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Ultrathin flexible brain implant offers unique look at seizures - 0 views

  • Researchers funded by the National Institutes of Health have developed a flexible brain implant that could one day be used to treat epileptic seizures
  • a type of electrode array that conforms to the brain's surface – to take an unprecedented look at the brain activity underlying seizures
  • Someday, these flexible arrays could be used to pinpoint where seizures start in the brain and perhaps to shut them down
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  • These flexible electrode arrays could significantly expand surgical options for patients with drug-resistant epilepsy
  • In an animal model, the researchers saw spiral waves of brain activity not previously observed during a seizure
  • Similar waves are known to ripple through cardiac muscle during a type of life-threatening heart rhythm called ventricular fibrillation.
  • A stimulating electrode array might one day be designed to suppress seizure activity, working like a pacemaker for the brain
  • The brain contains billions of interconnected neurons that normally transmit electrical pulses
  • During a seizure, these pulses occur in abnormal, synchronized, rapid-fire bursts that can cause convulsions, loss of consciousness and other symptoms
  • is made of a pliable material that is only about one quarter the thickness of a human hair
  • It contains 720 silicon nanomembrane transistors in a multiplexed 360-channel array, which allow for minimal wiring and dense packing of the electrodes
  • The flexibility of the array allows it to conform to the brain's complex shape, even reaching into grooves that are inaccessible to conventional arrays
  • the array could be rolled into a tube and delivered into the brain through a small hole rather than by opening the skull
  • The researchers tested the flexible array on cats. Although mice and rats are used for most neuroscience research, cats have larger brains that are anatomically more like the human brain, with simplified folds and grooves
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Exceptional Memory Linked To Bulked-up Parts Of Brain - Science News - 0 views

  • some real-life people can remember every day of their lives in detail
  • Those superrememberers have more bulk in certain parts of their brains, possibly explaining the remarkable ability to recall minutiae from decades ago
  • brain region involved in such incredible recall has been implicated in obsessive-compulsive disorder
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  • OCD and superior memory might have a common architecture in the brain
  • Scientists have long studied people with memory deficits, but there haven’t been many studies on people with exceptional memories
  • 11 people who scored off the charts for autobiographical memory. These people could effortlessly remember, for instance, what they were doing on November 2, 1989, and could also tell you that it was a Thursday
  • Using brain scans, researchers found that people with supermemories had larger brain regions associated with memory
  • a brain structure called the lentiform nucleus, a cone-shaped mass in the core of the brain, was bigger in people with exceptional memories
  • This brain area has been linked to obsessive-compulsive disorder
  • The subjects haven’t been clinically evaluated for OCD, but LePort says that there are some similarities
  • The ability to organize their memories by dates seems to relieve anxiety
  • These people could encode information more effectively, or have a better system of retrieving it, or both
  • Though no genetic tests have been performed, some of the volunteers have reported that family members share extraordinary powers of recall
  • The volunteers are now keeping detailed diaries, so that the scientists can test whether particular kinds of memories are better suited to recollection. People might be better at remembering emotional memories, for instance
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