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Tiny Sun Activity Changes Affect Earth's Climate | Solar Sunspot Cycle | Space.com - 0 views

  • Even small changes in solar activity can impact Earth's climate in significant and surprisingly complex ways, researchers say.
  • The sun is a constant star when compared with many others in the galaxy
  • ome stars pulsate dramatically, varying wildly in size and brightness and even exploding
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  • In comparison, the sun varies in the amount of light it emits by only 0.1 percent over the course of a relatively stable 11-year-long pattern known as the solar cycle.
  • "the light reaching the top of the Earth's atmosphere provides about 2,500 times as much energy as the total of all other sources combined,"
  • even 0.1 percent of the amount of light the sun emits exceeds all other energy sources the Earth's atmosphere sees combined, such as the radioactivity naturally emitted from Earth's core,
  • Many of the ways the scientists proposed these fluctuations in solar activity could influence Earth were complicated in nature.
  • , solar energetic particles and cosmic rays could reduce ozone levels in the stratosphere
  • in turn alters the behavior of the atmosphere below it, perhaps even pushing storms on the surface off cours
  • "In the lower stratosphere, the presence of ozone causes a local warming because of the breakup of ozone molecules by ultraviolet light,
  • When the ozone is removed, "the stratosphere there becomes cooler, increasing the temperature contrast between the tropics and the polar region
  • contrast in temperatures in the stratosphere and the upper troposphere leads to instabilities in the atmospheric flow west to east.
  • feed the strength of jet streams, ultimately altering flows in the upper troposphere, the layer of atmosphere closest to Earth's surface.
  • alter the distribution of storms over the middle latitudes
  • the sun might have a role to play in this kind of process. I would have to say this would be a very difficult mechanism to prove in climate models
  • climate scientist Gerald Meehl at the National Center for Atmospheric Research and his colleagues suggest that solar variability is leaving a definite imprint on climate, especially in the Pacific Ocean.
  • When researchers look at sea surface temperature data during sunspot peak years, the tropical Pacific showed a pattern very much like that expected with La NiƱa,
  • cyclical cooling of the Pacific Ocean that regularly affects climate worldwide, with sunspot peak years leading to a cooling of almost 1 degree Celsius (1.8 degrees Fahrenheit) in the equatorial eastern Pacific
  • peaks in the sunspot cycle were linked with increased precipitation in a number of areas across the globe, as well as above-normal sea-level pressure in the mid-latitude North and South Pacific.
  • Scientists have also often speculated whether the Maunder Minimum, a 70-year dearth of sunspots in the late 17th to early 18th century, was linked with the coldest part of the Little Ice Age, during which Europe and North America experienced bitterly cold winter
  • This regional cooling might be linked with a drop in the sun's extreme ultraviolet radiation.
  • t, the sun could currently be on the cusp of a miniature version of the Maunder Minimum, since the current solar cycle is the weakest in more than 50 years.
  • Although the sun is the main source of heat for Earth, the researchers note that solar variability may have more of a regional effect than a global one
  • While the sun is by far the dominant energy source powering our climate system, do not assume that it is causing much of recent climate changes. It's pretty stabl
  • Ancient signals of climate such as tree rings and ice cores might also help shed light on the link between the sun and climate
  • Since variations in Earth's magnetic field and atmospheric circulation might disrupt this evidence on Earth,
  • a better long-term record of solar radiation might lie in the rocks and sediments of the moon or Mar
Mars Base

NASA beams Mona Lisa to Lunar Reconnaissance Orbiter at the moon (w/ video) - 0 views

  • To clean up transmission errors introduced by Earth's atmosphere (left), Goddard scientists applied Reed-Solomon error correction (right), which is commonly used in CDs and DVDs.
  • Typical errors include missing pixels (white) and false signals (black). The white stripe indicates a brief period when transmission was paused
  • As part of the first demonstration of laser communication with a satellite at the moon, scientists with NASA's Lunar Reconnaissance Orbiter (LRO) beamed an image of the Mona Lisa to the spacecraft from Earth.
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  • he iconic image traveled nearly 240,000 miles in digital form from the Next Generation Satellite Laser Ranging (NGSLR) station at NASA's Goddard Space Flight Center in Greenbelt, Md., to the Lunar Orbiter Laser Altimeter (LOLA) instrument on the spacecraft.
  • By transmitting the image piggyback on laser pulses that are routinely sent to track LOLA's position, the team achieved simultaneous laser communication and tracking.
  • This is the first time anyone has achieved one-way laser communication at planetary distances
  • "In the near future, this type of simple laser communication might serve as a backup for the radio communication that satellites use
  • In the more distant future, it may allow communication at higher data rates than present radio links can provide
  • Typically, satellites that go beyond Earth orbit use radio waves for tracking and communication
  • LRO is the only satellite in orbit around a body other than Earth to be tracked by laser as well.
  • Precise timing was the key to transmitting the image
  • divided the Mona Lisa image into an array of 152 pixels by 200 pixels
  • Every pixel was converted into a shade of gray, represented by a number between zero and 4,095.
  • Each pixel was transmitted by a laser pulse, with the pulse being fired in one of 4,096 possible time slots during a brief time window allotted for laser tracking
  • he complete image was transmitted at a data rate of about 300 bits per second.
  • The laser pulses were received by LRO's LOLA instrument, which reconstructed the image based on the arrival times of the laser pulses from Earth
  • This was accomplished without interfering with LOLA's primary task of mapping the moon's elevation and terrain and NGSLR's primary task of tracking LRO.
  • The success of the laser transmission was verified by returning the image to Earth using the spacecraft's radio telemetry system.
  • Turbulence in Earth's atmosphere introduced transmission errors even when the sky was clear.
  • To overcome these effects,
  • employed Reed-Solomon coding, which is the same type of error-correction code commonly used in CDs and DVDs.
  • The next step after LLCD is the Laser Communications Relay Demonstration (LCRD), NASA's first long-duration optical communications mission.
Mars Base

Planck's most detailed map ever reveals an almost perfect Universe - 0 views

  • the most detailed map ever created of the cosmic microwave background
  • the relic radiation from the Big Bang
  • was released
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  • revealing the existence of features that challenge the foundations of our current understanding of the Universe
  • The image is based on the initial 15.5 months of data from Planck and is the mission's first all-sky picture of the oldest light in our Universe, imprinted on the sky when it was just 380 000 years old.
  • At that time, the young Universe was filled with a hot dense soup of interacting protons, electrons and photons at about 2700ĀŗC
  • protons and electrons joined to form hydrogen atoms, the light was set free
  • As the Universe has expanded, this light today has been stretched out to microwave wavelengths, equivalent to a temperature of just 2.7 degrees above absolute zero.
  • that correspond to regions of slightly different densities at very early times, representing the seeds of all future structure: the stars and galaxies of today
  • According to the standard model of cosmology, the fluctuations arose immediately after the Big Bang and were stretched to cosmologically large scales during a brief period of accelerated expansion known as inflation.
  • Planck was designed to map these fluctuations across the whole sky with greater resolution and sensitivity than ever before
  • By analysing the nature and distribution of the seeds in Planck's CMB image, we can determine the composition and evolution of the Universe from its birth to the present day
  • because precision of Planck's map is so high, it also made it possible to reveal some peculiar unexplained features that may well require new physics to be understood
  • Since the release of Planck's first all-sky image in 2010, we have been carefully extracting and analysing all of the foreground emissions that lie between us and the Universe's first light
  • revealing the cosmic microwave background in the greatest detail yet
  • One of the most surprising findings is that the fluctuations in the CMB temperatures at large angular scales do not match those predicted by the standard model
  • their signals are not as strong as expected from the smaller scale structure
  • Another is an asymmetry in the average temperatures on opposite hemispheres of the sky
  • This runs counter to the prediction made by the standard model that the Universe should be broadly similar in any direction we look
  • a cold spot extends over a patch of sky that is much larger than expected.
  • The asymmetry and the cold spot had already been hinted at with Planck's predecessor
  • NASA's WMAP mission, but were largely ignored because of lingering doubts about their cosmic origin
  • One way to explain the anomalies is to propose that the Universe is in fact not the same in all directions on a larger scale than we can observe
  • In this scenario, the light rays from the CMB may have taken a more complicated route through the Universe than previously understood, resulting in some of the unusual patterns observed today.
  • ultimate goal would be to construct a new model that predicts the anomalies and links them together
  • we don't know whether this is possible and what type of new physics might be needed
  • the Planck data conform spectacularly well to the expectations of a rather simple model of the Universe, allowing scientists to extract the most refined values yet for its ingredients
  • dark energy, a mysterious force thought to be responsible for accelerating the expansion of the Universe, accounts for less than previously thought.
  • Normal matter that makes up stars and galaxies contributes just 4.9% of the mass/energy density of the Universe
  • Dark matter, which has thus far only been detected indirectly by its gravitational influence, makes up 26.8%, nearly a fifth more than the previous estimate.
  • Planck data also set a new value for the rate at which the Universe is expanding today, known as the Hubble constant
  • At 67.15 kilometres per second per megaparsec, this is significantly less than the current standard value in astronomy
  • The data imply that the age of the Universe is 13.82 billion years.
  • We see an almost perfect fit to the standard model of cosmology, but with intriguing features that force us to rethink some of our basic assumptions
Mars Base

Curiosity Demonstrates New Capability to Scan 360 Degrees for Life Giving Water - and i... - 0 views

  • The science team guiding NASA’s Curiosity Mars Science Lab (MSL) rover have demonstrated a new capability that significantly enhances the robots capability to scan her surroundings for signs of life giving water
  • from a distance
  • the rover appears to have found that evidence for water at the Gale Crater landing site is also more widespread than prior indications.
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  • Mastcam cameras
  • can now also be used as a mineral-detecting and hydration-detecting tool to search 360 degrees around every spot she explores for the ingredients required for habitability and precursors to life
  • Some iron-bearing rocks and minerals can be detected and mapped using the Mastcam’s near-infrared filters
  • scientists used the filter wheels on the Mastcam cameras to run an experiment by taking measurements in different wavelength’s
  • a rock target called ā€˜Knorr’ in the Yellowknife Bay area were Curiosity is now exploring
  • Researchers found that near-infrared wavelengths on Mastcam can be used as a new analytical technique to detect the presence of some but not all types of hydrated minerals
  • The first use of the Mastcam 34 mm camera to find water was at the rock target called ā€œKnorr.ā€
  • see elevated hydration signals in the narrow veins that cut many of the rocks in this area
  • These bright veins contain hydrated minerals that are different from the clay minerals in the surrounding rock matrix
  • Mastcam thus serves as an early detective for water without having to drive up to every spot of interest, saving precious time and effort
  • But Mastcam has some limits
  • It is not sensitive to the hydrated phyllosilicates found in the drilling sample at John Klein
  • Mastcam can use the hydration mapping technique to look for targets related to water that correspond to hydrated minerals
  • Yellowknife Bay basin possesses a significant amount of phyllosilicate clay minerals; indicating an environment where Martian microbes could once have thrived in the distant past.
Mars Base

A new way to lose weight? Study shows that changes to gut microbiota may play role in w... - 0 views

  • by colonizing mice with the altered microbial community, the mice were able to maintain a lower body fat, and lose weight – about 20% as much as they would if they underwent surgery
  • New research
  • has found that the gut microbes of mice undergo drastic changes following gastric bypass surgery
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  • In some ways we were biasing the results against weight loss
  • the mice used in the study hadn't been given a high-fat, high-sugar diet to increase their weight beforehand
  • The question is whether we might have seen a stronger effect if they were on a different diet
  • finding ways to manipulate microbial populations to mimic those effects could become a valuable new tool to address obesity
  • study suggests that the specific effects of gastric bypass on the microbiota contribute to its ability to cause weight loss
  • need to learn a good deal more about the mechanisms by which a microbial population changed by gastric bypass exert its effects,
  • then we need to learn if we can produce these effects – either the microbial changes or the associated metabolic changes – without surgery
  • it may be years before they could be replicated in humans, and that such microbial changes shouldn't be viewed as a way to lose
  • pounds without going to the gym
  • the technique may one day offer hope to dangerously obese people who want to lose weight without going through the trauma of surgery.
  • may not be that we will have a magic pill that will work for everyone who's slightly overweight
  • But if we can, at a minimum, provide some alternative to gastric bypass surgery that produces similar effects, it would be a major advance
  • While there had been hints that the microbes in the gut might change after bypass surgery, the speed and extent of the change came as a surprise to the research team
  • In earlier experiments, researchers had shown that the guts of both lean and obese mice are populated by varying amounts of two types of bacteria
  • When mice undergo gastric bypass surgery, however, it "resets the whole picture
  • those changes occurred within a week of the surgery, and weren't short-lived – the altered gut microbial community remained stable for months afterward
  • the results may hold out the hope for weight loss without surgery
  • future studies are needed to understand exactly what is behind the weight loss seen in mice
  • A major gap in our knowledge is the underlying mechanism linking microbes to weight loss
  • certain microbes
  • found at higher abundance after surgery,
  • think those are good targets for beginning to understand what's taking place
  • the answer may not be the specific types of microbes, but a by-product they excrete.
  • In addition to changes in the microbes found in the gut, researchers found changes in the concentration of certain short-chain fatty acids
  • Other studies
  • have suggested that those molecules may be critical in signaling to the host to speed up metabolism, or not to store excess calories as fat.
  • hope to continue to explore those questions
  • such studies will allow us to understand how host/microbial interactions in general can influence the outcome of a given diet
Mars Base

Heart repair breakthroughs replace surgeon's knife - 0 views

  • Many problems that once required sawing through the breastbone and opening up the chest for open heart surgery now can be treated
  • through a tube
  • These minimal procedures used to be done just to unclog arteries and correct less common heart rhythm problems
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  • Now some patients are getting such repairs for valves, irregular heartbeats, holes in the heart and other defects—without major surgery
  • Doctors even are testing ways to treat high blood pressure with some of these new approaches
  • Instead of opening the chest, we're able to put catheters in through the leg, sometimes through the arm
  • Many patients after having this kind of procedure in a day or two can go home
  • It may lead to cheaper treatment, although the initial cost of the novel devices often offsets the savings from shorter hospital stays
  • Not everyone can have catheter treatment, and some promising devices have hit snags in testing
  • Others on the market now are so new that it will take several years to see if their results last as long as the benefits from surgery do.
  • these procedures have allowed many people too old or frail for an operation to get help for problems that otherwise would likely kill them
  • You can do these on 90-year-old patients
  • also offer an option for people who cannot tolerate long-term use of blood thinners or other drugs to manage their conditions
  • Heart valves
  • Millions of people have leaky heart valves. Each year, more than 100,000 people in the United States alone have surgery for them
  • Without a valve replacement operation, half of these patients die within two years, yet many are too weak to have one.
  • just over a year ago,
  • Edwards Lifesciences Corp. won approval to sell an artificial aortic valve flexible and small enough to fit into a catheter and be wedged inside the bad one
  • At first it was just for inoperable patients. Last fall, use was expanded to include people able to have surgery but at high risk of complications.
  • Catheter-based treatments for other valves also are in testing. One for the mitral valve
  • mixed review by federal Food and Drug Administration advisers this week; whether it will win FDA approval is unclear. It is already sold in Europe
  • Heart rhythm problems
  • Catheters can contain tools to vaporize or "ablate" bits of heart tissue that cause abnormal signals that control the heartbeat
  • Now catheter ablation is being used for the most common rhythm problem—atrial fibrillation, which plagues about 3 million Americans and 15 million people worldwide.
  • Ablation addresses the underlying rhythm problem. To address the stroke risk from pooled blood, several novel devices aim to plug or seal off the pouch
  • The upper chambers of the heart quiver or beat too fast or too slow. That lets blood pool in a small pouch off one of these chambers
  • Clots can form in the pouch and travel to the brain, causing a stroke
  • a tiny lasso to cinch the pouch shut. It uses two catheters that act like chopsticks. One goes through a blood vessel and into the pouch to help guide placement of the device, which is contained in a second catheter poked under the ribs to the outside of the heart. A loop is released to circle the top of the pouch where it meets the heart, sealing off the pouch.
  • A different kind of device
  • sold in Europe and parts of Asia, but is pending before the FDA in the U.S
  • like a tiny umbrella pushed through a vein and then opened inside the heart to plug the troublesome pouch.
  • Early results from a pivotal study released by the company suggested it would miss a key goal, making its future in the U.S. uncertain.
  • Heart defects
  • St. Jude Medical Inc.'s Amplatzer is a fabric-mesh patch threaded through catheters to plug the hole
  • In two new studies, the device did not meet the main goal of lowering the risk of repeat strokes in people who had already suffered one, but some doctors were encouraged by other results
  • Š”logged arteries
  • The original catheter-based treatment—balloon angioplasty—is still used hundreds of thousands of times each year in the U.S. alone
  • A Japanese company, Terumo Corp., is one of the leaders of a new way to do it that is easier on patients—through a catheter in the arm rather than the groin
  • Newer stents that prop arteries open and then dissolve over time, aimed at reducing the risk of blood clots, also are in late-stage testing
  • High blood pressure
  • About
  • 1 billion people worldwide have high blood pressure, a major risk factor for heart attacks
  • Researchers are testing a possible long-term fix for dangerously high pressure that can't be controlled with multiple medications.
  • uses a catheter and radio waves to zap nerves, located near the kidneys, which fuel high blood pressure
  • At least one device is approved in Europe and several companies are testing devices in the United States
Mars Base

Study unravels central mystery of Alzheimer's disease - 0 views

  • Until recently, Polleux's laboratory has been focused not on Alzheimer's research but on the normal development and growth of neurons
  • In 2011
  • reported that AMPK overactivation by metformin, among other compounds, in animal models impaired the ability of neurons to grow output stalks, or axons
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  • Around the same time, separate research groups found clues that AMPK might also have a role in Alzheimer's disease
  • One group reported that AMPK can be activated in neurons by amyloid beta, which in turn can cause a modification of the protein tau in a process known as phosphorylation
  • a postdoctoral research associate
  • began by confirming that amyloid beta, in the small-aggregate ("oligomer") form that is toxic to synapses, does indeed strongly activate AMPK
  • amyloid beta oligomers stimulate certain neuronal receptors, which in turn causes an influx of calcium ions into the neurons
  • that this calcium influx triggers the activation of an enzyme called CAMKK2, which appears to be the main activator of AMPK in neurons
  • AMPK overactivation in neurons is the essential reason for amyloid beta's synapse-harming effect
  • neurons' dendritic spines—the rootlike, synapse-bearing input stalks that receive signals from other neurons
  • scientists showed that amyloid beta oligomers can't cause this dendritic spine loss unless AMPK overactivation occurs—and indeed AMPK overactivation on its own can cause the spine loss
  • the team used J20 mice, which are genetically engineered to overproduce mutant amyloid beta
  • when we blocked the activity of CAMKK2 or AMPK in these neurons, we completely prevented the spine loss
  • Recent studies have shown that amyloid beta's toxicity to dendritic spines depends largely on the presence of tau, but just how the two Alzheimer's proteins interact has been unclear
  • their colleagues are now following up with further experiments to determine what other toxic processes, such as excessive autophagy, are promoted by AMPK overactivation and might also contribute to the long-term aspects of Alzheimer's disease progression
  • also interested in the long-term effects of blocking AMPK overactivation in the J20 mouse model as well as in other mouse models of Alzheimer's disease, which normally develop cognitive deficits at later stages
  • the pharmaceuticals industry who are potentially interested in targeting either CAMKK2 or AMPK
  • show that brain damage in Alzheimer's disease is linked to the overactivation of an enzyme called AMPK
  • Researchers have known for years that people in the earliest stages of Alzheimer's disease begin to lose synapses in certain memory-related brain areas
  • findings, reported in the April
  • Small aggregates of the protein amyloid beta can cause this
  • but how they do so has been a mystery
  • Tangles of tau with multiple phosphorylations ("hyperphosphorylated" tau) are known to accumulate in neurons in affected brain areas in Alzheimer
  • investigate further, to determine whether the reported interactions of AMPK with amyloid beta and tau can in fact cause the damage seen in the brains of Alzheimer's patients
  • In addition
  • findings suggest the need for further safety studies on an existing drug, metformin.
  • , a popular treatment for Type 2 Diabetes, causes AMPK activation.
Mars Base

Printable 'bionic' ear melds electronics and biology - 0 views

  • Scientists at Princeton University used off-the-shelf printing tools to create a functional ear that can "hear" radio frequencies far beyond the range of normal human capability
  • primary purpose was to explore an efficient and versatile means to merge electronics with tissue
  • used 3D printing of cells and nanoparticles followed by cell culture to combine a small coil antenna with cartilage, creating what they term a bionic ear.
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  • Previously, researchers have suggested some strategies
  • That typically happens between a 2D sheet of electronics and a surface of the tissue
  • our work suggests a new approach—to build and grow the biology up with the electronics synergistically and in a 3D interwoven format
  • Last year, a research effort
  • resulted in the development of a "tattoo" made up of a biological sensor and antenna that can be affixed to the surface of a tooth
  • This project, however, is the team's first effort to create a fully functional organ: one that not only replicates a human ability, but extends it using embedded electronics
  • Creating organs using 3D printers is a recent advance; several groups have reported using the technology for this purpose in the past few months
  • this is the first time that researchers have demonstrated that 3D printing is a convenient strategy to interweave tissue with electronics
  • Ear reconstruction "remains one of the most difficult problems in the field of plastic and reconstructive surgery
  • the team turned to a manufacturing approach called 3D printing
  • The finished ear consists of a coiled antenna inside a cartilage structure
  • Two wires lead from the base of the ear and wind around a helical "cochlea" – the part of the ear that senses sound – which can connect to electrodes
  • further work and extensive testing would need to be done before the technology could be used on a patient
  • the ear in principle could be used to restore or enhance human hearing.
  • electrical signals produced by the ear could be connected to a patient's nerve endings, similar to a hearing aid
  • The current system receives radio waves, but he said the research team plans to incorporate other materials, such as pressure-sensitive electronic sensors, to enable the ear to register acoustic sounds
  • researchers used an ordinary 3D printer to combine a matrix of hydrogel and calf cells with silver nanoparticles that form an antenna. The calf cells later develop into cartilage
Mars Base

Scientists report hint of dark matter in first results from $2 billion cosmic ray detec... - 0 views

  • A $2 billion cosmic ray detector on the International Space Station has found the footprint of something that could be dark matter
  • the evidence isn't enough to declare the case closed
  • And after two years, the first evidence came in Wednesday: tantalizing cosmic footprints that seem to have been left by dark matter.
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  • the first results from the Alpha Magnetic Spectrometer, known by its acronym AMS,
  • show evidence of new physics phenomena that could be the strange and unknown dark matter or could be energy that originates from pulsars
  • expects a more definitive answer in a matter of months
  • Unraveling the mystery of dark matter could help scientists better understand the composition of our universe and, more particularly, what holds galaxies together
  • The 7-ton detector with a 3-foot magnet ring at its core was sent into space in 2011
  • The device is transmitting its data to CERN, where it is being analyzed
  • For 80 years scientists have theorized the existence of dark matter but have never actually observed it directly
  • They have looked for it in accelerators that smash particles together at high speed
  • deep underground with special detectors
  • no luck
  • there's a third way: looking in space for the results of rare dark matter collisions
  • If particles of dark matter crash and annihilate each other, they should leave a footprint of positrons—the anti-matter version of electrons—at high energy levels
  • found some. But they could also be signs of pulsars
  • What's key is the curve of the plot of those positrons. If the curve is one shape, it points to dark matter. If it's another, it points to pulsars
  • they should know the curve—and the suspect—soon
  • since its installation on 19 May 2011 it has measured over 30 billion cosmic rays at energies up to trillions of electron volts
  • Its permanent magnet and array of precision particle detectors collect and identify charged cosmic rays passing through AMS from the far reaches of space
  • Over its long duration mission on the ISS, AMS will record signals from 16 billion cosmic rays every year and transmit them to Earth for analysis by the AMS Collaboration.
  • In the initial 18 month period of space operations, from 19 May 2011 to 10 December 2012, AMS analyzed 25 billion primary cosmic ray events
  • Of these,
  • 6.8 million, were unambiguously identified as electrons and their antimatter counterpart, positrons.
  • Positrons are clearly distinguished from this background through the robust rejection power of AMS of more than one in one million
  • Currently, the total number of positrons identified by AMS, in excess of 400,000, is the largest number of energetic antimatter particles directly measured and analyzed from space
  • The exact shape of the spectrum, as shown in Figure 2, extended to higher energies, will ultimately determine whether this spectrum originates from the collision of dark matter particles or from pulsars in the galaxy
  • by measuring the ratio between positrons and electrons and by studying the behavior of any excess across the energy spectrum, a better understanding of the origin of dark matter and other physics phenomena can be obtained
Mars Base

Chipmaker Races to Save Stephen Hawking's Speech as His Condition Deteriorates: Sc... - 0 views

  • Renowned physicist Stephen Hawking has long relied on technology to help him connect with the outside world despite the degenerative motor neuron disease he has battled for the past 50 years
  • a highly respected computer scientist indicated at last week’s International Consumer Electronics Show (CES) that he and his team may be close to a breakthrough that could boost the rate at which the physicist communicates, which has fallen to a mere one word per minute in recent years.
  • For the past decade Hawking has used a voluntary twitch of his cheek muscle to compose words and sentences one letter at a time that are expressed through a speech-generation device connected to his computer.
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  • Each tweak stops a cursor that continuously scans text on a screen facing the scientist.
  • Intel chief technology officer
  • noted that Hawking can actually make a number of other facial expressions as well that might also be used to speed up the rate at which the physicist conveys his thoughts
  • Even providing Hawking with two inputs would give him the ability to communicate using Morse code
  • Intel has since the late 1990s supplied Hawking with technology to help the scientist express himself
  • The latest chapter in their work together began in late 2011 when Hawking reached out to
  • inform
  • the Intel co-founder and father of Moore’s law that the physicist’s ability to compose text was slowing and inquiring whether Intel could help.
  • met with Hawking early last year around the time of the latter’s 70th birthday celebration in Cambridge, where the Intel CTO was one of the speakers
  • After meeting with Hawking
  • he wondered whether his company’s processor technology could restore the scientist’s ability to communicate at five words per minute, or even increase that rate to 10
  • Intel is now working on a system that can use Hawking’s cheek twitch as well as mouth and eyebrow movements to provide signals to his computer
  • built a new, character-driven interface in modern terms that includes a better word predictor
  • company is also exploring the use of facial-recognition software to create a new user interface for Hawking that would be quicker than selecting individual letters or words
  • A black box beneath his wheelchair contains an audio amplifier, voltage regulators and a USB hardware key that receives the input from an infrared sensor on Hawking’s eyeglasses, which detects changes in light as he twitches his cheek
  • current setup includes a tablet PC with a forward-facing Webcam that he can use to place Skype calls
  • A hardware voice synthesizer sits in another black box on the back of the chair and receives commands from the computer via a USB-based serial port
  • Intel’s work with Hawking is part of the company’s broader research into smart gadgets as well as assistive technologies for the elderly
  • The key to advancing smart devices—which have been at a plateau over the past five or six years—is context awareness
  • Devices will really get to know us the way a friend would, understanding how our facial expressions reflect our mood
  • Intel’s plan for identifying personal context requires a combination of hardware sensors—camera, accelerometer, microphone, thermometer and others
  • with software that can check one’s personal calendar, social networks and Internet browsing habits, to name a few.
  • use this [information] to reason your current context and what's important at any given time [and deliver] pervasive assistance
  • One approach to ā€œpervasive assistanceā€ is the Magic Carpet, a rug that Intel and GE developed with embedded sensors and accelerometers that can record a person’s normal routine and even their gait, sounding an alert when deviations are detected.
  • Such assistance will anticipate our needs, letting us know when we are supposed to be at an appointment and even reminding us to carry enough cash when running certain errands
Mars Base

Specialized nerve fibers send touchy-feely messages to brain | Body & Brain | Scien... - 0 views

  • Some nerve fibers seem to love a good rubdown. These tendrils, which spread across skin like upside-down tree roots, detect smooth, steady stroking and send a feel-good message to the brain
  • The results are the latest to emphasize the strong and often underappreciated connection between emotions and the sensation of touch
  • ā€œIt may seem frivolous to be studying massage neurons in mice, but it raises a profound issue — why do certain stimuli feel a certain way?ā€
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  • . Earlier studies in people suggested that a particular breed of nerve fibers detects a caress and carries that signal to the brain
  • scientists hadn’t been able to directly link this type of neuron to good feelings, either in people or in animals.
  • Directly linking these neurons with pleasure clarifies the importance of touch
  • The new study relied on mice genetically engineered so that a select population of nerve cells would glow when they sensed a caress
  • These neurons,
  • possessed the attributes of massage sensors, but they stubbornly refused to respond to touch in experiments in lab dishes
  • by touching the genetically engineered animals’ skin, the researchers were able to study these cells in live mice.
  • A harsher poke, with a more focused point of pressure, didn’t elicit a reaction from the cells
  • These neurons, which all carry a protein called MRGPRB4, seem tuned to detect a steady stroke
  • the researchers tested whether this stroke felt good to mice
  • the scientists used a different kind of genetically engineered mouse, one with caress-sensitive neurons that a drug could activate
  • When the researchers dispensed the drug in a particular room, the mice soon learned to prefer that room over others
  • associating it with the presumably enjoyable sensation of being stroked
  • not yet clear whether the nerve fibers in the mice have exact analogs in humans,
  • new view of caress detection
  • offers a deeper understanding of touch.
Mars Base

Study of friction reveals clues about arthritis - 0 views

  • A new, noninvasive, and low-cost method for the early detection and monitoring of osteoarthritis (arthritis caused by wear and tear) may be on its way
  • By studying patterns of friction between cartilage pads, the researchers discovered a different type of friction that is more likely to cause wear and damage
  • work suggests ways to detect this friction, and points to new research directions for getting to the root cause of arthritis
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  • Imagine going to the doctor for your aching knees
  • what if your doctor could actually listen to your body, monitoring the way your knees sound as they bend and flex
  • an instrument called a Surface Forces Apparatus (SFA), a device that measures the adhesion and friction forces between surfaces—in this case cartilage, the pad of tissue that covers the ends of bones at a joint.
  • degeneration of cartilage is the most common cause of osteoarthritis: The pads wear away, leaving bone grinding against bone
  • researchers found is that it isn't just any kind of friction that leads to the irreversible wear and tear on the material
  • currently believed that a high-friction force, or 'coefficient of friction,' is the primary factor in surface wear and damage
  • found is that this is not the case
  • The critical feature is not a high-friction force, but what is known as "stick-slip" friction, or, sometimes, "stiction."
  • Both are characterized by surfaces that initially stick together, and then accelerate away quickly once the static friction force is overcome
  • With stick-slip friction, the surfaces eventually pull slightly apart and slide across each other, stick again, and pull apart, causing jerky movements.
  • That's when things get damaged microscopically
  • Stick-slip is a common phenomenon. It is responsible for everything from computer hard drive crashes and automobile failures, to squeaking doors and music
  • same thing happens with a violin string
  • Even if you're pulling the bow steadily, it's moving in hundreds or thousands of little jerks per second, which determine the sound you hear
  • Each little jerk, no matter how submicroscopic, is an impact, and over time the accumulation of these impacts can deform surfaces, causing irreparable damage—first microscopically, then growing to macroscopic
  • it's not easy to tell the difference between types of friction at the microscopic level
  • Smooth-sliding joints might feel the same as those undergoing stiction, or the even more harmful stick-slip, especially in the early stages of arthritis
  • when measured with an ultra-sensitive and high-resolution instrument like the SFA, each type of friction revealed its own characteristic profile
  • Smooth-sliding joints yielded an almost smooth constant line (friction force or friction trace
  • with stiction showed up as a peak, as the "sticking" was being overcome, followed by a relatively smooth line
  • stick-slip shows the jagged saw-tooth profile of two surfaces repeatedly pulling apart, sticking, and pulling apart again
  • these measurements could be recorded by placing an acoustic or electric sensing device around joints, giving a signal similar to an EKG.
  • this could be a good way to measure and diagnose damage to the cartilage
  • to measure the progression, or even the early detection of symptoms related to arthritis
  • Early detection of conditions like arthritis has been a priority for many years
  • the functioning of joints is more complicated
  • scientists will continue their work by studying synovial fluid—the lubricating fluid between two cartilage surfaces in joints
  • plays a major role in whether or not the surfaces wear and tear, and the synergistic roles of the different molecules (proteins, lipids, and polymers
  • all involved in lubricating and preventing damage to our joints.
  • a number of directions to take, both fundamental and practical
  • it looks as if we need to focus our research on finding ways to prevent stick-slip motion, rather than lowering the friction force
Mars Base

Green tea and red wine extracts interrupt Alzheimer's disease pathway in cells - 0 views

  • Natural chemicals found in green tea and red wine may disrupt a key step of the Alzheimer's disease pathway
  • Alzheimer's disease is characterised by a distinct build-up of amyloid protein in the brain
  • clumps together to form toxic, sticky balls of varying shapes
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  • These amyloid balls latch on to the surface of nerve cells in the brain by attaching to proteins on the cell surface called prions
  • investigate whether the precise shape of the amyloid balls is essential for them to attach to the prion receptors
  • if so, we wanted to see if we could prevent the amyloid balls binding to prion by altering their shape, as this would stop the cells from dying
  • The team formed amyloid balls in a test tube and added them to human and animal brain cells
  • When we added the extracts from red wine and green tea, which recent research has shown to re-shape amyloid proteins, the amyloid balls no longer harmed the nerve cells
  • this was because their shape was distorted, so they could no longer bind to prion and disrupt cell function
  • showed, for the first time, that when amyloid balls stick to prion, it triggers the production of even more amyloid
  • the team's next steps are to understand exactly how the amyloid-prion interaction kills off neurons
  • that this will increase our understanding of Alzheimer's disease even further, with the potential to reveal yet more drug targets,
  • While these early-stage results should not be a signal for people to stock up on green tea and red wine, they could provide an important new lead in the search for new and effective treatments
Mars Base

Smallest Exoplanet Yet Discovered by 'Listening' to a Sun-like Star - 0 views

  • Scientists have discovered a new planet orbiting a Sun-like star, and the exoplanet is the smallest yet found in data from the Kepler mission
  • Kepler-37b, is smaller than Mercury, but slightly larger than Earth’s Moon
  • discovery came from a collaboration between Kepler scientists and a consortium of international researchers who employ asteroseismology
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  • measuring oscillations in the star’s brightness caused by continuous star-quakes, and turning those tiny variations in the star’s light into sounds
  • The bigger the star, the lower the frequency, or ā€˜pitch’ of its song
  • The measurements made by the astroseismologists allowed the Kepler research team to more accurately measure the tiny Kepler-37b
  • revealing two other planets in the same planetary system: one slightly smaller than Earth and one twice as large
  • Kepler-37b is very likely a rocky planet with no atmosphere or water, similar to Mercury
  • ā€œThe detection of such a small planet shows for the first time that stellar systems host planets much smaller as well as much larger than anything we see in our own Solar System.ā€
  • host star, Kepler-37, is about 210 light-years from Earth
  • All three planets orbit the star at less than the distance Mercury is to the Sun
  • Kepler-37b orbits every 13 days at less than one-third Mercury’s distance from the Sun
  • estimated surface temperature of this smoldering planet, at more than 800 degrees Fahrenheit (700 degrees Kelvin
  • hot enough to melt the zinc in a penny
  • Kepler-37c and Kepler-37d, orbit every 21 days and 40 days, respectively
  • The size of the star must be known in order to measure the planet’s size accurately
  • scientists examined sound waves generated by the boiling motion beneath the surface of the star
  • The technique for stellar seismology is analogous to how geologists use seismic waves generated by earthquakes to probe the interior structure of Earth
  • sound waves travel into the star and bring information back up to the surface
  • waves cause oscillations that Kepler observes as a rapid flickering of the star’s brightness
  • barely discernible, high-frequency oscillations in the brightness of small stars are the most difficult to measure
  • why most objects previously subjected to asteroseismic analysis are larger than the Sun
  • Kepler-37 has a radius just three-quarters of the Sun
  • the radius of the star is known to 3 percent accuracy, which translates to exceptional accuracy in the planet’s size.
  • this discovery took a long time to verify, as the signature of this very small exoplanet was hard to confirm
  • Kepler is sending astronomers photometry data that’s ā€œprobably the best we’ll see in our lifetimes
  • uncovered a planet smaller than any in our solar system orbiting one of the few stars that is both bright and quiet, where signal detection was possible
Mars Base

Liftoff! Delta IV Launches Next Generation GPS Satellite - 0 views

  • A Delta IV rocket launched
  • sending a next-generation Global Positioning System satellite into orbit
  • satellite that will be part of the GPS system that is used by both civilians and the military
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  • will replace a 19-year-old navigation satellite in the global system that includes 31 operational satellites on-orbit which broadcast position
  • the third of 12 planned launches to provide improved GPS signals
  • featuring improved anti-jam technology, more precise atomic clocks, an upgraded civilian channel for commercial aviation and on-board processors that can be reprogrammed in flight
Mars Base

InteraXon looking for crowdfunding for Muse, a brainwave-sensor headband (w/ Video) - 0 views

  • crowd source funding site
  • Muse is a headband device based on electroencephalography (EEG) sensor technology combined with a sophisticated smartphone app that allows the wearer's brainwaves to be monitored.
  • sensors
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  • monitor alpha (resting state) and beta (active state) brainwaves
  • converted to a signal that is broadcast, via Bluetooth technology, to the user's smartphone
  • claims that Muse can be used to learn new ways to relax, recognize lapses in concentration, build self-confidence, and gain more control of one's thoughts, overall
  • app includes a series of lessons and exercises designed to teach the user how to manipulate brain waves using visual feedback
Mars Base

Scientists find possible cause of movement defects in spinal muscular atrophy - 0 views

  • abnormally low level of a protein in certain nerve cells is linked to movement problems that characterize the deadly childhood disorder spinal muscular atrophy, new research in animals suggests
  • previous research has established the disease’s genetic link to SMN in motor neurons, scientists haven’t yet uncovered how this lack of SMN does so much damage
  • showed in zebrafish that when SMN is missing – in cells throughout the body as well as in motor neurons specifically – levels of a protein called plastin 3 also decrease
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  • When the researchers added plastin 3 back to motor neurons in zebrafish that were genetically altered so they couldn’t produce SMN, the zebrafish regained most of their swimming abilities movement that had been severely limited by their reduced SMN. These findings tied the presence of plastin 3 – alone, without SMN – to the recovery of lost movement
  • without SMN in their cells still eventually died, so the addition of plastin 3 alone is not a therapeutic option
  • using animal studies to pinpoint the role of plastin 3 in this disease
  • In zebrafish genetically altered so they don’t produce SMN, plastin 3 levels remained low, as well.
  • lowering plastin 3 first in the fish – SMN was unaffected. This showed that the plastin 3 decrease occurred only when SMN was lowered first
  • SMN production was stimulated in zebrafish initially lacking the protein, plastin 3 levels were restored as well
  • researchers determined that decreased SMN influences plastin 3 production at a late point in the process called translation, when amino acids are strung together to form the protein’s initial shape
  • lack of SMN creates conditions in which too little plastin 3 is made to complete the protein’s normal functions – in these animals, the reduction was about four-fold
  • maybe SMN is affecting translation of other proteins that could be contributing to spinal muscular atrophy
  • That hasn’t been shown before
  • examination of zebrafish motor neurons suggested that decreased plastin 3 affects these cells in at least two ways
  • damaging axons, branch-like extensions that allow for communication among nerve cells
  • destabilizing synapses, structures through which those signals pass
  • result of the added plastin 3, the fish recovered their ability to turn and swim, movements they were previously unable to make.
  • rescued axons, synaptic proteins and behavior all by putting plastin 3 back in motor neurons,ā€ she said. ā€œThat’s very encouraging.ā€
Mars Base

Opportunity rover rolling again after fifth Mars winter - 0 views

  • NASA's Mars Exploration Rover Opportunity drove about 12 feet (3.67 meters) on May 8, 2012, after spending 19 weeks working in one place while solar power was too low for driving during the Martian winter.
  • While at Greeley Haven for the past 19 weeks, Opportunity used the spectrometers and microscopic imager on its robotic arm to inspect more than a dozen targets within reach on the outcrop
  • Radio Doppler signals from the stationary rover during the winter months served an investigation of the interior of Mars by providing precise information about the planet's rotation
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  • Opportunity will look back with its panoramic camera to acquire multi-filter imaging of the surface targets it studied on Greeley Haven.
  • rover team will also check that the power supply still looks sufficient with the rover at a reduced tilt.
  • first drive since Dec. 26, 2011, took the rover about 12 feet (3.67 meters) northwest and downhill on Tuesday, May 8.
  • exploring the Meridiani region of Mars since landing in January 2004
  • arrived at the Cape York section of the rim of Endeavour Crater in August 2011
  • studying rock and soil targets on Cape York since then.
  • next goal is a few meters farther north on Cape York, at a bright-looking patch of what may be dust
  • haven't been able to see much dust in Meridiani
  • Endeavour Crater offers Opportunity a setting for plenty of productive
  • crater is 14 miles (22 kilometers) in diameter
  • Unless wind removes some dust from Opportunity's solar array, allowing more sunlight to reach the solar cells, the rover will need to work during the next few weeks at locations with no southward slope
  • kept a northward tilt of about 15 degrees in recent months at its winter haven
  • favorably angled toward the winter sun low in the northern sky
Mars Base

Planet-Hunting Kepler Mission Extended Through 2016 | Alien Planets | Space.com - 0 views

  • Kepler mission, which has discovered more than 2,300 potential alien planets to date,
  • slated to run out this November
  • launched in March 2009 on
  • ...4 more annotations...
  • finding 61 confirmed alien planets to date
  • members have estimated that the vast majority of these candidates — 80 percent or more — will likely end up being the real deal.
  • artist's conception illustrates Kepler-22b, a planet known to comfortably circle in the habitable zone of a sun-like star. CREDIT: NASA/Ames/JPL-Caltech
  • Seeing more transits will also increase the signal-to-noise ratio for closer-in planets, allowing more of them to be detected, researchers have said
Mars Base

Nanotechnology breakthrough could dramatically improve medical tests - 0 views

  • The material consists of a series of glass pillars in a layer of gold. Each pillar is speckled on its sides with gold dots and capped with a gold disk. Each pillar is just 60 nanometers in diameter, 1/1,000th the width of a human hair
  • laboratory test used to detect disease and perform biological research could be made more than 3 million times more sensitive
  • increased performance could greatly improve the early detection of cancer, Alzheimer's disease and other disorders by allowing doctors to detect far lower concentrations of telltale markers than was previously practical.
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  • The greater the glow, the more of the biomarker is present.
  • if the amount of biomarker is too small, the fluorescent light is too faint to be detected, setting the limit of detection
  • major goal in immunoassay research is to improve the detection limit.
  • involves a common biological test called an immunoassay, which mimics the action of the immune system to detect the presence of biomarkers
  • When biomarkers are present
  • the immunoassay test produces a fluorescent glow (light) that can be measured in a laboratory
  • tackled this limitation by using nanotechnology to greatly amplify the faint fluorescence from a sample
  • fashioning glass and gold structures so small they could only be seen with a powerful electron microscope
  • able to drastically increase the fluorescence signal compared to conventional immunoassays, leading to a 3-million-fold improvement in the limit of detection
  • key to the breakthrough lies in a new artificial nanomaterial called D2PA
  • a thin layer of gold nanostructures surrounded glass pillars just 60 nanometers in diameter.
  • A nanometer is one billionth of a meter; that means about 1,000 of the pillars laid side by side would be as wide as a human hair.
  • e pillars are spaced 200 nanometers apart and capped with a disk of gold on each pillar
  • sides of each pillar are speckled with even tinier gold dots about 10 to 15 nanometers in diameter
  • a sample such as blood, saliva or urine is taken from a patient and added to small glass vials containing antibodies that are designed to "capture" or bind to biomarkers of interest in the sample
  • Another set of antibodies that have been labeled with a fluorescent molecule are then added to the mix
  • biomarkers are not present in the vials
  • fluorescent detection antibodies do not attach to anything and are washed away
  • immunoassays are commonly used in drug discovery and other biological research.
  • plays a significant role in other areas of chemistry and engineering, from light-emitting displays to solar energy harvesting
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