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    Generic Cipro medicine should not be taken by expecting mothers because it is bad for the health of the unborn infant. Sometimes it can actually result in the miscarriage.

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    Renal tubular transport of methotrexate may be inhibited by concomitant administration of Ciprofloxacin potentially leading to increased plasma levels of methotrexate. This might increase the risk of methotrexate associated toxic reactions. Therefore, patients under methotrexate therapy should be carefully monitored when concomitant Ciprofloxacin ther

    published dose dosage frequency: as presccribed, twice daily for the period of 1 week

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    Some experts say the study has worrisome implications because at least 32, 000 people have been prescribed Cipro and other antibiotics after possible anthrax exposure. Many others have asked their physicians for a personal stash.

    In general, elderly patients may be more susceptible to drug-associated effects on the QT interval. Therefore, precaution should be taken when using Cipro with concomitant drugs that can result in prolongation of the QT interval for example, class IA or class III antiarrhythmics or in patients with risk factors for torsade de pointes for example, known QT prolongation, uncorrected hypokalemia. See WARNINGS/a

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    Generic Zithromax is used to treat many different types of infections caused by bacteria, such as respiratory infections, skin infections, ear infections, and sexually transmitted diseases. In children, it is used to treat middle ear infection, pneumonia, tonsillitis, and strep throat.

    The pharmacokinetics of ciprofloxacin are linear over the dose range of 200 to 400 mg administered intravenously. Comparison of the pharmacokinetic parameters following the 1st and 5th dose on a q 12 h regimen indicates no evidence of drug accumulation.

    Fluoroquinolones, including ciprofloxacin, may exacerbate muscle weakness in persons with myasthenia gravis. Avoid ciprofloxacin in patients with known history of myasthenia gravis see WARNINGS.

    Pharmacokinetic behavior of ciprofloxacin both in native cardiac and porcine valves treated in glutaraldehyde ; Kalmar P et al.; When judging a probable therapeutic success for antibiotic management of bioprosthetic endocarditis, sufficient drug levels in heterologous valve tissues play a very important role. The pharmacokinetic behavior of ciprofloxacin was investigated in native and porcine valvular tissues and compared with plasma levels during a 90- to 120-min period of surgery. Analysis was carried out by HPLC using excised valvular tissues Hancock T 505. In all, 15-20 patients were investigated in each group. The antibiotics were administered intravenously or per os. Tissue concentrations after onset of the procedures showed ciprofloxacin plasma concentrations of 2.09-0.47 micrograms g in the native and 3.98-1.99 micrograms/g in the heterologous valvular tissues.

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