science 2.0

ORCID aims to solve the author/contributor name ambiguity problem in scholarly communications by creating a central registry of unique identifiers for individual researchers and an open and transparent linking mechanism between ORCID and other current author ID schemes.

Data Observation Network for Earth (DataONE) is the foundation of new innovative environmental science through a distributed framework and sustainable cyberinfrastructure that meets the needs of science and society for open, persistent, robust, and secure access to well-described and easily discovered Earth observational data.

Comprehensive protein-protein interaction maps promise to reveal many aspects of the complex regulatory network underlying cellular function. Recently, large-scale approaches have predicted many new protein interactions in yeast. To measure their accuracy and potential as well as to identify biases, strengths and weaknesses, we compare the methods with each other and with a reference set of previously reported protein interactions.

For the average biologist, hands-on literature mining currently means a keyword search in PubMed. However, methods for extracting biomedical facts from the scientific literature have improved considerably, and the associated tools will probably soon be used in many laboratories to automatically annotate and analyse the growing number of system-wide experimental data sets. Owing to the increasing body of text and the open-access policies of many journals, literature mining is also becoming useful for both hypothesis generation and biological discovery. However, the latter will require the integration of literature and high-throughput data, which should encourage close collaborations between biologists and computational linguists.

A new program package, XEASY, was written for interactive computer support of the analysis of NMR spectra for three-dimensional structure determination of biological macromolecules. XEASY was developed for work with 2D, 3D and 4D NMR data sets. It includes all the functions performed by the precursor program EASY, which was designed for the analysis of 2D NMR spectra, i.e., peak picking and support of sequence-specific resonance assignments, cross-peak assignments, cross-peak integration and rate constant determination for dynamic processes. Since the program utilizes the X-window system and the Motif widget set, it is portable on a wide range of UNIX workstations. The design objective was to provide maximal computer support for the analysis of spectra, while providing the user with complete control over the final resonance assignments. Technically important features of XEASY are the use and flexible visual display of lsquostripsrsquo, i.e., two-dimensional spectral regions that contain the relevant parts of 3D or 4D NMR spectra, automated sorting routines to narrow down the selection of strips that need to be interactively considered in a particular assignment step, a protocol of resonance assignments that can be used for reliable bookkeeping, independent of the assignment strategy used, and capabilities for proper treatment of spectral folding and efficient transfer of resonance assignments between spectra of different types and different dimensionality, including projected, reduced-dimensionality triple-resonance experiments.

A new program package, XEASY, was written for interactive computer support of the analysis of NMR spectra for three-dimensional structure determination of biological macromolecules. XEASY was developed for work with 2D, 3D and 4D NMR data sets. It includes all the functions performed by the precursor program EASY, which was designed for the analysis of 2D NMR spectra, i.e., peak picking and support of sequence-specific resonance assignments, cross-peak assignments, cross-peak integration and rate constant determination for dynamic processes. Since the program utilizes the X-window system and the Motif widget set, it is portable on a wide range of UNIX workstations. The design objective was to provide maximal computer support for the analysis of spectra, while providing the user with complete control over the final resonance assignments. Technically important features of XEASY are the use and flexible visual display of lsquostripsrsquo, i.e., two-dimensional spectral regions that contain the relevant parts of 3D or 4D NMR spectra, automated sorting routines to narrow down the selection of strips that need to be interactively considered in a particular assignment step, a protocol of resonance assignments that can be used for reliable bookkeeping, independent of the assignment strategy used, and capabilities for proper treatment of spectral folding and efficient transfer of resonance assignments between spectra of different types and different dimensionality, including projected, reduced-dimensionality triple-resonance experiments.

In the past decade, there have been remarkable advances in proteomic technologies. Mass spectrometry has emerged as the preferred method for in-depth characterization of the protein components of biological systems. Using mass spectrometry, key insights into the composition, regulation and function of molecular complexes and pathways have been gained. From these studies, it is clear that mass-spectrometry-based proteomics is now a powerful 'hypothesis-generating engine' that, when combined with complementary molecular, cellular and pharmacological techniques, provides a framework for translating large data sets into an understanding of complex biological processes.

Google Translate is a free statistical machine translation service provided by Google Inc. to translate a section of text, document or webpage, into another language.

This study aims to utilize modern non-invasive tools in the search for the tomb of Genghis Khan, thus shedding light on Mongolia's rich historical heritage and enabling conservation and education of this rapidly changing landscape.

The Open Dinosaur Project was founded to involve scientists and the public alike in developing a comprehensive database of dinosaur limb bone measurements, to investigate questions of dinosaur function and evolution. We have three major goals:1) do good science; 2) do this science in the most open way possible; and 3) allow anyone who is interested to participate. And by anyone, we mean anyone! We do not care about your education, geographic location, age, or previous background with paleontology. The only requirement for joining us is that you share the goals of our project and are willing to help out in the efforts.

Elsevier is offering $35,000 in prizes and challenging software developers to help more than 15 million researchers, medical professionals, librarians and students navigate scientific content, improve scientific search and discovery, visualize sophisticated data in more insightful and attractive ways and stimulate collaboration.

" Mendeley/PLoS API Binary Battle Build an application with our data, make science more open, win $10,001 and more! What's it all about? PLoS and Mendeley, the popular reference manager and academic social network, teamed up to create a Binary Battle contest to build the best apps that make science more open using PLoS and/or Mendeley's APIs (Application Programming Interface)."

"So I thought it might be useful to post a summary of the current state of open access. There's a lot going on, so even though this essay appears lengthy, it's actually a very brief and incomplete summary of what's happening. I have links to further reading at the end."

We've found that certain search terms are good indicators of flu activity. Google Flu Trends uses aggregated Google search data to estimate flu activity.

A "BioBlitz" is a large scale event that engages large numbers of people with biodiversity, inviting them to get directly involved in surveying and monitoring. During a BioBlitz event scientists and members of the public work together to survey a natural space; seeking, identifying and recording as many species as possible over 24 hours.

CyberTracker is the most efficient method of gps field data collection. You can use CyberTracker on a Smartphone or handheld computer to record any type of observation. CyberTracker, which requires no programming skills, allows you to customize an Application for your own data collection needs.

Help researchers find new drugs for major diseases including Cancer, SARS and HIV.Download the THINK distributed computing software to donate your idle PC time to a worthwhile cause. Why not read our latestnews? This web site requires a browser that supports frames.