Spontaneous mutations play a key role in congenital heart disease -- ScienceDaily - 0 views
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Lottie Peppers on 16 Jan 15Although genetic factors contribute to congenital heart disease, many children born with heart defects have healthy parents and siblings, suggesting that new mutations that arise spontaneously -- known as de novo mutations -- might contribute to the disease. New research shows that about 10 percent of these defects are caused by genetic mutations that are absent in the parents of affected children.