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"This case study introduces students to Duchenne muscular dystrophy (DMD) and its underlying genetics, cell biology, and some of the associated biochemical pathways.  DMD is an X-linked disorder characterized by progressive muscle weakness and wasting due to the absence of a protein called dystrophin, which in turn causes degeneration of skeletal and cardiac muscle. There is currently no established cure for this disease.  The case follows the progress of "Casey," an undergraduate student who has just declared her biology major and is interested in expanding her scientific understanding of the different fields of biology. The case is organized in three parts: genetics, cell biology, and biochemistry, each exploring DMD through its unique lens. Throughout the case, Casey is presented with multiple outlets of information, including class lectures, direct e-mail interaction with a professor, scientific journals and websites, from which she (and any student engaged with the case) gathers knowledge about DMD."

Flinn Scientific has launched a website with an extensive amount of resources specifically developed to help teachers, students and parents continue their science education journey - even if that learning is taking place outside the classroom or laboratory environment. Examples of some of the resources we have developed: Free video labs with related teacher and student guides to help students at home continue making progress on key science topics More than 40 free, easy and fun-to-do activities that use commonly available materials to encourage science investigation in the home Flinn's unique digital learning solutions to facilitate seamless science learning. These online solutions are the perfect way to efficiently scale curriculum in an at-home setting - also free of charge On call scientists: over the coming days, we will be releasing video based lab experiments conducted by our scientific staff and broadcast from our studio with live events. As part of each live event, we will have our full team of scientists available to answer questions from teachers and students participating online - also free of charge and highly interactive and engaging. Be sure to check out our online calendar indicating the live schedule

Almost every cell in the human body has the same DNA sequence. So why is a heart cell different from a brain cell? Cells use their DNA code in different ways, depending on their jobs - just as the orchestra in this video can perform one piece of music in many different ways. The combination of changes in gene expression in a cell is called its epigenome

Within every cell in our body, two copies of a tumor suppressor gene called BRCA1 are tasked with regulating the speed at which cells divide. Michael Windelspecht explains how these genes can sometimes mutate, making those cells less specialized and more likely to develop into cancer.

When plastic trash degrades in the ocean, it doesn't just go away: It becomes countless tiny particles, and little creatures called larvaceans sweep it up--and into the food chain.

hat is color blindness? A color festival. No. Color blindness or color deficiency is a vision problem. Now, our eyes have light sensitive cells called rods and cones. Can I put ice cream on these cones? You are just unbelievable. Rods are responsible for black and white vision. They do not detect color. Whereas, cones detect color. There are three types of cones. One cone perceives red light, another perceives green and the third perceives blue. Together, these cones help us to see the whole spectrum of colors. Now in some cases, when one or more types of cones do not work properly, it causes color blindness. People with such deficiency have difficulty in distinguishing between certain colors or shades. For example, in red-green color blindness, the apple tree may appear like this.

Every year during the foodless winter months, bears enter their den and lapse into a state of extended dormancy and slumber (called hibernation). For the next 130+ consecutive days they do not drink, eat, defecate, or urinate. Rarely do they die from starvation, dehydration, or poisoning from waste buildup while hibernating. How do bears prepare for this period of starvation coupled with significant weight loss? Bears are not only the champions of winter rest, but are also the undisputed champions of non-stop summer eating. They are constantly on the move during late spring and all summer long into late autumn oftentimes covering great distances over diverse habitats in their incessant search for locally and seasonally available food. In this case study, students learn the basics about bear denning, hibernation energetics, the differences in size of bear home ranges, and the nutritional landscape they must navigate to prepare for the long months of winter inactivity and caloric deprivation. The case is suitable for a wide audience, including majors or non-majors in lower- or upper-level undergraduate courses in environmental science, ecology, biology, or wildlife science.

But if Gánti's theories had been more widely known during the communist era, he might now be acclaimed as one of the most innovative biologists of the 20th century. That's because he devised a model of the simplest possible living organism, which he called the chemoton, that points to an exciting explanation for how life on Earth began.

This activity guides the analysis of a published scientific figure from a study that modeled the impact of an infectious fungal disease on a bat population. In 2006, a disease called white-nose syndrome (WNS) began wiping out bat populations in North America. Because many of these bats eat insect pests, the spread of WNS may devastate ecosystems and increase pest control costs. In this study, scientists mathematically modeled the effects of WNS to estimate extinction probabilities for the little brown bat (Myotis lucifugus) population in the northeastern United States. This figure shows these probabilities projected for five annual rates of population decline. Each projection is simulated up to 100 years after WNS emerged in the population. The "Educator Materials" document includes a captioned figure, background information, graph interpretation, and discussion questions. The "Student Handout" includes a captioned figure and background information.

In this case study, students follow "Mr. Okoro" as he makes the long journey with his sick daughter "Ada" to seek medical attention at the nearest clinic in Enugu, Nigeria. It is the rainy season, and "Dr. Fabian" from the Division of Parasitic Diseases and Malaria has been called in to investigate a suspected outbreak of malaria. Students learn about the circumstances in Ada's background that may have led to her illness, and then adopt the perspective of Dr. Fabian as she investigates the outbreak. They consider the epidemiological triangle, the different stages of the Plasmodium parasite lifecycle and how it leads to malaria, and evaluate the broader societal factors and future implications of malaria in Sub-Saharan Africa. The case was designed for upper-level global health, public health, and human biology courses, but could also be adapted for general biology, health studies, infectious disease, and epidemiology courses.

In order to develop complex scientific explanations, students need to have many opportunities to grapple with a concept, look at it from various points of view, and analyze data representing different relationships. I plan the sequence and flow of my AP Environmental Science course strategically to ensure I am making these connections using a concept called "curriculum spiraling."

This interrupted case study introduces the topic of bacterial sporulation and cannibalism in Bacillus subtilis. The storyline follows Susan and her lab mates who are presenting research at a lab meeting when Susan falls asleep and dreams they are stranded on a deserted island. She makes connections between their fight for survival in the dream and the survival mechanisms of the bacteria they study in the lab. The benefits of sporulation under conditions of sustained stress are fairly obvious, but Susan's dream is used to examine the idea that sporulation may not always be beneficial and that bacteria would not want to commit to entering such a state in response to temporary stresses. Through the analysis of actual data from the scientific literature, students uncover a mechanism by which B. subtilis delays its commitment to sporulation by killing members of its own species to release nutrients (i.e., cannibalism). Originally developed for a general undergraduate microbiology course when discussing the structure and growth of prokaryotic cells, the case could also be used in an introductory biology course that emphasizes bacteria and data literacy.

The behavior of a person's genes doesn't just depend on the genes' DNA sequence - it's also affected by so-called epigenetic factors. Changes in these factors can play a critical role in disease.

Movement of ions in and out of cells is crucial to maintaining homeostasis within the body and ensuring that biological functions run properly. The natural movement of molecules due to collisions is called diffusion. Several factors affect diffusion rate: concentration, surface area, and molecular pumps. This activity demonstrates diffusion, osmosis, and active transport through 12 interactive models. Start by following the path of a molecule of dye in water, create concentration gradients on either side of a cell membrane and watch the movement of substances in and out of a cell, and monitor the movement of oxygen into red blood cells with and without hemoglobin.

Awesome interactive player

Article summarizing cell division with time lapse cell division video of 30hours pro vs eukaryotic division.

Learn the steps to completing a dihybrid cross! This video will show how to set up everyone's favorite 16 square Punnett square. This video uses vocabulary that was previously defined in the Amoeba Sisters Monohybrid Crosses video.

Evolutionary biologists have developed many techniques to analyze how male and female mating preferences have co-evolved. These studies combine animal behavior, sensory biology, phylogenetics, and neurobiology to observe the effects of male trait biases based on female receiver systems; that is, the "attractiveness" of the male trait to potential female mating partners.