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IF YOU want to lose weight, convince yourself that everything you eat is highly calorific. It could lower your levels of a hunger hormone, potentially suppressing your appetite. Alia Crum at Yale University and her colleagues gave 46 healthy volunteers the same 380-calorie milkshake but were told it was either a sensible, low-calorie choice or an indulgent, high-calorie one. The team also measured levels of ghrelin - a hormone released by the stomach when we are hungry - before and after participants drank the shake. Ghrelin levels have been shown to spike half an hour before mealtimes and return to normal after eating. Volunteers who thought they had indulged showed significantly greater drops in ghrelin levels than those who thought they had consumed less. The authors suggest that merely thinking that one has eaten something unhealthy can quell hunger pangs and perhaps help curb overeating (Health Psychology, DOI: 10.1037/a0023467). The study shows that food labels can affect consumption in unexpected ways, says David Cummings, an endocrinologist at the University of Washington in Seattle.

avoid thinking locally and specifically and practice thinking globally, objectively and abstractly, and increased self-control should follow.

The English city of Manchester has come up with a simple formula it hopes will help keep its citizens trim: eat right, get stuff. Exercise, get more stuff.

Fats in foods like potato chips and french fries make them nearly irresistible because they trigger natural marijuana-like chemicals in the body called endocannabinoids, researchers at the University of California, Irvine, have found. The researchers discovered that when rats tasted something fatty, cells in their upper gut started producing endocannabinoids, while sugars and proteins did not have this effect. How fats create, like, a buzz It starts on the tongue, where fats in food generate a signal that travels first to your brain, and then through a nerve bundle called the vagus to your intestines. There, the signal stimulates the production of endocannabinoids, which initiates a surge in cell signaling that prompts you to totally pig out - probably by initiating the release of digestive chemicals linked to hunger and satiety that compel us to eat more. And that leads to obesity, diabetes and cancer, the researchers said. But they suggest it might be possible to curb this process by obstructing endocannabinoid activity: for example, by using drugs that "clog" cannabinoid receptors. The trick: bypassing the brain to avoid creating anxiety and depression (which happens when endocannabinoid signaling is blocked in the brain). I'm guessing McDonald's won't be adding that drug to their fries. Ref.: Daniele Piomelli, et al., An endocannabinoid signal in the gut controls dietary fat intake, PNAS, 2011; in press

Everything we do is for the purpose of altering consciousness. We form friendships so that we can feel certain emotions, like love, and avoid others, like loneliness. We eat specific foods to enjoy their fleeting presence on our tongues. We read for the pleasure of thinking another person's thoughts. Every waking moment-and even in our dreams-we struggle to direct the flow of sensation, emotion, and cognition toward states of consciousness that we value.Drugs are another means toward this end. Some are illegal; some are stigmatized; some are dangerous-though, perversely, these sets only partially intersect. There are drugs of extraordinary power and utility, like psilocybin (the active compound in "magic mushrooms") and lysergic acid diethylamide (LSD), which pose no apparent risk of addiction and are physically well-tolerated, and yet one can still be sent to prison for their use-while drugs like tobacco and alcohol, which have ruined countless lives, are enjoyed ad libitum in almost every society on earth. There are other points on this continuum-3,4-methylenedioxymethamphetamine (MDMA or "Ecstasy") has remarkable therapeutic potential, but it is also susceptible to abuse, and it appears to be neurotoxic.[1]One of the great responsibilities we have as a society is to educate ourselves, along with the next generation, about which substances are worth ingesting, and for what purpose, and which are not. The problem, however, is that we refer to all biologically active compounds by a single term-"drugs"-and this makes it nearly impossible to have an intelligent discussion about the psychological, medical, ethical, and legal issues surrounding their use. The poverty of our language has been only slightly eased by the introduction of terms like "psychedelics" to differentiate certain visionary compounds, which can produce extraordinary states of ecstasy and insight, from "narcotics" and other classic agents of stupefaction and abuse.

What on earth could be bad about eating low-fat foods? Quite a lot, as it turns out. Food psychologists Brian Wansink and Pierre Chandon (2006) have discovered that foods labeled as "low fat" can lead to increased consumption and contribute significantly to obesity.

In many cases, wine drinkers will actually rate the identical wine higher when it's presented in a fancier bottle. So if presentation matters, then perhaps the presentation of wine could actually affect the taste of the food it's served with. This is the premise of a study by Brian Wansink, Collin Payne, and Jill North.

Interesting & quick post on research into the neurological basis of reading.