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New immune system-boosting cancer drugs have in clinical trials saved the lives of many people with seemingly untreatable melanoma or lung cancer, but the drugs seem useless against colon cancer. One exception-a man with colon cancer whose metastatic tumors vanished for several years after he was treated in 2007-piqued researchers' interest. They suspected his recovery might have to do with the large number of mutations in his tumors. Now, a small clinical trial suggests that even cancer patients with types of tumors that were thought to be impervious to the new drugs could benefit if those malignancies have the right error-riddled DNA signature, a result that could help 3% to 4% of cancer patients.

This biomarker, called the KRAS-variant, is linked to more cancers than any other known inherited genetic mutation. It is present in 1 out of every 4 people with cancer, and in more than half of people who develop multiple cancers. KRAS-variant carriers tend to get highly aggressive and recurrent breast, ovarian, head and neck, lung and pancreatic cancers.

One of these days, there could well be a simple blood test that can help diagnose and track cancers. We aren't there yet, but a burst of research in this area shows we are getting a lot closer.

4:17 video Think of the ozone layer as Earth's sunglasses, protecting life on the surface from the harmful glare of the sun's strongest ultraviolet rays, which can cause skin cancer and other maladies. Ozone stinks. People who breathe it gag as their lungs burn. The EPA classifies ground-level ozone as air pollution. Yet without it, life on Earth would be impossible. A fragile layer of ozone 25 km above Earth's surface is all that stands between us and some of the harshest UV rays from the sun. The ozone molecule O3 blocks radiation which would otherwise burn skin and cause cancer. On Mars, which has no ozone layer to protect it, solar UV rays strafe the surface with deadly effect, leaving the apparently lifeless planet without the simplest of organic molecules in the upper millimeters of exposed Martian soil.

The idea of a general, quick and simple blood test for a diverse range of cancers just came closer to reality with news of a new study published in Nature Medicine.

1:15 video Uploaded on Oct 14, 2008 "What is Cancer?" is a 3D Animation which depicts the growth of a tumor.

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The physical connection between mother and fetus is provided by the placenta, an organ, built of cells from both the mother and fetus, which serves as a conduit for the exchange of nutrients, gasses, and wastes. Cells may migrate through the placenta between the mother and the fetus, taking up residence in many organs of the body including the lung, thyroid, muscle, liver, heart, kidney and skin. These may have a broad range of impacts, from tissue repair and cancer prevention to sparking immune disorders.

When women smoked daily during pregnancy, researchers identified 6,073 places where their babies' DNA was methylated differently from the DNA of nonsmokers' infants. Many of the differences were found on or near a collection of genes related to lung and nervous system development, smoking-related cancers and birth defects such as cleft lip and palate.

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