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Erich Feldmeier

Spiegelman: Scientists find molecular link to obesity/insulin resistance in mice - 0 views

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    "For this study, the investigators bred mice lacking TRPV4 or administered a drug to deactivate it. In the absence of TRPV4, white cells turned on a set of genes that consume energy to produce heat, rather than storing the energy as excess fat. This "thermogenic" process normally occurs in brown or beige fat (commonly called "good fat"), which is found mostly in small animals and human infants to protect against cold. When the TRPV4-deficient mice were put on a high-calorie diet for several weeks, they did not become obese, and their level of fat cell inflammation and insulin resistance was lowered. "We have identified a target that, when inhibited, can activate beige adipose tissue and suppress inflammation," said Spiegelman."
thinkahol *

Vehicle pollution significantly damages the brain, mouse study suggests - 0 views

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    ScienceDaily (Apr. 13, 2011) - If mice commuted, their brains might find it progressively harder to navigate the maze of Los Angeles freeways. A new study reveals that after short-term exposure to vehicle pollution, mice showed significant brain damage -- including signs associated with memory loss and Alzheimer's disease.
thinkahol *

BPA-exposed male deer mice are demasculinized and undesirable to females, new study finds - 1 views

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    ScienceDaily (June 27, 2011) - While the U.S. Food and Drug Administration notes "some concern" with the controversial chemical BPA, and many other countries, such as Japan and Canada, have considered BPA product bans, disagreement exists amongst scientists in this field on the effects of BPA in animals and humans. The latest research from the University of Missouri shows that BPA causes male deer mice to become demasculinized and behave more like females in their spatial navigational abilities, leading scientists to conclude that exposure to BPA during human development could be damaging to behavioral and cognitive traits that are unique to each sex and important in reproduction.
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