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"Designing drugs" sounds trendy, but it accurately describes how some remarkably effective drugs are developed. In this case study we'll follow the steps of drug design, from initial research on the targeted disease, to the drug's use in humans. Gleevec (STI-571) is our example.

After apologizing for an American science experiment in which Guatemalan prisoners and mentally ill patients were deliberately infected with STDs more than 60 years ago, U.S. officials called on the Institute of Medicine to launch a full investigation. NBC Chief Science Correspondent Robert Bazell reports.