluate inflammation in this study of obese men.  Testosterone was also negatively associated with inflammation in these men.
Nathan Goodyear

SHBG, Sex Hormones, and Inflammatory Markers in Older Women - 0 views

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    inflammation negatively associated with SHBG in post menopause women.  Interestingly, Estradiol was found to be positively associated.  The inflammatory cytokines evaluated were CRP and IL-6.
Nathan Goodyear

Relationship of serum sex steroid levels and bone turnover markers with bone mineral de... - 0 views

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    Total Testosterone in men decreased by 30% over the lifetime of men in this study compared to 64% decrease in bioavailable Testosterone in men.  Decreased BMD was associated with this loss.  Similar findings for Estrogen was also noted in men.
Nathan Goodyear

Interrelationships of serum testosterone and free testosterone index with FFM and stren... - 0 views

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    Free Testosterone is better indicator of muscle strength than total Testosterone--in this case, free Testosterone index.
Nathan Goodyear

Relationship between low free testosterone levels and loss of muscle mass. - PubMed - NCBI - 0 views

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    low free Testosterone associated with muscle loss in men compared to no association with total Testosterone in Japanese men.
Nathan Goodyear

Estradiol, but not testosterone, heightens cortisol-mediated negative feedback on pulsa... - 0 views

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    INteresting.  Estradiol enhances cortisol negative feedback on ACTH production in both men and women.
Nathan Goodyear

Does Cortisol Inhibit Pulsatile Luteinizing Hormone Secretion at the Hypothalamic or Pi... - 0 views

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    Cortisol inhbits LH secretion at the level of the Pituitary.  The result is a decreased pulse amplitude as a result of decreased pituitary response to GNRH.
Nathan Goodyear

Direct Inhibitory Effect of Glucocorticoids upon Testicular Luteinizing Hormone Recepto... - 0 views

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    glucocorticoids inhibit Testosterone production via down regulation of LH receptors at the level of the testicles.
Nathan Goodyear

Acute Suppression of Circulating Testosterone Levels by Cortisol in Men: The Journal of... - 0 views

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    Cortisol inhibits Testosterone production in men.
Nathan Goodyear

https://www.auanet.org/common/pdf/education/clinical-guidance/Testosterone-Deficiency-W... - 0 views

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    2013 AUA white paper on low Testosterone.
Nathan Goodyear

In Older Men an Optimal Plasma Testosterone Is Associated With Reduced All-Cause Mortal... - 0 views

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    men with Testosterone levels in the middle quintiles had the lowest risk of death compared to low and high quintile levels.  
Nathan Goodyear

Total testosterone may not decline with ageing in Korean men aged 40 years or older. - ... - 0 views

  • Longitudinal change of TT was approximately + 0·8% per year.
  • TT was negatively correlated with body mass index (BMI), waist circumference and glucose
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    In study of 220 Korean mean, there was only a small decline in total Testosterone in men followed from 2002 to 2011.  The change amounted to 0.8% annually.  The level was 18.1 nmol to 17.8 nmol.  TT was inversely associated with BMI, waist and glucose.
Nathan Goodyear

The effect of testosterone replacement on endogenous inflammatory cytokines and lipid p... - 0 views

  • testosterone induced reductions in TNFalpha (-3.1 +/- 8.3 vs. 1.3 +/- 5.2 pg/ml; P = 0.01) and IL-1beta (-0.14 +/- 0.32 vs. 0.18 +/- 0.55 pg/ml; P = 0.08) and an increase in IL-10 (0.33 +/- 1.8 vs. -1.1 +/- 3.0 pg/ml; P = 0.01); the reductions of TNFalpha and IL-1beta were positively correlated
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    Testosterone reduced TNF-alpha and IL-1 beta in men.
Nathan Goodyear

Leydig Cells: Endocrine, Paracrine, and Autocrine Regulation: Endocrine Reviews: Vol 15... - 0 views

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    Older article here, and only abstract available.  TNF-alpha decreased Leydig Testosterone production.
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